237 research outputs found
Khizanah al-Hikmah : Jurnal Ilmu Perpustakaan, Informasi, dan Kearsipan (Analisis Bibliometrika pada Terbitan Tahun 2013-2018)
Full text linkMetode bibliometrika digunakan untuk menganalisis sebanyak 102 artikel dari Khizanah al-Hikmah : Jurnal Ilmu Perpustakaan, Informasi, dan Kearsipan, terbitan Universitas Islam Negeri Alauddin Makassar periode 2013–2018; untuk mengetahui distribusi artikel per tahun maupun per nomor, pola kepengarangan, jenis referensi yang digunakan, institusi yang berkontribusi serta penulis yang paling produktif. Data diunduh dari alamat: journal.uin-alauddin.ac.id/index.php/khizanah-al-hikmah , dan diolah menggunakan Microsof Excel 2010. Berdasarkan hasil dan pembahasan penelitian, dapat disimpulkan bahwa Khizanah al-Hikmah telah menerbitkan sebanyak 102 artikel dari 150 penulis, dengan penulis tunggal lebih banyak dibandingkan dengan penulis berkolaborasi, yang ditandai dengan nilai derajat kolaborasi sebesar 0,34. Mayoritas referensi yang digunakan adalah buku (65,15%), dengan jumlah halaman terbanyak berada pada kisaran 6-10 halaman (41,13%). Instansi kependidikan merupakan penyumbang artikel terbanyak, dan Universitas Islam Negeri Alauddin Makassar berada di urutan pertama (36 kali). Penulis laki–laki lebih produktif dibandingkan penulis perempuan dengan urutan pertama adalah Yunus Winoto (5 artikel).ABSTRACTA bibliometrical method used for analyzed a total of 102 articles from Khizanah Al –Hikamah, a journal in a LIS field, which published by UIN Alaudin Makassar since 2013-2018; to know the distribution of articles by year; distribution of articles by issue number; collaboration pattern and level of collaboration; length of published articles. Data downloaded from the site of Khizanah Al-Hikmah i.e.: journal.uin-alauddin.ac.id/index.php/khizanah-al-hikmah. The result and conclusion of this research was that from a total of 102 articles it found 150 author active as contributors, and an individual author more than a collaborative one, indicated by the collaboration level i.e. 0.34. Books mostly used in their references (65,15%), with the page length between 6-10 (41,13%). The academic institution was the most active as a contributor , and UIN Alaudin Makassar was the first rank (36 times). Man authors more productive than women and Yunus Winoto was the productive author
Relative Expression of CMyc MRNA in Human Glioma Cells and Its Relationship with the Degree of Malignancy
Full text linkRelative Expression of cMyc85Vol. 5, No. 2, Agustus 2017RESEARCH ARTICLERelative Expression of cMyc mRNA in Human Glioma Cells and its Relationship with the Degree of Malignancy Fidinny I. Hamid,1 Novi S. Hardiany,2* Febrial Hikmah,3 Syaiful Ichwan41Undergraduate Program FM Universitas Indonesia2Department of Biochemistry and Molecular Biology, FM Universitas Indonesia3Biomedical Sciences Program FM Universitas Indonesia4Department of Neurosurgery FM Universitas Indonesia -Dr Cipto Mangunkusumo General Hospital*Corresponding author: [email protected] 10 April 2016; Accepted 23 Agustus 2017DOI: 10.23886/ejki.5.7467AbstractPluripotency of cMyc genes may be one factor for the high glial cell differentiation in glioma thus it can become an alternative therapeutic target. The objective of the study is toanalyze the cMyc mRNA expression and its relationship with the degrees of glioma Malignancy. This is a cross-sectional study from 20 glioma samples with different degree of Malignancy from Dr. Cipto Mangunkusumo General Hospital, Jakarta during the period of October 2014 until February 2015. The mRNA obtained from glioma samples are converted to cDNA and then amplified. Relative quantification of cMyc mRNA expression is measured by calculating the cycle threshold values of Real Time RT PCR and normalized towards 18s rRNA to predict the relationship between the expression of cMyc and the degree of Malignancy. The cMyc expression is increased in accordance with the tumor grade. The cMyc expressions in high grade glioma are 17424.23 folds higher when calibrated to the normal cell, whereas the genes in lower grade tumors are expressed with the rate of 6167.35. Although the values obtained are not statistically significant, this research has strengthened molecular diagnosis, specifically pluripotency as the factor that gives a greater prognostic relevance than the histopathologic diagnosis. As a conclusion, there is a clinical tendency where the relative mRNA expression was higher in in glioma cMyc high degrees compared with low-grade glioma, however it is not statistically significant
Kearifan Syariat dan Hikmah dalam Puasa
Full text linkSuch a way of thinking was immediately followed by some Muslims especially the ulamas. So that some scholars give special attention by making works that are focused on studying the wisdom, philosophy and wisdom of the Shari'a. like Al Jurjawi with his book Hikmatu Tasyri 'Wafalsafatuhu, Mustafa As Siba'I with his work AhkamuS Shiyam Wa Falsafatuhu, Ad Dahlawy with his work Hujjatullah Al Balighah and other scholars. For this reason, the wisdom and wisdom of Shari'a are very urgent to be revealed in this contemporary era. Through this article the author feels the need to give a little review even though only a small part of the ocean of knowledge and the Shari'a of God which is applied to this people is about the wisdom of the Shari'a and wisdom in the obligation of fastingCara berpikir demikian segera dsikapi oleh sebagian umat islam terlebih para ulama. Sehingga sebagian ulama memberikan perhatian khusus dengan membuat karya yang memang difokuskan untuk mengkaji hikmah, Falsafah dan kearifan syariat. seperti Al jurjawi dengan kitabnya Hikmatu Tasyri’ Wafalsafatuhu, Musthafa As siba’I dengan karyanya AhkamuS Shiyam Wa Falsafatuhu, Ad Dahlawy dengan karyanya Hujjatullah Al Balighah serta para ulama lain. Karena alasan inilah, hikmah dan kearifan syariat menjadi sangat urgen untuk di ungkap di era kontemporer ini. Melalui tulisan ini penulis merasa perlu memberikan sedikit ulasan walau hanya bagian kecil dari samudera ilmu dan syariat allah swt yang diberlakukan bagi umat ini yaitu tentang kearifan syariat dan hikmah dalam kewajiban ibadah puasa
Rasionalitas Masyarakat dalam Swamedikasi Vitamin C selama Pandemi Covid-19
Full text linkBackground: Self-medication, both with herbs and chemical supplements, is people’s choice in dealing with the COVID-19 pandemic. Vitamin C is the most widely consumed supplement by the public on a self-medicated basis during the pandemic. Consumption of vitamin C as daily consumption must be an important concern of the community so that it becomes beneficial for the body. The aim of the study: This research was conducted to rationality of society in self-medication of vitamin C during the COVID-19 pandemic. Research method: This research is a descriptive study using a cross-sectional design. This research was conducted using a community self-medication rationality questionnaire for vitamin C, including the right indication, the right storage, the right dose, the right way of giving, the right time of administration and being aware of side effects. Result: Based on the 289 respondents in this study, it was illustrated that 90.3% of the respondents consumed vitamin C to increase their immune system and 67.1% of the respondents consumed vitamin C not only when they were sick. 76.1% of respondents knew the dose before consuming vitamin C, 86.5% of respondents consumed vitamin C <1000 mg/day, and 50.2% of respondents consumed vitamin C ≥1000 mg/week. As many as 88.2% of respondents consumed vitamin C after eating and 85.1% of respondents read the rules of consumption. As many as 68.9% of respondents read the side effects on the packaging, 85.8% of respondents did not experience side effects after consuming vitamin C, and 91.3% of respondents did not experience gastric irritation after consuming vitamin C. As many as 87.2% of respondents stored vitamin C at room temperature and 93.8% of respondents stored in a closed container. Conclusions: Public rationality in self-medication with vitamin C during the COVID-19 pandemic is a good category (82%)
MIKROBIOLOGI DAN PARASITOLOGI FARMASI
No full textMIKROBIOLOGI DAN PARASITOLOGI FARMASI
Penulis:
Febrial Hikmah, S.Si., M.Biomed.
Asri Sulfianti, S.Si., M.Biomed.
Sekar Asri Tresnaningtyas, S.Si., M.Biomed.
Ns. Ayamah, S.Kep., M.Kep.
Burhannuddin, S.Si., M.Biomed.
Mardhatillah Sariyanti, S.Si., M.Biomed.
Sheila Nurrahmah, SKM., M.Biomed.
Fitri Rahmi Fadhilah, S.Si., M.Biomed.
apt. Bheta Sari Dewi, S.Farm., M.Si.
Intan Tsamrotul Fu’adah, S.Si., M.Farm.
apt. Ayu Werawati, S.Si., M.Farm.
ISBN: 978-623-09-8399-3
Tebal: x + 169 hlm., 21 x 14.5 cm
Januari 2024
Editor: Febrial Hikmah, S.Si., M.Biomed.
Penata Letak: Liska Rahmayana
Penata Sampul: Adiktiya Harahap
Penerbit:
PT. ADIKARYA PRATAMA GLOBALINDO
Dusun Tegalsari RT 001/RW 004, Desa Jumoyo, Kec. Salam
Kabupaten Magelang, Provinsi Jawa Tengah
HP/WA: 08989999951, Email: [email protected]
Website: www.adpraglobalindo.my.i
The Role of Reactive Oxygen Species (ROS) in Cancer Stem Cells
Full text linkReactive Oxygen Species (ROS) are aerobic metabolic byproducts, mainly produced by mitochondria. Most types of cancer contain high amounts of ROS. An increase in endogenous ROS triggers adaptive changes, induces oxidative stress and cytotoxic. Oxidative stress can lead to cancer. But on the other hand, the radiotherapy treatment method induces the formation of ROS in the process of cell death. Resistance therapy in cancer cells is associated with high antioxidant enzymes that neutralize ROS in cancer cells. In addition, therapeutic resistance and recurrence are also associated with the presence of cancer stem cells (CSC). Several studies have shown that ROS levels are found to be low in cancer stem cells. Low levels of ROS are likely to play a role in the survival of cancer stem cells. Therefore, modulation of ROS levels in cancer stem cells can be used as an alternative therapy
EKSPRESI DAN REGULASI GEN: TEORI DAN APLIKASI
No full textPenulis: Febrial Hikmah, S.Si., M.Biomed.
Burhannuddin, S.Si., M.Biomed.
Silviatun Nihayah, S.Si., M.Biomed.
Gladies Mercya Grameinie, S.Si., M.Biomed.
Luthfiana Hardianingtyas, S.Si., M.Biomed.
dr. Steven, M.Biomed.
Raafqi Ranasasmita, M.Biomed.
Gita Wideani, S.Si., M.Biomed.
Miftahuz Zakiyah, LC., S.Pd., M.Biomed.
Kinasih Prayuni, M.Si.
dr. Agil Wahyu Wicaksono, M.Biomed.
Nur Imaniati Sumantri, S.Si., M.Biotek.
ISBN: 978-623-89118-7-5
Tebal: x + 222 hlm, 23 x 15,5 cm
Juli 2024
Editor : Febrial Hikmah, S.Si., M.Biomed.
Penata Letak : Fiana Astika
Penata Sampul : Alwi Viandika
Penerbit:
PT. ADIKARYA PRATAMA GLOBALINDO
Dusun Tegalsari, RT 001/RW 004, Desa Jumoyo, Kec. Salam
Kabupaten Magelang, Provinsi Jawa Tengah
HP/WA: 08989999951, Email: [email protected]
Website: www.adpraglobalindo.my.id
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ILMU BIOMEDIK UNTUK KESEHATAN MASYARAKAT
No full textILMU BIOMEDIK UNTUK KESEHATAN MASYARAKAT
Penulis:
Febrial Hikmah, S.Si., M.Biomed.
Luluk Hermawati, S.Pd., M.Biomed.
Gita Wideani, S.Si., M.Biomed.
Rizky Kusuma Wardani, S.Si., M.Biomed.
Ns. Diah Ayu Aguspa Dita, S.Kep., M.Biomed.
apt. Nenden Nurhasanah M.Farm.
Putri Rahayu Ratri, S.Si., M.Biomed.
dr. Yani Kurniawan, M.M., M.Biomed.
Zahara Fadilla, S.Si., M.Si.
Nikki Aldi Massardi, S.Si, M.Biomed.
apt. Gina Aulia, M.Farm.
Ns. Rustiana Tasya Ariningpraja, S.Kep., M.Biomed., AIFO.
ISBN: 978-623-09-8419-8
Tebal: xi + 196 hlm., 21 x 14.5 cm
Januari 2024
Editor: Febrial Hikmah, S.Si., M.Biomed.
Penata Letak: Liska Rahmayana
Penata Sampul: Adiktiya Harahap
Penerbit:
PT. ADIKARYA PRATAMA GLOBALINDO
Dusun Tegalsari RT 001/RW 004, Desa Jumoyo, Kec. Salam
Kabupaten Magelang, Provinsi Jawa Tengah
HP/WA: 08989999951, Email: [email protected]
Website: www.adpraglobalindo.my.i
Karakteristik Kitab Nadoman Nurul Hikmah Karya Hidayat Suryalaga
Full text linkPenelitian ini bertujuan untuk mengetahui karakteristik kitab Nadoman Nurul Hikmah beserta alasan penggunaannya. Dalam penelitian ini penulis menggunakan metode deskriptif analisis dan metode hermeneutik berdasarkan hubungan triadik (teks-reader/author-audience). Adapun sifat penelitian ini adalah penelitian pustaka (library research). Dalam prosesnya, penulis menggunakan dua kategori sumber data, sumber data primer dan sekunder. Dalam penelitian ini penulis menemukan beberapa hal mengenai karakteristik kitab Nadoman Nurul Hikmah. Karakter khas kitab Nadoman Nurul Hikmah tercermin pada dua aspek: Pertama, postur nadhomannya yang sederhana. Nadoman Nurul Hikmah cenderung lebih longgar dalam menerjemahkan bahasa sumber, Hidayat Suryalaga tidak menjadikan redaksi ayat sebagai sumber, tetapi ia berusaha menuangkan interpretasinya sendiri. Kedua, struktur dan gaya bahasa dalam Nadoman Nurul Hikmah Hidayat Suryalaga menggunakan struktur dan gaya bahasa yang sederhana, ia menggunakan bahasa Sunda yang populer dan kontekstual. Nadoman Nurul Hikmah jauh lebih tepat disebut sebagai terjemah tafsiriyah al-Qur’an daripada disebut sebagai sebuah kitab tafsir. Dalam kitabnya Nadoman Nurul Hikmah Hidayat Suryalaga menyertakan nilai-nilai kesundaan, hal tersebut tidak lepas dari tujuan ditulisnya kitab Nadoman Nurul Hikmah ini. Adapun nilai-nilai yang terdapat dalam kitab Nadoman Nurul Hikmah ini diantaranya adalah nilai kesundaan Silih Asih – Silih Asah – Silih Asuh, nilai kesundaan Rawayan Jati dan nilai kesundaan Sabilulungan
Relative Expression of cMyc mRNA in Human Glioma Cells and its Relationship with the Degree of Malignancy
No full textRelative Expression of cMyc85Vol. 5, No. 2, Agustus 2017RESEARCH ARTICLERelative Expression of cMyc mRNA in Human Glioma Cells and its Relationship with the Degree of Malignancy Fidinny I. Hamid,1 Novi S. Hardiany,2* Febrial Hikmah,3 Syaiful Ichwan41Undergraduate Program FM Universitas Indonesia2Department of Biochemistry and Molecular Biology, FM Universitas Indonesia3Biomedical Sciences Program FM Universitas Indonesia4Department of Neurosurgery FM Universitas Indonesia -Dr Cipto Mangunkusumo General Hospital*Corresponding author: [email protected] 10 April 2016; Accepted 23 Agustus 2017DOI: 10.23886/ejki.5.7467AbstractPluripotency of cMyc genes may be one factor for the high glial cell differentiation in glioma thus it can become an alternative therapeutic target. The objective of the study is toanalyze the cMyc mRNA expression and its relationship with the degrees of glioma malignancy. This is a cross-sectional study from 20 glioma samples with different degree of malignancy from Dr. Cipto Mangunkusumo General Hospital, Jakarta during the period of October 2014 until February 2015. The mRNA obtained from glioma samples are converted to cDNA and then amplified. Relative quantification of cMyc mRNA expression is measured by calculating the cycle threshold values of Real Time RT PCR and normalized towards 18s rRNA to predict the relationship between the expression of cMyc and the degree of malignancy. The cMyc expression is increased in accordance with the tumor grade. The cMyc expressions in high grade glioma are 17424.23 folds higher when calibrated to the normal cell, whereas the genes in lower grade tumors are expressed with the rate of 6167.35. Although the values obtained are not statistically significant, this research has strengthened molecular diagnosis, specifically pluripotency as the factor that gives a greater prognostic relevance than the histopathologic diagnosis. As a conclusion, there is a clinical tendency where the relative mRNA expression was higher in in glioma cMyc high degrees compared with low-grade glioma, however it is not statistically significant
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