40 research outputs found
Kosztolányi színpadi művei: Tanulmányok
No full textDOBOS ISTVÁN: Színmű és regény viszonya Kosztolányi életművében;
TAKÁCS LÁSZLÓ: Odüsszeusz útja: Adalékok Kosztolányi mesejátékának keletkezéstörténetéhez;
SZILÁGYI ZSÓFIA: „A közönség semmit sem vesz észre”: (Patália);
BENGI LÁSZLÓ: Párbeszéd és mérték;
GYŐREI ZSOLT: Rímjáték a novelláskötetben: a Csoda a műnemek hármasútján;
DOBÁS KATA: Néhány kérdés Kosztolányi Dezső Kanári című darabjával kapcsolatban;
PINTÉR BORBÁLA: Mi a színpad? Kosztolányi Dezső Dialóg című verses jelenetéről;
PARÁDI ANDREA: „Az igazi varázsló”: A bábjátékos keletkezéstörténetéről;
ZÁKÁNY TÓTH PÉTER: Szakralizáció és de(és/vagy re)szakralizáció: Kosztolányi Dezső: Lucifer a katedrán;
BUCSICS KATALIN: Kosztolányi Dezső: A kékruhás: A fiatal Kosztolányi Reviczky-képéhez;
HUTVÁGNER ÉVA: „egy lyukas lavór védelme alatt”: Kosztolányi Dezső: A lovag meg a kegyence versus Kosztolányi Dezső A lovag meg a kegyese;
VARGA KINGA: Leszármazások: Az Édes Anna néhány színpadi szövegkönyvéről: (A Lakatos László-, a Felkai Ferenc- és a Harag György-féle változat)
Potential to enhance the prescribing of generic drugs in patients with mental health problems in Austria; implications for the future
No full textScrutiny over pharmaceutical expenditure is increasing leading to multiple reforms. This includes Austria with measures to lower generic prices and enhance their utilization. However the situation for newer antidepressants and atypical antipsychotic medicines (AAPs) is different to PPIs, statins, and renin-angiotensin inhibitor drugs with greater tailoring of therapy and no wish to switch products in stable patients. Authorities welcome generics though given the high costs particularly of single-sourced AAPs. Assess (a) changes in utilization of venlafaxine versus other newer antidepressants before and after availability of generics, (b) utilization of generic versus originator venlafaxine, (c) price reductions of venlafaxine over time and their influence on total expenditure, (d) utilization of risperidone versus other AAPs, (e) suggest potential additional reforms that could be introduced if pertinent to further enhance the use of generics. A quasi-experimental study design with a segmented time series and an observational study. Utilization measured in defined daily doses (DDDs) and total expenditure per DDD and over time. No appreciable changes in the utilization of venlafaxine and risperidone after generics. The reduction in expenditure/DDD for venlafaxine decreased overall expenditure on newer antidepressants by 5% by the end of the study versus just before generics despite a 37% increase in utilization. Expenditure will further decrease if reduced prescribing of duloxetine. Depression, schizophrenia, and bipolar diseases are complex diseases. As a result, specific measures are needed to encourage the prescribing of generic risperidone and venlafaxine when multiple choices are appropriate. Authorities cannot rely on a "Hawthorne" effect between classes to enhance the use of generics. Measures may include prescribing restrictions for duloxetine. No specific measures planned for AAPs with more multiple-sourced AAPs becoming availabl
Kosztolányi és az izmusok : Tanulmányok
No full textDOBOS ISTVÁN
Kapcsolatok A jelentésteremtő nyelv költészettana és a kortárs stílusirányzatok Kosztolányi értekező műveiben
11
VERES ANDRÁS
Izmusok nélkül Kosztolányi és az „izmusok”
58
BENGI LÁSZLÓ
Rítus és intervallum A megújulás tapasztalatai Kosztolányinál
78
BUCSICS KATALIN
Kosztolányi és a freudizmus
97
GYŐREI ZSOLT
Költő és fizikum Kosztolányi és az izmosok
130
HORVÁTH LAJOS
Archaizmusok egy Shakespeare-fordításban
154
SZILÁGYI ZSÓFIA
Élni, mint régen Az anakronizmus, Kosztolányi és az Öregurak
174
TAKÁCS LÁSZLÓ
Kosztolányi és a bovaryzmus
187
VARGA KINGA
Kun Béla elrepült A politikai átalakulások megjelenése
egyes Édes Anna-adaptációkban
200
DOBÁS KATA
Kosztolányi és a bicsérdizmus
224
BUDA ATTILA
„Szeretett tükör előtt állni, nézegetni magát”
Kosztolányi és a ’turizmus’
237
Irodalomjegyzék
26
Can authorities appreciably enhance the prescribing of oral generic risperidone to conserve resources? : findings from across Europe and their implications
No full textGeneric atypical antipsychotic drugs offer health authorities opportunities for considerable savings. However, schizophrenia and bipolar disorders are complex diseases that require tailored treatments. Consequently, generally there have been limited demand-side measures by health authorities to encourage the preferential prescribing of generics. This is unlike the situation with hypertension, hypercholaesterolaemia or acid-related stomach disorders.The objectives of this study were to compare the effect of the limited demand-side measures in Western European countries and regions on the subsequent prescribing of risperidone following generics; to utilise the findings to provide future guidance to health authorities; and where possible, to investigate the utilisation of generic versus originator risperidone and the prices for generic risperidone. Principally, this was a segmented regression analysis of retrospective time-series data of the effect of the various initiatives in Belgium, Ireland, Scotland and Sweden following the introduction of generic risperidone. The study included patients prescribed at least one atypical antipsychotic drug up to 20 months before and up to 20 months after generic risperidone. In addition, retrospective observational studies were carried out in Austria and Spain (Catalonia) from 2005 to 2011 as well as one English primary care organisation (Bury Primary Care Trust (PCT)). There was a consistent steady reduction in risperidone as a percentage of total selected atypical antipsychotic utilisation following generics. A similar pattern was seen in Austria and Spain, with stable utilisation in one English PCT. However, there was considerable variation in the utilisation of generic risperidone, ranging from 98% of total risperidone in Scotland to only 14% in Ireland. Similarly, the price of generic risperidone varied considerably. In Scotland, generic risperidone was only 16% of pre-patent loss prices versus 72% in Ireland. Consistent findings of no increased prescribing of risperidone post generics with limited specific demand-side measures suggests no 'spillover' effect from one class to another encouraging the preferential prescribing of generic atypical antipsychotic drugs. This is exacerbated by the complexity of the disease area and differences in the side-effects between treatments. There appeared to be no clinical issues with generic risperidone, and prices inversely reflected measures to enhance their utilisation
About the aspects and roles of phrasemes in Kosztolányi’s Skylark (1924)
No full textIn this essay I examine the ways in which language functions both as a means of preserving the past and as a marker of change by examining the significance of phrasemes in the novel Pacsirta (Skylark) by Hungarian author Dezső Kosztolányi. In part by examining the ways in which the English and German translators of the novel dealt with the complexities posed by the historically and culturally embedded nature of language, I explore the complex and at times contradictory functions of language in the novel. Kosztolányi’s use of phrasemes in Pacsirta, I argue, exemplifies several of his theoretical ideas about language itself and the roles of language in the mediation of the past
„Minden szó egy világ.”: Idegen szavak a Pacsirtában
No full textEven though Kosztolányi was not a linguist, his concept of language – developed in several essays – has been playing a considerable role in the reception of his oeuvre even assigning him a unique mark among his contemporaries. His approach toward language as such was characteristic yet far from being static during his lifetime; the undoubted influence of historical experiences is elucidated by preceding essays (Szegedy-Maszák, M.; Bengi, L.). The recent study emphasizes one of the most characteristic and telling components of Kosztolányi’s concept, namely his ’purism’ or the rejection of using loan words in his writing. as it has been proven, his protest against loan words – declared in essays as well as the systematic avoidance of loan words in literary works – can be observed from the mid-1910s already; this tendency seems to have been restrained during the beginning of the 1920s but it thoroughly culminated by the 1930s. The study focuses on the novel Skylark (first published in 1923), an homage to the austro-Hungarian Monarchy written by an author whose grandfather took an active part in the Hungarian revolution and War of independence between 1848 and 1849. The main goal of the present study is to demonstrate that loan words frequently used in Skylark function not only as spatial but also as temporal signs; thus, instead of highlighting some foreign nature, loan words serve rather as links to a tradition that was swept away by history.Even though Kosztolányi was not a linguist, his concept of language – developed in several essays – has been playing a considerable role in the reception of his oeuvre even assigning him a unique mark among his contemporaries. His approach toward language as such was characteristic yet far from being static during his lifetime; the undoubted influence of historical experiences is elucidated by preceding essays (Szegedy-Maszák, M.; Bengi, L.). The recent study emphasizes one of the most characteristic and telling components of Kosztolányi’s concept, namely his ’purism’ or the rejection of using loan words in his writing. as it has been proven, his protest against loan words – declared in essays as well as the systematic avoidance of loan words in literary works – can be observed from the mid-1910s already; this tendency seems to have been restrained during the beginning of the 1920s but it thoroughly culminated by the 1930s. The study focuses on the novel Skylark (first published in 1923), an homage to the austro-Hungarian Monarchy written by an author whose grandfather took an active part in the Hungarian revolution and War of independence between 1848 and 1849. The main goal of the present study is to demonstrate that loan words frequently used in Skylark function not only as spatial but also as temporal signs; thus, instead of highlighting some foreign nature, loan words serve rather as links to a tradition that was swept away by history
HTA programme response to the challenges of dealing with orphan medicinal products:Process evaluation in selected European countries
No full textBACKGROUND: Challenges commonly encountered in HTA of orphan medicinal products (OMPs) were identified in Advance-HTA. Since then, new initiatives have been developed to specifically address issues related to HTA of OMPs.OBJECTIVE AND METHODS: This study aimed to understand why these new HTA initiatives in England, Scotland and at European-level were established and whether they resolve the challenges of OMPs. The work of Advance-HTA was updated with a literature review and a conceptual framework of clinical, regulatory and economic challenges for OMPs was developed. The new HTA programmes were critiqued against the conceptual framework and outstanding challenges identified.RESULTS: The new programmes in England and Scotland recognise the challenges identified in demonstrating the value of ultra-OMPs (and OMPs) and that they require a different process to standard HTA approaches. Wider considerations of disease and treatment experiences from a multi-stakeholder standpoint are needed, combined with other measures to deal with uncertainty (e.g. managed entry agreements). While approaches to assessing this new view of value of OMPs, extending beyond cost/QALY frameworks, differ, their criteria are similar. These are complemented by a European initiative that fosters multi-stakeholder dialogue and consensus about value determinants throughout the life-cycle of an OMP.CONCLUSION: New HTA programmes specific to OMPs have been developed but questions remain about whether they sufficiently capture value and manage uncertainty in clinical practice.</p
