39 research outputs found
Transglutaminase Type 2 is Involved in the Hematopoietic Stem Cells Homeostasis
No full textType 2 transglutaminase (TG2) is a multifunctional protein involved in various biological processes playing a key regulatory role in cell homeostasis such as cell death and autophagy. New evidence is emerging that support an important role of autophagy in regulating normal hematopoiesis. Prompted by these findings, in this study we investigated in vivo involvement of TG2 in mouse hematopoiesis under normal or nutrient deprivation conditions. We found that the number and rate of differentiation of bone marrow hematopoietic stem cell was decreased in the TG2 knockout mice. We present evidence showing that these effects on hematopoietic system are very likely due to the TG2-dependent impairment of autophagy. In fact, stimulation of autophagy by starvation is able to rescue the block of the differentiation of stem cells progenitors in the TG2 KO mice. It was also shown that the RhoA/ERK1/2 pathway, known to be essential for regulation of the bone marrow progenitor cells homeostasis, was significantly impaired in the absence of TG2. Hence, this study expanded our knowledge about TG2 discovering a role of this enzyme in regulation of hematopoiesis
Recurrent arterial embolization from a metastatic carcinoma of unknown primary site [4]
No full text[No abstract available]BLOCH RS, 1986, J CARDIOVASC SURG, V27, P630; GUYTON DP, 1987, J SURG ONCOL, V36, P183, DOI 10.1002-jso.2930360307; Morsey H, 2004, INT ANGIOL, V23, P82; Tsuji T, 2001, Nihon Kokyuki Gakkai Zasshi, V39, P6150
Du dessin au dessein des plantes sauvages
No full textInternational audienceRecounting his ethnobotanical survey carried out with the Kasua society (PNG), the author illustrates the role that J. Barrau gave to botanical drawing as an ethnographic tool for apprehending the living world but also the place of man in the living world. Keywords: botanical drawing, ethnographic tool, uses of flora, interactive logics, plant personality.Relatant son enquête ethnobotanique menée auprès de la société kasua (PNG), l'auteur illustre le rôle que prêtait J. Barrau au dessin botanique comme outil ethnographique pour appréhender le monde vivant mais aussi la place de l'homme dans le monde vivant. Mots-clés : dessin botanique, outil ethnographique, usages de la flore, logiques interactives, personnalité végétale
Eléments pour une étude des représentations de la canne à sucre chez les Ankave-Anga (PNG)
No full textNational audienceIn the set of representations the Ankave have elaborated concerning food and nurturing, sugar cane seems unambiguously associated with maternal milk. Yet, the ways sugar cane is consumed during male initiations point to a more complex situation, which the author analyzes in this particular ethnographic context as well as with respect to what is known of the connections other Angans make between bodily substances and several foods.Dans l'ensemble des représentations qu'ont les Ankave des aliments, la canne à sucre est associée sans ambiguïté aucune au lait maternel, du moins à première vue. Car les modalités de consommation de celle-ci lors des rituels masculins révèlent une situation plus complexe, que l'auteur analyse à la fois dans le contexte ethnographique concerné et à l'aune de ce que l'on sait des associations entre les substances corporelles et certains aliments dans d'autres groupes anga
Tension in the Natural History of Human Thinking
No full textMichael Tomasello has greatly expanded our knowledge of human cognition and how it differs from that of other animals. In this commentary to his recent book A Natural History of Human Thinking, I first critique some of the presuppositions and arguments of his evolutionary story about how homo sapiens’ cognition emerged. For example, I question the strategy of relying on the modern chimpanzee as a model for our last shared ancestor, and I doubt the idea that what changed first over evolutionary time was hominin behavior, which then in turn brought about changes in cognition. In the second half of the commentary I aim to show that the author oscillates between an additive and a transformative account of human shared intentionality. I argue that shared intentionality shapes cognition in its entirety and therefore precludes the possibility that humans have the same, individual intentionality (as shown in, e.g. their instrumental reasoning) as other apes
Molophilus (Molophilus) pleuralis
No full textMolophilus (Molophilus) pleuralis de Meijere, 1920 Figures 24, 25 Molophilus pleuralis de Meijere, 1920: 60 (description), Pl. 4, Figs 53 a–b (male terminalia). Type material examined. The species was described from an unspecified number of specimens from “Amsterdam, Diemen, Haarlem, Abcoude, Hilversum, Uitgeest, Leimuiden, Zwammerdam” (de Meijere 1920: 60). Altogether 32 syntypes (25 3, 5 Ƥ, 2 specimens without abdomen) are now deposited in ZMAN, and one male syntype in ZMHB (de Jong 2000: 170–171). I have examined four male syntypes from ZMAN, all belonging to M. (M.) pleuralis, including one labelled (but not published) as lectotype by Br. Theowald. The latter is here designated accordingly. Lectotype 3 (by present designation): Netherlands, Amsterdam, 11.v. 1919 (J.C.H. de Meijere leg.) (ZMAN), labelled “Amsterdam / 11.V. 19 / de Meijere” (partly printed, date handwritten), a paper square with “C”, “ Lectotype / M. pleuralis / n. sp. / des. Theow.” (handwritten, red), “ Molophilus / pleuralis / de Meijere, 1920 / ZMAN type DIPT.0671.22” (printed, red). Labelled as lectotype by the present author (“ LECTOTYPE / Molophilus / pleuralis de Meijere 3 / J. Starý 2010 ”; printed red label). The specimen is micro-pinned on a piece of foam, with only left fore and mid legs attached; apex of abdomen cut off. Terminalia mounted by de Meijere in Canada balsam on a celluloid slide, pinned with the specimen. Paralectotypes: Netherlands: Diemen, 3.viii. 1918, 1 3; Uitgeest, 1.viii. 1918, 1 3; Haarlem, ± 18.viii. 1919, 1 3 (all J.C.H. de Meijere leg.) (all ZMAN). All specimens have red paratype labels and labels with numbers “0671.17”, “0671.12”, and “0671.25”, respectively. All specimens subsequently labelled as paralectotypes by the present author. The lectotype is designated here to stabilize the concept of the name with respect to M. (M.) brevifurcatus sp. n. Other material examined (9 3, 1 Ƥ): Greece: Pieria Region: Eginio env., Aliakmonas delta, cut-off meander, 4.vi. 2007, 1 3 (J. Starý leg.) (JSO). Crete: Khania Region: Kavros, 19.v. 2004, 1 3 (J. Roháček & M. Vála leg.); Kavros, marsh, 20.v. 2004, 6 3, 1 Ƥ; Kavros, 24.v. 2004, 1 3 (both J. Starý leg.) (all JSO). Distribution. Widely distributed in the Palaearctic: Europe, including Cyprus; Turkey, Transcaucasia, Israel, Iran, Middle Asia, Russia as far as Far East. First records for Greece (incl. Crete).Published as part of Starý, Jaroslav, 2011, Descriptions and records of the Palaearctic Molophilus Curtis (Diptera, Limoniidae), pp. 45-62 in Zootaxa 2999 on pages 55-56, DOI: 10.5281/zenodo.20328
Catheter fracture and migration into the coronary sinus-an unusual migration site: case report and review
No full textCatheter fracture and cardiac migration are rare but known complications. Most reported cases have developed between the clavicle and the first rib as a consequence of catheter pinching between these two bony structures. To our knowledge, this is the first reported case of catheter migration into the coronary sinus. The broken fragment was successfully retrieved using loop-snare technique. © 2009 Elsevier Inc. All rights reserved.AITKEN DR, 1984, AM J SURG, V148, P633, DOI 10.1016-0002-9610(84)90340-4; ANDRIS DA, 1994, JPEN-PARENTER ENTER, V18, P531, DOI 10.1177-0148607194018006531; CASSIDY FP, 1988, AM J ROENTGENOL, V150, P696; Chang Chia-Lo, 2005, Chang Gung Med J, V28, P425; Coles C E, 1998, Clin Oncol (R Coll Radiol), V10, P412, DOI 10.1016-S0936-6555(98)80047-2; CURRY JL, 1969, AMER J ROENTGENOL RA, V105, P894; EDWARDS AC, 1978, BRIT MED J, V2, P669; FISHER RG, 1978, AM J ROENTGENOL, V130, P541; HALL P, 1989, J SURG ONCOL, V41, P39, DOI 10.1002-jso.2930410112; HUANG TY, 1984, AM FAM PHYSICIAN, V30, P177; KIRVELA O, 1989, JPEN-PARENTER ENTER, V13, P99, DOI 10.1177-014860718901300199; Klotz HP, 1996, J SURG ONCOL, V62, P222, DOI 10.1002-(SICI)1096-9098(199607)62:3222::AID-JSO143.0.CO;2-8; Kock HJ, 1998, WORLD J SURG, V22, P12; LAFRENIERE R, 1991, J SURG ONCOL, V47, P261, DOI 10.1002-jso.2930470411; LOKICH JJ, 1985, J CLIN ONCOL, V3, P710; Nace C S, 1993, Oncol Nurs Forum, V20, P1227; O'Cochlain B, 2001, PACE, V24, P1284, DOI 10.1046-j.1460-9592.2001.01284.x; Polderman KH, 2002, INTENS CARE MED, V28, P1, DOI 10.1007-s00134-001-1154-9; Sattari Maryam, 2003, Interact Cardiovasc Thorac Surg, V2, P532, DOI 10.1016-S1569-9293(03)00137-3; Suarez-Penaranda JM, 2000, J FORENSIC SCI, V45, P92055
Pemanfaatan Web Service Moodle Berbasis Rest-Json Untuk Intensitas Pengguna E-Learning
No full textAbstract : E-learning is one of the needs of school and university institutions. At SMK PGRI Tanjung Raja wants access to online learning (E-learning) to make it easier for teachers to distribute learning materials to students. The author will develop Moodle e-learning as a web service that can be used. To help monitor the activities carried out by the teacher, the author will use rest-json as a data collection format and will display a report format for the recapitulation of teacher activeness in online learning. The results of this study are that Moodle can be used by 3 users, namely admin as manager, teacher and students as general users, to see the results of the teacher\u27s point report can be seen on the teacher\u27s income menu.
Keywords: : E-Learning, Moodle, Web Service, Waterfall, Rest-Json
Abstrak : E-learning menjadi salah satu kebutuhan dari institusi sekolah maupun perguruan tinggi. Pada SMK PGRI Tanjung Raja menginginkan adanya akses pembelajaran online (E-learning) untuk mempermudah guru dalam membagikan materi pembelajaran kepada siswa/siswi. Penulis akan mengembangkan E-learning moodle sebagai web service yang dapat digunakan. Untuk membantu pemantauan aktivitas yang dilakukan oleh guru, penulis akan memanfaatkan rest-json sebagai format pengambilan data dan akan menampilkan format laporan rekapitulasi keaktifan guru dalam pembelajaran secara online. Hasil dari penelitian ini yaitu moodle dapat digunakan oleh 3 pengguna yaitu admin sebagai pengelola, guru dan siswa sebagai pengguna umum, untuk melihat hasil laporan poin guru dapat dilihat pada menu income guru.
Kata kunci: E-Learning, Moodle, Web Service, Waterfall, Rest-Jso
Gérer le passé pour façonner l’avenir à Wëté et Drueulu
No full textThis article proposes an interlacing of the ethnographic experiences of two researchers working in two different field sites, one in the north of the Grande Terre (Wëté), the other in Lifou (Drueulu), with the aim of better understanding how, in this pre-referendum historic moment, Kanak men and women refer to their own past and redefine it. Each author presents his/her respective analysis, which results from this dialogue. The text highlights an increased desire on the part of the Kanak people to be protagonists in redeploying and valorizing elements of their own societies in the face of the challenges of the future. The historic moment of the 2018 referendum is not only unfolding around political issues, it also entails a vision that makes the idea of a sustainable society rooted in Kanak cultural elements a central concern
The Serum Levels of Endothelium Nitric Oxide Synthase in Positive Cases for Helicobacter pylori Stool Antigen
No full textBackground & Objectives: Endothelium nitric oxide synthase (eNOS) is a type of enzyme
which produces an endogenous factor called nitric oxide (NO). NO plays important role in
progress of euplastic diseases. In chronic gastritis, the increased level of NO causes damages
to DNA. The aim of present study is to evaluate eNOS concentration in sera of healthy people
and those infected by Helicobacter pylori.
Methods: The sera and stool specimens from 84 voluntaries (Female: 58.3%, Males 41.6%)
were collected. Helicobacter pylori antigen in the stool specimens and eNOS levels in sera
were determined using ELISA. Obtained data were analyzed using Excell software.
Results: The age range was from 1 to 78 years old (Mean: 30 years old). In terms of special
diseases, 70.2% did not have any special diseases, but 29.76% showed at least one special
disease, mainly thyroid disease and hypertension. The results for H. pylori stool antigen
detection showed that 16.6%, 29.76% and 53.57% of collected specimens were equivocal,
Helicobacter pylori negative and positive respectively. Comparison of sera concentrations of
eNOS showed that there is no significant change among these three groups.
Conclusion: As mentioned in results, the eNOS sera concentrations showed no significant
change in Helicobacter pylori positive and negative groups. Albeit the other studies showed
the significant increase in serum concentration of Helicobacter pylori positive patient, this
controversy may arise from race and variations in Helicobacter pylori pathogenic islands such
as those containing VacA and CagA. We propose to conduct a similar study in Ardabil to
focus on the pathogenic islands of H. pylori strains in this province
