1,700 research outputs found

    Staley, Roberta

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    currentAcademic Biography BA (University of Calgary) Diploma Journalism (Grant MacEwan) MA Liberal Studies (Simon Fraser University) Roberta Staley is an author, a magazine editor and writer, and a documentary filmmaker who has reported from such places as Afghanistan, Papua New Guinea, Kenya, El Salvador, Haiti, Colombia, Cambodia, South Africa, Israel, and New Zealand. She currently edits Enterprise magazine, and is a contributor to BC Business, the South China Morning Post Magazine, Ms. Magazine, Trek, the Canadian Chemical News, Corporate Knights, and Sculpture, among others. She is also a columnist for Just for Canadian Doctors/Dentists magazines. Roberta has published her first book, titled Voice of rebellion : how Mozhdah Jamalzadah brought hope to Afghanistan. It is a biography of Afghan-Canadian human rights activist Mozhdah Jamalzadah

    Analogs in the treatment of chronic hepatitis B: real life experience with tenofovir and entecavir

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    INTRODUCTION: Tenofovir and entecavir are potent antiviral agents. By suppressing viral replication, they induce histological improvement and finally delay the progression of chronic hepatitis B and the development of complications. They are rarely associated with serious side effects. Our data from a real life experience support data from the literature and suggest some minimal difference that may be useful in tailoring therapy. PATIENTS AND METHODS: We retrospectively analyzed 54 patients affected by chronic hepatitis B (31 and 23 treated by entecavir and tenofovir, respectively). Eight patients were cirrhotic. At baseline and 4-12 and 24 weeks after starting therapy, biochemical and virological analysis were performed in all patients. Renal function tests (serum creatinine, creatinine clearance and blood urea), serum (calcium and phosphate blood level) and urine electrolyte were also studied. RESULTS: All the patients reached virological control within 24 weeks. Only in the group treated by tenofovir we observed a complete viral suppression within 12 weeks. Some patients treated with tenofovir showed increased creatinine clearance without serum creatinine alteration. No significant side effects were reported with the exception of one case of persistent headache in the entecavir group for which the drug was suspended. CONCLUSIONS: Entecavir and tenofovir are effective in suppressing viral replication in patients with chronic hepatitis B. Tenofovir is more potent than entecavir and viral replication is blocked within 12 weeks of therapy. Tenofovir administration is associated with slight increase of creatinine clearance without alteration of serum creatinine levels. The choice of one or the other should be made according to target and specific patients characteristics. In patients with high serum viral load where the complete and quick control of viral replication is the main target, tenofovir may represent the best choice

    Postface. Pour une esthétique hétéronome et plurielle

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    By discussing the essays collected in the volume, Roberta Dreon's paper focuses on the reasons that justify the very idea of a pragmatist aesthetic. This is done by considering that the association between the traditional, contemplative, disinterested, and anti-instrumental conception of aesthetic experience seems to preclude the possibility of characterizing it in practical or pragmatic terms. The author argues that this is achieved on the one hand by a rethinking of the very notion of the "aesthetic" found in the philosophies of James and Dewey. This allows for supporting the idea that artistic practices are grounded in ordinary experience, and particularly in their aesthetic-qualitative aspects. On the other hand, the author argues that Dewey's aesthetics was convincingly pragmatist to the extent that it lucidly focused on the consequences of the autonomist conception of art and proposed a continuist, meliorist, and pluralist alternative capable of providing effective contributions to democratic and inclusive development

    È possibile una teoria della razionalità? Il contributo di Hilary Putnam

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    Secondo Putnam argomentare sulla natura della razionalità è l’attività per eccellenza dei filosofi. Sulla traccia di Putnam, l’autore esamina le principali teorie della razionalità presenti nel pensiero contemporaneo. Tali concezioni hanno il difetto di essere unilaterali, mentre la nozione di razionalità si rivela complessa, quindi una teoria della razionalità è possibile, benché non possa essere definitiva. In seguito l’autore cerca di individuare le caratteristiche fondamentali che competono alla razionalità, in opposizione tanto alla concezione positivista quanto al relativismo.According to Putnam, arguing about the nature of rationality is the typical task of philosophers. Following Putnam, in this paper the author examines the main theories of rationality to be found in contemporary thought. Whereas such views betray their own one-sidedness, the idea of rationality is very complicated. As a consequence, a theory of rationality is possible, but cannot be definitive. Furthermore, the author tries to highlight the chief features pertaining to rationality, opposing positivsm as well as relativism

    First person - Roberta Besio

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    First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms (DMM), helping early-career researchers promote themselves alongside their papers. Roberta Besio is first author on 'Cellular stress due to impairment of collagen prolyl hydroxylation complex is rescued by the chaperone 4-phenylbutyrate', published in DMM. Roberta is a postdoc in the lab of Antonella Fortino at University of Pavia, Italy, investigating collagen and genetic diseases of the connective tissue

    Family altruism and incentives

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    The author builds on the altruistic model of the family, to explore the strategic interaction between altruistic parents, and selfish children, when children's efforts are endogenous. If there is uncertainty about the amount of income the children will realize, and if parents have imperfect information, the children have an incentive to exert little effort, and to rely on their parent's altruistically motivated transfers. Because of this, parents face a tradeoff between the insurance that bequests implicitly provide their children, and the disincentive to work prompted by their altruism. The author shows that if parents can credibly commit to a pattern of transfers, they will choose not to compensate children in bad outcomes, as much as predicted by the standard (no uncertainty, no asymmetric information) dynastic model of the family. Alternatively, parents may choose to forgo any insurance, and offer a fixed level of bequest, to elicit greater effort from their children. The optimal transfers structure that the author derives, reconciles the predictions of the altruistic family model, with much of the existing evidence on inter-generational transfers, which suggests that parents compensate only partially, or not at all, for earnings differentials among their children. Moreover, the author shows that Ricardian equivalence holds in this setup, except when non-negativity constraints are binding.Economic Theory&Research,Environmental Economics&Policies,Health Economics&Finance,Educational Sciences,Safety Nets and Transfers

    A imagem de Alessandro Baricco no Brasil

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    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão, Programa de Pós-Graduação em Estudos da Tradução, Florianópolis, 2013.Com a intenção de delinear o modo pelo qual o escritor italiano Alessandro Baricco se inseriu no sistema literário brasileiro e os caminhos percorridos pelos seus livros traduzidos, esta dissertação dá voz às experiências tradutórias de seus tradutores. A inserção de Bariccono Brasil tem seu início em 1997, através de uma proposição da Profa. Dra. Roberta Barni à editora Iluminuras da tradução de Oceano Mare. A partir daí, outras sete obras foram publicadas no Brasil, sendo três delas traduzidas por Roberta Barni e as outras quatro por quatro tradutores diferentes. De um lado, considera-se o tradutor como figura principal namediação entre culturas, e, de outro, se analisa a realidade desta figuradentro do sistema literário, sua invisibilidade, seus limites e o exercíciode sua profissão. A pesquisa conta, ainda, com críticas e resenhas referentes ao autor italiano publicadas em jornais consagrados no Brasil, considerando estas como parte constituinte da imagem de Baricco refletida em território nacional. Abstract : Intending to delineate the way the Italian writer Alessandro Baricco has been inserted in the Brazilian literary system and the paths his translated books have followed, this thesis gives voice to the translating experiences of his translators. Baricco's insertion in Brazil began in 1997, through a personal project of Dr. Roberta Barni, with her translation of Oceano Mare. Since then, seven other of his works have been published in Brazil, three of which were translated by Roberta Barni and the other four by four different translators. On the one hand,the translator is considered as the main figure in mediation betweencultures and, on the other, this figure's reality is analyzed within theliterary system: its invisibility, its limits and its professional practice. Criticisms and reviews of this Italian author published in well established Brazilian newspapers are also considered, with the understanding that they are part of Baricco's image reflected here

    The Roberta Jones Junior Theatre: A Model Children\u27s Theatre

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    Since its beginning in 1968, the Roberta Jones Junior Theatre, a children\u27s theatre, connected to the Parks and Recreation Department of Santa Clara, California, has been creating child-centered performances for young audiences. This thesis will explore the history of the Santa Clara/Roberta Jones Junior Theatre and discuss the components that have contributed to its forty-year success. For a children\u27s theatre to be successful it needs to be first centered on the learning of the children, in tune with the need of its community, and have a staff focused on the same goals. By examining the Roberta Jones Junior Theatre, the intension is to give a picture of its organizational structure, an analysis of its guiding principles, and how the author proposes to use it as a model for a children\u27s theatre in the future

    Werner Sombart and the global society. Anticipations from a classic author of sociology

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    The article examines the most salient works in which the sociologist Werner Sombart saw the dimension of globality as a social element, constitutive of mo- dernity and its future. The aim is to understand the role of globality, as an idea and a phenomenon, in the constitution in all aspects of society (economic, political, cultural, anthropological). The Works to which the article refers show a global society, one that goes from the time of Sombart to the present day, as the author had already envisioned in all their potentialities and criticalities
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