International journal of health sciences
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Quantitative determination of a Mesalazine using reversed phase high- performance liquid chromatography (RP-HPLC)
Get PDFMesalazine was quantified in a fast, accurate and sensitive way using reversed-phase high-performance liquid chromatography (RP-HPLC) method. In this method, a separation column of porous silica particles L10 (300 × 4.6mm) was used, the flow rate is 0.8 ml/min, the column temperature is 25 °C, the reagent wavelength is 230 nm, and the injection volume is 20 μl. As for the mobile phase, it consisted of acetonitrile 10% 0.1 and phisphoric acid 0.1% and 90% water and the pH was 4. The method was validated by calculating the recovery that ranged between (95.0457-102.280%), and the correlation coefficient (0.9991) and linearity (20-160 μg/ml).The method was successfully applied for the quantitative determination of the mentioned drug
Relationship between IL-20 and diabetic nephropathy in AL Anbar governorate
Get PDFBackground: Diabetic syndrome is characterized by increase blood sugar and resistance to insulin. It is linked to macrovascular and microvascular complication such as nephropathy, neuropathy, and retinopathy. The aim of this study to investigate the relationship between Interleukin 20 and diabetic nephropathy. Material and Methods: The study was include 36 of them with type 2 diabetes, 23 of them with diabetic nephropathy, and 25 healthy controls population , all of whom were over the age of 40. ELISA was used to calculate the Interleukin 20 concentration. fasting serum sugar, Glycated Hemoglobin, Urea, Creatinine, Total protein, Albumin, and globulin were all found. Body mass index was also calculated. Result: this study shown that decrease level of Interleukin 20 and chronic kidney disease patient comparing to Healthy controls group , and this also associated with increase in fasting serum sugar , Glycated Hemoglobin , Urea , Creatinine and body mass index in patients group compared to Healthy controls group. Conclusion: serum Interleukin 20 level show significance difference between patients and Healthy controls groups. that’s lower in patients groups
Body mass index and glucose level among type 2 diabetic patients
Get PDFBackground and Aim: Diabetes is a metabolic disorder that can affect nearly all organ systems in the body. Obesity and insulin resistance are risk factors for type II diabetes; while the amount of insulin the body produces in obese people is normal, it may not be enough to meet the body's needs. The study aimed to compare glycosylated hemoglobin among obese and non-obese diabetic patients. Method and Material: A case-control study design was conducted on (80) type II diabetic patients who attended Al-Wafaa Specialized Centre for Diabetes and Endocrinology by purposive sampling at Mosul city in Northern Iraq for a period extended from 25th December 2021 to 10th February 2022. The estimation of HbA1c was done by using BS230 Mindray. Results: Patients with type II diabetes who are obese exhibit a considerable rise in HbA1c levels, with a mean of (9.50 ± 1.90) compared to (8.10 ± 1.90) in non-obese type II diabetic patients at P-value = 0.002 (t-test =3.191). Conclusions: The HbA1c levels are higher in obese type II diabetes patients than in non-obese diabetic patients
A relationship of contactin-1 with a number of trace elements in Iraqi rheumatoid arthritis patients with and without COVID-19
Get PDFBackground: Anti-inflammatory intermediaries like contactin-1 (CNTN-1) play an essential role in regulating several diseases, such as Rheumatoid Arthritis (RA). This paper explores the relationship between CNTN-1 and a number of trace elements in RA patients with and without COVID19. Accordingly, it investigates whether there are any correlations between CNTN-1 and some trace elements. Materials and Methods: The paper involved 56 patients, where 28 suffer from RA without any complications, the other 28 have RA with COVID19 attending Al-Fallujah teaching hospital and 28 healthy persons matching in age, sex and ethnic background as control group. Serum level of contactin-1 was estimated by ELISA technique while Uric acid, urea, creatinine, lipid Profile, zinc, copper, ferrous and magnesium were assessed by colorimetric enzymatic methods. Results: The results demonstrated that Contactin-1 serum concentrations had existed more significantly in patients with and without COVID19. However, RA patients and RA with Covid-19 patients showed lower levels of magnesium (Mg), zinc (Zn), iron (Fe) and Fe/Cu ratio. High serum concentrations of CNTN-1 have been identified and associated positively with ESR and Cu/Zn, while serum concentrations of CNTC-1 were positively related with total cholesterol (TC), triglycerides (TG), copper (Cu), zn and iron (Fe)
Evaluating Galectin-3 (LGALS3) +191 gene variant and serum Galectin-3 levels in Egyptian children with familial mediterranean fever
Get PDFBackground: The most important and devastating complications of Familial Mediterranean fever (FMF) is renal amyloidosis, usually affecting the kidneys leading to end stage renal failure. FMF- related renal amyloidosis needed to be diagnosed early. Optimal colchicine dose is effective in prevention and reversing renal amyloidosis. Aim of the work: to evaluate serum galectin-3 level and its gene polymorphism (LGALS3 191 C>A) as a marker of proteinuria and subclinical inflammation in Egyptian children and adolescents with FMF. Methods: Fifty FMF patients in attack free period and 40 healthy children were included as a control group. Serum levels of galectin-3 were measured, Galectin-3 (LGALS3) c.191 C>A (rs4644) gene variant was investigated and morning spot urine was collected for determination of albumin / creatinine ratio (ACR). Results: Serum Galectin-3 levels were significantly higher in FMF patients than control group, P < 0.03. Regarding genotype and allele distribution of (LGALS3) c. 191 C>A polymorphism there was statistical significant difference between cases and control, 13 patients (42%) had CC and the remaining 37 patients (63%) were CA. The control had 18 child (58%) with CC compared to 22 child with CA (37%) and BUN level was higher among CC type of Galectin-3 (LGALS3) c.191 C>A
Hernioplasty technique in wound complications prevention
Get PDFBackground: The issues of prevention of wound complications in the surgical treatment of postoperative ventral hernias (POVG) remain relevant due to the increase in the number of surgical interventions on the abdominal organs and the development of postoperative ventral hernias in the aftermath. Despite the large number of proposed hernioplasty techniques for postoperative ventral hernias, the rates of wound complications remain high. The use of synthetic materials did not provide a reduction in the amount of infection in the area of surgical intervention. In this connection, the improvement of surgical treatment of patients with postoperative ventral hernias, aimed at the prevention of wound complications, is becoming even more relevant. Wound complications prevention in the surgical treatment of postoperative ventral hernias remains relevant due to the increase in the number of operative abdominal interventions. Therefore, improving surgical rehabilitation of patients in the postoperative period in order to minimize wound complications acquires special practical importance. 
Determining new anthropometric markers for screening T2DM in Jaipur, India: A cross sectional study
Get PDFWHO has estimated expected cases of T2DM to rise to 57.2 million by the year 2025 and 80.9 million by the year 2030. Since past two decades there has been constant marked increase in the prevalence of diabetes in urban population of India with noticeable rise in southern part of India. The Prevalence of T2DM ranges from 10-16 % from region to region. The primary objective of the study was to determine the association between Indices using height, waist, hip, thigh, arm, and wrist circumference (cm) with development of T2DM and compare it to existing markers in test subjects and assessing their feasibility as predictive indicators for the development of T2DM. In a cross-sectional study, a total of 605 subjects were involved in the study which included health centers and health camps in Jaipur, India. The study duration was of 1 years (December 2019 to November 2020). Height-to-waist ratio (HtWR), ABI (Arav Body Index), Thigh to waist ratio (TWR) and Wrist to arm ratio (WAR) was compared to common existing markers such as WHtR, WHR and BMI. 
Management of formative research at the university: A systematic review
Get PDFThe study that aims to analyze the management stages developed by universities for formative research and systematize the information captured in various articles that were published between the years 2017 to 2022, in reference to the management of formative research carried out by universities in Latin America. For its development, the PRISMA method and the bibliographic analysis that allowed selecting and identifying those articles that are useful for the study being a total of 30. The results found indicate a low quality of management in planning, execution, evaluation, control, and continuous improvement developed by universities, due to the limited amount of financial, technological, and specialized professional resources. which restricts the disclosure of the results of the research in the main scientific journals in the world, so it is necessary to implement methods and improvements in management that allow these results to be reversed and to be able to reach the level of the number of studies that are published by Asian or European countries
Implementation of the protection and placement of Indonesian workers abroad based on Law NO. 39 year 2004
Get PDFThe purpose of this research is to find out: (1). Protection and placement of Indonesian Migrant Workers Abroad according to Law no. 39 of 2004. (2). The obstacles faced in the protection of Indonesian Migrant Workers Abroad by the Provincial Service Center for Placement and Protection of Indonesian Migrant Workers (BP3TKI) - Banten. (3). Efforts in the protection of Indonesian workers Abroad carried out by the Center to provide Placement and provide Protection of Indonesian Migrant Workers. This research method uses a sociological juridical qualitative approach. The type of data used is secondary and primary data. Techniques for collecting study documentation, interviews, and field surveys. The results of the study obtained the following conclusions: (1). Legal protection of the rights of Indonesia workers, who have not worked well in their work, lack of legal direction, and Eliminate the sense of security while abroad. (2). Obstacles in the implementation of legal protection for workers, there are mistakes he did, namely not reporting to the Indonesian government where he worked, and relatively low education. (3). BP3TKI seeks to hold a job fair, which can be expected to be a vehicle for communication between job seekers and companies that supply jobs abroad
Phytochemical investigation of Solidago Canadensis L. and its activity against Colorectal Adenocarcinoma and acute monocytic leukemia
Get PDFDue to the increase in cancer cases worldwide, natural products are gaining interest, particularlythose herb-based extractsare growing. Plants are classified as one of the primary suppliers of bioactive components. The species Solidago Canadensis, Asterales, Asteraceae, and Plantae are found in Iraq. The upper parts of these plants are very often utilized to treat inflammatory disorders. S. Canadensis L. has been extracted as phytochemical compounds for anti-colorectal adenocarcinoma and -acute monocytic leukemia (AML) in in-vivo cancer models to find novel sources of the anticancer mixture.The relationship between each investigation is one of the critical phases for the effects associated with this particular style of study. In the present research, extracted phytochemical compounds from S. Canadensis L. were discovered to significantly inhibit colorectal adenocarcinoma and AML in vitro, and the narrative makes this compound promising for antitumor activity testing in vivo