KU Leuven Research Data Repository
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Replication Data for: Policy advisory bodies during crises: a scoping review of the Covid-19 literature in Europe
No full textThis repository contains supplementary material for our paper "Policy advisory bodies during crises: a scoping review of the Covid-19 literature in Europe" (Bouchat et al). The dataset is comprised of 1) the full search queries run in Scopus and Web of Science to identify publications that examined the topic of Covid-19 policy advisory bodies in Europe and 2) the full list of numbered references that examined the topic of Covid-19 policy advisory bodies in Europe. We invite scholars interested in Covid-19 policy advisory bodies to reuse the list of references
Replication Data for: "Enhancing model identification with SINDy via nullcline reconstruction"
No full textArchived version of replication data used for the manuscript "Enhancing model identification with SINDy via nullcline reconstruction". Instructions on the data can be found in the ReadMe file here and the Gitlab respository
A Comparison of the Immediate Effects of Verbal and Virtual Reality Feedback on Gait in Children with Cerebral Palsy
No full textThe dataset contains kinematic and kinetic parameters as well as discrete gait variables of children with cerebral palsy walking on a treadmill in three conditions: Baseline walking condition, a condition in which verbal feedback on hip extension was given during walking and a condition in which vertual reality feedback on hip extension was given during walking
MRR observations taken at Princess Elisabeth Station, Dronning Maud Land, East Antarctica
No full textMRR (Metek Micro Rain Radar 2) recordings taken at the Belgian Princess Elisabeth Station, Dronning Maud Land, Antarctica.
Last updated on 2024-03-22 with data up until 2023-09-12
Replication Data for: Decarbonization of Existing Heating Networks through Optimal Producer Retrofit and Low-Temperature Operation
No full textA dataset containing the structure, input parameters and optimization results of the heating network and heat producers used in the test case of the paper "Decarbonization of existing heating networks through optimal producer retrofit and low-temperature operation".
The optimization results can be replicated using the methodology and formulations described in the paper
Replication Data for: COHERENS-SWAN COUPLED-SET
No full textThis dataset contains the files necessary to replicate all test cases of the COHERENS-SWAN coupled-set.
It includes the compilation bash files, fortran code files and raw files of case specifiec data.
It does not include the original codes of COHERENS and SWAN numerical models. These open source models need to be obtained directly from the corresponding institute.
The current data set does also not include the wind and pressure data fields. Those can be obtained directly through the ECMWF services
Replication Data for: Robust vision-based estimation of time-varying structural parameters using Kalman filtering
No full textData contained in the article: 'Robust vision-based estimation of time-varying structural parameters using Kalman filtering'.
The datasets include:
- position data for a slider-crank system moving in two different dynamic settings, low speed (10 rad/s) and high speed (60 rad/s). These measurements are obtained by vision data captured with a stereo camera setup.
- estimation results obtained by applying Kalman filtering to the experimental data.
- simulated data used in virtual estimation experiments on rigid Multibody systems, and the related Kalman filtered results.
Data is contained in .7z archives which contain the .csv files with the data used in the figures of the paper
Automotive Experimental Reference Data Set: LMSD Concept Car, Lommel (BE), 2023
No full textThis repository contains an experimental reference data set recorded with the LMSD Concept Car research validation vehicle platform. The sensor set employed for this campaign consists of two types of sensors:
Automotive-grade on-board sensors (see Table_On-boardSensors.png)
High fidelity reference sensors:
Two wheel force transducers on the front axle: Kistler RoaDyn S635
Optical velocity sensor: Kistler Correvit S-350
All tests have been performed on asphalt or concrete surfaces in dry conditions running tyre dimensions 235/55R19 front and 235/60R18 rear
Replication Data for: An Efficient Structured Perceptron for NP-Hard Combinatorial Optimization Problems
No full textDevelop an efficient model of the Structured Perceptron (SP) to learn the objective function of a MOCOP. Evaluation of three techniques to apply the SP on NP-hard optimization problems: 1) using heuristic solving methods during the learning process, 2) solving well-chosen satisfaction variants of the problems, 3) caching solutions computed during the learning process and reusing them. Experiments confirm the validity and speed-ups of these techniques, enabling structured output learning on larger combinatorial problems than before
Characterization of in vitro model based on primary culture of human mammary epithelial cells (hMECs): barrier integrity and functionality of transport routes.
No full textThis data set contains results related to the characterization of an appropriate in vitro model for the human blood milk barrier. The aim of the present study was to develop and characterize a human cell-based in vitro model capable of quantifying transfer of xenobiotics across the blood milk barrier. In the present study, both primary mammary epithelial cells (hMECs) and immortalized cell lines (MCF-7, MCF-10A and PMC42-LA) were evaluated for this purpose. The results (transepithelial electrical resistance and sodium fluorescein leakage) showed that hMECs formed a tight barrier after +/- 35 days of culture on transwell inserts in the presence of 10 % Fetal bovine serum (FBS). Indeed, epithelial morphology and presence of tight junctions was confirmed in the model. In the present study, the human cell lines did not form a tight barrier in a reproducible manner under the evaluated culture conditions (Monolayer_integrity_cell_models.ods). In addition, primary cells are the most biorelevant model. Therefore, hMECs were suggested as appropriate model for the human blood milk barrier. Furthermore, the apparent permeability of probe substrates for different transport routes were evaluated in three independent experiments (Permeability_L016.ods, Permeability_L018.ods, Permeability_L021.ods). Probe substrates were fexofenadine hydrochlode for P-glycoprotein, CDFDA for multidrug resistance-associated protein (MRP2/3, ABCC2/3), sulfasalazine for breast cancer resistance protein (BCRP, ABCG2), methotrexate hydrate for organic anion Transporter (OAT, SLC22A6/7/8/9) function, atenolol for paracellular transport, propranolol hydrochloride for passive transcellular transport, and metformin hydrochloride for organic cation transporter (OCT, SLC22A1/2/3). The results show that the model differentiates between the paracellular and transcellular transport route. However, the probe substrates used in the current study suggest limited function of carrier-mediated transport routes (OCT, OAT, P-gp, MRP and BCRP) in the hMECs in vitro model. The integrity of the monolayer was confirmed after the expeirments by measurement of the transepithelial electrical resistance and sodium fluorescien leakage. These results were partly in agreement with mRNA array data also generated for the current in vitro model. Altough future efforts should further clarify the role of membrane transporters, the hMECs in vitro model shows potential to evaluate the permeability of medicines across the blood-milk barrier.
Project Info:
ConcePTION (Building an ecosystem for better monitoring and communicating safety of medicines use in pregnancy and breastfeeding: validated and regulatory endorsed workflows for fast, optimised evidence generation), funded by European Union, Horizon 2020 Programme (call H2020-JTI-IMI2-2017-13-two-stage). Grant Agreement num. 821520; https://www.imi-conception.eu/.
Nina Nauwelaerts received a PhD scholarship by Research-Foundation-Flanders (1S50721N)