1,845 research outputs found

    Adaptools 2.0: Implementation And Utilization Aspects [adaptools 2.0: Aspectos De Implementação E Utilização]

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    This paper present the new version of the tool AdapTools. This application provides mechanisms for implementation, execution and debugging of adaptive robots. We will focus on the aspects of implementation of the new structure of data and the model of non-deterministic execution, the new model of coding using the compiler AdapMap and improvement in the insertion of semantic routines, which makes it unnecessary to recompile the code of the tool.57527532Pistori, H., Neto, J.J., (2003) AdapTools: Aspectos de Implementação e Utilizaç ão, , Boletim técnico PCS - USPPistori, H., Neto, J.J., Costa, E.R., A free software for the development of adaptive automata (2003) IV International Forum on Free Software, 2Pistori, H., Neto, J.J., A free software for the development of adaptive automata Proceedings of the IV Workshop on Free Software - WSL (IV International Forum on Free Software), Porto Alegre, Brazil, June 5-7, 2003Neto, J., Moraes, M., Using adaptive formalisms to describe contextdependencies in natural language (2003) Lecture Notes in Artificial Intelligence, 2721, pp. 94-97. , N.J. Mamede, J. Baptista, I. Trancoso, M. das Graças, V. Nunes (Eds.): Computational Processing of the Portuguese Language 6th International Workshop, PROPOR 2003, JunePistori, H., (2003) Tecnologia Adaptativa Em Engenharia de Computação: Estado Da Arte e Aplicações, , Ph.D. dissertation, Universidade de São Paulo, São Paulo, BrasilNeto, J.J., (2004) Tecnologia Adaptativa, , (unpublished) São Paulo, Brasil, setembro deSantos, D.G., Pistori, H., Castro Jr., A.A., Neto, J.J., Adaptools: Umambiente gráfico de apoio ao desenvolvimento de software adaptativo SIMS - Simpósio de Informática e Mostra de Software Acadêmico, 2005Santos, D.G., Jesus, L., Aspectos de projeto e implementação do não- determinismo no AdapTools e seus impactos no aperfeiçoamento da ferramenta (2006) Monografia de Conclusão de Curso de Engenharia de Computação, , Campo Grande - MS, Brasil, dezembro de UCD

    Studying Red Blood Cell Agglutination By Measuring Membrane Viscosity With Optical Tweezers

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    The red blood cell (RBC) viscoelastic membrane contains proteins and glycoproteins embedded in a fluid lipid bilayer that are responsible for cell agglutination. Manipulating RBCs rouleaux with a double optical tweezers, we observed that the cells slide easily one over the others but are strongly connected by their edges. An explanation for this behavior could be the fact that when the cells slide one over the others, proteins are dragged through the membrane. It confers to the movement a viscous characteristic that is dependent of the velocity between the RBCs and justifies why is so easy to slide them apart. Therefore, in a first step of this work, by measuring the force as a function of the relative velocity between two cells, we confirmed this assumption and used this viscous characteristic of the RBC rouleaux to determine the apparent membrane viscosity of the cell. As this behavior is related to the proteins interactions, we can use the apparent membrane viscosity to obtain a better understanding about cell agglutination. Methods related to cell agglutination induced by antigen-antibody interactions are the basis of most of tests used in transfusion centers. Then, in a second step of this work, we measured the apparent membrane viscosity using antibodies. We observed that this methodology is sensitive to different kinds of bindings between RBCs. Better comprehension of the forces and bindings between RBCs could improve the sensibility and specificity of the hemagglutination reactions and also guides the development of new potentiator substances.6644Fontes, A., Fernandes, H.P., Barjas-Castro, M.L., Thomaz, A.A., Pozzo, L., Barbosa, L.C., Cesar, C.L., Red blood cell membrane viscoelasticity, agglutination and zeta potential measurements with double optical tweezers (2006) Proceedings of SPIE, 6088, pp. 296-305Eylar, E.H., Madoff, M.A., Brody, O.V., Oncley, J.L., The contribution of sialic acid to the surface charge of the erythrocyte (1962) J. Biol. Chem, 237, pp. 1992-2000Pollack, W., Reckel, R.P., A reappraisal of the forces involved in Hemagglutination (1977) Int Archs Allergy Appl. Immun, 54, pp. 29-42Fontes, A., Giorgio, S., de Castro Jr., A.B., Neto, V.M., Pozzo, L.Y., Marques, G.P., Barbosa, L.C., Cesar, C.L., Determination of femto Newton forces and fluid viscosity using optical tweezers: Application to Leishmania amazonensis (2005) Proceedings of SPIE, 5699, pp. 419-425Saffman, P.G., Delbruck, M., Brownian motion in biological membranes (1975) Proc. Nat. Acad. Sci. USA, 72, pp. 3111-3113Dimova, R., Danov, K., Pouligny, B., Ivanov, I.B., Drag of a solid particle trapped in a thin film or at an interface: Influence of surface viscosity and elasticity (2000) J. Colloid and Interface Science, 226, pp. 35-4

    Monitoring Activity Of Living Cells Marked With Colloidal Semiconductor Quantum Dots

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    Fluorescent semiconductor nanocrystals in quantum confinement regime (quantum dots) present several well known features which make them very useful tools for biological labeling purposes. Low photo-bleaching rates, high chemical stability, active surface allowing conjugation to living cells, explains the success of this labeling procedure over the commonly used fluorescent dyes. In this paper we report the results obtained with high fluorescent core-shell CdTe-CdS (diameter = 3-7 nm) colloidal nanocrystals synthesized in aqueous medium and conjugated to glucose molecules, incubated with living yeast cells, in order to investigate their glucose up-take activity.6088Menezes, F.D., Brasil Jr., A.G., Moreira, W.L., Barbosa, L.C., Ferreira, R.C., Cerar, C.L., Farias, P.M.A., Santos, B.S., (2005) Microelectronics Journal, 36, pp. 989-991Alivisatos, A., (1996) J. Phys. Chem., 100, p. 13226Castro, V., Farias, P.M.A., Santos, B.S., Menezes, F.D., Ferreira, R., Fontes, A., Lima, P.R.M., Cesar, C.L., (2004) Blood, 104 (11), pp. 741aBrus, L.E., (1991) Appl. Phys. A, 53, p. 465Weller, H., (1993) Adv. Mater., 5 (2), p. 88Brus, L.E., Harkless, J.A.W., Stillinger, F.H., (1996) J. Am. Chem. Soc., 118, p. 4834Schaller, R.D., Klimov, V.I., (2004) Phys. Rev. Lett., 92, p. 186601Gao, M., Sun, J., Dulkeith, E., Gaponik, N., Lemmer, U., Feldmann, J., (2002) Langmuir, 18, p. 4098Pileni, M.P., (2000) Catal. Today, 58, p. 151Moreira, W.L., Fontes, A., Neves, A.A.R., Thomas, A.A., Barbosa, L.C., De Menezes, F.D., Farias, P.M.A., Cesar, C.L., (2005) Proc. Spie: Genet. Eng. Opt. Probes Biomed. Appl. III, 5704, p. 36Farias, P.M.A., Santos, B.S., Menezes, F.D., Cesar, C.L., Fontes, A., Barjas-Castro, M.L., Castro, V., Ferreira, R.C., (2005) Journal of Biomedical Optics, 10 (4), pp. 44023-44026Farias, P.M.A., Santos, B.S., Menezes, F.D., Cesar, C.L., Fontes, A., Barjas-Castro, M.L., Castro, V., Ferreira, R.C., (2005) Journal of Microscopy, 219 (3), pp. 103-108Borchert, H., Talapin, D.V., Gaponik, N., McGinley, C., Adam, S., Lobo, A., Möller, T., Weller, H., (2003) J. Phys. Chem. B, 107, p. 9662Rockenberger, J., Trögr, L., Rogach, A.L., Tischer, M., Grundmann, M., Eychmüller, A., Weller, H., (1998) J. Chem. Phys, 108, p. 780

    Detection Of Metabolic Syndrome Features Among Childhood Cancer Survivors: A Target To Prevent Disease

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    Along with the growing epidemic of obesity, the risk of atherosclerosis, cardiovascular disease morbidity, and mortality are increasing markedly. Several risk factors for cardiovascular disease, such as visceral obesity, glucose intolerance, arterial hypertension, and dyslipidemia commonly cluster together as a condition currently known as metabolic syndrome. Thus far, insulin resistance, and endothelial dysfunction are the primary events of the metabolic syndrome. Several groups have recommended clinical criteria for the diagnosis of metabolic syndrome in adults. Nonetheless, in what concerns children and adolescents, there are no unified definitions, and modified adult criteria have been suggested by many authors, despite major problems. Some pediatric disease states are at risk for premature cardiovascular disease, with clinical coronary events occurring very early in adult life. Survivors of specific pediatric cancer groups, particularly acute lymphocytic leukemia, central nervous system tumors, sarcomas, lymphomas, testicular cancer, and following bone marrow transplantation, may develop metabolic syndrome traits due to: hormonal deficiencies (growth hormone deficiency, thyroid dysfunction, and gonadal failure), drug or radiotherapy damage, endothelial impairment, physical inactivity, adipose tissue dysfunction, and/or drug-induced magnesium deficiency. 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    Gait Variability and Kinematic Alterations in People with Diabetes Mellitus and Peripheral Neuropathy

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    Background: People with diabetes and peripheral neuropathy have been reported to show alterations in lower limb joint function compared to healthy non-diabetic people. Specifically the maximum angular movement available at certain joints can be reduced during static, non-weight bearing tasks. Limited joint range of motion has the potential to compromise balance and stability thereby increasing the risk of falling. It is unclear whether a reduction in the extent of movement available at the joints is reflected by a reduction in the amount of angular movement actually utilised during a functional task such as stair negotiation. The aim of this study was to determine if people with diabetes show reduced dynamic range of motion at the ankle, knee and hip joints during stair ascent and descent in comparison to controls. Falls risk during stair negotiation was calculated by measuring the degree of variability in dynamic joint range of motion. Methods: Data were generated from three groups: subjects with diabetes and peripheral neuropathy (DPN), diabetes without peripheral neuropathy (DM), and healthy controls (Ctl). The study was conducted in a gait laboratory using motion capture and related 3D software for analysis. Joint range of motion for the ankle, knee, and hip were captured during level walking, stair ascent, and descent. A seven step, bespoke staircase was fabricated for this purpose. Analysis of Variance (ANOVA) and Newman-Keuls tests were used to analyse the data. Results: Significantly reduced ankle range of motion, in the sagittal plane, was observed in the DPN group during stair ascent when compared to the controls. For stair descent, the DPN group demonstrated a significant increase in knee and hip ROM in the frontal plane, and also hip ROM in the transverse plane. No significant differences between the groups were identified for joint variability. Conclusions: People with DPN demonstrate alterations in dynamic range of motion at the lower limb joints during stair ascent and descent. The degree of angular movement utilised for both stair tasks was decreased at the ankle joint and this has the potential to undermine balance and stability. In contrast, angular movement at the knee and hip joints was increased in the frontal and transverse planes. This may compensate for impaired balance and stability by increasing the base of support to maintain balance and assist in foot clearance and placement. The specific combination of increased angular movement at the knee and hip may represent a compensatory stair gait strategy in response to reduced angular movement at the ankle joint

    Addition Of Allyltrichlorostannanes To Aldehydes: Application In The Synthesis Of 4-n-boc-amino-3-hydroxy Ketones

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    We wish to describe here the diastereoselective reaction between chiral N-Boc-α-amino aldehydes and achiral allyltrichlorostannanes leading to 1,2-syn-N-Boc-α-amino alcohols, which are treated with catalytic amounts of OsO4 in the presence of NaIO4 to provide the corresponding 4-N-Boc-amino-3-hydroxy ketones. © 2007 Elsevier Ltd. All rights reserved.493557561(1995) Biochemistry. 2nd ed., , Voet D., and Voet J.G. (Eds), Wiley, New YorkHannun, Y.A., Loomis, C.R., Merrill Jr., A.H., Bell, R.M., (1986) J. Biol. Chem., 261, p. 12604Merrill Jr., A.H., Sereni, A.M., Stevens, V.L., Hannun, Y.A., Bell, R.M., Kinkade Jr., J.M., (1986) J. Biol. Chem., 261, p. 12610Garner, P., Park, J.M., Malecki, E., (1988) J. Org. Chem., 53, p. 11061Herold, P., (1988) Helv. Chim. Acta, 71, p. 354Nimkar, S., Menaldino, D., Merrill, A.H., Liotta, D., (1997) Tetrahedron Lett., 38, p. 7687Menaldino, D.S., Bushnev, A., Sun, A.-M., Liotta, D.C., Symolon, H., Desai, K., Dillehay, D.L., Merrill, A.H., (2003) Pharmacol. Res., 47, p. 373Wiseman, J.M., McDonald, F.E., Liotta, D.C., (2005) Org. Lett., 7, p. 3155Dougherty, A.M., McDonald, F.E., Liotta, D.C., Moody, S.J., Pallas, D.C., Pack, C.D., Merrill Jr., A.H., (2006) Org. Lett., 8, p. 649Symolon, H., Schmelz, E.M., Dillehay, D.L., Merrill Jr., A.H., (2004) J. Nutr., 134, p. 1157Dias, L.C., Ferreira, E., (2001) Tetrahedron Lett., 42, p. 7159Dias, L.C., Ferreira, A.A., Diaz, G., (2002) Synlett, p. 1845Dias, L.C., Diaz, G., Ferreira, A.A., Meira, P.R.R., Ferreira, E., (2003) Synthesis, 4, p. 603Dias, L.C., Santos, D.R., Steil, L.J., (2003) Tetrahedron Lett., 44, p. 6861Dias, L.C., Ferreira, A.A., Santos, D.R., Ferreira, E., Diaz, G., Steil, L.J., Meira, P.R.R., Giacomini, R., (2003) Arkivoc, 10, p. 240Dias, L.C., Meira, P.R.R., Ferreira, E., (1999) Org. Lett., 1, p. 1335Righi, G., Ciambrone, S., (2004) Tetrahedron Lett., 45, p. 2103Lou, S., Westbrook, J.A., Schaus, S.E., (2004) J. Am. Chem. Soc., 126, p. 11440Machado, M.A., Harris, M.I.N.C., Braga, A.C.H., (2006) J. Braz. Chem. Soc., 17, p. 1440Zhang, Z.-W., Hu, J.-Y., (2006) J. Braz. Chem. Soc., 17, p. 1447Jung, C.-K., Krische, M.J., (2006) J. Am. Chem. Soc., 128, p. 17051Gennari, C., Pain, G., Moresca, D., (1995) J. Org. Chem., 60, p. 6248Bunnelle, W.H., Narayanan, B.A., (1987) Tetrahedron Lett., 28, p. 6261Mickelson, T.J., Koviach, J.L., Forsyth, C.J., (1996) J. Org. Chem., 61, p. 9617Einhorn, J., Einhorn, C., Luche, J.L., (1991) Synlett, p. 37Prasad, J.V.N.V., Rich, D.H., (1990) Tetrahedron Lett., 31, p. 1803Fehrentz, J.A., Castro, B., (1983) Synthesis, p. 676Golebiowski, A., Jacobsson, U., Jurczak, J., (1987) Tetrahedron, 43, p. 3063Jurczak, J., Golebiowski, A., (1989) Chem. Rev., 89, p. 149Stanfield, C.F., Parker, J.E., Kanellis, P., (1981) J. Org. Chem., 46, p. 4797Prasad, J.N.V.N., Rich, D.H., (1991) Tetrahedron Lett., 32, p. 5857Zanatta, N., Squizani, A.M.C., Fantinel, L., Nachtigall, F.M., Borchhardt, D.M., Bonacorso, H.G., Martins, M.A.P., (2005) J. Braz. Chem. Soc., 16, p. 1255Braibante, M.E.F., Braibante, H.T.S., Morel, A.F., Costa, C.C., Lima, M.G., (2006) J. Braz. Chem. Soc., 17, p. 184noteChérest, M., Felkin, H., Prudent, N., (1968) Tetrahedron Lett., 18, p. 2199Anh, N.T., Eisenstein, O., (1977) Nouv. J. Chem., 1, p. 61Masui, Y., Chino, N., Sakakibara, S., (1980) Bull. Chem. Soc. Jpn., 63, p. 464Futagawa, S., Inui, T., Shiba, T., (1973) Bull. Chem. Soc. Jpn., 46, p. 3308noteKnorr, A., Daub, J., (1997) Angew. Chem., Int. Ed., 36, p. 2817Schroeder, M., (1980) Chem. Rev., 80, p. 187DelMonte, A.J., Haller, J., Houk, K.N., Sharpless, K.B., Singleton, D.A., Strassner, T., Thomas, A.A., (1997) J. Am. Chem. Soc., 119, p. 9907Nagafuji, P., Cushman, M., (1996) J. Org. Chem., 61, p. 4999Konieczny, M., Cushman, M., (1992) Tetrahedron Lett., 33, p. 6939not

    Iowa State Journal of Research 53.1

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    Lee, D.K., and L.C. Promnitz. Sampling and estimation of hybrid poplar root systems. 1 Lassetter, J.S. Edaphic relationships in the Vicia ludoviciana complex. (Leguminosae) 13 Rollyson, C.E. Jr. The detective as historian: Josephine Tey's The Daughter of Time. 21 Kenyon, R.C. Winter food habits of the ring-necked pheasant (Phasianus colchius) in Iowa. 31 Berry, E.C., G.M. Ghidiu, and W.D. Guthrie. European corn borer" relationship of carbofuran uptake and corn genotypes for second-generation control. 35 Rupnow, A.A. Children, physiological sweating, teaching approaches, and anxiety. 41 Berry, E.C, and J.E. Campbell. European corn borer: relationship between stalk damage and yield losses in inbred and single-cross seed corn. 49 Author-title list of theses and dissertations, Iowa State University (Summer 1977- Spring 1978). 59</p

    International Riprap workshop, theory, policy and practice of erosion control using riprap, armour stone and rubble

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    J. Aguirre-Pe, R. Fuentes - Stability and weak motion of riprap at a channel bed A.F. Ahmed, F. EI-Gamal, M.M. Gasser - Deterministic and probabilistic design approaches of riprap as bank protection J.P. Ahrens - Design considerations for dynamic revetments G.J. Akkerman, E. Berendsen - Experimental validation of stability criteria for the design of rockfil/ closure dams N.W.H. Allsop - Stability of rock armour and riprap on coastal structures K.J. Bakker, M.B. de Groot, H.J. Verheij - A simple design relation for geometrie open filters in bed protections F.B.J. Barends - Geotechnical stability of riprap structures N.G. Bhowmik - Evaluation and utilization of biotechnical techniques and wil/ow posts for stabilizing eroding streambanks R.E.A.M. Boeters, F.C.M. van der Knaap, H.J. Verheij - Behaviour of armour layers of riprap bank protections along navigation channels K. Bruxvoort - Use of the 1991 Corps of Engineers riprap design procedure in mine reclamation F.W. Chamberlin, M.S. Meyers - A case study of the use of riprap in Rochester, Minnesota B.A. Christensen - Optimum design of riprap protected trapezoidal channels A.J. Combe, C.W. Solleau - Mississippi River - Gulf -Outlet, tests of riprap bank stabilization E.A. Dardeau Jr, K.J. KlIIgore Jr, A.C. Mlller - Using riprap to create or improve riverine habitat M.L. Dove - Standardized riprap gradations K.K. Duskaev - Principles of stone stability and the probability of stone break A. EI-Fiky, A. EI-Mongy, A.M. Talaat, M.M. Anwar - Wave energy dissipation by composite breakwater A.A. EI-Sayad, E.A. Abdel-Hafiez, A.M. Talaat - Effect of flow on riprap protected beds A. Franken, R.E. Jorissen, H.E. Klatter - Design ru/es for the use of riprap in closure works V.J. Galay, M. Zaki Abo EI Fotouh, M. EI Moattassem - Pilot project for bank proteetion along the river Nile D.H. Gray, R.D. Hryciw - Biotechnical stabilization of coastal landforms M.B. de Groot, J. Lindenberg - Pore pressures in riprap structures due to non-stationary loads M.B. de Groot, P. Meijers - Wave induced sliding of revetments D.J. Hagerty, A.C. Parola - Seepage effects in riprap armored embankments J. Haltiner - Environmentally sensitive approaches to river channel management F. Heezen - Risk analysis of a closure design: A case study J.E. Hite - Design, repair, and rehabilitatiqn of scour protection. Downstream from Inland. Navigation dam stilling basins J. van 't Hoft, M. Lindo, W.H. Tutuarima - Construction aspects of rock structures R.E. Jorissen, D.P. de Wilde, E. Berendsen - Design of the bed protection of the Rotterdam storm surge barrier G.J. Laan - Quality and quality control of stone for hydraulic structures R.J. Larson, G.A. Nicholson- Durability index for protection stone: A concept J.P. Latham, G.G. Gauss - The drop test for armourstone integrityKWP-collectio

    First observation of Bs → J/ψf0(980) decays

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    Using data collected with the LHCb detector in proton–proton collisions at a centre-of-mass energy of 7 TeV, the hadronic decay is observed. This CP eigenstate mode could be used to measure mixing-induced CP violation in the system. Using a fit to the π+π− mass spectrum with interfering resonances gives . In the interval ±90 MeV around 980 MeV, corresponding to approximately two full f0 widths we also find , where in both cases the uncertainties are statistical and systematic, respectively
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