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    Pengaruh Ekstrak Daun Pepaya Terhadap Jumlah Sel Limfosit Pada Gingiva Tikus Wistar Jantan Yang Mengalami Periodontitis (The effect of papaya leaves extract to the number of lymphocytes cells to the male-wistar rat's gingiva that undergo periodontitis)

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    Background. Porphyromonas gingivalis (P. gingivalis) is plaque bacteria caused periodontitis with proteolitic characterised that makes some damages to the periodontal tissues. Lymphocytes are chronic inflamed cells which have specific characteristic when periodontitis was occured. Papaya is known as herbal plants, which contains substances which have antimicroba and antiinflamation activities in its leaves. The purpose of this research is to determinate the effect of papaya leaves extract to the number of limfocyte cells to the male-wistar rats gingival that was periodontitis. Twenty male-wistar rats that were divided to the five groups with different treatments. The first group is control of other group, the second group is treatment group that was induced with P. gingivalis and assembled with a ligature, while the remaining of groups were added with the extract of papaya leaves sondation by certain concentration 25% for the third group, 50% for the fourth group, and 75% for the last group after getting some treatments as the second group. The result of the research showed that the highest lymphocytes cells was found to group that was induced by P. gingivalis and assembled with a ligature. In the contrary, the lowest lymphocytes cells was found to the fifth group that was treated with the extract of papaya leaves 75%. It concluded that papaya leaves extract decreased the number of lymphocytes in periodontitis male-wistar rats gingival. The most effectively of papaya leaves extract that was used is 75%. Advanced research about the compound of the extract of papaya leaves which most influential and the mechanism to the decrease of the number of lymphocytes cells are needed. Keywords: Papaya Leaves Extract, Periodontitis, P. gingivali

    Pengaruh Diabetes Self Management Education (DSME) terhadap Resiko Terjadinya Ulkus Diabetik pada Pasien Rawat Jalan dengan Diabetes Mellitus (DM) Tipe 2 di RSD dr. Soebandi Jember (The Influence of Diabetes Self Management Education (DSME) to The Risk

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    Type 2 Diabetes Mellitus (DM) is a glucose metabolism disorders caused by insulin resistance and impaired of insulin secretion and it can cause any chronic complications, such as diabetic ulcers. Diabetes Self Management Education (DSME) can facilitate patients’s knowledge, skills, and abilities for self-care to prevent diabetic ulcers. This research was intended to analyze the influence of DSME to the risk of diabetic ulcers on Type 2 DM outpatients. The research method was quasi experimental with pre-test and post-test with control group design and used consequtive sampling with 40 Type 2 DM respondents divided into 2 groups. Data were analyzed by using Paired T-test and Independent T-test with 95% of CI. The research results showed that P value of Paired T-test in experimental group is 0,000 and 0,015 in control group, while P value of Independent T-test was 0,001 (p < α ; α = 0,05). The conclusion of this research is there was an influence of DSME to reduce the risk of diabetic ulcers on Type 2 DM outpatients in dr. Soebandi Hospital Jember. It is suggested that nurses can provide DSME to prevent diabetic ulcers on Type 2 DM patients and using DSME as a health promotion program.   Keywords: diabetes mellitus, diabetic ulcers, DSME, self car

    Hubungan Pengasuhan Orang Tua dengan Risiko Tindak Kekerasan pada Remaja di Kelurahan Patrang Kecamatan Patrang Kabupaten Jember (The Correlation of Parenting with Risk of Juvenile Violent in Patrang Village District Patrang Jember)

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    Violence was an incident of physical injury, mental and sexual abuse were commonly made bypeople who have a responsibility for the wellnes of the children who was indicated by loss andthreats to the health and wellnes of the child . The purpose of this study was to determined thecorrelation of parenting with violence risk of adolescents in the Village District of PatrangPatrang Jember . The design of this study was used observational analytic design with crosssectional approach . This research was used 92 respondents as a sample by using purposivesampling . The results of the study was showed 50 parents did a good parenting and 62 juvenile(67,4%) didn’t have a violent risk. The Analyzed used chi - square 95 % CI ( α = 0.05), withodds ratios got p value 0.025 < α ( 0.05), and odds ratio ( OR ) 2.929 as the result . Theconclusion of the study was that there a correalation between parenting with the risk of violencein adolescents and the good parenting shall be have 2,929 times chance for decrease the riskof violence in juvenile than the didn’t one.Keywords: parenting , violence , juvenil

    Analisis In Vivo Aktivitas Antihipertensi dari Protein Biji Melinjo (Gnetum gnemon) Terhidrolisis

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    Hypertension is a serious health problem and requires a good handling. An alternative treatment for hypertension is required due to the treatment of hypertension took a long period of time causing unwanted side effects. Melinjo seed hydrolyzed-proteins have an ACE-inhibitor activity, an antihypertensive effect. This study aimed to determine the antihypertensive effects of melinjo seed hydrolyzed-proteins in hypertensive rats. Wistar rats induced with prednisone 1,5 mg/kg body weight and 2% NaCl for 7 days and then treated. There were 7 groups: a normal group K, a group K(-) which is a hypertensive rats without treatment, a group K(+) which is hypertensive rats with captopril 2,5 mg/kg body weight on day 8th, and four treatment groups P1, P2, P3, and P4 which are hypertensive rats with melinjo seed hydrolyzed-proteins with a dose of 5, 10, 20, and 30 mg/kg body weight on day 8th, respectively. Blood pressure was measured before and after treatment every 1 hour for 5 hours. The results showed that melinjo seed (Gnetum gnemon) hydrolyzed-proteins can decrease blood pressure in hypertensive rats.   Keywords: Antihypertensive, Gnetum gnemon, Hydrolized-Protein, Blood Pressur

    Evaluasi Standar Pelayanan Minimal Instalasi Farmasi RSUD Waluyo Jati Kraksaan Sebelum dan Sesudah Badan Penyelenggara Jaminan Sosial (BPJS) Kesehatan

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    Health care is a right of every person to be realized with the efforts to increase community health status. Social Security Agency of Health (Health BPJS) is an organization statutory to set up the health insurance program that worked on January 1, 2014. Hospital as one of the individual health care which part of the health resources that are indispensable in support of health efforts. One of the health care provided by the hospital pharmaceutical care. The first stage is carried out using a questionnaire and the data collection sheet instruments observation of indicators pharmaceutical care. Stages of data processing carried out by methods that include normality test, T test to 2 free samples, Mann Whitney test. The last stage is draw conclusions achievement Waluyo Jati Hospital Pharmacy SPM on Hospital Pharmacy SPM which has been determined by the Minister of Health. The results of the study in Pharmacy Waluyo Jati Kraksaan Hospital shows that Pharmacy SPM achievement of Waluyo Jati Kraksaan Hospital is in conformity set by the Minister of Health of the Republic of Indonesia

    Identifikasi Sanitasi Pasar di Kabupaten Jember (Studi di Pasar Tanjung Jember) (Identification of Market Sanitation In Jember (Studies in Tanjung Market Jember))

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    Market is a public place where a lot of people gathered and hold interaction or relationship withone another. Traditional market has a very important role in the fulfilling the needs, especiallyfor the middle to lower class. Traditional markets in Jember generally appear dirty, and lessservice. The market can be a major pathway for the spread of diseases like cholera cases inLatin America, SARS and Avian Influenza in Asia. To prevent the spread of disease that canoccur in the market, it is required the implementation of environmental sanitation in accordanceto Kepmenkes No: 519/Menkes/SK/VI/2008. This study aims to identify the market sanitation inJember based on Kepmenkes RI No: 519/Menkes/SK/VI/2008. The type of study used is adescriptive analysis method. This study was conducted in August till September 2013 inTanjung Market Jember. This study was identified about location, building, sanitation, clean andhealthy lifestyle, safety, and other facility in Tanjung market Jember. The results showed thatthe Tanjung market is included in the less healthy market criteria. Based on these results, themanager of Tanjung Market is expected to further improve the sanitation of Tanjung Markets tofit the applicable regulation.Keywords: health, market, sanitatio

    Hubungan Tingkat Kognitif Perawat tentang Caring dengan Aplikasi Praktek Caring di Ruang Rawat Inap RSU dr. H. Koesnadi Bondowoso (The Correlation between Nurses Cognitive Level on Caring with Caring Practice Application in the Inpatient Unit RSU dr. H. K

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    Caring is one form of behavior exhibited by a nurse in performing nursing care services. Purpose of this study was to analyze correlation between nurses cognitive level on caring with caring practice application in the inpatient unit RSU dr. H. Koesnadi Bondowoso. Population in this study were 71 nurses RSU dr. H. Koesnadi Bondowoso with 41 nurses as sample. Nurse characteristics data analysis used univariate analysis, whereas for nurses cognitive levels and nurses caring practices application used the chi-square test with α significance level of 5%. Descriptive data analysis of nurses caring cognitive level showed that 26 nurses (56.5%) had good cognitive and 20 nurses (43.5%) had less cognitive. Applications caring practices showed 23 nurses (50.0%) behaved caring and 23 nurses (50.0%) behaved less caring. Results showed that p value = 0.037 with α significance level of 0.05, and thus Ho was rejected, which means there  was a correlation between nurses cognitive level on caring with caring practice application in the inpatient RSU. dr. H. Koesnadi Bondowoso. Odds ratio 4.4 which means the nurse who had good cognitive level on caring would 4,4 times behaved caring compared with nurses who had sufficient cognitive level of caring.   Keywords: cognitive level nurse, caring, caring practice applicatio

    Efek Pemberian Vitamin E (d-α-tocopherol) terhadap Memori Kerja Spasial Tikus (Rattus novergicus) Remaja yang Diinduksi Etanol

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    During neurogenesis process, nerve cells especially hippocampus susceptible to damage when exposed to ethanol. Vitamin E is an antioxidant and capable to protect nerve cells damage. This study aimed to determine the effect of vitamin E (d-α-tocopherol) on spatial working memory of adolescent rats induced with ethanol. The study used 30 days-old rats (Rattus novergicus), weight between 50-100 grams. Total of 25 rats were divided into 5 groups: 2 control groups and 3 treatment groups. K1/K(-) was normal group without ethanol and vitamin E, and K2/K(+) were induced with ethanol. The treatment groups were given ethanol and vitamin E at a dose of 100mg/kgBW; 200 mg/kgBW; 400 mg/kgBBW respectively for P1, P2 and P3. After treatment for 14 days, the rats were tested for spatial working memory using the Radial Arm Maze (RAM) for 10 consecutive days. Spatial working memory was observed by the total number of right arm option which were entered by rats. The average number of right arm maze option for 10 days, were; K (-): (7 ± 0.52), K (+): (3.98 ± 0.66), P1: (4 , 56 ± 0.41), P2: (6.76 ± 1.01) and P3 (6.38 ± 0.63). In conclusion, there was an effect of vitamin E at a dose of 200 mg/kgBW and 400 mg KgBW on spatial working memory of ethanol-induced adolescent rats.   Keywords: ethanol, vitamin E, spatial memory, Radial Arm Maz

    Pengaruh Penambahan Tepung Kacang Merah Terhadap Daya Terima, Kadar Protein, dan Kadar Serat pada Bakso Jantung Pisang (Addition Effect of Red Beans Flour to the Acceptability, Protein Content, and Dietary Fiber of Banana Blossoms Meatballs)

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    Malnutrition is one of the nutritional problems caused by many factors. One contributing factor is the availability of food. The solution offered is diversification. The purpose of this study was to analyze the effect of adding red bean flour to the acceptability, protein content, and dietary fiber on the banana blossoms meatball. This study was a quasi experimental study. The sample was 25 panelist. Data were analyzed by using the power received Friedman test and Wilcoxon Sign Rank Test, protein content were tested using One Way ANOVA test, and dietary fiber were tested using the Kruskal-Wallis test and Mann Whitney test with a confidence level of 5% (α = 0,05). Based on the results of Friedman test acceptability flavor and color have a p value > α (0,05) so there was no significant difference between the addition of various proportions of red bean flour with the taste and color acceptance in banana blossoms meatballs. Acceptance smell texture has p value < α (0,05) so there was a significant difference between the addition of various proportions of red bean flour with the taste and color acceptance in meatball banana. The result of the protein content and fiber content indicates p value < α (0,05) so there was a significant difference between the addition of various proportions of red bean flour with protein content and fiber content on the banana blossoms meatballs. Keyword: Red Beans Fluor, Banana Meatballs, acceptability, protein, and dietary fibe

    Perbedaan OHI-S DMF-T dan def-t Pada Siswa Sekolah Dasar Berdasarkan Letak Geografis Di Kabupaten Situbondo (Difference Of OHI-S And DMF-T On Elementary School Students Based On Geographical Location In Situbondo)

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    Background the level of dental health and a person's mouth can be seen on high and low scores OHI-S, DMFT and def-t. OHI-S (Oral Hygiene Index Simplified) is an idea of the level of cleanliness of teeth and the mouth of a person. DMF-T index is a measurement of permanent tooth caries and def-t in first gear.  Health Profile Data Situbondo in 2010 shows thepercentage of caries rate 77,37% in the ages of pre  school and primary school students (primary school), it can be influenced by one's situation and environmental conditions such as geographical location. The purpose of this research is to know the difference in OHI-S, DMF-T and def-t on elementary school students based on geographical location in Situbondo that coastal areas, lowlands and the hills. This research is research observational analytic with cross sectional approach methods and techniques of sampling this research is purposive sampling so as to get the number of samples of the 450 students. At each of the elementary schools in three districts will be examination of OHI-S, DMF-T and def-t to specify OHI-S index, DMF-T and-t def. Data analysis using different test Kruskal-Wallis and Mann-Whitney. The results of this research show that the value of OHI-S students in coastal areas that is 49% better than any other area. The average DMF-T students in coastal areas 0,56; lowlands 0,97 and the hills 1,20. Average def-t in coastal areas 1,20; lowlands 1,61 and the hills 1,32. The conclusion is no difference in the value of  OHI-S and DMF-T while the value of the def-t there is no distinction. The advice is need for further research based on the classification of age so that the average difference is seen more clearly visible.   Keywords::def-t, DMF-T, Elementary School, Geographical location, OHI-S. Â

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