471 research outputs found
Rifondare il tempo: il cinema di Chiara Cremaschi tra memorie fluttuanti e instabili presenti
No full textContributo dedicato alla pratica filmica e alla produzione di Chiara Cremaschi nel volume "CINEma oltre. Donne e pratiche audiovisive" in Italia volto ad indagare il panorama, ancora poco esplorato, delle attività delle artiste italiane che "dagli anni Settanta a oggi hanno scelto l'immagine in movimento come medium di espressione e talvolta di lotta". Muovendo tra Film Studies e Women's Studies, in un approccio multidisciplinare, il volume propone una selezione di artiste – dalle più conosciute alle emergenti note, emergenti – in un dialogo che interseca le esperienze storiche del cinema di ricerca e degli albori della videoarte, fino all'attualità degli ultimi anni, tenendo insieme le pioniere delle origini e le audaci sperimentatrici d'oggi. Il volume rappresenta uno degli output delle linee di ricerca che fanno perno nell'attività del Forum delle studiose di cinema e audiovisivi.
Con saggi di: Luisa Cutzu, Lucia Di Girolamo, Francesca Gallo, Sandra Lischi, Jennifer Malvezzi e Bianca Trevisan, Raffaella Perna, Simona Pezzano, Farah Polato, Maria Teresa Soldani, Deborah Toschi, Lucia Tralli
The New Era of Systemic Treatment for Hepatocellular Carcinoma: From the First Line to the Optimal Sequence
No full textHepatocellular carcinoma (HCC) represents the most common primary liver cancer and is considered a major global health problem as one of the leading causes of cancer-related death in the world. Due to the increase in life expectancy and the epidemiological growth of specific risk factors, such as metabolic dysfunction-associated steatotic liver disease (MASLD), the incidence of HCC is growing globally, and mortality rates are still high. Moreover, patients frequently present at an intermediate or advanced tumor stage, when curative treatments, such as surgical resection, liver transplantation or ablation are no longer applicable. In these cases, trans-arterial chemoembolization (TACE), trans-arterial radioembolization (TARE), and systemic therapy are the only suitable options to achieve disease control. The multi-kinase inhibitor Sorafenib has been the only systemic treatment available for unresectable advanced HCC for almost a decade, but in the last couple of years new therapeutic options have emerged. Recent advances in understanding the interactions between the tumor and its microenvironment, especially cancer immune escape, led to the advent of immunotherapy. Currently, first-line systemic treatment for HCC is represented by the combination of the immune checkpoint inhibitor (ICI) Atezolizumab plus Bevacizumab, an anti-vascular endothelial growth factor (VEGF) monoclonal antibody, but many other ICIs have been investigated, such as Nivolumab, Pembrolizumab, Durvalumab and Ipilimumab. However, the problem of second- and third-line therapies, and the correct sequence of treatments remains open and is not addressed in most studies. This explains the urge to find new systemic treatments that can improve the survival and quality of life in patients that can go beyond the first line of treatment. The aim of this paper is to offer a complete overview of the most recent innovations in systemic treatments for unresectable locally advanced and metastatic HCC, including emerging therapies, with a particular focus on treatment sequences. Moreover, we will provide an outlook on possible future approaches to patients who progress beyond first-line therapies
Video Presentazione online DV 16: Narrare il Medioevo
No full textPresentazione online del nuovo fascicolo della rivista Doctor Virtualis: n. 16 Narrare il Medioevo a cura di A. Salvestrini.
19 Novembre 2021
Vedi a lato: Locandina (PDF) e Video (URL)
Introducono:
Massimo Parodi, Amalia Salvestrini
Intervengono:
Luca Cardone, Marco Damonte, Gregorio Fiori Carones, Daphne Grieco, Rossana Guglielmetti, Costantino Marmo, Roberto Rossi, Marco Rossini, Marzio Zanantoni
Partecipano:
Maria Cristina Bartolomei, Alessandra Capacchione, Carla Casagrande, Aldo Andrea Cassi, Alfio Ferrara, Francesca Forte
Understanding continuity to recognize discontinuity
No full textIn this paper the a uthor comments on the contr ibution by Ant ónio P.
Ribeir o and Migu el M. Gonça lves (in this journ al) that offer a creat ive and unique
perspe ctive on maintenan ce and trans formatio n of problemat ic self-narr ative. From
here the author contribut es to the topic throu gh the explor ation of some issu es: a) the
relation, in the dialogical process of self -narrativ e constructi on, between semi otic
proces ses that give voice to the semantic opposi tion and semiotic proces ses that give
voice to the contr adictory; b) the relation between sam eness and ipseity in the self-narrative proces s; c) the role of a pathemi c axis of meaning in the gene ration proces s
of self -narrativ es. A final refl ection is done on narrative as a device of clin ical
intervent ion in which the author makes a distinction between methods based on the
recogni tion and extens ion of variabili ty and met hods based on the recogni tion of
perm anency so to get to varia bility
Imperfezioni. In forma di introduzione
No full textLuogo dello scarto e del ritardo, della mancata corrispondenza a modelli intesi come assoluti, l’imperfezione può diventare uno spazio di libertà dove elaborare pratiche impensate e impreviste, lontane dagli standard e fuori dal canone.
A partire da questa idea di imperfezione, il volume propone letture e attraversamenti della storia del cinema e dell’audiovisivo dal punto
di vista delle donne, muovendosi dal muto alla contemporaneità. Ciò che emerge è un inedito paesaggio mediale, discontinuo e ttamente abitato, capace di restituire la di erenza femminile in azione
Les Osservazioni de Filippo Maria Pagano sur la Constitution de Cadix à Naples en 1820
No full textThe constitutional debate ongoing in the south of the Italian peninsula during the « nonimestre » had been deep and intellectuals such as Filippo Maria Pagano, a career military person and author of remarkable Istoria del Regno di Napoli. Pagano’s Osservazioni alla Costituzione Spagnuola, published in 1820, focused on some critical aspects of the « reception » of the Constitution of Cadiz and insisted on a specificities of the Neapolitan context, retrieving the criticism by Vincenzo Cuoco to the Francesco Mario Pagano’s Progetto di Costituzione for the 1799 Neapolitan Republic. The study aims to explain in the major events leading to the grant of the Cadiz Constitution by King Ferdinand I ; then after a brief report on the parliamentary debate, it will focus on the Pagano’s Osservazion
The Poetics of Marām al-Maṣrī
No full textThe Siryan poet Maram al-Maṣri, is a versatile author and courageous innovator in modern arabic poetry. The paper presents a study of the poetic work of one of an interesting author in the panorama of contemporary Arabic poetry. Maram al-Maṣri migrated many decades ago In France where she actually lives. A woman of great courage who deals with the issues of women freedom. Author of several poetic collections, she devoted much of her commitment to the dissemination of her ideas on the emancipation of women. Recently, she has been at the forefront of the protests against the civil war in her country. Her poetics show great ability in presenting a new reading of classical themes using a language particularly simple and strongly rhythmic
Martino Buonocore e il palazzo Carafa della Spina nel Settecento
No full textThe essay explores the figure of Martino Buonocore and his main work, the renovation of the Carafa della Spina palace in Naples. For this work, executed in the 18th century, there have been conflicting interpretations, which tend to attribute its conception to Ferdinando Sanfelice. This hypothesis has been completely debunked by the investigation of primary sources. Crucial to Buonocore’s production is the family collaboration and the sharing of labour in his father Filippo's studio; the latter was the author of the magnificent 18th-century renovation of the palace in Corigliano. Martino was the author of the church of Santa Maria Verticoeli in Naples and had a 20-year commission for the Certosa di Padula. He worked for a long time with Gennaro Maria Carafa, who was to work on the Posillipo casino and the San Domenico palace. This last work will consolidate the long professional and friendly relationship between the prince and the architect.Il saggio esplora la figura di Martino Buonocore e la sua opera principale, la ristrutturazione del palazzo Carafa della Spina a Napoli nel XVIII secolo, per la quale ci sono state interpretazioni contrastanti, protese ad ascriverne l’ideazione a Ferdinando Sanfelice, ipotesi attributiva del tutto fugata dall’indagine sulle fonti primarie. Nella produzione di Martino risulta cruciale la collaborazione familiare e la condivisione delle maestranze coinvolte nella bottega artigiana del padre Filippo, già autore della magnifica rifattione settecentesca del palazzo Corigliano. Nel catalogo delle sue opere emergono la chiesa di Santa Maria Verticoeli a Napoli, l’incarico ventennale per la Certosa di Padula e la lunga collaborazione con Gennaro Maria Carafa, che lo impegnerà nel casino di Posillipo e nel palazzo in San Domenico, opera che consoliderà la lunga relazione professionale e amicale tra il principe e l’architetto
Un nuovo saggio su Seneca
No full textrecensione all'ultima traduzione di un'antologia senecana dell'esistenzialista spagnola Maria Zambrano. L'antologia è preceduta da un saggio in cui l'autrice valorizza l'indipendenza del saggio senecano dagli eventi esterni, e la sua lotta inesausta per la libertà di pensiero.Review the latest translation of an anthology Seneca dell'esistenzialista Spanish Maria Zambrano. The anthology is prefaced by an essay in which the author emphasizes the independence of the wise Seneca by external events, and his tireless fight for freedom of thought
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