342 research outputs found
Effect of methylmercury on fetal neurobehavioral development: an overview of the possible mechanisms of toxicity and the neuroprotective effect of phytochemicals
No full textMethylmercury (MeHg) is a global environmental pollutant with neurotoxic effects. Exposure to MeHg via consumption of seafood and fish can severely impact fetal neurobehavioral development even when MeHg levels in maternal blood are as low as about 5 mu g/L, which the mother tolerates well. Persistent motor dysfunctions and cognitive deficits may result from trans-placental exposure. The present review summarizes current knowledge on the mechanisms of MeHg toxicity during the period of nervous system development. Although cerebellar Purkinje cells are MeHg targets, the actions of MeHg on thiol components in the neuronal cytoskeleton as well as on mitochondrial enzymes and induction of disturbances of glutamate signaling can impair extra-cerebellar functions, also at levels well tolerated by adult individuals. Numerous herbal substances possess neuroprotective effects, predominantly represented by natural polyphenolic molecules that might be utilized to develop natural drugs to alleviate neurotoxicity symptoms caused by MeHg or other Hg compounds
Moral Lessons of XX-th Century's Genocides
No full textIn Polishchuk, M.L., Ph.D., professor of decades taught philosophy at MGIMO (University), led Philosophical Club. He is currently a Visiting Professor at several universities in the world the U.S., Israel, Western Europe, continued regular cooperation with (University). This publication is the author of the presentation on russian of his book "The Great inquiry. The philosophy of the balance of history." ( Moscow, the Canon Plus, 2012.
Two images of Polishchuk in the Polish writing in the interwar period: literature – journalism – field study notes
No full textThe article deals with the diverse images of Polishchuk in Polish writing in the
interwar period. The author analyses selected texts of literary prose (A. F. Ossendowski), journalistic (J. Nowakowski) and ethnographical works (J. Obrębski). As
we may see, Ossendowski in his popular novel In Polish jungle (1935) offered the
mythical portrait of Polishchuk. The legend of so-called “forest people” was also
very popular in Polish fictional literature (J. Weyssenhoff, M. Rodziewiczówna).
Readers favored the artistic image of an inhabitant of Polesia. There were some
polemics arguments about the literary image of Polishchuk in the Polish newspapers (for example J. Nowakowski’s article The letter from Polesia published in
the periodical “Marchołt” in 1936). The more actual observations of Polesia and
its culture were presented by B. Malinowski’s pupil – J. Obrębski in his ethnographical study (1934–1936). His field exploration provided more legitimate facts and
image of living conditions and customs of Polishchuks and therefore did not affirm
provide the myth of [email protected] w Białymstok
Historical Views and the Worldview of M. Rylsky
No full textУ статті А. Поліщук здійснено спробу через реконструкцію фактів біографії українського поета та етнографа М.Рильського визначити формування його світогляду та історичних поглядів. Авторкою проаналізовано особливості середовища у якому зростав М. Рильський, акцентовано увагу на ролі кращих представників української національно свідомої інтелігенції кінця ХІХ - початку ХХ у становленні М. Рильського.In the article, A. Polishchuk attempted to reconstruct the facts of the biography of the Ukrainian poet and ethnographer M.Rylysky to determine the formation of his outlook and historical views. The author analyzed the peculiarities of the environment in which M. Rylsky grew and emphasized the role of the best representatives of the Ukrainian nationally conscious intelligentsia at the end of the 19th and early 20th centuries in the formation of M. Rylsky
What is Behind the Boundary Uncertainty? Yaroslav Polishchuk, 'Frontyrna identychnist: Odesa XX stilittia', Dukh i Litera, Kyiv 2019, 208 pp.
No full textThe author of the review analyses the book of professor Yaroslav Polishchuk Boundary Identity. Odessa of the XX Century. This geopoetical study opens before its reader the whole world of the history and art of the city which played an important role on the cultural map of Ukraine. Speaking about the identity of Odessa and its inhabitants nowadays, we have to say that there are a lot of representations of it. The struggle between the images of the imperiled province and the contemporary Ukrainian port center influences the cultural identification of the city. The review reveals all the ways in which the researcher tries to represent the original image of this metropolis in artistic works and visions
The dynamic of secondary hemorrhagic progression of contusion in traumatic brain injury
No full textVyval M. B., Polishchuk M. E., Perekopaiko Y. M. The dynamic of secondary hemorrhagic progression of contusion in traumatic brain injury. Journal of Education, Health and Sport. 2017;7(1): 369-376. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.292929
http://ojs.ukw.edu.pl/index.php/johs/article/view/4271
The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 754 (09.12.2016).
754 Journal of Education, Health and Sport eISSN 2391-8306 7
© The Author (s) 2017;
This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland
Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License
(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.
This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.
The authors declare that there is no conflict of interests regarding the publication of this paper.
Received: 02.01.2017. Revised 16.01.2017. Accepted: 24.01.2017.
УДК 616.831-001.3-005.1
The dynamic of secondary hemorrhagic progression of contusion in traumatic brain injury
M. B. Vyval, M. E. Polishchuk, Y. M. Perekopaiko
Department of Neurosurgery, National Medical Academy of Postgraduate Education named after P.L. Shupik, Ministry of Health of Ukraine, Kyiv, Ukraine
Traumatology Department, Ternopil City Municipal Hospital of Emergency medicine , Ternopil, Ukraine
Abstract
Introduction. Secondary posttraumatic changes in the brain often determine the clinical flow during traumatic brain injury (TBI). Prevention and early detection of secondary hemorrhagic progression (SHP) is very important for determination of the treatment strategy in patients with brain contusion.
We studied the dynamic of brain contusion and its impact on the clinical course of brain injury. We found that the secondary hemorrhagic progression of contusion occurs in 43% and can be detected at the place of primary brain damage, and far away from it, and often can be seen in patients with a subdural hematoma. The larger contusion has the greater probability of progression and needs for surgical decompression. Progression is associated with the significant risk of clinical deterioration and mortality.
Conclusions. Treatment tactics depends on severity of volumetric effect on the surrounding brain structures and manifestations of herniation syndrome.
Key words: traumatic brain injury, brain contusion, secondary hemorrhagic progression of contusion
Polyphenols in Metabolic Diseases
No full textPolyphenols (PPs) are a large group of phytochemicals containing phenolic rings with two or more hydroxyl groups. They possess powerful antioxidant properties, multiple therapeutic effects, and possible health benefits in vivo and in vitro, as well as reported clinical studies. Considering their free-radical scavenging and anti-inflammatory properties, these substances can be used to treat different kinds of conditions associated with metabolic disorders. Many symptoms of metabolic syndrome (MtS), including obesity, dyslipidemia, atherosclerosis, elevated blood sugar, accelerating aging, liver intoxication, hypertension, as well as cancer and neurodegenerative disorders, are substantially relieved by dietary PPs. The present study explores the bioprotective properties and associated underlying mechanisms of PPs. A detailed understanding of these natural compounds will open up new opportunities for producing unique natural PP-rich dietary and medicinal plans, ultimately affirming their health benefits
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