International journal of health sciences
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Antioxidant and antipyretic studies on methanolic extraction of flaveria trinervia leaves
Get PDFThe aim of the present study was to perform antipyretic and antioxidant activity of Flaveria trinervia Methanolic leaves extract by different in-vivo and in-vitro models. The different pharmacognostical parameters were evaluated as per standard procedure. Finally, antipyretic (Brewer’s Yeast Pyrexia model) and antioxidant activity (Hydroxyl Radaical scavenging activity, determination of Reducing Power, Metal chelating activity, Carbon tetrachloride (ccl4) induced lipid peroxidation, Inhibitory Test on Protein Oxidative Modification, Lipid peroxidation assay, Catalase assay and Reduced glutathione assay) was evaluated by adopting different methods. The extracts showed a marked antipyretic effect by causing a reduction in yeast-induced fever. Methanolic extract (200 and 400 mg/kg) showed the effect to the same degree as paracetamol (50mg/kg, i.p.). The experimentally induced laboratory model was employed in evaluating the antipyretic activities of Methanolic extracts of Flaveria trinervia. The extract caused a better hypothermal activity against yeast-induced pyrexia in rats. Free radical scavenging activity of Flaveria trinervia. was found because polyphenolic compounds present in plant contribute significantly to the total antioxidant capacity of the leaves. Flavonoids play some important pharmacological roles against diseases, such as cardiovascular diseases, cancer, inflammation and allergy. 
Study of some haematological and immunological parameters in patients infected with giardia lamblia in Najaf Governorate
Get PDFThe current study aimed at finding the relationship between infection of Giardia lamblia and some hematological (complete blood count, concentration of ferritin) and immunological parameters (interleukin-6, interleukin-10), The present study was carried out from June, 2020 to May, 2021. A total of 509 out suspected patients samples and 50 healthy persons , whom have meant the laboratory of AL-Hakeem hospital ,Al Sader General Hospital ,AL-Zahra maternity and pediatrics and Al Furat General Hospital in AL-Najaf province.The results of the current study showed a high incidence of injuries among the age group (10-20) As the percentage (52.06%) , While the lowest rate of infection was in the age group (51-60) As the percentage (37.52%),The results of the current study showed a clear decrease in most of the blood parameters in people infected with the parasite Giardia lamblia Compared to the healthy group While the results showed an increase in eosinophilic blood cells in patients infected with the parasite Giardia compared to the healthy group, Result of study revealed that concentration of (IL-6) in male and female patients infected with G. lamblia were significant decrease (P (211.92±13.07pg /ml), (263.75±21.73) respectively in compared to the control group (481.54±19.83pg /ml), (394.66±32.98pg/ml) respectively
The use of high-performance liquid chromatography technique for the simultaneous determination of amlodipine and valsartan
Get PDFThis technique was used in the estimation of amlodipine and valsartan simultaneously. The method was sensitive and accurate, and the estimation was done in a short time. In this work, a separation column of type L1, 150 mm was used to separate and sold. The group also found the ultraviolet spectrophotometer that used a wavelength of 239 nm, the temperature of the column was 40 degrees Celsius, and the mobile phase, consisting of 50:50 (acetonitrile: methanol: drops of triethylamine, pH = 2.4) was long. Through what was reached, we find that the method is sensitive, accurate and medium in size (101.43-99.13) and (100.17-99.53), and linear punches (6-14 mcg/ml) and (48-112 mcg/ml) for the two drugs, respectively. The method was applied to a number of pharmaceutical preparations available in the local market, successful in the real-time quantification of amlodipine and valsartan, respectively
Study of the impact of civil waste on the chemical, physical and biological content of the Tigris River within Samarra
Get PDFThis study included the selection of three stations, two of which are on the Tigris River passing through Samarra and the other station representing the household wastewater - Samarra, and the duration of the study was six months from October 2021 to March 2022. The study included knowledge of the chemical, physical and biological properties of the domestic wastewater plant and river water and the observation of domestic wastewater on the water quality of the Tigris River. Chemical agents included pH, dissolved oxygen, and the bio requirement of oxygen, while physical factors included air temperature, water temperature and total dissolved salts. Results showed that pH values tended to be base, ranging from 6.6 - 8.7, dissolved oxygen showed converging values ranging from 3.8-9 mg/L, and the bio-oxygen requirement values ranged from 0.8-8 30 mg/L, the air temperature ranged from 7-32°C, the water temperature ranged from 5-26°C, and the total melt salt values ranged from 210°C - 1380 mg/L, total number of air bacteria (TPC) ranged between (0.06 – 74000*) cell/mL
Integration of technological pedagogical content knowledge (TPACK) in classrooms through a teacher's lens
Get PDFTechnological literacy has become an unavoidable requirement in today's classroom. The importance of incorporating technology into traditional learning settings aims to create meaningful learning experiences while also cultivating positive perspectives and relationships with technology. While technological knowledge has become indispensable in most classrooms and has been incorporated into various curriculum and frameworks, the incorporation of technology in traditional teaching is accompanied by barriers and limitations based on preconceived notions of technology, school culture, and access to technology. This paper attempts to assist teachers/educators in understanding how Mishra and Koehler's Technology Pedagogical Content Knowledge (TPACK) model can resolve issues and help them overcome the monotony of the online teaching-learning process. The goal of this paper is to provide a brief overview of the TPACK model, examples of how the framework can be integrated with science content, and recommendations for solutions to common barriers and limitations across other subject areas
Influence of section 377 on relationships of the MSM community with their family members
Get PDFBackground: Sexual and gender minorities all over the world are heavily impacted by the attitudes and beliefs of those around them. With this study, the researcher is trying to explore the impact of Section 377 (2018 judgment) on the relationships between the Men who have Sex with Men (MSM) and their parents. Method: This qualitative study was completed using semi-structured interviews that were conducted with 11 MSM who were living in Delhi and had come out to their parents. Additionally, interviews were also conducted with 5 parents of the selected MSM Community members. Qualitative content analysis was used to examine the data. Five major themes were identified; awareness of one’s sexual orientation, relationship dynamics with parents before coming out, disclosure of MSM identity to parents, change in relationship with parents post coming out and parent’s response and support towards their son’s sexual orientation. Results: During their adolescent or early adulthood years, the selected group of MSMs became certain of their sexual orientation. During the age range of 15-23 years, all MSM participants reported disclosing their sexual identity to their parents. 
Meta-analysis: The effect of kangaroo mother care on growth (increasing length gain) in infants with low birth weight
Get PDFThis study aimed to o analyze the effect of kangaroo mother care on length gain in low birth weight (LBW) infants. This study is a systematic review and meta-analysis. The articles used in this study were obtained from three database, namely PubMed, Science Direct, and Google Scholar. The articles included are full-text article with a study design of randomized controlled trial from 2013 to 2022. Articles were analyzed using the Review Manager 5.3 application. Result: A total of 11 articles from Asia continent (India, Bangladesh, Philipina, and Nepal). The data collected showed that kangaroo mother care increased growth (length gain) of LBW infants 0.21 times and was statistically significant (SMD= 0.21; CI 95%= 0.19 hingga 0.22; p < 0.001). Conclussion: Kangaroo mother care increases length gain in LBW babies
Assessment of liver function enzymes, MDA and GSH in the Sera of COVID-19 patients
Get PDFA cluster of unexplained pneumonia cases was reported in Wuhan, China, in late December 2019. A new coronavirus was identified as the causative cause of this mysterious pneumonia a few days later. The World Health Organization has temporarily given this causal virus the designation of severe acute respiratory syndrome coronavirus 2 and the related infected disease as coronavirus disease 2019 (COVID-19). The primary objective of this study is to examine the liver efficiency and assess the oxidative stress status of COVID-19 patients by measuring liver function enzymes, glutathione and MDA. The study included 120 cases ranging from 20 to 60 years, divided into three groups, COVID-19 patients, recovered, and control groups. Group. The results obtained indicated a significant increase in ALT, AST, and ALP activity (p< 0.01) in patients compared to those recovering and control. The results also indicated a significant increase in MDA in contrast to a significant decrease in the GSH activity of COVID-19 patients compared to recovered and healthy subjects. These results reflect the strong relationship between COVID-19 and impaired liver function as well as impaired oxidative stress / antioxidant balance
Risk factors for iron-deficiency anemia in infants aged 6-12month old
Get PDFBackground: Even though the frequency of iron deficient anemia has declined in the last years, It has been the most prevalent nutritional deficit in the world. Objective: To evaluate the prevalence and etiology due to iron shortage anemia in 6- to 12-month-old babies. Patients and method: This study is a hospitalized-based study performed in a central teaching hospital in Baghdad, from 1st March 2021 to 1st February 2022, to assess the incidence also underlying causes of IDA in infants between six months and 12m of age. full history was taken from the mothers, an assessment of nutritional status done to all cases. Infants (n=133) had their mean corpuscular volume, hemoglobin, Evaluation of serum ferritin, serum iron, also total iron-binding capability. Anemia was defined as hemoglobin levels below 10.5 g/L, serum ferritin levels below 12µg/L, then iron deficiency as ferritin levels also mean corpuscular volume below 74 fL, respectively, or serum iron below 9µmol/l and TIBC more than 50µmol/l. Results: Iron deficiency prevalence was 27,3 percent and iron deficiency anemia prevalence were 24,2 percent. Less than 3000 grams at birth was the most significant risk factor for iron insufficiency (P<0.0001). 
RP-HPLC analytical method development and validation of obeticholic acid in bulk and marketed formulation
Get PDFThe purpose of this study is to develop a new analytical RP-HPLC method for quantifying Obeticholic Acid in bulk and commercial formulations. Liquid chromatography is performed on a C18 column and the mobile phase is prepared using 0.1% orthophosphoric acid and acetonitrile in a ratio of 65:35. The flow rate was 1.0 ml / min and the injection volume was 10 ml. The maximum absorption of the drug was 210 nm. The retention time was found to be 2.80 minutes. This method was found to be accurate and linear with a correlation coefficient of 0.999 in the range 2.4-14 mg / mL. The percentage RSD for accuracy was less than 1.8%, averaging 100.05%. All validation parameters were statistically validated according to ICH guidelines and were within acceptable criteria. This method turned out to be simpler, more accurate, more specific, more accurate and more robust. This HPLC method is used for the analysis of obeticholic acid