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Ekspresi BMP2 dan TRAF6 pada Jaringan Periodontal setelah Pemberian Ekstrak Kopi Robusta selama Pergerakan Gigi Ortodonti
Get PDFOrthodontic tooth movement occurs due to mechanical stimulation followed by alveolar bone and periodontal ligament remodeling. Bone remodeling is the process of bone resorption in areas of tension and bone formation in areas of tension. Various techniques and drugs are used to speed up orthodontic treatment. This study aims to analyze the expression of BMP2 and TRAP6 on orthodontic tooth movement after the administration of Robusta coffee extract. Twenty-four Wistar rats were divided into 4 groups: C1 (2 weeks) and C2 (3 weeks) groups: rats were given orthodontic mechanical force (OMF) and T1 (2 weeks) and T2 (3 weeks) groups rats were given OMF and Robusta coffee extract. OMF in rats was performed by moving the maxillary right permanent molars mesially with a Niti closed coil spring. Observations were made on the 15th and 22nd day by immunohistochemical examination to determine the expression of BMP2 and TRAP6. Administration of Robusta coffee extract for 2 weeks and 3 weeks increased BMP2 and TRAP6 expression (p <0.05). Administration of Robusta coffee extract increased the expression of BMP2 and TRAP6 in the alveolar bone during orthodontic tooth movement
Hubungan Pengetahuan Orang Tua tentang Pencegahan ISPA dengan Kondisi Sanitasi Rumah di Wilayah Kerja Puskesmas Ambulu
Get PDFAcute Respiratory Infection (ARI) is a disease that often affects children younger than 5 years caused by viruses or bacteria. ARI can be caused by many factors, such as intrinsic and extrinsic factors. Extrinsic factors include the sanitation conditions of the house, such as occupancy density, ventilation, type of floor, humidity, lighting, and maternal factors, such as level of education, age and knowledge. This study aims to identify whether there is a relationship between parents' knowledge about ISPA prevention and the sanitation conditions of homes in the working area of ​​the Ambulu Health Center. This type of research were descriptive correlational with a cross-sectional approach with a sample of 92 respondents, with a sampling technique using simple random sampling. The results of the chi-square statistical test show the valueÏ value = 0.000 (α < 0.05).Data collection was carried out using questionnaires and observation. The results showed that 19 mothers (20.7%) had moderate knowledge and 72 mothers (78.3%) had good knowledge. The sanitary condition of the respondent's house was in the moderate category of 24 (26.1) and the sanitary condition of the house was good as much as 68 (73.9%). It is hoped that health services can provide additional knowledge regarding the prevention of ARI for parents, especially those with children under five. So this can help health services to reduce the number of ARI cases, especially in rural areas that are not exposed to information
Hubungan Family Centered Care terhadap Tingkat Kecemasan pada Anak Prasekolah yang Mengalami Hospitalisasi di Ruang Cempaka RSU Negara
Get PDFHospitalization is a condition where the child must stay in the hospital both planned and emergency to undergo therapy and treatment until the return home. During the process, children and parents can experience events which according to some studies are indicated by experiences that are very traumatic and full of anxiety. Efforts that can be made for health workers, especially nurses to reduce the level of anxiety in children is through Family Centered Care. This study uses cross sectional design. The population in the study were preschoolers who experienced hospitalization in the Cempaka’s Room of the Negara General Hospital is 34 respondents. The research sample used purposive sampling technique. The analysis of this study used the Sprearman Rank test. This study found that Family Centered Care in the Cempaka Room of State Hospital was mostly of good value and the results of anxiety of most children experienced moderate anxiety. The results of the research analysis state p = 0.094 (p value >0.05). There is no correlation between Family Centered Care and the level of anxiety of preschoolers who have experienced hospitalization in the Cempaka Room of the State Hospital
Pengembangan Sensor Antioksidan berbasis Kertas Zonamikro dengan Imobilisasi DPPH pada Sampel Ekstrak Tanaman
Get PDFDevelopment of a paper-based antioxidant sensor using DPPH reagent. This sensor is made using a screen-printing method to create a 5 mm diameter detection zone which is immobilized with DPPH reagents. The analysis was carried out in one step by immobilizing antioxidants/samples in the detection zone. After reduction by antioxidants, DPPH radicals become stable DPPH molecules, resulting in a change in color from purple to pale yellow. The purple intensity of DPPH was inversely proportional to the antioxidant activity of the sample and was measured using the help of ImageJ software. The optimal conditions for using DPPH reagents at a concentration of 5 mM and the volume in each detection zone were 3 µL. Characterization of this sensor analysis was carried out on gallic acid with the response time in the 12-minute, linearity with r = 0,9895, detection limit (LOD) value 0,0349 mM GAE, the quantitation limit (LOQ) value was 0,1164 mM GAE, with precision <2% (RSD), and meets the accuracy range of 97-103%. This sensor is then validated against DPPH spectrophotometry UV-Vis by analyzing antioxidant activity from plant extracts. The results showed no significant differences for the gallic acid equivalent for all samples obtained from the two methods at a confidence level of 97-103%, indicating that the method developed could be relied upon to analyze antioxidant activity from real samples. Finally, the paper-based antioxidant sensor is known to be stable for three days when stored in the refrigerator (2- 4 °C), stable for 2 hours at room temperature (25ºC), and makes paper sensors easy to use for end users
Hubungan antara Efikasi Diri dengan Burnout pada Petani Karet Di PTPN XII Kebun Renteng Jember
Get PDFRubber farmers are one of the professional which is risk of experiencing burnout. The routine of work by rubber farmers which is repeatedly over a long period of time, namely planting, maintenance and tapping can lead to burnout. One of the factors that influence an individual to resist burnout is self-efficacy. This study aims to analyze the relationship between self-efficacy with burnout in rubber farmers at PTPN XII Kebun Renteng Jember Regency. Design of this study were an quantitative correlational with cross-sectional approach. The population was 523 respondents. A total of 227 respondents were obtained by simple random sampling. Randomization of responden by research randomizer. The data collection used the General Self Efficacy (GSE) questionnaire and the Maslach Burnout Inventory-General Survey (MBI-GS). The data analysis used the Spearman test with a significance level of 0.05. The results showed that the median value of self-efficacy was 35, while the mean value of burnout was 40,09. There was a relationship between self-efficacy with burnout in rubber farmers at PTPN XII Kebun Renteng Jember Regency (p-value = 0,001; r = -0,216). The determinant coefficient (r) of 0.216 indicated that the level of correlation is low
Stigma terhadap Gangguan Jiwa dan Kaitannya dengan Praktik Seksisme dalam Budaya Paternalistik Bali
Get PDFStigma toward mental illness is a complex construct incorporating personal, social, and structural. One of the social components that might significantly comprise stigma is the cultural aspect. Asian culture, generally, and Balinese culture, especially, is heavily embedded with the practice of paternalism which is a part of sexism. The practice of sexism as one form of discrimination might imply a high tendency to stigmatize people with mental illness. Therefore, it would be relevant to discuss the possible correlation between stigma and mental illness within the context of the predominant sexism-loaded paternalistic culture in Bali. This literature review covers several subtopics, including stigma and discrimination, sexism and its correlation with mental illness, and cultural aspects that might influence stigma concluded with recommendations for culturally sensitive mental health practice
Efektifitas Terapi Relaksasi Nafas Dalam dan Dzikir terhadap Kadar Gula Darah pada Klien DiabetesTipe II di RS Mitra Medika Bondowoso
Get PDFAlong with the increase in type II diabetes mellitus cases, various efforts made to control blood sugar levels of patients with type II diabetes mellitus include nonpharmacological interventions in deep breathing relaxation and dzikir therapy need to be considered. In addition to being easy and practical, it can be used for daily therapy used by people with diabetes mellitus. The purpose of the study was to determine the effectiveness of deep breath relaxation therapy and dhikir for blood sugar levels in clients of Type II Diabetes Mellitus in the Hospital of Mitra Medika Bondowoso. The research design used a two-group type pretest-posttest design with a total sample of 70 people divided into 2 groups of 35 groups each and given a different intervention that is deep breathing relaxation and dhikr using the Saturated Sampling technique. Then analyzed by Paired t-test and One Way Anova statistical test with significance level α ≤ 0.05 to find out the comparison between two different groups. The results showed that p value = 0.209 (p> 0.05) which means there was nosignificant difference between deep breathing relaxation therapy and dhikr therapy, meaning that it was equally effective in reducing blood sugar levels in clients of Diabetes Mellitus. The conclusion is that deep breath relaxation therapy and dzikir are effective against blood sugar levels in clients of Type II Diabetes Mellitus in the Hospital of Mitra Medika Bondowoso
Hubungan efikasi diri dengan mekanisme koping siswa dalam menghadapi tugas di SMA Negeri 1 Jember
Get PDFAdolescence period is a transition period of human development between childhood and adulthood starting at the age of 12 or 13 years and ending at the last teenage years. Teenagers are in a high school period. In this period, teenagers undergo stress since they faced various jobs or tasks simultaneously, such as school assignments, and the burden of learning which was felt quite hard. Moreover, High School is currently following the 2013 curriculum by applying the Semester Credit Unit where students are required to find out in advance to do the assignments. Teenagers needed the confidence to resolve the demands of school duties. This study identified the relationship between self-efficacy and student coping mechanisms in dealing with assignments. The research design applied correlation analysis with a cross-sectional approach. The data collection technique used was stratified random sampling with 243 respondents. Data collection was carried out using the self-efficacy questionnaire and Children's Coping Questionary. The results of data analysis performed the Pearson correlation that revealed a score of p-value 0.00; r: 0.332; meaning that there was a relationship between self-efficacy and coping mechanisms of students in facing assignments in SMA 1 Jember. Therefore, it was needed teachers and parents support in providing motivation to students so that their self-efficacy of students was able to increase and produce an adaptive coping mechanism.
 
Optimasi Jumlah Etil Selulosa dan Kecepatan Pengadukan dalam Preparasi Hollow Microspheres Kaptopril
Get PDFCaptopril is an Angiotensin-Converting Enzyme inhibitor (ACE Inhibitor) used for the treatment of hypertension. It has been reported that the duration of antihypertensive action after a single oral dose of captopril is only 6–8 h, specific absorption in the stomach, stable at acidic pH and degraded at high pH. These indicate a promising potential of the captopril hollow microspheres system as an alternative to the conventional dosage form. The preparation method used in this study is non-aqueous solvent evaporation. This study aims to determine the amount of ethyl cellulose (EC) and stirring speed to produce hollow microspheres having entrapment efficiency (EE), buoyancy and particle size maximum. Determination of the optimum hollow formula microspheres captopril uses a design factorial of two factors at two levels. The factors used in this study were the amount of EC and stirring speed, while the observed response was EE, buoyancy and particle size. The chosen optimum formula will be verified and characterized (yield, SEM, FT-IR). Formula AB was the optimum formula with EE 90.68%, buoyancy 81.52% and particle size 267.10µm. The verification obtained results in accordance with the prediction of the Design-Expert software. The characterization results obtained a yield value of 98.33%, with a spherical shape, uneven surface morphology, and hollow core. The results of FT-IR analysis showed that there was no interaction between the drug and polymer used in the formulation
Peran Perawat dalam Meminimalkan Kecemasan Orang Tua akibat Hospitalisasi Anak di RSU Negara: Indonesia
Get PDFPain and hospitalization are the main problems seen in children, if a child is being treated in a hospital, children and parents will be easily anxious. The hospitalization period passed by the child will cause anxiety for himself and his parents. Nurses have an important role in involvement and providing nursing care to patients or families of patients who can affect their health so that they have a higher level of health. Nurses have a role as nurses, patient defenders, educators, coordinators, collaborators, consultants, and reformers. This study includes correlational analytic with the research design used is cross-sectional and sampling uses purposive sampling. Parents whose children experienced hospitalization at the Cempaka State Hospital General Hospital in 2019 were mostly ≥25 years old (92.5%) and were dominated by SMP-SMA as many as 26 (38.8%). A total of 43 respondents (64.2%) said nurses at Cempaka room Negara General Hospital had performed their roles well and 24 respondents (35.8%) said the role of nurses was sufficient. The anxiety of parents whose children are being treated at the Cempaka Room General Hospital in 2019 has a lighter anxiety 43 (64.2%) while respondents with moderate anxiety are 20 (29.9%) and respondents with severe anxiety are as many as 4 (6, 0%). The results of the study stated the value of p = 0,000 (p <0.05) which means there is a relationship between the role of care in minimizing hospitalization for children. There is a significant relationship between the role of nurses by minimizing the anxiety of parents due to the hospitalization of children in the Cempaka room Negara General Hospital 2019