7,011 research outputs found

    Weighing Evidence from Mendelian Randomization-Early-Life Obesity as a Causal Factor in Multiple Sclerosis?

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    In this Perspective, Alberto Ascherio and Kassandra Munger discuss the implications of Richards and colleagues' study exploring the role of early-life obesity in risk of multiple sclerosis

    [Poesia] Três poemas de Alberto Secama

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    Three poems by Alberto Secama. About the author: Alberto Secama is an Angolan poet who has poems published on many websites and on facebook:https://www.facebook.com/Xungurra/abouthttp://www.pordentrodaafrica.com/cultura/africa-em-verso-rio-kwanza-por-alberto-secamahttp://www.pordentrodaafrica.com/cultura/africa-em-verso-zong-por-alberto-secamahttp://www.pordentrodaafrica.com/cultura/coluna-africa-em-verso-o-sol-la-fora-por-alberto-secamaTres poemas de Alberto Secama. Sobre el autor: Alberto Secama es un poeta angoleño que tiene poemas publicados en varios sitios y en el facebook:https://www.facebook.com/Xungurra/abouthttp://www.pordentrodaafrica.com/cultura/africa-em-verso-rio-kwanza-por-alberto-secamahttp://www.pordentrodaafrica.com/cultura/africa-em-verso-zong-por-alberto-secamahttp://www.pordentrodaafrica.com/cultura/coluna-africa-em-verso-o-sol-la-fora-por-alberto-secamaTrês poemas de Alberto Secama. Sobre o autor: Alberto Secama é um poeta angolano que possui poemas publicados em vários sites e no facebook:https://www.facebook.com/Xungurra/abouthttp://www.pordentrodaafrica.com/cultura/africa-em-verso-rio-kwanza-por-alberto-secamahttp://www.pordentrodaafrica.com/cultura/africa-em-verso-zong-por-alberto-secamahttp://www.pordentrodaafrica.com/cultura/coluna-africa-em-verso-o-sol-la-fora-por-alberto-secam

    sj-docx-1-msj-10.1177_13524585231208310 – Supplemental material for Smoking during pregnancy and risk of multiple sclerosis in offspring and mother: A Danish nationwide register-based cohort study

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    Supplemental material, sj-docx-1-msj-10.1177_13524585231208310 for Smoking during pregnancy and risk of multiple sclerosis in offspring and mother: A Danish nationwide register-based cohort study by Nete Munk Nielsen, Morten Frisch, Sanne Gørtz, Egon Stenager, Kristin Skogstrand, David M Hougaard, Alberto Ascherio, Klaus Rostgaard and Henrik Hjalgrim in Multiple Sclerosis Journal</p

    Orizzonti mantovani. Spunti e dinamiche paesaggistiche ne L'Illustrissimo di Alberto Cantoni

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    In the literary production of Alberto Cantoni, short story writer and novelist between the nineteenth and twentieth centuries, the novel L'Illustrissimo is highly important both because it is the last publication of the author, from Pomponesco, a small town a few kilometers south of Mantua, both because it summarizes in a single text the different nuances and different directions that his writing has taken over the course of his literary career, also due to a writing and processing time that embraces the entire span of years of his career itself. In the foreground, in addition to the numerous and brilliant characters, one of the protagonists is the Mantuan landscape which, not a simple background, becomes a true literary parameter which in different and significant ways affects the purposes and mechanisms of the novel

    Variations in the Gender Ratio of Multiple Sclerosis Linked to Converging Smoking Trends in Men and Women

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    [S40.001] Variations in the Gender Ratio of Multiple Sclerosis Linked to Converging Smoking Trends in Men and WomenNatalia Palacios, Boston, MA, Alvaro Alonso, Minneapolis, MN, Henrik Bronnum-Hansen, Coppenhagen, Denmark, Alberto Ascherio, Boston, MA OBJECTIVE: To examine if a time-dependent relationship exists between changing female-to male ratios of smoking and Multiple Sclerosis (MS) in worldwide birth cohorts from previously published studies. BACKGROUND: Smoking behavior in industrialized nations has changed dramatically over the second half of the 20th century, with diverging patterns in male and female smoking rates. During the same time period, an increase in the female to male ratio in MS incidence has been reported. We examined whether MS incidence in the two genders changed concomitantly with smoking, as would be expected if smoking truly increased MS risk. DESIGN/METHODS: We identified relevant studies reporting male and female age-specific incidence of MS throughout the world using within-country birth cohorts as units of observation. For each country and birth cohort, we then estimated the male to female ratio in MS incidence, and correlated these ratios with the corresponding male to female ratios in smoking behavior obtained from national statistics. In addition, in separate analyses we also examined in depth the within-country trends of smoking and MS for two populations in which statistics on MS are readily available: Canada and Denmark. RESULTS: We show that the gender ratio of MS is correlated with the gender ratio of smoking (r = 0.12, 95% CI: 0.02, 0.22; p = 0.02). This correlation supports an overall incidence rate ratio of 1.40 (95% CI: 1.02, 1.89) of MS for ever smokers as compared with never smokers. Furthermore, our within-country analyses of smoking and MS trends in Canada and Denmark show that, depending on model assumptions, smoking could explain 20 to 89% of the change in the female to male ratios of MS. CONCLUSIONS/RELEVANCE: Our results are consistent with the hypothesis that smoking increases the risk of MS. Smoking trends might partially explain changes in the MS gender ratio. Supported by: Dr. Ascherio: funding for studies of MS from NIH/NINDS. Natalia Palacios: Training Program in Environmental Epidemiology funded under grant no. T32 ES07069. The Danish Multiple Sclerosis Society finances the Danish Multiple Sclerosis Registry.Category - MS and Related Diseases - Clinical ScienceWednesday, April 14, 2010 4:15 PMScientific Sessions: Multiple Sclerosis: Epidemiology (4:15 PM-5:30 PM)</strong

    Variations in the Gender Ratio of Multiple Sclerosis Linked to Converging Smoking Trends in Men and Women

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    [S40.001] Variations in the Gender Ratio of Multiple Sclerosis Linked to Converging Smoking Trends in Men and WomenNatalia Palacios, Boston, MA, Alvaro Alonso, Minneapolis, MN, Henrik Bronnum-Hansen, Coppenhagen, Denmark, Alberto Ascherio, Boston, MA OBJECTIVE: To examine if a time-dependent relationship exists between changing female-to male ratios of smoking and Multiple Sclerosis (MS) in worldwide birth cohorts from previously published studies. BACKGROUND: Smoking behavior in industrialized nations has changed dramatically over the second half of the 20th century, with diverging patterns in male and female smoking rates. During the same time period, an increase in the female to male ratio in MS incidence has been reported. We examined whether MS incidence in the two genders changed concomitantly with smoking, as would be expected if smoking truly increased MS risk. DESIGN/METHODS: We identified relevant studies reporting male and female age-specific incidence of MS throughout the world using within-country birth cohorts as units of observation. For each country and birth cohort, we then estimated the male to female ratio in MS incidence, and correlated these ratios with the corresponding male to female ratios in smoking behavior obtained from national statistics. In addition, in separate analyses we also examined in depth the within-country trends of smoking and MS for two populations in which statistics on MS are readily available: Canada and Denmark. RESULTS: We show that the gender ratio of MS is correlated with the gender ratio of smoking (r = 0.12, 95% CI: 0.02, 0.22; p = 0.02). This correlation supports an overall incidence rate ratio of 1.40 (95% CI: 1.02, 1.89) of MS for ever smokers as compared with never smokers. Furthermore, our within-country analyses of smoking and MS trends in Canada and Denmark show that, depending on model assumptions, smoking could explain 20 to 89% of the change in the female to male ratios of MS. CONCLUSIONS/RELEVANCE: Our results are consistent with the hypothesis that smoking increases the risk of MS. Smoking trends might partially explain changes in the MS gender ratio. Supported by: Dr. Ascherio: funding for studies of MS from NIH/NINDS. Natalia Palacios: Training Program in Environmental Epidemiology funded under grant no. T32 ES07069. The Danish Multiple Sclerosis Society finances the Danish Multiple Sclerosis Registry.Category - MS and Related Diseases - Clinical ScienceWednesday, April 14, 2010 4:15 PMScientific Sessions: Multiple Sclerosis: Epidemiology (4:15 PM-5:30 PM)</strong

    Plenary Session: Luis Alberto Urrea

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    a) Plenary Session: Luis Alberto Urrea, Mexican American Chicago Writer Luis Alberto Urrea is a 2005 Pulitzer Prize finalist for non-fiction and member of the Latino Literature Hall of Fame. He is a prolific and acclaimed writer who has used his dual-culture life border experiences to explore the complex and interconnected Mexican-US American reality. The critically acclaimed and best-selling Mexican-born author of 13 books, Urrea has won numerous awards for his poetry, fiction and essays. Moderator: Dr. Héctor García, Loyola University Chicag

    O duplo significado do sentir e do pensar nas obras de Alberto Caeiro e Descartes

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    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Programa de Pós-Graduação em LiteraturaA pretensão desta dissertação intitulada O duplo significado do sentir e do pensar nas obras de Alberto Caeiro e Descartes é investigar a relação entre o sentir e o puro pensar, usando como referência a poesia O Guardador de Rebanhos, de Alberto Caeiro, que apresenta de forma evidente o tema; e como este assunto é tratado nas Meditações Metafísicas de René Descartes, também de forma claramente visível. Podemos perceber em ambos os autores, uma diplopia, uma espécie de duplo olhar sobre a relação sentir e puro pensar. No primeiro capítulo vou falar sobre a tese do duplo olhar de Descartes, a respeito da relação sentir e puro pensar na leitura de Merleau-Ponty, salientando a visão de natureza. No segundo capítulo, parto da leitura das três primeiras Meditações Metafísicas para caracterizar a tensão que se pode verificar entre Descartes e Alberto Caeiro quando se referem ao puro pensar. O foco principal de Descartes, nas três primeiras Meditações, é o pensar puro, e neste ponto Alberto Caeiro critica o pensar puro. No terceiro capítulo, analisando as três últimas Meditações, percebe-se que há uma virada no pensamento de Descartes, no qual o autor inverte seu ponto de vista, aproximando-se da idéia de Alberto Caeiro. No quarto capítulo, mostrarei a leitura que outros autores fazem acerca do sentir e do pensar na obra de Alberto Caeiro, mostrando que assim como Descartes, este também ostenta uma diplopia, não do sentir, mas do pensar. The pretension of this work entitled O duplo significado do sentir e do pensar nas obras de Alberto Caeiro e Descartes is to investigate the relationship between the feeling and the pure thinking, using as reference the poetry O Guardador de Rebanhos, by Alberto Caeiro, that presents in an evident way this theme; and as this subject is treated in René Descartes' Metaphysical Meditations, also in a clearly visible way. It is possible to notice in both authors, the diplopy, a sort of double look about the relationship between feeling and pure thinking. The thesis about Descartes'double look regarding the relation of feeling and pure thinking, in Merleau-Ponty reading, pointing out the nature vision, will be treated in the first chapter. In the second chapter, I start from the reading of the first three Metaphysical Meditations to characterize the tension that can be verified between Descartes and Alberto Caeiro when they refer to the pure thinking. Descartes' main focus in the first three Meditations is pure thinking and, in this point, Alberto Caeiro criticizes pure thinking. In the third chapter, analyzing the last three Meditations, it is possible to notice that there is an alteration in Descartes' thought, in which the author inverts his point of view, approaching of Alberto Caeiro's idea. In the fourth chapter, I will show the reading that other authors do concerning feeling and thinking in Alberto Caeiro's work, showing that as well as Descartes, this also shows a diplopy, not of feeling, but of thinking

    Lobbying for change as a new theory and practice of active citizenship: author interview with Alberto Alemanno

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    Do you believe that lobbying is a vehicle for representing the interests of some rather than all, meaning its actors can never be a force for good? Alberto Alemanno, author of Lobbying for Change: Find Your Voice to Create a Better Society, might convince you of the contrary. This interview with Barbara Aubin, LSE Public Affairs, reflects on the importance of engaging with our political representatives, holding them accountable and lobbying for the causes we deeply care about as fundamental elements of a healthy democracy

    Bibliografia di Umberto Romagnoli

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    A complete bibliography of Umberto Romagnoli writings, introduced by a few lines by editors of the Journal and completed by an essay by Alberto Mattei dealing with some technical aspects of the collection of the bibliography interwoven with some scholarly life moments of the author
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