308 research outputs found
Omar Abed: 2025 Irma Black Award Gold Medal Acceptance Speech
No full textAuthor Omar Abed gives an acceptance speech for The Book That Almost Rhymed, illustrated by Hatem Aly (Dial Books for Young Readers)https://educate.bankstreet.edu/irma_black_awards/1015/thumbnail.jp
Kritik Metodologi: Perspektif Muhammad Abed Al-Jabiri
No full textABSTRACTAl-Jabiri is one of the Islamic thinkers who is concerned about efforts to reform in the realm of epistemology. The more value that this figure has is his ideas that always take inspiration from the Islamic tradition (Arabic), as much as possible avoiding the adoption of ideas derived from outside traditions, especially Europe, as well as other reform thinkers. The purpose of the study that the author did is to be able to know and understand the criticism methodology perspective abed al-jabiri. The method that the author uses in writing this work is in the form of literature studies, using cauldron analysis methods and using primary and secondary data sources. The conclusion of this research is Al-Jabiri criticized the epistemology of buhani, bayani, and irfani. According to abed al-Jabiri bayani based on burhani and built more rationally, then al-Jabiri completely reject the epistemology irfani because bayani can be eroded by irfani.Keywords: Abed al-Jabiri, Burhani, ‘Irfani, and Bayani.INTISARIAl-Jabiri merupakan salah satu tokoh pemikir Islam yang concern pada upaya pembaharuan dalam ranah epistemologi. Nilai lebih yang dimiliki tokoh ini adalah gagasan-gagasannya yang selalu mengambil inspirasi dari tradisi Islam (Arab), sebisa mungkin menghindari pengadopsian gagasan yang bersumber dari tradisi-tradisi luar, terutama Eropa, sebagaimana para pemikir pembaharuan yang lain. Adapun destinasi pengkajian yang penulis lakukan adalah agar dapat mengenal da
Kritik Nalar Arab: Eksposisi Epistemologi Bayani, ‘Irfani dan Burhani Muhammad Abed Al-Jabiri
No full textThis article anaylizes the philosophical and episthemological exposition of the contemporary Arab thinker, Muhammad Abed Al-Jabiri. As a leading Maroccan Muslim thinker, Abed al-Jabiri in renowned for his idea of combating‘irrationalism’ and that of promoting rasionalism in formulating Islamic thought. He comes to believe that Islamic teachings should be seen as a set of ideas com- patible with rationality and scientific notions. In his analyisis, Abed al-Jabiri pro- poses three streams of Islamic epistemological models: bayani, burhani and ‘irfani. By exploring these three epistemological concepts, the author goes further by exploring the authority of text in Muslim society and how to contextualize and read religious texts in modern time
Kritik Nalar Arab: Eksposisi Epistemologi Bayani, ‘Irfani dan Burhani Muhammad Abed Al-Jabiri
No full textThis article anaylizes the philosophical and episthemological exposition of
the contemporary Arab thinker, Muhammad Abed Al-Jabiri. As a leading
Maroccan Muslim thinker, Abed al-Jabiri in renowned for his idea of combating
‘irrationalism’ and that of promoting rasionalism in formulating Islamic thought.
He comes to believe that Islamic teachings should be seen as a set of ideas compatible
with rationality and scientific notions. In his analyisis, Abed al-Jabiri proposes
three streams of Islamic epistemological models: bayani, burhani and ‘irfani.
By exploring these three epistemological concepts, the author goes further by
exploring the authority of text in Muslim society and how to contextualize and
read religious texts in modern time.
Keywords: Islamic epistemology, Arab thought, rationalism, religious authorit
The performance enhancement of solar cooker integrated with photovoltaic module and evacuated tubes using ZnO/Acalypha Indica leaf extract: response surface study analysis
No full textIn this study, the effect of employing ZnO/Acalypha Indica leaf extract (ZAE) on the energy absorption of a coated portable solar cooker has been examined using an experimental setup. A prototypical model has been developed to corroborate in associating an investigative outcome per constituents of the experiments. The studied heat transfer process in ZAE is stable for harsh conditions. The design analysis and an estimation of the system performance were done given various parameters including the pressure of the vacuum envelope, bar plate coating digestion, emissivity, and solar rays. The fabricated solar was tested with and without ZAE to investigate the impact of this coating material on the solar cooker's thermal performance. To observe the performance of the new design, two figures of merit (F-1 and F-2) have been introduced. The factual food cooking assessments were for a family of four people, which operated in ZAE coating (0.8, 1.0, 1.2 mu m) of the solar cooker. The values of F-1 and F-2 for the proposed cooker were obtained as 0.1520 and 0.4235, respectively, which is intact with the BIS values. The results revealed that employing ZAE instead of a thermal NHC-PV solar cooker reduced the time required to boil 2 L of water for about 47 min. The overall thermal energy productivity of the solar cooker with electrical backup was obtained as 42.65%, indicating that the ZAE coating can improve the thermal efficiency by 10.35%
EPISTEMOLOGI BAYANI, IRFANI DAN, BURHANI MUHAMMAD ABED AL-JABIRI DAN IMPLEMENTASINYA DALAM MEREKONSTRUKSI KURIKULUM PENDIDIKAN AGAMA ISLAM
No full textIn recent times, the learning of Islamic Religious Education (PAI) has been perceived to be closer to a radical religious perspective and intolerant behavior. This perspective is very likely to develop because PAI is indeed constructed ideologically. This ideological style is because the PAI curriculum comes from products of Islamic thought in the dogmatic era of codification. PAI dogmatism is caused by the partiality of epistemology in the construction of the PAI curriculum. In order to be able to get out of the ideological-dogmatic style, this partiality must be stopped. PAI can utilize the epistemological division carried out by Muhammad Abed Al-Jabiri. Al-Jabiri developed three epistemologies in comprehensive Arabic reasoning. The epistemology consists of bayani, irfani, and burhani reasoning. These three epistemologies can break the epistemological partiality of PAI and replace it to become more comprehensive and integrative. This article aims to find the formula for the three epistemological relations of al-Jabiri in order to reconstruct the PAI curriculum. The author uses a literature study of the work of Muhammad Abed Al-Jabiri to find a theoretical framework for the epistemology of bayani, irfani, and burhani. This framework was then formulated in the PAI curriculum and looked for the form of relations between the three epistemologies. The author developed an integrative circular relationship pattern using a thematic learning approach on PAI. Through thematic learning, the construction of knowledge built into PAI learning is the result of the integration of three epistemologies that are circularly interconnected. Through this approach also, students will be accustomed to constructing knowledge using three epistemologies in an integrative and circular manner
Structure-activity relationships of small molecule direct inhibitors of Keap1-Nrf2 interaction
No full textThe Keap1–Nrf2–ARE system represents a crucial antioxidant defense mechanism that protects cells against oxidative stress-related diseases and inflammation. Activation of this system leads to elevated expression of a variety of antioxidant defense proteins and enzymes important for protection against oxidative damage, inflammation and tumorigenesis. Targeting Keap1–Nrf2 protein–protein interaction (PPI) has become a promising therapeutic strategy for several oxidative stress conditions and inflammatory diseases including chronic kidney disease, pulmonary fibrosis, chronic obstructive pulmonary disorder (COPD), and cancer chemoprevention. Several PPI inhibitors of Keap1–Nrf2 system have been reported; Tecfidera® is one of these inhibitors that is FDA approved for treatment of patients with relapsing multiple sclerosis. Inhibitors of Keap1–Nrf2 PPI are generally classified into direct and indirect inhibitors. Indirect inhibitors of Keap1–Nrf2 PPI are electrophilic species and can cause off-target side effects. Presently, scientists have been focusing on direct inhibitors of Keap1–Nrf2 PPI. In this work, we are focusing on the discovery of potent direct inhibitors of Keap1−Nrf2 PPI by performing a comprehensive structure-activity relationship (SAR) study in currently available scaffolds, or by designing new scaffolds. A fluorescence polarization (FP) assay has been used to evaluate the potency of synthesized compounds in vitro and cell-based assays have been used to test the most active compounds, resulting in the discovery of highly potent non-electrophilic Nrf2 activators. One of the best compounds discovered, 65v (LH835), has an IC50 of 144 ± 5 nM in the fluorescence polarization assay, and 1.7 ± 0.24 nM in a TR-FRET assay. Furthermore, we have demonstrated that the 65v (LH835) is an efficacious inducer of Nrf2 targeted genes in HepG2 C8 cells, exhibiting activity better than the well-known electrophilic activator, sulforaphane. Our direct inhibitors of Keap1–Nrf2 PPI could potentially be developed into drugs for the treatment of a number of oxidative stress-related diseases and conditions.Ph.D.Includes bibliographical referencesby Dhulfiqar Ali Abe
Pain Relief in Dental Local Anaesthesia with Vibrational Devices: Much Ado about Nothing? A Scoping Review
No full textIn recent years, vibrational devices have been introduced in order to reduce patient discomfort in some situations such as orofacial pain, orthodontic therapy, and injection of local anaesthetics. This article aims to review the clinical experience given by the use of these devices in local anaesthesia. The literature search was carried out on the main scientific databases for articles up to November 2022. Eligibility criteria were established, and pertinent articles selected. The results were classified by author, year, type of study, sample size and characteristics, purpose of use, type of vibrational device used, protocol used, and outcomes. Nine relevant articles were found. These are split mouth randomized clinical trials which evaluate the reduction in pain perception with different devices and different protocols of use in children, during procedures which require local analgesia by injection, compared with traditional local anaesthesia with premedication based on anaesthetic gels. Different objective and subjective scales of pain and discomfort perception were used. Although results are promising, some data, such as those relating to vibrational intensity and frequency, are not clear. Evaluations on samples varying by age and context of use are necessary to fully define the indications for this type of aid during oral rehabilitation procedures
Modelling the behaviour of unsaturated non-active clays in saline environment
No full textThe chemical composition of pore fluid and matric suction rule the mechanical behaviour of soils. In case of clays, their fabric changes in line with those variables. Since both the increase in matric suction and salinity cause a transition from an open to a close microstructure of low and medium activity clayey materials, a unique framework could tackle problems where salinity and saturation changes are expected. This paper presents a simple elasto-plastic model capable of reproducing the behaviour of unsaturated clayey soils in saline environments. Changes in the pore fluid composition are addressed through the use of osmotic suction as a variable. The proposed model extends the Barcelona Basic Model for partially saturated soils to consider the effect of osmotic suction. The model, implemented in the Thebes code, is calibrated for Boom Clay. The reproduced tests include mechanical loading at different matric and osmotic suctions in oedometric conditions, as well as more complex chemo-mechanical stress paths. Despite the simplicity of the formulation, the agreement between the experimental results and the simulations is encouraging. It seems that the modelling approach addresses the most important features of partially saturated soils with saline pore fluid which are slightly or moderately expansive
Grandes y pequeños ganaderos trashumantes en las sierras sorianas en el tránsito de la Edad Media a la Moderna
No full textEditada en la Universidad Carlos IIISe trata de llamar la atención en e este artículo sobre el papel de primera fila que jugaron los grandes señores de ganados en la actividad ganadera trashumante en el ámbito que abarcaba la cuadrilla mesteña de Soria durante los siglos XV y XVI. Para ello se establecen comparaciones entre el tamaño de sus rebaños y los de otros medianos y pequeños propietarios de la región, teniendo en cuenta entre otros indicios las noticias sobre sus ventas de lanas. Al mismo tiempo se profundiza en su caracterización desde el punto de vista sociopolítico, matizando algunas hipótesis que se han venido manejando para definir la base social mesteña y su evolución a lo largo del siglo XVI. Y por fin se repasan algunos aspectos referentes a la gestión de las explotaciones ganaderas trashumantes, que revelan la presencia de numerosos factores que hacían más rentables a las grandes frente a las medianas y pequeñas.Big sheep owners played a key role in nomadic sheeprearing in the Spanish region around Soria during the XVth. and XVIth. centuries. By using the volume of wool sales, the author compares the size of their flocks with those of other middle and small owners in the region and analyzes the owner’s sociopolitical profile, in order to qualify traditional hypotheses about the social basis of the «Mesta» and its evolution during the XVIth. Century. Lastly, some aspects of the management of sheeprrearing enterprises are examined, and its factors identified. In particular, the analyses focus on those aspects of sheeprearing that made big enterprises more profitable than the small ones.Publicad
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