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Hubungan Sanitasi Lingkungan dengan Kejadian Infeksi Soil Transmitted Helminths pada Anak Sekolah Dasar di Jember
Poor environmental sanitation is suspected to be one of the causes of soil transmitted helminthes (STH) infection. Environmental sanitation consists of water sources, latrine, sewerage, garbage disposal facilities, and floor type. The objective of this study was to investigate the relationship between environmental sanitation and the incidence of STH infection in primary school children. This was an observational analytic study with cross-sectional design. The subjects were 80 students of two elementary schools in Jember. Stool samples were collected and examined by Kato-Katz method. Data of environmental sanitation was collected by questionnaire and direct observation. Kato-Katz examination showed that 9 samples (11,3%) infected by Ascaris lumbricoides. The majority respondents had not fulfilled requirements of good environmental sanitation. The result of Spearman test showed that there was a significant correlation between STH infection and latrine (p=0,02) but there were no significant relationship between STH infection and environmental sanitation (p = 0.165), gender (p = 0,669), age (p = 0,92), water source (p = 0.084), sewerage (p = 0.146), garbage disposal facilities (p = 0,728), and floor type (p = 0,065)
Perbedaan pH, Viskositas dan Volume Saliva setelah Berkumur dengan Obat Kumur Sintetik yang Mengandung Chlorhexidine dan Larutan Propolis pada Anak Usia 11-12 Tahun
Dental caries is a process that begins with dissolution of enamel causing damage to the dental component by several factors, such as saliva. The occurrence of diseases in the oral cavity is prevented by the use of synthetic mouthwash containing chlorhexidie, but the using of synthetic compounds causes mutagenic effects on the oral cavity, so it needs alternative by using natural ingredients that have antibacterial power and smaller side effects. The purpose of the study was to investigate the difference of pH, viscosity and volume saliva after gargling with synthetic mouthwash containing of chlorhexidine and propolis solution for children age 11-12 years in Pondok Pesantren Nurul Islam Antirogo Jember. This study used pra-experimental One Shoot Case Study with total sampling in Pondok pesantren Nurul Islam Antirogo Jember. As many 25 students were recruited for the study. The result showed that after gargling with propolis solution can be increase of pH saliva, decrease of viscosity saliva and increase of volume saliva for children age 11-12 years in Pondok Pesantren Nurul Islam Antirogo Jember
Peran Keluarga Terhadap Perilaku Mahasiswa yang Mengkonsumsi Minuman Beralkohol di Kabupaten Jember
Adolescents in the age range of 17-21 years are generally students, who are expected to have good cognitive skills and be able to solve problems effectively. Teenagers who are unable to solve problems sometimes do something that is harmful to themselves such as consuming alcoholic beverages. The role of the family such as parenting and family conditions is one of the causes of adolescents consuming alcoholic beverages. This study aims to determine the role of families in the behavior of students who consume alcoholic beverages in Jember Regency. The theory used by researchers is Social Learning from Bandura. This research is a descriptive study with a qualitative approach. Determination of research informants using snowball techniques. Data collection uses in-depth interviews, documentation and passive participatory observation. Based on the results of the study it was found that the all-free parenting style, lack of trust given by parents to involve children in making decisions and ineffective time spent by parents for families so that children behave deviant. Keywords: Family, teenagers, alcoholic drinks, social learnin
Optimasi Asam Glikolat dan Asam Sitrat dalam Krim Tabir Surya Kombinasi Titanium Dioksida, Avobenzone dan Octyl Methoxycinnamate
Ultraviolet (UV) radiation is the main cause of sunburn and skin cancer. The adverse effects of UV radiation are solved by sunscreen as protection for longer outdoors. In this study, optimization of glycolic acid and citric acid in sunscreen cream combination of titanium dioxide, avobenzone, and octyl methoxycinnamate were investigated using simplex lattice design method. The sunscreen cream evaluation includes physicochemical testing (organoleptic, homogeneity, emulsion type, spreadability, viscosity, and pH) and sunscreen effectiveness (SPF, % erythema transmission, and % pigmentation transmission). The value of physicochemical testing are 5,96 cm - 6,3 cm of spreadability testing; 83,33 dPa.s – 108,33 dPa.s of viscosity testing; 4,06 – 4,67 of pH testing. The value of sunscreen effectiveness are 9,79 – 13,35 of SPF testing; 4,55x10-06 - 0,15x10-06% of % erythema transmission; 5,77 – 7,16 % of % pigmentation transmission. The optimum formula was obtained by combining glycolic acid 2% and citric acid 0% with a desirability value of 0,649
Pengaruh Vitamin C terhadap Fragilitas Osmotik Eritrosit pada Mahasiswa Kedokteran Universitas Jember yang Mengalami Stres Psikologis
Medical students are constantly getting stress that could lead to oxidative stress where the level of free radicals is higher than the level of antioxidants in the body. Free radicals can bind to erythrocyte membranes and alter membrane structure that lead to the integrity of the erythrocyte membrane resulting in decreased erythrocyte ability in preventing hemolysis. Vitamin C is an antioxidant that could prevent free radicals bond to erythrocyte membrane. Vitamin C works by donating electrons to free radicals and prevent binding to erythrocyte membranes. The purposed of this study was to determine the effect of vitamin C consumption on osmotic fragility of erythrocytes in medical students with psychological stress. This research was clinical trial research with quasi experimental with pretest-posttest control group design. Researchers used Depression Anxiety Stress Scale (DASS) questionnaire to measure the stress level. Data analysis using T test obtained mean of percentage of hemolysis between pretest and posttest was p= 0,02. It can be concluded that there is significant difference on osmotic fragility due to Vitamin C consumption in medical Student of Jember University with psychological stress
Sistem Infomasi Geografis Pemetaan Penyebaran Penyakit ISPA, Hipertensi, dan Asma Berbasis Web Di Kabupaten Bondowoso
Unfavorable environmental conditions, economic factors and public health behavior are still bad, causing the number of cases of morbidity caused by tropical diseases is still high. Health agency programs in preventing and eradicating disease will be very effective when receiving support from an information system to review the spread of disease. Referring from 2015 East Java Health Profile, the highest AKI in 2015 was in Bondowoso with 188 per 100,000 live births or as many as 19 people. The types of diseases with the highest number of patients were acute upper respiratory tract infections reaching 31,457 patients. The Geographical Information System for Mapping the Spread of ISPA, Asthma and Hypertension in Bondowoso Regency was prepared using the Google Fusion Table (GFT). This system can be accessed quickly, easily, requires an internet network and can provide information on mapping the spread of ISPA, asthma and hypertension in the Bondowoso area. The map on the system is able to display information including sub-district names, number of cases, number of cases ISPA, Asthma, and Hypertension specifically year 2012 and 2013. This system uses polygon features to mark sub-districts with different colors according to the number of cases. The system also provides a menu to change data for admins who have access rights.
Keywords— Asthma, GFT, Hypertension, ISPA, Mapping
Efek Seduhan Kopi Robusta terhadap Jumlah Limfosit pada Daerah Tarikan Ligamen Periodontal Gigi Marmut (Cavia Cobaya) yang Diinduksi Gaya Mekanis Ortodonti
Malocclusion is an occlusion that deviates from the normal state, so it needs to be treated using an orthodontic device. The formation of new alveolar bone after obtaining an orthodontic force will be surrounded by osteoid bones are not stable enough (relapse). Robusta coffee (Coffea robusta) has flavonoids which can increase lymphocyte proliferation. The purpose of this study was to analyze the effect of robusta coffee on the number of lymphocyte cells in the tension area of marmot’s (Cavia cobaya) periodontal ligament which induced by mechanical orthodontic forces. This type of research is laboratory experimental with the Post Test Only Control Group Design. The average number of lymphocyte cells in group A = 0.75, B = 1.45, C = 1.26, D = 1.54. One-way Anova test results showed that the number of lymphocyte cells in all groups showed a significant difference (p <0.05). The results of the post hoc LSD test showed that group A had significant differences with group B and group D (p <0.05). While group C did not have a significant difference with group A (p> 0.05). The conclusion obtained is that the provision of robusta coffee brew for 2 weeks can increase the number of lymphocyte cells in the tension area of marmot’s (Cavia cobaya) periodontal ligament which induced by orthodontic mechanical forces compared to without robusta coffee brew
Optimasi Hydroxypropyl Methylcellulose dan Chitosan pada Tablet Floating-Mucoadhesive Diltiazem Hidroklorida Menggunakan Desain Faktorial
Diltiazem HCl is one of the drugs used for hypertension treatment. It requires frequent dosing, which is why diltiazem HCl needs to be formulated into preparations using a controlled release drug delivery system. The combination of floating and the mucoadhesive system is expected to increase the stomach's retention of the dosage form. This study aimed to determine the optimum composition of hydroxypropyl methylcellulose (HPMC K100M) and chitosan for floating mucoadhesive diltiazem HCl tablet. Tablets that have been prepared were evaluated for the tablet's physical characterization, powder flowability test, dissolution test, floating ability, and mucoadhesive test. Tablets were optimized using a factorial design, and the data were analyzed using design expert 11.0.0. The results showed that the optimum formula for polymer combination in diltiazem HCl tablet was 175 mg for HPMC K100M and 50 mg for chitosan. The combination of polymers with this amount can produce a floating lag time of 45,333 seconds, floating duration time >12 hours, and the strength of mucoadhesive is 81,633 grams
Efektivitas Ekstrak Biji Srikaya (Annona squamosa L.) sebagai Bahan Pembersih Gigi Tiruan terhadap Daya Hambat Pertumbuhan Streptococcus mutans pada Basis Akrilik Heat Cured
The rough surface of a heat cured acrylic resin as a denture base can cause a pathogenic buildup of plaques and biofilms, so an effort to clean the denture base is needed. The available denture cleaning chemicals are proof of some disadvantages, so it is necessary to do research on alternative natural ingredients. Srikaya seed extract using ethanol 96% solvent has been shown to have antibacterial activity and with its various properties, so that it has the potential to become denture cleaning agents. Samples were made based on ADA No.17 specifications with 5 samples in each of the 6 treatment groups, sampling using Simple Random Sampling. Samples contaminated with S. mutans were soaked in srikaya seed extract 25%, 50%, 75%, 100%, 0.5% NaOCl and sterile aquadest. There was a significant difference (p <0.05) in each treatment group. There is an influence of the difference in concentration of srikaya seed extract on the growth of S. mutans bacteria on a heat cured acrylic base.
Keywords: heat cured acrylic resin, S.mutans, srikaya seed extract, absorbanc
Efek Pati Resisten Singkong (Manihot esculenta Crantz) terhadap Indeks HOMA-IR dan HOMA-B Tikus Model Diabetes
Insulin resistance is a condition in which target organs fail to respond normally to insulin. Cassava contains 9,69 percent starch that resist to digestive enzyme in intestine and has been shown to increase insulin sensitivity and enhance β cell function. The aim of this study was to analyze the difference effect of native cassava starch and cassava resistant starch consumption on insulin resistance and β cell function indexes. This study was quasy experimental research with post-test only control group design using 16 male wistar strain rats divided into four groups: K1 (normal rats with standard diet), K2 (diabetic rats with standard diet), P1 (diabetic rats with native cassava starch diet) and P2 (diabetic rats with cassava resistant starch diet). The rats were fed with high fat diet and injected with low-dose streptozotocin to mimic the patogenesis of type 2 diabetes. The rats were then fed with assigned diet for 28 days. The data collection was obtained from laboratory examination of fasting plasma glucose and fasting plasma insulin to determine HOMA-IR and HOMA-B indexes. Post Hoc analysis showed no difference in both indexes between native cassava starch and cassava resistant starch fed groups (p>0,05)