142 research outputs found
ENTREPRENEURSHIP AND FEMALE ENTREPRENEURSHIP IN MARAMURES COUNTY
No full textInitiating and developing a business involves a considerable risk and a sustained effort in order to defeat the inertia against what is new. The person initiating a business, assuming the responsibility and risk of its development and benefiting from theentrepreneurship, female entrepreneurship, profit, businesses
Nichts für Schnellbetrachter: Doina Ioanids "Poesie der leichten Töne"
No full textThe article presents Doina Ioanid and her prose poems. In her poems, Ioanid records in detailed manner everyday life episodes in order to capture the fragile, authentic, genuine aspects and thus the poetry of simple life. The author use the apparent trivial aspects of life for selfreflections and for her escapes into fantasy. Her poems is the result of a cautious language precision and frugality, which make of DoinaIoanid one of the most representative and gifted Romanian poets of the young generation
ACTIVITIES OF THE SONG AND DANCE ENSEMBLE DOINA IN 1942-1944
No full textThe State Academic Chapel ”Doina” is the oldest and most significant performing choir in the Republic of Moldova. An
important stage of development occurred during the Second World War: in 1942, the chapel was reorganized into the Doina
Song and Dance Ensemble, which brought together musicians, singers and dancers from the Moldovan State Philharmonic.
The author considers issues related to the life of the choir collective during the evacuation period and the implementation
of concert activities in military field conditions. The geography of the ensemble’s tours is studied, the selection of the repertoire
and the interaction of the administration with composers, poets, and heads of other organizations are analyzed. Particular
attention is paid to the organization of everyday life and the life of the artists of the Doina Ensemble in wartime conditions.
The author uses all available archival materials from the funds of the National Archives of the Republic of Moldova, memoirs
of the artists of the ensemble, reminiscences of eyewitnesses, biographies of the artistic directors of the ensemble
Facultatea Urbanism şi Arhitectură: Tramvaiul tras de cai
No full textLa Catedra „Design interior” (şef – dl Alexandru Cocin, conf., dr.) specialitatea „Sculptură” a fost executată o lucrare de diplomă mai puţin obişnuită. Absolvenţii Alexandru Coicev, Marcel Botnaru, Doina Coval şi Sergiu Racu, sub conducerea dlui Oleg Dobrovolschi, lector superior, ajutaţi şi de dl Petru Postolache, maistru-sculptură, au readus în memoria noastră renumitul tramvai tras de cai, care circula în Chişinău pe strada centrală Alexandru cel Bun (astăzi – bulevardul Ştefan cel Mare şi Sfânt) în anii ’30-’40 ai secolului trecut
Probleme actuale în dermatovenerologie, pneumoftiziologie, radiologie și imagistică
No full textModeratori: Iavorschi Constantin, dr. hab. şt. med., profesor universitar
Beţiu Mircea, dr. şt. med., conferenţiar universitar
Rotaru Natalia, dr. hab. şt. med., profesor universitar
Rusu Dona, dr. şt. med., conferenţiar universitar
Ustian Aurelia, dr. şt. med., profesor consultant
Gogu Vladislav, dr. şt. med., conferenţiar universitarCOMUNICĂRI ORALE
1. Abaev Rozalina. Efectele adverse ale tratamentului tuberculozei multidrog
rezistente
2. Chesov Dumitru, Muntenau Oxana, Rusu Doina, Cozlovschi Victor,
Semionică Iurie, Botnaru Victor. Rolul specimenelor de aspirat bronșic în
diagnosticul tuberculozei pulmonare
3. Cotelea Eugeniu, Lesnic Evelina. Factorii de risc de îmbolnăvire de tuberculoză la pacienții cu alcoolism cronic
4. Emeț Iulia, Bețiu Mircea, Сhiriac Anca. Alopeciile primar cicatriciale:
aspctele clinice, dermatoscopice și histopatologice
5. Munteanu Oxana, Rusu Doina, Țâmbală Diana, Botnaru Victor. Bronșiectaziile la pacienții adulți cu infecție HIV/SIDA: serie de cazuri
6. Nedelciuc Boris. Profilul resurselor umane în domeniul serviciilor de cosmetology
7. Tertîșnîi Ludmila. Traumatismul osteoarticular – algoritm imagistic cu aspecte
medico-legale
8. Ungureanu-Chirvas Elena. Neurofibromatoza tipul I (clasică von Recklinghausen) – reflecții pe marginea unui caz clasi
Phenotypic approach of treatment in rosacea
No full textDepartment of Dermatovenereology, Nicolae Testemitanu State University of
Medicine and Pharmacy, Chisinau, Republic of Moldova, The 8th International Medical Congress for Students and Young Doctors, September 24-26, 2020Introduction. Rosacea is a chronic inflammatory disorder. The prevalence of rosacea is highest
among fair-skinned individuals, and according to some studies constitutes up to 10% of the
adult population. Although it is a common dermatologic condition, rosacea is shockingly
overlooked. The aetiology, pathogenesis, the clinical manifestasions and management of
rosacea still remain disputed. The classic treatment, based on classification of rosacea in 3
successive clinico-evolutive forms (erythematous-telangiectatic, papulo-pustular and
phimatosa) remains weak resulting for some patients.
Aim of the study. Development of an individualized treatment based on clinical assessment
of phenotypic expressions in rosacea.
Materials and methods. Published literature of the last 5 years, involving the therapeutic
behaviour in rosacea, was examined and summarized.
Results. Rosacea is a common cutaneous condition that is frequently overlooked. As a result
of its multifactorial nature and characteristic relapsis and remisions, diagnosis is complex.
Although rosacea is known to be an angio-neurosis, the types of skin haemodynamic disorders
that are likely to induce different clinical manifestations of the disease have not been
appreciated yet. In this study, was analyzed the therapeutic action of topical and systemic drugs
used in rosacea and their efficacy according to the phenotypic expression of the disease. Were
appreciated the therapeutic effects of topical drugs such as: Brimonidine, Oxymetazoline,
Ivermectin, Metronidazole and Azelaic Acid , as well as systemic therapies with Azithromycin,
Doxycycline, Propranolol, Sulodexid and Isotretinoin, for each phenotypic lesion separately.
As a result, were determined the drogs that had the highest clinical efficacy for the control of
erythema, telangiectasias, papules, pustules, granulomatous or phymatous-lesions of rosacea.
Topically applied Brimonidine and Oxymetazoline have been shown to be more effective for
controlling erythematous flushes than Metronidazole or Azelaic Acid. Ivermectin had good
results in the control of papules and pustules for uncomplicated rosacea forms.Systemic therapy
with Propranolol has good clinical efficacy and better result than Doxycycline in the control of erythema and telangiectasias in patients with erythematous-telangiectatic and papulo-pustular
rosacea. The phimosis monitoring in rosacea can be performed by systemic administration of
Isotretinoin.
Conclusions. 1.Clinicians are encouraged to determine the lesion phenotype in patients with
rosacea and to select a optimal individualized treatment. 2. The treatment of skin hemodynamic
disorders in rosacea with vasoactive therapies with beta-blockers, antithrombotics and
flavones, has a curative potential that should be studied
An Econometric model for the evolution of the Romanian Interbank Bid Rate (ROBID) in the context of the international financial crisis
No full textThe paper presents the econometric modeling of overnight inter-banking interest rates (ROBID) in our country, the analyzed period is between 1999-2010. The international financial crises had a great impact on the level of inter-banking interest rates after 2007 and it reflects the new level of risk for the Romanian system banking. The econometric model used in modeling the interest rates is an autoregressive moving average (ARMA) model, the ARMA model is typically applied to time series data; the paper propose several ARMA models, applies econometric tests and based on them the analyzed series (the inter-banking interest rates) forecast will be made.ROBID, ARIMA model, financial crisis, forecast.
Pneumonia comunitară la adult: protocol clinic naţional PCN-3
No full textAcest protocol a fost elaborat de grupul de lucru al Ministerului Sănătăţii al Republicii Moldova
(MSRM), constituit din specialiştii Disciplinei Pneumologie și Alergologie a Universităţii de
Stat de Medicină şi Farmacie „Nicolae Testemiţanu”.
Protocolul naţional este elaborat în conformitate cu ghidurile internaţionale actuale privind
pneumonia comunitară la persoanele adulte şi va servi drept bază pentru elaborarea
protocoalelor instituţionale (extras din protocolul naţional aferent pentru instituţia dată, fără
schimbarea structurii, numerotaţiei capitolelor, tabelelor, figurilor, casetelor etc.), în baza
posibilităţilor reale ale fiecărei instituţii în anul curent. La recomandarea MS pentru
monitorizarea protocoalelor instituţionale pot fi folosite formulare suplimentare, care nu sunt
incluse în protocolul clinic naţional
Natural language processing : semantic aspects / by Epaminondas Kapetanios, Doina Tatar, Christian Sacarea.
No full textcomputer bookfair20151 volume
Легочные бактериальные ко-инфекции и антибактериальная резистентность при SARS-COV-2: роковая коалиция будущего пост-COVID-19
No full textBackground. A third wave of COVID-19 infection is now sweeping across the globe. Severe injury of the epithelial barrier, caused by the action of respiratory viruses (including coronaviruses), facilitates the invasion of the respiratory tract with other germs, like viruses, fungy or bscteria. Methods. 92 inpatients with COVID-19 pneumonia and 68 inpatients with nosocomial pneumonia (NP) non COVID-19 were enrolled in our study. For microbiological assessment sputum samples were collected. Statistical analysis performed using the x2 test (Statistica software, version 7.0). Results. From the 92 COVID-19 patients 64 (69,2%) were dignosed with secondary nosocomial bacterial infection (SNBI). Overall ESKAPE agents, like K.pneumoniae, E.faecium, Acinetobacter spp. and Ps.aeruginosa were highly detected in SARS- CoV-2 group — 85,7%. in opposed to non COVID-19 group, bacterial agents isolated from the patients with SARS-CoV-2 SNBI manifested higher rate of antibiotical panresistance (p < 0,05). Conclusions. The study showed some etiological and antibiotic resistance differences of COVID-19 SNBI, compared to non SARS-CoV-2 NP and a higher rate of antibiotical panresistance in COVID-19 group. Thus, the empirical treatment in bacterial co-infections in SARS-CoV-2 patients requires proven argumentation and adjustment to antibiotic resistance data in each case separatelyIntroducere. Pandemia globală cauzată de SARS-CoV-2 este în plina desfăşurare, mai multe ţări raportând un al treilea val de infecţie. Injuria severă a barierei epiteliale, provocată de acţiunea viruşilor respiratori (inclusiv coronaviruşi), facilitează invazia tractului respirator cu alţi germeni — virali, fungici sau bacterieni. Materiale şi metode. În studiu au fost incluşi 92 pacienţi internaţi cu pneumonie COVID-19 şi 68 cazuri de pneumonie nosocomială (PN) non COVID-19. Pentru analiza bacteriologică au fost colectate secreţiile bronşice (expectoraţii libere, aspiratul transtraheal, lavajul bronhoalveolar — LBA). Compararea diferenţelor dintre variabilele loturilor analizate cu diferite valori a fost efectuată utilizând testul x2 sau testul exact al lui Fisher, utilizând softul Statistica 7.0. Rezultate. Din lotul de 92 pacienţi internaţi cu SARS-CoV-2 69,5% (64/92) pacienţi au fost eligibili pentru criteriul de infecţie bacteriană secundară (IBS) pulmonară intraspitalicească. În total au fost analizate 84 culturi bacteriene, dintre care germenilor din grupul ESKAPE le-a revenit o pondere mai mare — 72 tulpini (85,7%). Cel mai des au fost izolaţi K.pneumoniae, E.faecium, Acinetobacter spp. şi Ps.aeruginosa. În lotul COVID-19 panrezistenţa microbiană a fost semnificativ mai frecvent întâlnită (p < 0,05) faţă de lotul PN. Concluzii. Studiul a evidenţiat unele diferenţe etiologice şi de antibiorezistenţă ale infecţiilor bacteriene secundare pulmonare în SARS-CoV-2, comparativ cu pneumoniile nosocomiale non COVID-19. În grupul pacienţilor cu IBS SARS-CoV-2 ponderea agenţilor patogeni pandrogrezistenţi este mai mare comparativ cu PN. Astfel, iniţierea tratamentului antibacterian empiric în co-infecţiile pulmonare la pacienţii cu SARS-CoV-2 necesită o argumentare demonstrată, iar schemele de tratament necesită ajustare imediată la obţinerea datelor despre antibioticorezistenţă în fiecare caz separatРезюме. Легочные бактериальные ко-инфекции и антибактериальная резистентность при sars-cov-2: роковая коалиция будущего пост-COVID-19 Введение. На сегодняшний день многие страны переживают пик третьей волны глобальной пандемии SARS- CoV-2. Нарушение целостности эпителиального барьера, вызванное действием респираторных вирусов (в том числе и коронавирусов), способствует присоединению вторичной инфекции — вирусной, грибковой или бактериальной. Материалы и методы. В ходе исследования мы проанализировали 92 случая пневмоний, вызванных COVID-19, и 68 случаев нозокомиальных пневмоний (НП) non-COVID-19. Мы провели бактериологический анализ мокроты, а также оценили чувствительность микроорганизмов к антибактериальным препаратам. Статистический анализ был проведен при помощи программы Statistica 7.0. Результаты. Вторичная внутрибольничная бактериальная инфекция легких (ВВБИЛ) была диагносцированна у 69,5% (64/92) пациентов с SARS-CoV-2. Из 84 бактериальных культур, выделенных у пациентов с COVID-19, 72 колонии (85,7%) принадлежали группе возбудителей ESKAPE: K.pneumoniae, E.faecium, Acinetobacter spp. и Ps.aeruginosa. Панрезистентность микроорганизмов к антибактериальным препаратам в этой группе пациентов была значительно выше, чем в группе пациентов nonCOVID-19 (p < 0,05). Выводы. В ходе нашего исследования были выявлены определенные этиологические отличия и разная степень бактериальной чувствительности к антибиотикам при ВВБИЛ у пациентов с SARS-CoV-2 по сравнению с НП non-COVID-19. При этом, и панрезистентность микроорганизмов к антибактериальным препаратам в этой группе пациентов была значительно выше. Таким образом, назначение эмпирического бактериального лечения при ВВБИЛ при инфекции SARS-CoV-2 должно быть аргументированным и строго соответствовать результатам бактериальной чувствительности к антибиотикам в каждом отдельном случа
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