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Penentuan Kadar Flavonoid pada Ekstrak Daun Tanaman Menggunakan Metode NIR dan Kemometrik (Determination of Flavonoid in Leave Extracts Using NIR and Chemometric)
Get PDFFlavonoids are a group of natural compounds with variety phenolic structures and are found in plants. The aim of this research was to study whether NIR and chemometric methods could be used to determine the flavonoid content. These methods were compared to UV-Vis spectrofotometry. Flavonoid was extracted from plant leaves by ultrasonic and maceration. NIR spectral data of selected leave extracts were correlated with flavonoid content using chemometric. In this study, the chemometric method that used for quantitative and qualitative analysis were Partial Least Square (PLS) and Linear Discriminant Analysis (LDA), respectively. The PLS R2 calibration was 0.9916499 and RMSEC was 2.1521897. In addition, the R2 of LOOCV and 2-Fold-Cross-Validation were 0.9986664 and 0.9823225, respectively. Furthermore, LDA gave accuracy of 100%. The significance of flavonoid content that have been measured by NIR and UV-Vis spectrofotometry was evaluated with paired samples t-test. In conclusion, flavonoid content that have been measured with both methods gave no significant difference.
Keywords: flavonoid, chemometric, LDA, NIR, PL
Pengelolaan Limbah Padat di Fakultas Kesehatan dan Non Kesehatan Universitas Jember (The Solid Waste Management on Health and Non Health Faculty in University of Jember)
Get PDFRecently, the increase of students in University of Jember also resulting increased of activities.This may cause solid waste also being increase. According to UI’s GreenMetric UniversitySustainability Ranking, University of Jember have tended to decrease in realizing green campuswhich the one of criteria was solid waste management . Based on early study, health and nonhealth faculty was collected in open area in each faculty, being mixed, and burned. This researchaim to describe the solid waste management on health and non health faculty in University ofJember. This research used descriptive observational approach. Unit analysis in this researchwere all health and non health faculty in University of Jember then two health and two non healthfaculty was choosen consist of Public Health Faculty, Faculty of Dentistry, Faculty of Agricultural,and Faculty of Economic. The result of the research showed that Faculty of Economic has thehighest mean weight of solid waste 36,88 kg/day and the mean volume 742,05 liters/day whileFaculty od Dentistry has the lowest mean weight of solid waste 19,38 kg/day and mean volume397,79 liters/day. The conclusion of this research were solid waste management includereduction of solid waste still not comprehensive and handling of solid waste still mixed, heaped inopen place, and burned.Keywords:solid waste, solid waste management, University of Jember
Potensi Penggunaan Obat yang Tidak Tepat pada Peresepan Pasien Geriatri Rawat Jalan di RSD dr. Soebandi Jember Berdasarkan Beers Criteria (Potentially Inappropriate Medication Based on Beers Criteria in Geriatric Outpatients of dr. Soebandi District Hosp
Get PDFInappropriate medication in geriatric is a serious problem because of its high morbidity, mortality, and healthcare costs. Beers Criteria 2012 is the compilation drugs that potentially inappropriate on geriatric patients. The objective of this study was to observe the percentage of inappropriate medication in geriatric outpatients prescription.This study used observational descriptive and retrospective design. The study showed that 69 patients (18.30%) from 377 patients prescribed with 92 inappropriate medication, 20 medication with strong and high quality evidence to be avoided based on Beers Criteria 2012. Amitriptyline was the most prescribed potentially inappropriate agents of 17 events.
Keywords: geriatric, beers criteria,outpatient
Uji In Vitro Efek Ekstrak Etanol Biji Kakao (Theobroma cacao) sebagai Antibakteri terhadap Propionibacterium acnes (In Vitro Test of the Effect of Cocoa Beans (Theobroma cacao) Ethanolic Extract as an Antibacterial against Propionibacterium acnes)
Get PDFAcne vulgaris is a chronic inflammatory disease of the pilosebaceous follicle, characterized by comedones, papules, pustules, cysts and nodules in certain sites of predilection, such as face, neck and back. Propionibacterium acnes are the most recognized bacteria as a key factor for the development of acne. The purpose of this research was to identify the antibacterial effect and Minimum Inhibitory Concentration (MIC) of ethanolic extract of Cocoa beans (T. cacao) against the growth of P. acnes by in vitro method. Antibacterial activity was measured by disk diffusion (Kirby Bauer) method. This was a quasi-experimental with posttest only control group design. Samples used was colony of P. acnes. Concentration of test solution used was 7.81; 15.62; 31.25; 62.50; 125; 250; 500; and 1000 mg/ml. Positive control used clindamycin suspension and negative control used sterile distilled water. By direct measurement, MIC was obtained at the dose of 31.25 mg/ml, by using linier regretion statistical analysis, the quantitatif MIC showed at the dose of 16.93 mg/ml. Analysis using ANOVA showed significance value p=0.000 (p<0.05). In conclusion, ethanolic extract of Cocoa beans had an antibacterial effect on P. acnes by in vitro method. Â Keywords: antibacterial effect, cocoa beans, Propionibacterium acne
Gambaran Proses Kegiatan Pos Pembinaan Terpadu Penyakit Tidak Menular di Puskesmas Sempu Kabupaten Banyuwangi (The Description of Activity Process for the Integrated Development Post of Non-Communicable Disease (IDP of NCD) at Sempu Public Health Centre i
Get PDFSempu Public Health Centre (PHC) where the IDP of NCD activity was only applied
under 1% in 2014 which the fact remains that Sempu PHC ironically is the first PHC
which has IDP of NCD in Banyuwangi regency. This research aimed to find out how
Posbindu PTM Al-Mubarok activity worked in Sempu PHC. This research used
descriptive study with qualitative data supported. The informants of this research were
purposively taken which included coordinator surveillance of Health Department in
Banyuwangi regency, coordinator IDP of NCD, midwife, nurse, two cadres, the work
partners and two IDP of NCD members. This research collected the data by doing
interview, attentive observation and triangulation technique. Then, the data gathered
were analyzed descriptively. The result showed that activity process of Posbindu PTM
Al-Mubarok in Sempu PHC was different with IDP of NCD guidelines. The process did
not go well because of the input which included the insufficient of human resources,
incomprehensive and minimal training, insufficient of equipments, the lack of public
awareness, the financial dependence and the implementation method which was not
regularly conducted every month.
Keywords: process, IDP of NC
Analisis Efektivitas Biaya Penggunaan Antibiotik terhadap Pasien Sepsis Pediatrik di Rawat Inap RSD dr. Soebandi Kabupaten Jember pada Tahun 2014 (Cost effectiveness Analysis of Antibiotics in Hospitelized Pediatric Sepsis Patients at RSD dr. Soebandi Je
Get PDFAntibiotics play an importent role in sepsis therapy. Inappropiate antibiotic theraphy leads to resistance of antibiotic resulting increase length of stay (LOS), mortality, and higher cost. The purpose of this study was to determine the most effective empirical antibiotic based on cost effectiveness analysis (CEA) in pediatric patients with sepsis at RSD dr. Soebandi in 2014. This study observed medical and payment records retrospectively. From 152 patient analyzed, 51 patients included and 136 patients were excluded because of the antibiotic theraphy less than three days, the age more than 18 years old and the data was not complete. The effectiveness parameter of this study were length of stay (LOS), length of stay antibiotic related (LOSAR) and 28-days mortality. According to this study, ampicillin sulbactam plus amikacin combination had shorter LOS (13,82 days) than other antibiotics. However monotheraphy ampicillin sulbactam had shorter LOSAR (7.13 days) and lower 28-days mortality (50.00%). The total cost and antibiotic cost analysis showed that ampicillin sulbactam plus amikacin combination was cheaper than other antibiotics (Rp 5,130,000.00 ± 500.00). Based on CEA and quadrant analysis ampicilin sulbactam combination plus amikacin was the most cost effective with low cost and high effectiveness (quadrant II) than other antibiotic.  Keywords: cost effectiveness, antibiotic, sepsi
Pengaruh Therapeutic Exercise Walking terhadap Sirkulasi Darah Perifer pada Pasien Diabetes Melitus Tipe 2 di Kelurahan Gebang Kecamatan Patrang Kabupaten Jember. (The Effect of Therapeutic Exercise Walking on Pheripheral Blood Circulation in Patients wit
Get PDFPathological change experienced by patients with type 2 diabetes mellitus is impaired peripheralblood circulation, especially in the lower limbs and feet. Peripheral blood circulation can be examinedby measuring Ankle Brachial Index (ABI). Therapeutic exercise walking is one of physical activitieswhich can improve blood circulation. This research goal was to analyze the effect of therapeuticexercise walking on peripheral blood circulation in patients with type 2 diabetes mellitus. Theresearch design was randomized control group pretest-posttest design. The sample size was 15respondents as control group and 15 respondents as treatment group. Data was analyzed by usingdependent t-test and independent t-test with significant level of 0.05. This result showed a significantincrease of ABI after therapeutic exercise walking in the treatment group (p= 0.001). However therewas a significant decrease of ABI between pretest and posttest in control group (p=0.010).Independent t-test indicated a significant difference of ABI between treatment group and controlgroup (p=0.000). So, it can be concluded that there is an influence of therapeutic exercise walking onthe peripheral blood circulation in patients with type 2 diabetes mellitus. Nurses should applytherapeutic exercise walking to improve peripheral blood circulation in patients with type 2 diabetesmellitus.Keywords: type 2 diabetes mellitus, therapeutic exercise walking, ankle brachial inde
Analisis Faktor Individu, Faktor Organisasi dan Kelelahan Kerja Terhadap Stres Kerja Pada Perawat (Studi di Ruang Rawat Inap Kelas III RSU dr. H. Koesnadi Kabupaten Bondowoso) (Analysis of Individual Factors, Organization Factor and Occupational Fatigue W
Get PDFHospital is a health service place. The service claims can create some danger like work
stress. Based on the preliminary studies that has been done at General Hospital dr.H
Koesnadi, Bondowoso district , found that 67 % nurses experienced the occupational
fatigue and work stress. The work stress is influenced by some factors like individual
factors (gender, age, length of service and level of education), organization factor like
work shift and occupational fatigue in the hospital's employee. Human resource has
potential about the work stress of nurse in handly the patient directly. The purpose of this
research is to analyze the relation between individual factors, organization factor and
occupational fatigue in the work stress. The method that used in this research is
analytical observation with the cross sectional design. The sampel of this research is 46
respondents that spread over 5 inpatient room 3rd grade.The result of this research
showed that there was a significant relation between individual factors and work stress
(p = 0,004), the relation between the organization factor and the work stress (p = 0,038).
It is also known that there was a relation between occupational fatigue with the work
stress (p = 0,047)
Keywords: Individual Factors, Organization Factors, Occupatiunal Fatigue, Work Stres
Pengaruh Metode Contextual Teaching and Learning (CTL) dengan Pendekatan Somatis, Auditori, Visual, Intelektual (SAVI) Terhadap Kesiapsiagaan Bencana (medical first respondent) Gunung Meletus pada Karang Taruna di Desa Rowosari Kecamatan Sumber Jambe Kabu
Get PDFPreparedness is a activities undertaken to anticipate disasters through the organization as well as through measures appropriate and useful. Build preparedness is an important element, but it is not easy to do because it involves the mental attitude and culture and discipline in a society. Preparedness is the most strategic stages because it determines the resilience of the community members in facing a calamity. This research aims to improve the knowledge and attitude of disaster preparedness in the youth in the village of Rowosari. This study design is a pre-experimental design with one group pretest posttest. The study sample as many 20 karang taruna and using simple random sampling. The data analysis uses dependent t-test, with an average increase in the value of disaster preparedness 1 hour after the intervention with a value of 45.25 pretest and the posttest-1 value of 89, the value of one week after the intervention values of 45.25 pretest and posttest-2 values 87, 65, a decline in the average value of disaster preparedness at posttest -1, posttest with a value of 89.3 posttest-1 and posttest- 2 87.65 value. This result shows that the value of p 0:00 < 0:05 (a). The conclusion from this research is that there is a very significant influence on disaster preparedness mountain erupted after the intervention given by the CTL method SAVI approach. The recommendation of this study is the method of CTL with SAVI approach recommended in the community to improve the knowledge and attitude of disaster early warning, transportation evacuation and disaster preparedness bandaged splint. Â Keywords: disaster preparedness, contextual learning methods, methods of somatic visual auditory intellectua
Faktor yang Berhubungan dengan Penggunaan Alat Pelindung Diri secara Lengkap pada Bidan (Studi di Wilayah Kerja Kabupaten Bondowoso) (Determinant of Complete Personal Protective Equipment Using for Midwives (study in Work Region of Bondowoso District)
Get PDFMidwives have to wear PPE completely, such as head cover, goggles, mask, gloves, apron, andboots. But not all of them using PPE completely for 75% in Bondowoso. This study aims was toanalyze the factors related to completely using of PPE for midwives in work region of Bondowoso.This study held in Mey 2015-February 2016. This study used cross sectional approachment. Thepopulations of this study were 116 Delima midwives in Bondowoso. The result showed that themidwives’s knowledge was in the medium level, most were positive attitude, they had sameeducation level (between D3-D4), their age were about 35-44 years old, and most of them hadbeen working for 21-30 years. The midwives wore PPE completely in I stage (2,8), II and III stage(11,1) and all of them did not wear PPE completely in IV stage.There was significant correlation ofattitude to complete PPE using for midwives in I stage and no significant correlation of knowledge,attitude, education, age, work stage to complete PPE using for midwives of II and III stage inBondowoso. There was no significant correlation between the PPE availability with complete PPEusing for midwives in I stage and significant correlation between the PPE availability with completePPE using for midwives of II and III stage in Bondowoso. There was no significant correlationbetween training and monitoring with complete PPE using for midwives of I, II, III stage inBondowoso.Keywords: factors individual , PPE availability, training and monitoring factor