1,726,345 research outputs found
Astronomische nachrichten, nos 2777-2780
No full textR. R. Astronomische nachrichten, nos 2777-2780. In: Bulletin astronomique, tome 4, 1887. pp. 161-163
EVANGÉLICOS SANGUESSUGAS, PRESIDENCIÁVEIS E CANDIDATOS GAÚCHOS: A DISPUTA PELO VOTO DOS GRUPOS RELIGIOSOS
Full text linkhttps://seer.ufrgs.br/debatesdoner/article/view/2777/164
Title IX. Of Lease (Art. 2668 - 2777)
Full text linkChap. 1. Of the Nature of the Contract of Lease and of Its Several Kinds (Art. 2669 - 2675) Chap. 2. Of Letting Out Things (Art. 2676 - 2744) Chap. 3. Of the Letting Out of Labor or Industry (Art. 2745 - 2777)https://digitalcommons.law.lsu.edu/la_civilcode_book_iii/1009/thumbnail.jp
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Screening-Identified Oxazole-4-Carboxamide KB-2777 Exhibits In Vitro Anti-Coronavirus Activity
No full textBackground/Objectives: Direct-acting antivirals vary by lineage and face rapid resistance. We identified the oxazole-4-carboxamide lead KB-2777 and aimed to define its in vitro activity across α/β-coronaviruses, time-of-addition (TOA) profile, host-response signatures, and combinability with benchmark DAAs. Methods: We tested KB-2777 (≤25 μM) against HCoV-NL63 (LLC-MK2), HCoV-OC43 (Vero E6; MRC-5 for transcript profiling), and PEDV (Vero E6). We quantified extracellular viral RNA by RT-qPCR at 72 h (n = 3) and confirmed activity by spike-protein immunofluorescence (IFA), cytopathic effect (CPE) protection, and TCID50. We compared TOA regimens (full, pre, co, post), evaluated combinations with nirmatrelvir (NL63) or GS-441524 (OC43) using ZIP scores, and profiled infection-context transcripts (IL6, IFNB1, ISG15, NRF2/antioxidant, UPR). Results: KB-2777 reduced viral RNA with EC50 5.27 μM (NL63), 1.83 μM (OC43), and 1.59 μM (PEDV) without cytotoxicity in the tested range. In NL63 post-treatment, inhibition was minimal at 24 h but clear at 48–72 h (EC50 2.42 μM at 48 h; 5.25 μM at 72 h). TCID50 decreased at 48 h (12.5–25 μM, n = 3, p pre ≈ post > co. Combinations were additive to synergistic (ZIP 5.16 with nirmatrelvir; 8.40 with GS-441524). In OC43-infected MRC-5 cells, KB-2777 attenuated IL6, IFNB1, ISG15, and selected UPR transcripts, with limited changes in uninfected cells (n = 3). Conclusions: KB-2777 shows reproducible cell-based anti-coronavirus activity across α/β lineages, a TOA signature consistent with early post-entry host modulation, and favorable, non-antagonistic combinability with DAAs. These findings support target deconvolution, SAR/ADME optimization, and evaluation in primary airway and in vivo models
El rollo de la Torá de la Biblioteca General Histórica de la Universidad de Salamanca (Ms. 2777)
Full text linkThe Historical Library of the University of Salamanca keeps a Torah scroll (Ms. 2777). It has recently been digitized and a brief preliminary description is provided here.La Biblioteca General Histórica de la Universidad de Salamanca conserva un rollo de la Torá (Ms. 2777). Recientemente ha sido digitalizado y se ofrece aquí una breve descripción preliminar
Powers, Caleb, 1869-1932 (SC 2777)
Full text linkFinding aid and scans (Click on Additional Files below) for Manuscripts Small Collection 2777. Letter, 6 December 1902, from Caleb Powers to Lovin Richards, Hillsdale, Kentucky, thanking him and other Republican residents of Simpson County Precinct Number 1 for donations toward his legal expenses in connection with his retrial on a charge of complicity in the assassination of Kentucky governor William J. Goebel. Includes the list of donors and amounts contributed; also includes a letter, 25 July 1903, from J. B. Howard to the postmaster of Hickory Flat, Kentucky, requesting a house-to-house canvass for donations to defend against the same charge
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