58,810 research outputs found
Measurement of the ratio of prompt χ c to J / ψ production in pp collisions at √s = 7 TeV
No full textThe prompt production of charmonium χ c and J / ψ states is studied in proton-proton collisions at a centre-of-mass energy of √s = 7 TeV at the Large Hadron Collider. The χ c and J / ψ mesons are identified through their decays χ c → J / ψ γ and J / ψ → μ + μ - using 36 pb - 1 of data collected by the LHCb detector in 2010. The ratio of the prompt production cross-sections for χ c and J / ψ, σ (χ c → J / ψ γ) / σ (J / ψ), is determined as a function of the J / ψ transverse momentum in the range 2 < p T J / ψ < 15 GeV / c. The results are in excellent agreement with next-to-leading order non-relativistic expectations and show a significant discrepancy compared with the colour singlet model prediction at leading order, especially in the low p T J / ψ region
A journey among pairs of vertices: Computing Robots' paths for performing joint measurements
No full textThe problem of performing joint measurements recurs in many robotic applications, like constructing communication maps from signal strength samples gathered on the field. In spite of this, a theo ry supporting efficient algorithms has not been yet developed and ad hoc methods are usually employed. In this paper. we consider an environment represented by a metric graph and prove that the problem of Jointly performing measurements from given vertices is NP-hard when either the total traveled distance or the task comp letion time have to be minimized. Given the difficulty of finding optimal paths in an efficient way, we propose a greedy randomized approach able to cope with both the optimization objectives. In settings for which joint measurements must be taken for all pairs of vertices, we prove that a deterministic greedy algorithm achieves an O(m log n) approximation factor for the traveled distance object ive, where m is the number of robots and n the number of vertices, and an O(m2 log n) approximation factor for the completion time. Experiments in simulation show that our algorithms perform well in practice, also when compared to an ad hoc method taken from the literature
Quantification of pregabalin using hydrophilic interaction hplc-high-resolution ms in postmortem human samples: Eighteen case reports
No full textPregabalin is a drug for treating epilepsy, anxiety disorders and neuropathic pain. Cases of poisoning are rare, though some have been fatal. Concentrations of pregabalin in postmortem human samples and its distribution have very rarely been documented. As the literature is so scarce, we propose to report the concentrations in autopsy samples of 18 people who had been taking Lyrica®, including one case of a mixed overdose involving pregabalin. Analysis was carried out using an original Hydrophilic Interaction LIquid Chromatography (HILIC) technique coupled with a high-resolution mass spectrometer (m/z 160.1334 ± 5 ppm). The sensitivity of the technique enables a quick and simple treatment of the samples by protein precipitation. The method was validated in the whole blood with detection and quantification limits of 0.025 and 0.060 μg/mL, respectively. Pregabalin was a likely factor in the cause of death in 3 of the 18 cases. In the other individuals, the concentrations ranged from 0.4 to 17.0 in the peripheral blood, 1.5 to 11.1 in the central blood, 126.6 to 2004.6 in the urine and 10.5 to 58.3 μg/mL in the bile, with median values of 5.6, 4.6, 534.6 and 17.7, respectively. © The Author [2014]. Published by Oxford University Press. All rights reserved
Figure 11 in INTEGRATED PEST MANAGEMENT IN CONILON COFFEE
No full textFigure 11. Young (A) and adult (B) forms of the coffee sphinx moth caterpillar.Published as part of <i>Fornazier, M. J., Martins, D. S., Fanton, C. J. & Benassi, V. L. R. M., 2019, INTEGRATED PEST MANAGEMENT IN CONILON COFFEE, pp. 493-533 in Conilon coffee - The Coffea canephora produced in Brazil, Vitória, ES, Brasil :Incaper - Capixaba Institute for Research, Technical Assistance and Rural Extension</i> on page 2030, DOI: <a href="http://zenodo.org/record/10072573">10.5281/zenodo.10072573</a>
Evidence for the decay B0→J/ψω and measurement of the relative branching fractions of meson decays to J/ψη and J/ψη′
No full textFirst evidence of the B 0 → J / ψ ω decay is found and the B s 0 → J / ψ η and B s 0 → J / ψ η ′ decays are studied using a dataset corresponding to an integrated luminosity of 1.0 fb -1 collected by the LHCb experiment in proton-proton collisions at a centre-of-mass energy of sqrt(s) = 7 TeV. The branching fractions of these decays are measured relative to that of the B 0 → J / ψ ρ 0 decay:frac(B (B 0 → J / ψ ω), B (B 0 → J / ψ ρ 0)) = 0.89 ± 0.19 (stat) - 0.13 + 0.07 (syst),frac(B (B s 0 → J / ψ η), B (B 0 → J / ψ ρ 0)) = 14.0 ± 1.2 (stat) - 1.5 + 1.1 (syst) - 1.0 + 1.1 (frac(f d, f s)),frac(B (B s 0 → J / ψ η ′), B (B 0 → J / ψ ρ 0)) = 12.7 ± 1.1 (stat) - 1.3 + 0.5 (syst) - 0.9 + 1.0 (frac(f d, f s)), where the last uncertainty is due to the knowledge of f d / f s, the ratio of b-quark hadronization factors that accounts for the different production rate of B 0 and B s 0 mesons. The ratio of the branching fractions of B s 0 → J / ψ η ′ and B s 0 → J / ψ η decays is measured to befrac(B (B s 0 → J / ψ η ′), B (B s 0 → J / ψ η)) = 0.90 ± 0.09 (stat) - 0.02 + 0.06 (syst)
Identification of an achiral analogue of J-113397 as potent nociceptin/orphanin FQ receptor antagonist
No full textTo date, J-113397 represents the most potent and selective non peptide NOP receptor antagonist widely used in pharmacological
studies. However, the synthesis, purification, and enantiomer separation of this molecule, which contains two chiral centers,
is rather difficult and low-yielding. Here, we synthesized and tested a series of simplified J-113397 analogues to investigate the
importance of the stereochemistry and the influence of the substituents at position 3 of the piperidine nucleus and on the nitrogen
atom of the benzimidazolidinone nucleus. The compound coded as Trap-101, an achiral analogue of J-113397, combines a pharmacological
profile similar to that of the parent compound with a practical, high-yielding preparation
Fatal intoxication due to ackee (Blighia sapida) in Suriname and French Guyana. GC-MS detection and quantification of hypoglycin-A
No full textBetween 1998 and 2001 the deaths of 16 Surinamese children were recorded along the Maroni River, which forms the border between Suriname and French Guyana. After a metabolic origin was eliminated, ethnobotanical research in the field led to a hypothesis of intoxication through the ingestion of ackee. Ackee (Blighia sapida) is a large green leafy tree of West African origin. Its unripe fruit contains large quantities of two toxic molecules: hypoglycin-A and hypoglycin-B, the former being the more toxic. We have developed a GC-MS procedure allowing us to demonstrate the presence of hypoglycin-A in the gastric fluid of one of the deceased children, and to compare the content of hypoglycin-A in fruit collected on the road to Paramaribo in Suriname (5.1. mg/g) with samples from Burkina Faso (8.1. mg/g) and Jamaica (9.2. mg/g).Field research showed the misuse of this little-known plant by Maroon witch doctors. The Bushinengue witch doctors were informed about the dangers of ackee, and no new cases have been reported to date. © 2011 Elsevier Ireland Ltd
Measurement of the time-dependent CP asymmetry in B0 -> J/ψ KS0 decays
No full textThis Letter reports a measurement of the CP violation observables SJ/ψK0S and CJ/ψK0S in the decay channel B0→J/ψK0S performed with 1.0 fb−1 of pp collisions at s√=7 TeV collected by the LHCb experiment. The fit to the data yields SJ/ψK0S=0.73±0.07(stat)±0.04(syst) and CJ/ψK0S=0.03±0.09(stat)±0.01(syst). Both values are consistent with the current world averages and within
expectations from the Standard Model
A validated method for quantifying atractyloside and carboxyatractyloside in blood by hplc-hrms/ms, a non-fatal case of intoxication with atractylis gummifera l
No full textAtractyloside (ATR) and carboxyatractyloside (CATR) are diterpene glycosides that are responsible for the toxicity of several Asteraceae plants around the world. Mediterranean gum thistle (Atractylis gummifera L.) and Zulu impila (Callilepis laureola DC.), in particular, are notoriously poisonous and the cause of many accidental deaths, some suicides and even some murders. There is no current method for measuring the two toxins in biological samples that meet the criteria of specificity required in forensic medicine. We have endeavored to fill this analytical gap. Analysis was carried out using a solid-phase extraction and a high-performance liquid chromatography coupled with high-resolution tandem mass spectrometry detection. The method was validated in the whole blood with quantification limits of 0.17 and 0.15 mg/L for ATR and CATR, respectively. The method was applied to a non-fatal case of intoxication with A. gummifera. To the best of the authors' knowledge, this is the first time that a concentration of ATR and CATR in blood (883.1 and 119.0 mg/L, respectively) and urine (230.4 and 140.3 mg/L, respectively) is reported. ATR and CATR were quantified in A. gummifera roots by the standard method addition (3.7 and 5.4 mg/g, respectively)
Cerococcus catenarius Coccidia
No full text<p> <i>Cerococcus catenarius</i>:</p> <p>Coccidia is similar to the previous species, but have a hemispherical, less convex and smoother carapace.The lay is made under the carapace, from where the nymphs hatch forming lines; hence the name ‘catenarius'. These nymphs are fixed in the carapace cracks. Its oviposition capacity is very high and each female can lay up to 800 eggs.</p>Published as part of <i>Fornazier, M. J., Martins, D. S., Fanton, C. J. & Benassi, V. L. R. M., 2019, INTEGRATED PEST MANAGEMENT IN CONILON COFFEE, pp. 493-533 in Conilon coffee - The Coffea canephora produced in Brazil, Vitória, ES, Brasil :Incaper - Capixaba Institute for Research, Technical Assistance and Rural Extension</i> on page 2025, DOI: <a href="http://zenodo.org/record/10072573">10.5281/zenodo.10072573</a>
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