4,301 research outputs found
Maria Bersani
No full textLa voce illustra la biografia e l'apporto letterario dato da Maria Bersani alla letteratura per l'infanziaThe headword explains the biography and the contribution of the author Maria Bersani to the children's literatur
O curso de licenciatura em educação física da Universidade Federal de Santa Catarina: suas concepções de ensino e de educação física
No full textDissertação (mestrado) - Universidade Federal de Santa Maria. Centro de Educação Fisica e Desporto
Primary CD8+ T-cell response to soluble ovalbumin is improved by chloroquine treatment in vivo
No full textThe efficiency of cross-presentation of exogenous antigens by dendritic cells (DCs) would seem to be related to the level of antigen escape from massive degradation mediated by lysosomal proteases in an acidic environment. Here, we demonstrate that a short course of treatment with chloroquine in mice during primary immunization with soluble antigens improved the cross-priming of naïve CD8+ T lymphocytes in vivo. More specifically, priming of chloroquine-treated mice with soluble ovalbumin (OVA), OVA associated with alum, or OVA pulsed on DCs was more effective in inducing OVA-specific CD8 + T lymphocytes than was priming of untreated mice. We conclude that chloroquine treatment improves the cross-presentation capacity of DCs and thus the size of effector and memory CD8+ T cells during vaccination. Copyright © 2008, American Society for Microbiology. All Rights Reserved
Enhancement of T cell-mediated immune responses to whole inactivated influenza virus by chloroquine treatment in vivo
No full textCurrent influenza vaccines induce poor cross-reactive CD8+ T cell responses. Cellular immunity is generally specific for epitopes that are remarkably conserved among different subtypes, suggesting that strategies to improve the cross-presentation of viral antigens by dendritic cells (DC) could elicit a broadly protective immune response. Previous studies have shown that limited proteolysis within the endocytic pathway can favorably influence antigen processing and thus immune responses. Herein, we demonstrate that chloroquine improves the cross-presentation of non-replicating influenza virus in vitro and T cell responses in mice following a single administration of inactivated HI-X31 virus. CD8+ T cells were also recruited to lymph nodes draining the site of infection and able to reduce viral load following pulmonary challenge with the heterologous PR8 virus. These findings may have implications for vaccination strategies aimed at improving the cross-presentation capacity of DCs and thus the size of effector and memory CD8+ T cells against influenza vaccines
Direct Methanol (or Ethanol) Fuel Cell as Enzymatic or Non-Enzymatic Device, Used to Check Ethanol in Several Pharmaceutical and Forensic Samples
No full textIt was already demonstrated by our research group that a direct catalytic methanol (or ethanol) fuel cell (DMFC) device can be used also for analytical purposes, such as the determination of ethanol content in beverages. In the present research we extended the application to the analysis of several ethanol-based pharmaceutical products, i.e., pharmaceutical tinctures (dyes) and disinfectants. In recent work we have also shown that the use of alcohol dehydrogenase enzyme as a component of the anodic section of a direct catalytic methanol (or ethanol) fuel cell significantly improves the performance of a simple DMFC device, making it more suitable to measure ethanol (or methanol) in real samples by this cell. At the same time, we have also shown that DMFC can respond to certain organic compounds that are more complex than methanol and ethanol and having R(R’)CH-OH group in the molecule. Firstly, pharmaceutical dyes were analyzed for their ethanol content using the simple catalytic DMFC device, with good accuracy and precision. The results are illustrated in the present paper. Additionally, a detailed investigation carried out on commercial denatured alcoholic samples evidenced several interferences due to the contained additives. Secondly, we hypothesized that by using the enzymatic fuel cell it would be possible to improve the determination, for instance, of certain antibiotics, such as imipenem, or else carry out determinations of ethanol content in saliva and serum (simulating forensic tests, correlated to drivers “breath test„); even if this has already been hypothesized in previous papers, the present study is the first to perform them experimentally, obtaining satisfactory results. In practice, all of the goals which we proposed were reached, confirming the remarkable opportunities of the enzymatic (or non-enzymatic) DMFC device
Maria Paruszewska – the author of the Warmian anthem
No full textFor more than 70 years, historians have been trying to determine the authorship of the words to the song O Warmia my love, which became the anthem of Warmia. Although in May 1920 the “Gazeta Olsztyńska” published the song, stating its words were written by Maria Paruszewska from Poznań, its authorship was questioned. She was nonetheless the author of the Warmian Hymn. The song O Warmia, my love, was printed for the first time on 9 May 1920, together with Feliks Nowowiejski, nine days earlier than in Olsztyn, in the illustrated social and national weekly „Praca”, which was then edited in Poznań.Od przeszło 70 lat historycy próbowali ustalić autorstwo słów pieśni O Warmio moja miła, który stał się Hymnem Warmii. Chociaż jeszcze w maju 1920 roku w „Gazecie Olsztyńskiej” wydrukowano pieśń z informacją, że słowa napisała Maria Paruszewska z Poznania, to poddawano w wątpliwość jej autorstwo. Tymczasem to właśnie ona była autorką Hymnu Warmińskiego. Pieśń O Warmio moja miła wydrukowano po raz pierwszy 9 maja 1920 r. wraz z nutami Feliksa Nowowiejskiego, a dziewięć dni wcześniej niż w Olsztynie, w ilustrowanym tygodniku społeczno-narodowym „Praca”, redagowanym wówczas w Poznaniu
(In)famous writing : (r)existence in Child of the Dark by Carolina Maria de Jesus
No full textOrientador: Maria José Rodrigues Faria CoraciniDissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Estudos da LinguagemResumo: nserido no grupo de pesquisa, registrado no CNPq, "Vozes (In)fames: exclusão e resistência", sob a coordenação geral da Profa. Dra. Maria José R. F. Coracini, o presente trabalho pretendeu investigar, através da escrita do livro Quarto de despejo: diário de uma favelada (de Carolina Maria de Jesus), se a escrit(ur)a de si poderia ou não se configurar como dispositivo de (r)existência. E, em caso positivo: como, quando, em relação a quê e em que lugares ela se manifestaria. A pesquisa é pautada na perspectiva teórico-filosófica discursivo-desconstrutivista que se apoia nos estudos do Discurso (a partir do viés foucaultiano), da Psicanálise (lacaniana) e da Desconstrução (derrideana). Nosso objetivo específico é conhecer, compreender e trazer à baila o modo como a escrit(ur)a pode funcionar como (r)existência para a autora. E, como objetivo geral, visamos contribuir para os estudos de Linguística Aplicada - no que tange a questões sobre identidade e discurso -, colaborando também para a formação de professores e alunos, no que diz respeito à discussão de temas sociais. Analisamos a materialidade linguística, observando, principalmente, as representações de si, do outro, da favela, de leitura e escrita. Resultou de nossa pesquisa, a observação de indícios de que há uma (r)existência possibilitada pela escrit(ur)a de si. Tal (r)existência se dá em relação à condição econômico-social da autora, emergindo em três esferas, concernentes aos fatos de ela ser mulher, negra e favelada. Através da singularidade de sua escrit(ur)a, a qual emerge no entremeio das dualidades que aparecem na materialidade linguística, o sujeito (r)existe se diferenciando dos demais habitantes da favela e construindo um destino, um modo de ser/estar no mundo, diferente daquele que se esperaria para uma mulher negra, favelada e com pouca instruçãoAbstract: Included in the research group, registered in the CNPq, "Vozes (In)fames: exclusão e resistência", under general coordination by Prof. Dr. Maria José R. F. Coracini, the present work is intended to investigate, through the writing in the book Quarto de despejo: diário de uma favelada (by Carolina Maria de Jesus), if its writing may or may not configure a (r)existence device. And, in a positive case: how, when and in relation to what and which places it manifests itself. The research is characterized by the discursive-deconstructionist theoretic-philosophic perspective which bases itself on the studies of Discourse (according to the foucaultian line of thought), of Psychoanalysis (lacanian) and of Deconstruction (derridean). Our specific objective is to get to know, comprehend and bring forth the way in which writing may work as (r)existence for the author. And, as a general objective, we seek to contribute to the studies of Applied Linguistics ¿ in regards to questions regarding identity and discourse ¿ also collaborating with the development of teachers and students, when it comes to the discussion of social themes. We analyzed the linguistic materiality, observing, mainly, the representations of the self, the others, the slums, of reading and writing. Our research resulted in the observation of signals that there is a (r)existence made possible by the writing of the self. This (r)existence occurs in relation to the author¿s socioeconomic conditions, emerging in three spheres, concerning the fact that she is a black, impoverished woman. Through the singularity of her writing, which emerges in the middle of the dualities that occur in the linguistic materiality, the subject (r)exists differentiating herself from the rest of the slums¿ inhabitants and constructing a destiny, a way of being in the world, different than that which is expected of a black, impoverished woman with little educationMestradoLinguagem e SociedadeMestra em Linguística Aplicada1580354CAPE
Maria Montessori
No full textDr. Maria Montessori was born in Italy in 1870. At the age of 24 she became the first woman to receive a medical degree from the University of Rome. As assistant physician in the psychiatric clinic of the University of Rome, she became interested in the learning ability of mentally and physically atypical children. Her interest in this field was furthered by her reading of the success of Dr. Edward Sequin, a French physician, who was doing extensive work with the education of [people with learning disabilities].
Dr. Montessori founded the Orthophrenic School in Rome in 1898 and carried on much of her early work in this school. She also lectured at the University of Rome on pedagogical anthropology. In 1922 she was named inspector general of all schools in Italy. Her work was interrupted in 1933 because she was not able to accept the type of training the Mussolini regime was imposing on children. She left Italy in 1933 and did not return until 1947.
Madame Montessori spent the last of her life speaking and writing about the Montessori method in Spain, India, England, and the Netherlands. Her work was by now accepted for the normal child as well as the mentally handicapped. Dr. Maria Montessori died in 1952 while visiting the Netherlands.
The author of this article, Dr. John R. O\u27Donnell, is in his second year on the University of Dayton faculty. He has lectured widely and is looked upon as a resource person in the field of elementary school mathematics, an area in which he has written several books
r-Regularity
No full textWe provide a characterization of r-regular sets in terms of the Lipschitz regularity of normal vector fields to the boundary.Both authors would like to thank Armando P. Machado and Alessandro Margheri for valuable suggestions on the problems related to the Sturm-Liouville section. The first author was supported by "Fundacao para a Ciencia e a Tecnologia" through the Program POCI 2010 and the Project "Randomness in Deterministic Dynamical Systems and Applications" (PTDC-MAT-105448-2008). The second author was partially supported by the Research Centre of Mathematics of the University of Minho with the Portuguese Funds from the "Fundacao para a Ciencia e a Tecnologia", through the Project PEstOE/MAT/UI0013/2014
Camilla Del Soldato
No full textThe headword explains the biography and the contribution of the author Camilla Del Soldato to the children's literatur
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