1,736,702 research outputs found
Compound 1294 interferes in host cell invasion.
No full text<p>(A) Measurement of β-galactosidase activities in HFF during the invasion process. HFF monolayers were infected by incubating them with 2×10<sup>4 </sup><i>N. caninum (b-Gal)</i> tachyzoites for 2 hours. Prior to this 2 hour invasion phase (timepoint 0′), tachyzoites were suspended either in DMSO (DMSO 0′), in 5 μM compound 1266 (1266 0′) or in 5 μM 1294 (1294 0′). In additional assays, compound 1294 was added at 60 min after initiation of invasion (1294 60′), 90 min (1294 90′) or 115 min (1294 115′) prior to removal of the drug by washing. Cultures were then incubated for an additional 60 min before β-galactosidase activity was measured. There was a significant decrease in β-galactosidase activity (t-test; p<0.001) when compound 1294 was added at the beginning of infection (1294 0′), but not when the compound was added at later timepoints, and no changes occurred when 1294 was added after the infection phase (1294 60′ post-infection. (B–D) Scanning electron micrographs of HFF infected with <i>N. caninum</i> for 3 days. Cultures were maintained in the absence of 1294 (B), in the presence of 2.5 μM 1294 added 2 h post-invasion (C), and in the presence of 2.5 μM 1294 added already at the time point of invasion (D). Cultures were processed for SEM analysis after 3 days. Note the presence of parasitophorous vacuoles in B and C (arrows), and respective absence in D.</p
Safiyyuddin el-Urmevi (1294)
No full textKitap adı:İslam Medeniyetinde Bilimin Öncüleri: Musiki -- Mana Yayınları, İlim Kurdu Yayıncılık ; 186. İslam Medeniyetinde Bilimin Öncüleri Serisi ; 6. Yayın tarihi: 2021. ISBN: 9786052339565. Proje editörü: Mehmet Azimli. Kitap editörü: Sema Dinç. Kitap Bölümü adı: SAFİYYÜDDİN EL-URMEVT (1294)SAFİYYÜDDİN EL-URMEVT (1294), hayatı, çalışmaları ve düşünceleri, medeniyete katkıları
Author E. Hughes, Jr.
No full textBlack and white photograph of Author Art Hughes, Instructor in Business Education, 1955-1957.https://thekeep.eiu.edu/archives_faculty_eh/1294/thumbnail.jp
Brussel, residentie der hertogen van Brabant onder Jan I (1267-1294) en Jan II (1294-1312)
No full textDe Ridder Paul. Brussel, residentie der hertogen van Brabant onder Jan I (1267-1294) en Jan II (1294-1312). In: Revue belge de philologie et d'histoire, tome 57, fasc. 2, 1979. Histoire (depuis l'Antiquité) - Geschiedenis (sedert de Oudheid) pp. 329-341
Augustianie-eremici w Grodkowie (ok. 1294 – ok. 1524)
Get PDFThe aim of the article is to present the history of the Augustinian-Hermit Convent in Grodków. It was the first monastery of the Augustinian Order in Silesia. The research problem is to establish the Convent’s founding and functioning dates. The author believes that the Convent was founded by Henry V the Fat (Brzuchaty). He dates the foundation to the years 1290–1294. He also presents the economic and social history of the convent as well as its social composition. The convent was dissolved at the time of The Reformation.Artykuł prezentuje dzieje klasztoru augustianów-eremitów w Grodkowie. Był to pierwszy klasztor zakonu augustiańskiego na Śląsku. Jednym z problemów badawczych jest ustalenie daty fundacji klasztoru. Autor przypuszcza, że fundatorem mógł być książę Henryk V Brzuchaty, jak również datuje ten fakt na lata 1290–1294. Prezentuje również ekonomiczne i społeczne dzieje konwentu, również związki ze społeczeństwem. Klasztor został rozwiązany w okresie Reformacji
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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