18 research outputs found
Исследование качества подземных вод на территории научно-производственной базы южного лесничества Ильменского государственного заповедника
No full textКрупнова Татьяна Георгиевна – кандидат химических наук, кафедра экологии и природопользования, Южно-Уральский государственный университет. 454080, г. Челябинск,
пр. им. В.И. Ленина, 76. Е-mail: [email protected].
Машкова Ирина Вячеславовна – кандидат биологических наук, кафедра экологии и природопользования, Южно-Уральский государственный университет. 454080, г. Челябинск,
пр. им. В.И. Ленина, 76. E-mail: [email protected].
Кострюкова Анастасия Михайловна – кандидат химических наук, кафедра экологии и
природопользования, Южно-Уральский государственный университет. 454080, г. Челябинск,
пр. им. В.И. Ленина, 76. E-mail: [email protected].
Скалев Евгений Дмитриевич – студент, кафедра экологии и природопользования, Южно-
Уральский государственный университет. 454080, г. Челябинск, пр. им. В.И. Ленина, 76.
E-mail: [email protected]. T.G. Krupnova, South Ural State University, Chelyabinsk, Russian Federation,
[email protected]
I.V. Mashkova, South Ural State University, Chelyabinsk, Russian Federation,
[email protected]
A.M. Kostryukova, South Ural State University, Chelyabinsk, Russian Federation,
[email protected]
E.D. Scalev, South Ural State University, Chelyabinsk, Russian Federation,
[email protected]Работа посвящена проблеме качества подземных вод, использующихся для водоснабжения научно-производственной базы южного лесничества Ильменского государственного заповедника. Проведен химический анализ воды из трех скважин. Исследована взаимосвязь качества поверхностных и подземных вод. Выявлены антропогенные
причины несоответствия подземных вод гигиеническим требованиям к качеству питьевой воды. The present work deals with the quality of groundwater used for water supply of the
scientific and production center of the South forestry in Ilmensky State Reserve. Chemical
analyses of water from three wells have been conducted. The relationship of the quality of
surface water and groundwater has been investigated. Anthropogenic causes of the variation
of drinking water quality from the existing guidelines have been identified
Muscle Protease Activities in Salmo Trutta L. Inhabiting the Krivoi Ruchey River
No full textThe effects of size, age, and smoltification on muscle protein breakdown systems were studied in wild brown trout Salmo trutta L. inhabiting the Krivoi Ruchey River of the White Sea basin, Kola Peninsula. Activities of autophagy-related proteases including cathepsin B and D, calpains, and proteasome were assayed in the skeletal muscle of brown trout parr and smolt of different age group. Youngest fish group consisted of the most actively growing individuals possessed the higher rate of protein breakdown compared to older groups. Different patterns of muscle protein breakdown inherent to brown trout parr and smolts were shown to be associated with calpain system and cathepsin D activities. Thus, increased activity of these proteases in smoltifying individuals obviously results in amino acid accumulation that could be a mechanism of seawater tolerance required for seaward migration. This study is the first to show the age- and stage-related dynamics in protease activities in skeletal muscle of brown trout inhabiting the Krivoi Ruchey River. Growth- and smoltification-related patterns of protease activities were quite similar in brown trout from the Krivoi Ruchey River and previously studied rivers of the White Sea basin, however, some habitat-related differences were observed
Влияние послеростовых отжигов в кислородсодержащей атмосфере на микротвердость монокристаллического молибдата кальция CaMoO4
No full textMonocrystalline calcium molybdenum CaMoO4 is a well-known material. Recently, there has been a surge of interest in CaMoO4 due to a number of popular applications, such as working medium for a cryogenic scintillation bolometer. During growth CaMoO4 single crystals acquire a blue color due to the presence of defective centers, such as color centers, which is unacceptable for optical applications. To eliminate the coloration, annealing in an oxygen-containing atmosphere is used and then the necessary elements are prepared from the crystals by mechanical influences (cutting, polishing, etc.). In this regard, for the rational solution of issues arising in the manufacture of products from these crystals and their further practical use, the assessment of the mechanical properties of these crystalline materials is an urgent task. However, the results of studies of the mechanical properties of CaMoO4 are poorly presented, without taking into account anisotropy; there is a significant spread of data on the value of hardness by Mohs. For different authors, hardness varies from 3.5 to 6. In this paper, samples of single crystals of calcium molybdate in the initial state and after high-temperature annealing of different duration in an oxygen-containing atmosphere are studied. It is shown that prolonged annealing leads to discoloration of crystals. It has been established that calcium molybdate crystals are extremely brittle, the brittleness score of Zp crystals in the initial state is maximum and is 5, annealing leads to a decrease in the brittleness score to 4. The “viscosity” parameters are calculated by the Palmqvist S method. The nubs of complete destruction of Fpr prints were established, it was shown that annealing in an oxygen-containing atmosphere leads to an increase in Fpr by 2.5 times for the Z-cut, by 10 times for the X-cut. It is shown that the microhardness of crystals is characterized by anisotropy of the II kind: for all samples, the microhardness of the Z-cut is higher than the microhardness of the X-cut. The anisotropy coefficients of the microhardness of the KH samples are estimated. On the basis of the measured values of microhardness, the degrees of ionic bonds I are calculated.Монокристаллический молибдат кальция CaMoO4 — известный материал. Тем не менее последнее время наблюдается всплеск интереса к CaMoO4 в связи с рядом востребованных применений, в том числе использованием его в качестве рабочего материала для криогенного сцинтилляционного болометра. Монокристаллы CaMoO4 в процессе выращивания приобретают синюю окраску, обусловленную наличием дефектных центров, типа центров окраски, что неприемлемо для оптических применений. Для устранения окраски применяют отжиги в кислородсодержащей атмосфере, а затем из кристаллов изготавливают необходимые элементы путем механических воздействий (резка, полировка и др.). Поэтому для рационального решения вопросов, возникающих при изготовлении изделий из них и дальнейшем практическом использовании, оценка механических свойств этих кристаллических материалов является актуальной задачей. Результатов исследования механических свойств CaMoO4 мало, кроме того, они представлены без учета анизотропии. Наблюдается существенный разброс данных по значению твердости по Моосу у разных авторов: от 3,5 до 6. В данной работе приведены результаты исследования образцов монокристаллов молибдата кальция в исходном состоянии и после высокотемпературных отжигов разной продолжительности в кислородсодержащей атмосфере. Показано, что продолжительный отжиг приводит к обесцвечиванию кристаллов. Установлено, что кристаллы молибдата кальция являются чрезвычайно хрупкими, балл хрупкости Zp кристаллов в исходном состоянии максимален и составляет 5, отжиг приводит к снижению балла хрупкости до 4. Рассчитаны параметрами «вязкости» по методу Пальмквиста S. Установлены нагузки полного разрушения отпечатков Fпр, показано, что отжиг в кислородсодержащей атмосфере приводит к увеличению Fпр в 2,5 раза для Z-среза и в 10 раз для Х-среза. Показано, что микротвердость кристаллов характеризуется анизотропией II рода: для всех образцов микротвердость грани Z выше, чем микротвердость грани X. Оценены коэффициенты анизотропии микротвердости KH образцов. На основании измеренных значений микротвердости рассчитаны степени ионности связей I
Correction to Collaborators in Acknowledgments in: Decision-Making on Withholding or Withdrawing Life Support in the ICU: A Worldwide Perspective (Chest (2017) 152(2) (321–329), (S0012369217308206), (10.1016/j.chest.2017.04.176))
No full textThe authors have reported to CHEST that the collaborators from the ICON Investigators were omitted from the Acknowledgments in “Decision-Making on Withholding or Withdrawing Life Support in the ICU: A Worldwide Perspective” (Chest. 2017;152(2):321-329). The corrected Acknowledgments are as follows: ∗ICON Investigators: E. Tomas, E. Amisi Bibonge, B. Charra, M. Faroudy, L. Doedens, Z. Farina, D. Adler, C. Balkema, A. Kok, S. Alaya, H. Gharsallah, D. Muzha, A. Temelkov, G. Georgiev, G. Simeonov, G. Tsaryanski, S. Georgiev, A. Seliman, S. Vrankovic, Z. Vucicevic, I. Gornik, B. Barsic, I. Husedzinovic, P. Pavlik, J. Manak, E. Kieslichova, R. Turek, M. Fischer, R. Valkova, L. Dadak, P. Dostal, J. Malaska, R. Hajek, A. Židková, P. Lavicka, J. Starkopf, Z. Kheladze, M. Chkhaidze, V. Kaloiani, L. Medve, A. Sarkany, I. Kremer, Z. Marjanek, P. Tamasi, I. Krupnova, I. Vanags, V. Liguts, V. Pilvinis, S. Vosylius, G. Kekstas, M. Balciunas, J. Kolbusz, A. Kübler, B. Mielczarek, M. Mikaszewska-Sokolewicz, K. Kotfis, B. Tamowicz, W. Sulkowski, P. Smuszkiewicz, A. Pihowicz, E. Trejnowska, N. Hagau, D. Filipescu, G. Droc, M. Lupu, A. Nica, R. Stoica, D. Tomescu, D. Constantinescu, G. Valcoreanu Zbaganu, S. Adriana, V. Bagin, D. Belsky, S. Palyutin, S. Shlyapnikov, D. Bikkulova, A. Gritsan, G. Natalia, E. Makarenko, V. Kokhno, A. Tolkach, E. Kokarev, B. Belotserkovskiy, K. Zolotukhin, V. Kulabukhov, L. Soskic, I. Palibrk, R. Jankovic, B. Jovanovic, M. Pandurovic, V. Bumbasirevic, B. Uljarevic, M. Surbatovic, N. Ladjevic, G. Slobodianiuk, V. Sobona, A. Cikova, A. Gebhardtova, C. Jun, S. Yunbo, J. Dong, S. Feng, M. Duan, Y. Xu, X. Xue, T. Gao, X. Xing, X. Zhao, C. Li, G. Gengxihua, H. Tan, J. Xu, L. Jiang, Q, Tiehe, Q, Bingyu, Q, Shi, Z. Lv, L. Zhang, L. Jingtao, Z. Zhen, Z. Wang, T. Wang, L. Yuhong, Q, Zhai, Y. Chen, C. Wang, W. Jiang, W. Ruilan, Y. Chen, H. Xiaobo, H. Ge, T. Yan, C. Yuhui, J. Zhang, F. Jian-Hong, H. Zhu, F. Huo, Y. Wang, C. Li, M. Zhuang, Z. Ma, J. Sun, L. Liuqingyue, M. Yang, J. Meng, S. Ma, K. Lee, Y. Kang, L. Yu, Q, Peng, Y. Wei, W. Zhang, R. Sun, A. Yeung, W. Wan, K. Sin, M. Wijanti, U. Widodo, H. Samsirun, T. Sugiman, C. Wisudarti, T. Maskoen, N. Hata, Y. Kobe, Y. Shimomura, D. Miyazaki, S. Nunomiya, S. Uchino, N. Kitamura, K. Yamashita, S. Hashimoto, H. Fukushima, N. Nik Adib, L. Tai, B. Tony, R. Bigornia, R. Bigornia, R. Bigornia, J. Palo, S. Chatterjee, B. Tan, A. Kong, S. Goh, C. Lee, C. Pothirat, B. Khwannimit, P. Theerawit, P. Pornsuriyasak, A. Piriyapatsom, A. Mukhtar, A. Nabil Hamdy, H. Hosny, A. Ashraf, M. Mokhtari, S. Nowruzinia, A. Lotfi, F. Zand, R. Nikandish, O. Moradi Moghaddam, J. Cohen, O. Sold, T. Sfeir, A. Hasan, D. Abugaber, H. Ahmad, T. Tantawy, S. Baharoom, H. Algethamy, A. Amr, G. Almekhlafi, R. Coskun, M. Sungur, A. Cosar, B. Güçyetmez, O. Demirkiran, E. Senturk, H. Ulusoy, H. Atalan, S. Serin, I. Kati, Z. Alnassrawi, A. Almemari, K. Krishnareddy, S. Kashef, A. Alsabbah, G. Poirier, J. Marshall, M. Herridge, M. Herridge, R. Fernandez, G. Fulda, S. Banschbach, J. Quintero, E. Schroeder, C. Sicoutris, R. Gueret, R. Kashyap, P. Bauer, R. Nanchal, R. Wunderink, E. Jimenez, A. Ryan, A. Ryan, A. Ryan, A. Ryan, A. Ryan, A. Ryan, A. Ryan, D. Prince, J. Edington, F. Van Haren, A. Bersten, B. Richards, M. Kilminster, D. Sturgess, M. Ziegenfuss, S. O'Connor, J. Lipman, L. Campbell, R. Mcallister, B. Roberts, P. Williams, R. Parke, P. Seigne, R. Freebairn, D. Nistor, C. Oxley, P. Young, R. Valentini, N. Wainsztein, P. Comignani, M. Casaretto, G. Sutton, P. Villegas, C. Galletti, J. Neira, D. Rovira, J. Hidalgo, F. Sandi, E. Caser, M. Thompson, M. D'agostino Dias, L. Fontes, M. Lunardi, N. Youssef, S. Lobo, R. Silva, J. Sales Jr, L. Madeira Campos Melo, M. Oliveira, M. Fonte, C. Grion, C. Feijo, V. Rezende, M. Assuncao, A. Neves, P. Gusman, D. Dalcomune, C. Teixeira, K. Kaefer, I. Maia, V. Souza Dantas, R. Costa Filho, F. Amorim, M. Assef, P. Schiavetto, J. Houly, J. Houly, F. Bianchi, F. Dias, C. Avila, J. Gomez, L. Rego, P. Castro, J. Passos, C. Mendes, C. Grion, G. Colozza Mecatti, M. Ferrreira, V. Irineu, M. Guerreiro, S. Ugarte, V. Tomicic, C. Godoy, W. Samaniego, I. Escamilla, I. Escamilla, L. Castro Castro, G. Libreros Duque, D. Diaz-Guio, F. Benítez, A. Guerra Urrego, R. Buitrago, G. Ortiz, M. Villalba Gaviria, D. Salas, J. Ramirez-Arce, E. Salgado, D. Morocho, J. Vergara, M. Chung Sang, C. Orellana-Jimenez, L. Garrido, O. Diaz, D. Resiere, C. Osorio, A. De La Vega, R. Carrillo, V. Sanchez, A. Villagomez, R. Martinez Zubieta, M. Sandia, M. Zalatiel, M. Poblano, D. Rodriguez Gonzalez, F. Arrazola, L. Juan Francisco, S. A. Ñamendys-Silva, M. Hernandez, D. Rodriguez Cadena, I. Lopez Islas, C. Ballesteros Zarzavilla, A. Matos, I. Oyanguren, J. Cerna, R. Quispe Sierra, R. Jimenez, L. Castillo, R. Ocal, A. Sencan, S. Mareque Gianoni, A. Deicas, J. Hurtado, G. Burghi, A. Martinelli, I. Von Der Osten, C. Du Maine, M. Bhattacharyya, S. Bandyopadhyay, S. Yanamala, P. Gopal, S. Sahu, M. Ibrahim, D. Rathod, N. Mukundan, A. Dewan, P. Amin, S. Samavedam, B. Shah, D. Gurupal, B. Lahkar, A. Mandal, M. Sircar, S. Ghosh, V. Balasubramani, F. Kapadia, S. Vadi, K. Nair, S. Tripathy, S. Nandakumar, J. Sharma, A. Kar, S. Jha, K. Zirpe Gurav, M. Patel, A. Bhavsar, D. Samaddar, A. Kulkarni, M. Hashmi, W. Ali, S. Nadeem, K. Indraratna, A. Margarit, P. Urbanek, J. Schlieber, J. Reisinger, J. Auer, A. Hartjes, A. Lerche, T. Janous, E. Kink, W. Krahulec, K. Smolle, M. Van Der Schueren, P. Thibo, M. Vanhoof, I. Ahmet, G. Philippe, P. Dufaye, O. Jacobs, V. Fraipont, P. Biston, A. Dive, Y. Bouckaert, E. Gilbert, B. Gressens, E. Pinck, V. Collin, J. L. Vincent, J. De Waele, R. Rimachi, D. Gusu, K. De Decker, K. Mandianga, L. Heytens, X. Wittebole, S. Herbert, V. Olivier, W. Vandenheede, P. Rogiers, P. Kolodzeike, M. Kruse, T. Andersen, V. Harjola, K. Saarinen, M. Leone, A. Durocher, S. Moulront, A. Lepape, M. Losser, P. Cabaret, E. Kalaitzis, E. Zogheib, P. Charve, B. Francois, J. Lefrant, B. Beilouny, X. Forceville, B. Misset, F. Jacobs, F. Bernard, D. Payen, A. Wynckel, V. Castelain, A. Faure, P. Lavagne, L. Thierry, M. Moussa, A. Vieillard-Baron, M. Durand, M. Gainnier, C. Ichai, S. Arens, C. Hoffmann, M. Kaffarnik, C. Scharnofske, I. Voigt, C. Peckelsen, M. Weber, J. Gille, A. Lange, G. Schoser, A. Sablotzki, U. Jaschinski, A. Bluethgen, F. Vogel, A. Tscheu, T. Fuchs, M. Wattenberg, T. Helmes, S. Scieszka, M. Heintz, S. Sakka, J. Kohler, F. Fiedler, M. Danz, Y. Sakr, R. Riessen, T. Kerz, A. Kersten, F. Tacke, G. Marx, T. Volkert, A. Schmutz, A. Nierhaus, S. Kluge, P. Abel, R. Janosi, S. Utzolino, H. Bracht, S. Toussaint, M. Giannakou Peftoulidou, P. Myrianthefs, A. Armaganidis, C. Routsi, A. Xini, E. Mouloudi, I. Kokoris, G. Kyriazopoulos, S. Vlachos, A. Lavrentieva, P. Partala, G. Nakos, A. Moller, S. Stefansson, J. Barry, R. O'Leary, C. Motherway, M. Faheem, E. Dunne, M. Donnelly, T. Konrad, E. Bonora, C. Achilli, S. Rossi, G. Castiglione, A. Peris, D. Albanese, N. Stocchetti, G. Citerio, L. Mozzoni, E. Sisillo, P. De Negri, M. Savioli, P. Vecchiarelli, F. Puflea, V. Stankovic, G. Minoja, S. Montibeller, P. Calligaro, R. Sorrentino, M. Feri, M. Zambon, E. Colombaroli, A. Giarratano, T. Pellis, C. Capra, M. Antonelli, A. Gullo, C. Chelazzi, A. De Capraris, N. Patroniti, M. Girardis, F. Franchi, G. Berlot, M. Buttigieg, H. Ponssen, J. Ten Cate, L. Bormans, S. Husada, M. Buise, B. Van Der Hoven, A. Reidinga, M. Kuiper, P. Pickkers, G. Kluge, S. Den Boer, J. Kesecioglu, H. Van Leeuwen, H. Flaatten, S. Mo, V. Branco, F. Rua, E. Lafuente, M. Sousa, N. Catorze, M. Barros, L. Pereira, A. Vintém De Oliveira, J. Gomes, I. Gaspar, M. Pereira, M. Cymbron, A. Dias, E. Almeida, S. Beirao, I. Serra, R. Ribeiro, P. Povoa, F. Faria, Z. Costa-E-Silva, J. Nóbrega, F. Fernandes, J. Gabriel, G. Voga, E. Rupnik, L. Kosec, M. Kerin Povšic, I. Osojnik, V. Tomic, A. Sinkovic, J. González, E. Zavala, J. Pérez Valenzuela, L. Marina, P. Vidal-Cortés, P. Posada, A. Ignacio Martin-Loeches, N. Muñoz Guillén, M. Palomar, J. Sole-Violan, A. Torres, M. Gonzalez Gallego, G. Aguilar, R. Montoiro Allué, M. Argüeso, M. Parejo, M. Palomo Navarro, A. Jose, N. Nin, F. Alvarez Lerma, O. Martinez, E. Tenza Lozano, S. Arenal López, M. Perez Granda, S. Moreno, C. Llubia, C. De La Fuente Martos, P. Gonzalez-Arenas, N. Llamas Fernández, B. Gil Rueda, I. Estruch Pons, N. Cruza, F. Maroto, A. Estella, A. Ferrer, L. Iglesias Fraile, Q, Brigida, A. Quintano, M. Tebar, F. Frutos-Vivar, A. Reyes, A. Rodríguez, A. Abella, S. García Del Valle, S. Yus, E. Maseda, J. Berezo, A. Tejero Pedregosa, C. Laplaza, R. Ferrer, J. Rico-Feijoo, M. Rodríguez, P. Monedero, K. Eriksson, D. Lind, D. Chabanel, H. Zender, K. Heer, B. Frankenberger, S. Jakob, A. Haller, S. Mathew, R. Downes, C. Barrera Groba, A. Johnston, R. Meacher, R. Keays, P. Haji-Michael, C. Tyler, A. Ferguson, S. Jones, D. Tyl, A. Ball, J. Vogel, M. Booth, P. Downie, M. Watters, S. Brett, M. Garfield, L. Everett, S. Heenen, S. Dhir, Z. Beardow, M. Mostert, S. Brosnan, N. Pinto, S. Harris, A. Summors, N. Andrew, A. Rose, R. Appelboam, O. Davies, E. Vickers, B. Agarwal, T. Szakmany, S. Wimbush, K. Williams, R. Pearse, R. Hollands, J. Kirk-Bayley, N. Fletcher, B. Bray, D. Brealey. The online version of the article has been corrected
Higher Fluid Balance Increases the Risk of Death from Sepsis: Results from a Large International Audit∗
No full textObjectives: Excessive fluid therapy in patients with sepsis may be associated with risks that outweigh any benefit. We investigated the possible influence of early fluid balance on outcome in a large international database of ICU patients with sepsis. Design: Observational cohort study. Setting: Seven hundred and thirty ICUs in 84 countries. Patients: All adult patients admitted between May 8 and May 18, 2012, except admissions for routine postoperative surveillance. For this analysis, we included only the 1,808 patients with an admission diagnosis of sepsis. Patients were stratified according to quartiles of cumulative fluid balance 24 hours and 3 days after ICU admission. Measurements and Main Results: ICU and hospital mortality rates were 27.6% and 37.3%, respectively. The cumulative fluid balance increased from 1,217 mL (-90 to 2,783 mL) in the first 24 hours after ICU admission to 1,794 mL (-951 to 5,108 mL) on day 3 and decreased thereafter. The cumulative fluid intake was similar in survivors and nonsurvivors, but fluid balance was less positive in survivors because of higher fluid output in these patients. Fluid balances became negative after the third ICU day in survivors but remained positive in nonsurvivors. After adjustment for possible confounders in multivariable analysis, the 24-hour cumulative fluid balance was not associated with an increased hazard of 28-day in-hospital death. However, there was a stepwise increase in the hazard of death with higher quartiles of 3-day cumulative fluid balance in the whole population and after stratification according to the presence of septic shock. Conclusions: In this large cohort of patients with sepsis, higher cumulative fluid balance at day 3 but not in the first 24 hours after ICU admission was independently associated with an increase in the hazard of death
Simultaneous visualization of changes in perfusion and myocardial function of a transplanted heart in emergency cardiology
No full textIntroduction. In conditions of the Emergency Cardiology Department, a timely and differential diagnosis of myocardial pathology is especially important in the absence of visible focal changes and significant coronary artery stenosis. This group of patients includes recipients of a transplanted heart, when it is difficult to count on the high sensitivity of perfusion images alone. This can be explained by the diffuse, balanced distribution of ischemia.Objective. To present the possibilities of perfusion myocardial single photon emission computed tomography synchronized with electrocardiography for a detailed assessment of the functional condition of both ventricles of the transplanted heartMaterial and methods. We have presented three clinical case reports of the patients with different pathology of the transplanted heart who referred themselves to the emergency cardiology clinic and underwent electrocardiographysynchronized perfusion myocardial single photon emission computed tomography for diagnostic purposes.Results. In all the cases presented, the radionuclide study influenced making the diagnosis and changing the treatment tactics. In the first case, it was possible to identify focal myocardial changes, for which coronary angiography and percutaneous coronary intervention with thromboextraction were immediately performed. In the second case, the image analysis reflecting the function of the myocardium (polar maps of wall movement and systolic thickening) allowed us to note a low efficacy of treatment for the transplanted heart rejection. In the third clinical case, the initial single photon emission computed tomography suggested the inflammatory nature of changes in the myocardium, which was verified by the results of endomyocardial biopsy.Conclusion. In the presented clinical cases, the urgently performed electrocardiography-synchronized perfusion myocardial single photon emission computed tomography made it possible to perform invasive interventions in time and thereby contribute to the recovery of the graft functional state and patient's condition improvement
КВАНТОВОХИМИЧЕСКОЕ И ЭКСПЕРИМЕНТАЛЬНОЕ ИССЛЕДОВАНИЕ РЕАКЦИЙ НУКЛЕОФИЛЬНОГО ЗАМЕЩЕНИЯ В РЯДУ N-АЛКИЛ-3-НИТРО-1,2,4-ТРИАЗОЛОВ
No full textReactions of nucleophilic substitution of nitro group in N-alkyl-3-nitro-1,2,4-triazoles have been studied both experimentally and theoretically using DFT method. The standard enthalphy and Gibbs free energy of alkoxylation reactions of N-alkyl-3-nitro-1,2,4-triazoles in gas phase and aqueous solution have been calculated. The calculation results show that nucleophilic substitution reactions of N-alkyl-3-nitro-1,2,4-triazoles with alcohols and alcoholate anions are thermodynamically possible both in gas phase and in aqueous solution. Computed activation energies for reactions of N-alkyl-3-nitro-1,2,4-triazoles with methanol decrease in the series of ΔG≠S(for 1-isomer) >> ΔG≠S(for 4-isomer) > ΔG≠S(for 2-isomer). The calculation results are in good agreement with experimental data.С использованием современных квантовохимических и экспериментальных методов исследованы процессы нуклеофильного замещения нитрогруппы в ряду N-алкил-3-нитро-1,2,4-триазолов. Проведены расчеты стандартных энтальпий и энергий Гиббса реакций алкоксилирования N-алкил-3-нитро-1,2,4-триазолов в газовой и водной фазах. Согласно выполненным расчетам, реакции нуклеофильного замещения N-алкил-3-нитро-1,2,4-триазолов со спиртами и алкоголят-анионами термодинамически возможны как в газовой фазе, так и в водном растворе. На примере изомерных N-этил-3-нитро-1,2,4-триазолов показано, что расчетные значения энергии Гиббса активации реакций с метиловым спиртом в водном растворе уменьшаются в ряду ΔG≠S(для 1-изомера) >> ΔG≠S(для 4-изомера) > ΔG≠S(для 2-изомера). Результаты расчетов хорошо согласуются с данными экспериментального исследования процессов нуклеофильного замещения нитрогруппы в молекулах N-алкил-3-нитро-1,2,4-триазолов
The clinical relevance of oliguria in the critically ill patient: analysis of a large observational database.
No full textBACKGROUND
Urine output is widely used as one of the criteria for the diagnosis and staging of acute renal failure, but few studies have specifically assessed the role of oliguria as a marker of acute renal failure or outcomes in general intensive care unit (ICU) patients. Using a large multinational database, we therefore evaluated the occurrence of oliguria (defined as a urine output < 0.5 ml/kg/h) in acutely ill patients and its association with the need for renal replacement therapy (RRT) and outcome.
METHODS
International observational study. All adult (> 16 years) patients in the ICON audit who had a urine output measurement on the day of admission were included. To investigate the association between oliguria and mortality, we used a multilevel analysis.
RESULTS
Of the 8292 patients included, 2050 (24.7%) were oliguric during the first 24 h of admission. Patients with oliguria on admission who had at least one additional 24-h urine output recorded during their ICU stay (n = 1349) were divided into three groups: transient-oliguria resolved within 48 h after the admission day (n = 390 [28.9%]), prolonged-oliguria resolved > 48 h after the admission day (n = 141 [10.5%]), and permanent-oliguria persisting for the whole ICU stay or again present at the end of the ICU stay (n = 818 [60.6%]). ICU and hospital mortality rates were higher in patients with oliguria than in those without, except for patients with transient oliguria who had significantly lower mortality rates than non-oliguric patients. In multilevel analysis, the need for RRT was associated with a significantly higher risk of death (OR = 1.51 [95% CI 1.19-1.91], p = 0.001), but the presence of oliguria on admission was not (OR = 1.14 [95% CI 0.97-1.34], p = 0.103).
CONCLUSIONS
Oliguria is common in ICU patients and may have a relatively benign nature if only transient. The duration of oliguria and need for RRT are associated with worse outcome
СТАНДАРТНЫЕ ЭНТАЛЬПИИ ОБРАЗОВАНИЯ В ГАЗОВОЙ ФАЗЕ И ОТНОСИТЕЛЬНАЯ УСТОЙЧИВОСТЬ ТАУТОМЕРНЫХ ФОРМ С-АЛКОКСИ-1,2,4-ТРИАЗОЛОВ И ИЗОМЕРНЫХ N-МЕТИЛ-C-МЕТОКСИ-1,2,4- ТРИАЗОЛОВ: КВАНТОВОХИМИЧЕСКОЕ ИССЛЕДОВАНИЕ
No full textThe formation enthalpies of tautomeric forms of C-alkoxy-1,2,4-triazoles (alkoxy = OCH3, OC2H5, Oi-C3H7, Ot-C4H9) and isomeric N-methyl-C-methoxy-1,2,4-triazoles have been calculated by means of designed isodesmic and isomerisation reactions. The relative Gibbs energies for their tautomeric forms and isomers in aqueous solution have been calculated. N2-tautomers and isomers of C-alkoxy-1,2,4-triazoles wеre found to have the smallest values of formation enthalpy whereas N4-forms are less stable in gaseous phase. Increasing of electron donor properties of substituent leads to the stabilization of N2-tautomers in comparison with N1-tautomers. N1- and N2-tautomers and isomers have similar values of Gibbs free energy in aqueous solution. In contrast to gaseous phase, N1-derivatives of C-methoxy- and C-ethoxy-1,2,4-triazoles as well as N-methyl-C-methoxy-1,2,4-triazoles are more stable than corresponding N2-derivatives. This is due to higher polarity of N1-isomers in comparison with N2-ones. N4-derivatives are less stable in gaseous phase as well as in aqueous solution
Proceedings of the Workshop on the Okhotsk Sea and Adjacent Areas [Vladivostok, June 1995]
No full textI REPORT OF THE PICES WORKSHOP ON THE OKHOTSK SEA AND ADJACENT AREAS (pdf, 0.1 Mb)
1. Outline of the workshop
2. Summary reports from sessions
3. Recommendations of the workshop
4. Acknowledgments
II SCIENTIFIC PAPERS SUBMITTED FROM SESSIONS
1. Physical Oceanography Sessions (pdf, 4 Mb)
A. Circulation and water mass structure of the Okhotsk Sea and Northwestern Pacific
Valentina D. Budaeva & Vyacheslav G. Makarov
Seasonal variability of the pycnocline in La Perouse Strait and Aniva Gulf
Valentina D. Budaeva & Vyacheslav G. Makarov
Modeling of the typical water circulations in the La Perouse Strait and Aniva Gulf region
Nina A. Dashko, Sergey M. Varlamov, Young-Ho Han & Young-Seup Kim
Anticyclogenesis over the Okhotsk Sea and its influence on weather
Boris S. Dyakov, Alexander A. Nikitin & Vadim P. Pavlychev
Research of water structure and dynamics in the Okhotsk Sea and adjacent Pacific
Howard J. Freeland, Alexander S. Bychkov, C.S. Wong, Frank A. Whitney & Gennady I. Yurasov
The Ohkotsk Sea component of Pacific Intermediate Water
Emil E. Herbeck, Anatoly I. Alexanin, Igor A. Gontcharenko, Igor I. Gorin, Yury V. Naumkin & Yury G. Proshjants
Some experience of the satellite environmental support of marine expeditions at the Far East Seas
Alexander A. Karnaukhov
The tidal influence on the Sakhalin shelf hydrology
Yasuhiro Kawasaki
On the formation process of the subsurface mixed water around the Central Kuril Islands
Lloyd D. Keigwin
Northwest Pacific paleohydrography
Talgat R. Kilmatov
Physical mechanisms for the North Pacific Intermediate Water formation
Vladimir A. Luchin
Water masses in the Okhotsk Sea
Andrey V. Martynov, Elena N. Golubeva & Victor I. Kuzin
Numerical experiments with finite element model of the Okhotsk Sea circulation
Nikolay A. Maximenko, Anatoly I. Kharlamov & Raissa I. Gouskina
Structure of Intermediate Water layer in the Northwest Pacific
Nikolay A. Maximenko & Andrey Yu. Shcherbina
Fine-structure of the North Pacific Intermediate Water layer
Renat D. Medjitov & Boris I. Reznikov
An experimental study of water transport through the Straits of Okhotsk Sea by electromagnetic method
Valentina V. Moroz
Oceanological zoning of the Kuril Islands area in the spring-summer period
Yutaka Nagata
Note on the salinity balance in the Okhotsk Sea
Alexander D. Nelezin
Variability of the Kuroshio Front in 1965-1991
Vladimir I. Ponomarev, Evgeny P. Varlaty & Mikhail Yu. Cheranyev
An experimental study of currents in the near-Kuril region of the Pacific Ocean and in the Okhotsk Sea
Stephen C. Riser, Gennady I. Yurasov & Mark J. Warner
Hydrographic and tracer measurements of the water mass structure and transport in the Okhotsk Sea in early spring
Konstantin A. Rogachev & Andrey V. Verkhunov
Circulation and water mass structure in the southern Okhotsk Sea, as observed in summer, 1994
Lynne D. Talley
North Pacific Intermediate Water formation and the role of the Okhotsk Sea
Anatoly S. Vasiliev & Fedor F. Khrapchenkov
Seasonal variability of integral water circulation in the Okhotsk Sea
B. Sea ice and its relation to circulation and climate
V.P. Gavrilo, G.A. Lebedev & A.P. Polyakov
Acoustic methods in sea ice dynamics studies
Nina M. Pestereva & Larisa A. Starodubtseva
The role of the Far-East atmospheric circulation in the formation of the ice cover in the Okhotsk Sea
Yoshihiko Sekine
Anomalous Oyashio intrusion and its teleconnection with Subarctic North Pacific circulation, sea ice of the Okhotsk Sea and air temperature of the northern Asian continent
C. Waves and tides
Vladimir A. Luchin
Characteristics of the tidal motions in the Kuril Straits
George V. Shevtchenko
On seasonal variability of tidal constants in the northwestern part of the Okhotsk Sea
D. Physical oceanography of the Japan Sea/East Sea
Mikhail A. Danchenkov, Kuh Kim, Igor A. Goncharenko & Young-Gyu Kim
A “chimney” of cold salt waters near Vladivostok
Christopher N.K. Mooers & Hee Sook Kang
Preliminary results from a numerical circulation model of the Japan Sea
Lev P. Yakunin
Influence of ice production on the deep water formation in the Japan Sea
2. Fisheries and Biology Sessions (pdf, 2.8 Mb)
A. Communities of the Okhotsk Sea and adjacent waters: composition, structure and dynamics
Lubov A. Balkonskaya
Exogenous succession of the southwestern Sakhalin algal communities
Tatyana A. Belan, Yelena V. Oleynik, Alexander V. Tkalin & Tat’yana S. Lishavskaya
Characteristics of pelagic and benthic communities on the North Sakhalin Island shelf
Lev N. Bocharov & Vladimir K. Ozyorin
Fishery and oceanographic database of Okhotsk Sea
Victor V. Lapko
Interannual dynamics of the epipelagic ichthyocen structure in the Okhotsk Sea
Valentina I. Lapshina
Quantitative seasonal and year-to-year changes of phytoplankton in the Okhotsk Sea and off Kuril area of the Pacific
Lyudmila N. Luchsheva
Biological productivity in anomalous mercury conditions (northern part of Okhotsk Sea)
Inna A. Nemirovskaya
Origin of hydrocarbons in the ecosystems of coastal region of the Okhotsk Sea
Tatyana A. Shatilina
Elements of the Pacific South Kuril area ecosystem
Vyacheslav P. Shuntov & Yelena P. Dulepova
Biota of the Okhotsk Sea: Structure of communities, the interannual dynamics and current status
B. Abundance, distribution, dynamics of the common fishes of the Okhotsk Sea
Yuri P. Diakov
Influence of some abiotic factors on spatial population dynamics of the West Kamchatka flounders (Pleuronectidae)
Gordon A. McFarlane, Richard J. Beamish & Larisa M. Zverkova
An examination of age estimates of walleye pollock (Theragra chalcogramma) from the Sea of Okhotsk using the burnt otolith method and implications for stock assessment and management
Larisa P. Nikolenko
Migration of Greenland turbot (Reinhardtius hippoglossoides) in the Okhotsk Sea
Galina M. Pushnikova
Fisheries impact on the Sakhalin-Hokkaido herring population
Vidar G. Wespestad
Is pollock overfished?
C. Salmon of the Okhotsk Sea: biology, abundance and stock identification
Vladimir A. Belyaev, Alexander Yu. Zhigalin
Epipelagic Far Eastern sardine of the Okhotsk Sea
Yuri E. Bregman, Victor V. Pushnikov, Lyudmila G. Sedova & Vladimir Ph. Ivanov
A preliminary report on stock status and productive capacity of horsehair crab Erimacrus isenbeckii (Brandt) in the South Kuril Strait
Natalia T. Dolganova
Mezoplankton distribution in the West Japan Sea
Vladimir V. Efremov, Richard L. Wilmot, Christine M. Kondzela, Natalia V. Varnavskaya, Sharon L. Hawkins & Maria E. Malinina
Application of pink and chum salmon genetic baseline to fishery management
Vyacheslav N. Ivankov & Valentina V. Andreyeva
Strategy for culture, breeding and numerous dynamics of Sakhalin salmon populations
Alla M. Kovalevskaya, Natalia I. Savelyeva & Dmitry M. Polyakov
Primary production in Sakhalin shelf waters
Tatyana N. Krupnova
Some reasons for resource reduction of Laminaria japonica (Primorye region)
Lyudmila N. Luchsheva & Anatoliy I. Botsul
Mercury in bottom sediments of the northeastern Okhotsk Sea
Pavel A. Luk’yanov, Natalia I. Belogortseva, Alexander A. Bulgakov, Alexander A. Kurika & Olga D. Novikova
Lectins and glycosidases from marine macro and micro-organisms of Japan and Okhotsk Seas
Boris A. Malyarchuk, Olga A. Radchenko, Miroslava V. Derenko, Andrey G. Lapinski & Leonid L. Solovenchuk
PCR-fingerprinting of mitochondrial genome of chum salmon, Oncorhynchus keta
Alexander A. Mikheev
Chaos and relaxation in dynamics of the pink salmon (Oncorhynchus gorbuscha) returns for two regions
Yuri A. Mitrofanov & Larisa N. Lesnikova
Fish-culture of Pacific Salmons increases the number of heredity defects
Larisa P. Nikolenko
Abundance of young halibut along the West Kamchatka shelf in 1982-1992
Sergey A. Nizyaev
Living conditions of golden king crab Lithodes aequispina in the Okhotsk Sea and near the Kuril Islands
Ludmila A. Pozdnyakova & Alla V. Silina
Settlements of Japanese scallop in Reid Pallada Bay (Sea of Japan)
Galina M. Pushnikova
Features of the Southwest Okhotsk Sea herring
Vladimir I. Radchenko & Igor I. Glebov
Present state of the Okhotsk herring stock and fisheries outlook
Alla V. Silina & Ida I. Ovsyannikova
Distribution of the barnacle Balanus rostratus eurostratus near the coasts of Primorye (Sea of Japan)
Galina I. Victorovskaya
Dependence of urchin Strongylocentrotus intermedius reproduction on water temperature
Anatoly F. Volkov, Alexander Y. Efimkin & Valery I. Chuchukalo
Feeding habits of Pacific salmon in the Sea of Okhotsk and in the Pacific waters of Kuril Islands in summer 1993
Larisa M. Zverkova & Georgy A. Oktyabrsky
Okhotsk Sea walleye pollock stock status
Tatyana N. Zvyagintseva, Elena V. Sundukova, Natalia M. Shevchenko & Ludmila A. Elyakova
Water soluble polysaccharides of some Far-Eastern seaweeds
3. Biodiversity Program (pdf, 0.2 Mb)
A. Biodiversity of island ecosystems and seasides of the North Pacific
Larissa A. Gayko
Productivity of Japanese scallop Patinopecten yessoensis (IAY) culture in Posieta Bay (Sea of Japan)
III APPENDICES
1. List of acronyms
2. List of participants
(Document pdf contains 431 pages
