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PENENTUAN DOSIS STERILISASI MEMBRAN SELULOSA MIKROBA DENGAN IRADIASI BERKAS ELEKTRON BERDASARKAN ISO 11137
Get PDFTelah dilakukan perhitungan dosis sterilisasi membran selulosa bakteri dengan iradiasi berkas elektron berdasarkan pada International Standard Organization (ISO) 11137. Pelikel selulosa mikroba dibuat dari fermentasi statis bakteri A. xylinum dalam media yang mengandung air kelapa sebagai sumber mikronutrien. Pelikel kemudian ditekan pada suhu kamar menggunakan alat hand press sehingga dihasilkan membran dengan ketebalan 0,03 ± 0,01 mm. Dosis sterilisasi iradiasi berkas elektron ditentukan berdasarkan ISO 11137 melalui 3 tahap yaitu: penghitungan jumlah kontaminasi awal mikroba (bioburden), penentuan dosis verifikasi dan penetapan dosis sterilisasi menggunakan Tabel 2. Hasil yang diperoleh menunjukkan bahwa nilai bioburden rata-rata batch 1, 2 dan 3 masing-masing adalah 67,4; 92,6; 91 cfu.Sedangkan bioburden rata-rata keseluruhan batch membran adalah 83,7 cfu. Bioburden rata-rata masing-masing batch lebih kecil dari dua kali bioburden rata-rata keseluruhan batch, sehingga bioburden yang digunakan untuk penetapan dosis verifikasi adalah bioburden rata-rata keseluruhan batch. Berdasarkan pada ISO 11137, maka dosis verifikasi adalah 7,8 kGy. Hasil pengujian pertumbuhan mikroba pada 100 sampel membran setelah menerima dosis verifikasi menunjukkan bahwa hanya satu mikroba yang tumbuh sehingga dosis verifikasi dapat diterima. Dari hasil inidisimpulkan bahwa dosis sterilisasi iradiasi berkas elektron untuk membran mikroba pada tingkat Sterility Assurance Level (SAL) 10-6 adalah 21 kGy
PENENTUAN DOSIS STERILISASI MEMBRAN SELULOSA MIKROBA DENGAN IRADIASI BERKAS ELEKTRON BERDASARKAN ISO 11137
No full text
Telah dilakukan perhitungan dosis sterilisasi membran selulosa bakteri dengan iradiasi berkas elektron berdasarkan pada International Standard Organization (ISO) 11137. Pelikel selulosa mikroba dibuat dari fermentasi statis bakteri A. xylinum dalam media yang mengandung air kelapa sebagai sumber mikronutrien. Pelikel kemudian ditekan pada suhu kamar menggunakan alat hand press sehingga dihasilkan membran dengan ketebalan 0,03 ± 0,01 mm. Dosis sterilisasi iradiasi berkas elektron ditentukan berdasarkan ISO 11137 melalui 3 tahap yaitu: penghitungan jumlah kontaminasi awal mikroba (bioburden), penentuan dosis verifikasi dan penetapan dosis sterilisasi menggunakan Tabel 2. Hasil yang diperoleh menunjukkan bahwa nilai bioburden rata-rata batch 1, 2 dan 3 masing-masing adalah 67,4; 92,6; 91 cfu. Sedangkan bioburden rata-rata keseluruhan batch membran adalah 83,7 cfu. Bioburden rata-rata masing-masing batch lebih kecil dari dua kali bioburden rata-rata keseluruhan batch, sehingga bioburden yang digunakan untuk penetapan dosis verifikasi adalah bioburden rata-rata keseluruhan batch. Berdasarkan pada ISO 11137, maka dosis verifikasi adalah 7,8 kGy. Hasil pengujian pertumbuhan mikroba pada 100 sampel membran setelah menerima dosis verifikasi menunjukkan bahwa hanya satu mikroba yang tumbuh sehingga dosis verifikasi dapat diterima. Dari hasil ini disimpulkan bahwa dosis sterilisasi iradiasi berkas elektron untuk membran mikroba pada tingkat Sterility Assurance Level (SAL) 10-6 adalah 21 kGy.
 
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Determination Of Gamma Radiation Sterilization Dose on Bioceramic BCP-Sr-Ag as Bone Graft According to ISO 11137 Standards
No full textOne type of bone graft being developed is alloplastic. The alloplastic that is used is Biphasic Calcium Phosphate (BCP). Bioactivity of BCP can be modified by adding ionic material as doping. Doping BCP with Strontium (Sr2+) and Silver (Ag+) becomes bioceramic which has better characteristics and degradability. BCP-Sr-Ag as a health product needs to be sterilized. One way of sterilization is to use gamma radiation. Sterilization by gamma radiation requires the correct sterilization dose. Based on ISO 11137 the determination of the sterilization dose through 3 steps: determination bioburden, determination of verification dose, and determination of sterilization dose. The aim of this study is to determinate of gamma radiation sterilization dose on BCP-Sr-Ag bioceramic as bone graft based on ISO 11137 through determination bioburden, determination verification dose, and determination of sterilization dose. This research was an in vitro laboratory. A total 30 samples of BCP-Sr-Ag were determined for bioburden using TSA media. A total 100 samples of BCP-Sr-Ag were irradiated with a verification dose using cobalt-60 gamma source. The 100 samples then tested for sterilization using TSA media to determine the sterilization dose. The results of the research showed that the average bioburden values of batches 1,2, and 3 were 56,8;61,8; and 60,5 CFU. The average value of the whole batch is 59,7 CFU. Based on ISO 11137, the verification dose is 7,4 kGy and the sterilization dose is 20,5 kGy. The verification dose of bioceramic BCP-Sr-Ag as bone graft is acceptable so that the gamma radiation sterilization dose can be determined according to ISO 11137. © (2023), (University of Dicle). All Rights Reserved.Indonesian Ministry of Research and Technology; Universitas Airlangga, UNAI
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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