Online Journal Faculty of Medicine Universitas Sriwijaya
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PREVALENSI PENDERITA KATARAK DENGAN DIABETES MELITUS DI RS SRIWIJAYA PALEMBANG TAHUN 2019
No full textAbstract
Prevalence Of Cataract Patients With Diabetes Mellitus In Sriwijaya Palembang Hospital 2019.Cataracts are opacities that occurs in the eye lens and thus block light entering the eye. Indonesia's population has a tendency to suffer cataracts 15 years sooner than the population in the subtropics. Approximately 16-22% of cataract surgery patients under 55 years old. Patients with diabetes mellitus 4.9 times higher risk of developing cataracts. Data from the Ministry of Health in 2014 said that the prevalence of cataract in the province of South Sumatra in 2013 was recorded at 1.7%. Research shows 31.4% of cataract patients with diabetes mellitus. This study aimed to determine the prevalence of cataract patients with diabetes mellitus in hospital Sriwijaya Palembang in 2019.This research is a descriptive survey method. The study population was all patients with cataract were hospitalized in the Hospital Eye Clinic Sriwijaya many as 494 and as many as 101 used as a sample with a total sampling technique. Observed data from medical records of patients in hospital medical record Installation Sriwijaya period of January - September 2019.The results showed that cataract patients with diabetes mellitus, the most suffered by women were 60 (60.4%), age group 56-65 years (39.6%), history of diabetic retinopathy NPDR types of 7 people (6.9% ), the type of PDR of 4 people (4.0%), postoperative visual acuity of cataract with good category 57 (56.4%), while 20 (19.8%), and worse 24 (23.8%).
The prevalence of cataract patients with diabetes mellitus in hospital Sriwijaya Palembang in 2019 amounted to 20.44%.Abstrak
Katarak merupakan kekeruhan yang terjadi pada lensa mata sehingga menghalangi sinar masuk ke dalam mata. Penduduk Indonesia memiliki kecendrungan menderita katarak 15 tahun lebih cepat dibandingkan penduduk di daerah subtropis. Sekitar 16-22% penderita katarak yang dioperasi berusia dibawah 55 tahun. Penderita diabetes melitus berisiko 4,9 kali lebih tinggi untuk menderita katarak. Data dari Departemen Kesehatan tahun 2014 menyebutkan bahwa prevalensi katarak di propinsi Sumatra Selatan pada tahun 2013 tercatat sebesar 1,7%. Penelitian menunjukkan 31,4% penderita katarak menderita diabetes melitus. Penelitian ini bertujuan untuk mengetahui prevalensi penderita katarak dengan diabetes melitus di RS Sriwijaya Palembang tahun 2019. Penelitian ini merupakan penelitian deskriptif dengan metode survei. Populasi penelitian merupakan seluruh penderita katarak yang di rawat inap di poliklinik mata Rumah Sakit Sriwijaya Palembang sebanyak 494 dan sebanyak 101 digunakan sebagai sampel dengan teknik total sampling. Data diobservasi dari rekam medis pasien di Instalasi Rekam Medik RS Sriwijaya Palembang periode Januari - September 2019. Hasil penelitian menunjukkan bahwa penderita katarak dengan diabetes melitus paling banyak diderita oleh perempuan sebanyak 60 orang (60,4%), kelompok umur 56-65 tahun (39,6%), riwayat retinopati diabetik tipe NPDR sebanyak 7 orang (6,9%), tipe PDR sebanyak 4 orang (4,0%), tajam penglihatan pascaoperasi katarak dengan kategori baik 57 orang (56,4%), sedang 20 orang (19,8%), dan buruk 24 orang (23,8%).
Prevalensi penderita katarak dengan diabetes melitus di RS Sriwijaya Palembang tahun 2019 sebesar 20,44%
Ratio of Inter Canthal Distance to Mesiodistal Width of Upper Anterior Teeth of the Upper Jaw Between Batak and Minangkabau Tribe
No full textIntroduction. Indonesia is rich in diversity of ethnic groups, each of which has its own characteristics, including the Batak and Minangkabau tribes. One of these characteristics can be seen from the intercanthal distance and mesiodistal width of the six maxillary anterior teeth. This research was aimed to determine whether there is a difference in the ratio of the intercanthal distance to the mesiodistal width of the six maxillary anterior teeth between the Batak and Minangkabau tribes.
Methods. This research is analytic observational with nonexperimental correlation design. The research subjects were 60 people with the subject inclusion criteria were aged> 17 years. The intercanthal distance was measured from the median angle of the right eye to the left in the study subjects. Mesiodistal width measurements of six maxillary anterior teeth were performed in the study model, measured from the mesial to the widest distal margin of each tooth. Both measurements were carried out using a digital caliper with three repetitions. Data were analyzed using Pearson correlation test and independent t-test.
Results. The results showed a significant (p> 0.05) and strong relationship between the intercanthal distance and mesiodistal width of the maxillary anterior six teeth in both tribes. The results of the independent t-test showed that there was a significant difference between the two tribes (p <0.05) with the mean value of comparison in the Batak tribe 1:1.42 and the Minangkabau tribe 1: 1.45.
Conclusion. There was a significant difference in the ratio of the intercanthal distance to the mesiodistal width of the six maxillary anterior teeth between the Batak and the Minangkabau
Korelasi Ekspresi CD47 terhadap Faktor-Faktor Klinikopatologi pada Karsinoma Ovarium: -
No full textOvarian carcinoma is the fourth most common cause of death in gynecological malignancies. CD47 is asurface protein widely expressed on many benign and malignant cells, including ovarian carcinoma. This study wasaimed to identifythe correlation between CD47 expression with clinicopathological factors inovarian carcinoma.Case series studies was undertaken started on January 1, 2016 to October 31, 2019 at Department of Anatomic Pathology Faculty of Medicine Sriwijaya University/Mohammad Hoesin Hospital, Palembang. Fifty cases, consisting of LGSC, HGSC, MC, EC, CCC, each 10 cases were selected. The slides were stained with anti-CD47 antibody. The correlation of expression of anti CD47 protein with ages, clinical stages and CA125 serumwere analysed byGamma test. The correlation of expression of anti CD47 protein with histopathologic subtypes and chemotherapeuticresponses were analyzed using Contingency test.There was no significantcorrelation between CD47 expression with ages (p=0.130), histopathological subtypes (p=0,956), FIGO clinical stages (p=0.459), CA125 serum level (p=0.366) and chemotherapeutic response (p=0.129).Althoughthere was no significant correlation between CD47 expression and clinicopathological characteristics,atendency that the higher expression CD47 will be followed by the younger age groups, higher clinical stagesand higher CA125 serum was observed.Kanker ovarium adalah keganasan ginekologik yang paling mematikan merupakan peringkat keempat di dunia pada kematian wanita penderita kanker.Cluster of differentiation 47(CD47) merupakan sebuah protein sel permukaan yang terekspresi di banyak seljinak dan maligna, termasuk karsinoma ovarium.Penelitian ini bertujuan untuk mengetahui korelasi ekspresi CD47 terhadap faktor-faktor klinikopatologi padakarsinomaovarium.Penelitianserial kasus dengan populasipenelitianadalahkasus LGSC, HGSC, MC, ECdanCCCyang tersimpan di Departemen/BagianPatologiAnatomi RSUP Dr. MohammadHoesin Palembang periode 1 Januari 2016 sampaidengan 31 Oktober 2019. Jumlahsampel 50 kasus, masing-masing sebanyak 10kasussubtipe histopatologi. Slaiddilakukanpulasanimunohistokimiamenggunakanantibodi anti CD47 klon B6H12. Analisis korelasi ekspresiCD47 terhadap usia, stadium klinis dan kadar CA125 dianalisismenggunakanujiGamma. Analisis korelasi ekspresi CD47 terhadap subtipe histopatologi dan respon kemoterapi menggunakan uji Contingensi. Tidak terdapatkorelasi bermakna antara ekspresiCD47 terhadap usia (p=0,130), subtipe histopatologi (p=0,956), stadium klinis FIGO (p=0,459), kadar CA125 (p=0,366) dan respon kemoterapi (p= 0,129).Penelitian ini menemukan bahwa tidak ada korelasi yang bermakna antara ekspresi CD47 yang tinggi dengan faktor-faktor klinikopatologi pada karsinoma ovarium, namun ada kecenderungan semakin tinggi ekspresi CD47 semakin muda kelompok usia, semakin lanjut stadium klinisdan semakin tinggi kadar CA125
HUBUNGAN ANTARA CITRA TUBUH DAN TINGKAT HARGA DIRI PADA SISWI SMA FONS VITAE I TAHUN AJARAN 2019/2020
No full text. Many teenagers who experience dissatisfaction with changes in body shape. Mismatched the reality of actual body shape and ideal body image perception triggers negative body image perception which can cause a decrease in self-esteem. In terms of gender, women's self-esteem levels tend to be lower compared to men. This study was an observational analytic study with a cross-sectional approach, taken at Fons Vitae I Senior High School with stratified random sampling. The body image was measured by using Body Shape Questionnaire-34 (BSQ-34) and self-esteem was measured by using Rosenberg Self Esteem Scale (RSES) questionnaire. Data are analyzed using chi-square. The total respondents were 109 female students. In univariate analysis there were 13.8% female students who had dissatisfaction with her body image and 86.2% female students who had satisfaction with her body image. Female students with low self-esteem were 19.3% and high self-esteem were 80.7%. The bivariate analysis shows that there is a significant association between body image and the level of self-esteem among Senior High School female students at Fons Vitae I (p = 0.039) with OR = 3.511. There is a significant association between body image and level of self-esteem.Banyak remaja yang mengalami ketidakpuasan terhadap perubahan bentuk tubuh. Tidak sesuainya kenyataan bentuk tubuh aktual dan persepsi citra tubuh ideal memicu persepsi citra tubuh negatif yang dapat menyebabkan penurunan harga diri. Dalam hal jenis kelamin, tingkat harga diri perempuan cenderung lebih rendah dibandingkan dengan laki-laki. Penelitian ini merupakan penelitian observasional analitik dengan pendekatan cross sectional, yang dilakukan di SMA Fons Vitae I dengan stratified random sampling. Citra tubuh diukur dengan menggunakan Body Shape Questionnaire-34 (BSQ-34) dan harga diri diukur dengan menggunakan kuesioner Rosenberg Self Esteem Scale (RSES). Data dianalisis dengan metode potong lintang, menggunakan uji chi square. Total responden adalah 109 siswi. Pada analisis univariate terdapat 13,8% siswi yang memiliki ketidakpuasan terhadap citra tubuhnya dan 86,2% siswi yang memiliki kepuasan terhadap citra tubuhnya. Siswi yang memiliki harga diri rendah adalah sebesar 19,3% responden dan harga diri tinggi adalah sebesar 80,7%. Analisis bivariate menunjukkan bahwa terdapat hubungan yang bermakna antara citra tubuh dan tingkat harga diri pada siswi SMA Fons Vitae I (p = 0,039) dengan OR sebesar 3,511. Terdapat hubungan yang bermakna antara citra tubuh dan tingkat harga diri
mRNA NFATC1 Expression in Genu Osteoarthritis with Effusion
No full textBased on a study conducted by the WHO Global Burden of Disease in 2010 stated, OA ranks11th, the cause of disability in the world, and ranks 6th in East Asia and the Asia-Pacificcountries, ranked 10th in North America, ranked 7th in Eastern Europe , and ranked 13th inWestern Europe. Pathogenesis of osteoarthritis (OA) as degenerative joint disease that was oncethought caused by a mechanical process. The prevalence, etiology, pathogenesis and progressionof OA are still not understood until now, mainly because of the many influencing factors. Thistype of research is a analytic study. It was conducted in Rheumatology Polyclinic Dr.Mohammad Hoesin Palembang from February to December 2019. Affordable researchpopulation is all genu osteoarthritis sufferers with effusion who go to Dr. RSUP MohammadHoesin Palembang as 80 samples. Comparison of NFATC1 mRNA levels in genu osteoarthritispatients with effusion shows that there is no difference in gender and history of diabetes, whereashypertension history and degree of osteoarthritis based on Lawrence Kalgren shows significantlydifferent expression of NFATC1 mRNA. Age with NFATC1 mRNA expression showed nosignificant correlation, in contrast to BMI, Stroke Test and joint effusion volume showed a weaksignificant correlation, even though the direction of the correlation was negative on Stroke Testand joint effusion volume
Hubungan Panjang Jari Telunjuk Tangan (Digiti II Manus) Terhadap Tinggi Badan Pada Suku Batak Di Fakultas Kedokteran Universitas Muhammadiyah Sumatera Utara
No full textThere are several accidents when the bodies of victims from natural disasters or disaster from human error cannotbe identified because of severe damage and only be found a few parts of the body. The estimated length of the body can be done by measuring a certain part of body to estimate height. The regression formula using the length of the index finger of the hand, age and sex has been proofed as valid estimate of the height and is useful in clinical context. The aim of this study wasto determine the relation of middle finger length to stature of Bataknese at the Faculty of Medicine Universitas Muhammadiyah Sumatera Utara (UMSU). This study was a descriptive correlative study with cross-sectional design. The population was students, permanent lectures, and education staffs from Bataknese at the Faculty of Medicine UMSU who had completed the inclusion and exclusion criterias. The sampling technique used total sampling method with the total subject was 63 people. Index finger length was positively and significantly correlated to stature with coefficient correlation ranging from 0.611 to 0.681 (p<0.001). Linear regression equations were showing Standard Error of the Estimate (SEE) ranging from 2.883 to 3.3839 (p<0.001). There was significantly relation of index finger length to stature with strong and very strong correlation, so the stature can be estimated by measuring index finger length with linear regression equation.Ada beberapa kejadian dimana jenazah para korban bencana alam atau bencana akibat kesalahan manusia tidak lagi dapat diidentifikasi karena telah terjadi kerusakan yang parah seperti hanya ditemukannya beberapa bagian potongan dari tubuh. Pada jenazah yang tidak utuh, perkiraan panjang jenazah dapat dilakukan dengan mengukur bagian tertentu tubuh jenazah untuk memperkirakan tinggi badan pada saat masih hidup. Formula persamaan regresi menggunakan panjang jari telunjuk tangan, usia dan jenis kelamin valid untuk memprediksi tinggi badan. Penelitian ini bertujuan untuk mengetahui hubungan panjang jari telunjuk tangan (Digiti II manus) terhadap tinggi badan pada suku Batak di Fakultas Kedokteran Universitas Muhammadiyah Sumatera Utara (UMSU). Rancangan penelitian ini adalah analitik korelatif dengan pendekatan cross-sectional. Subjek penelitian sebanyak 63 orang suku Batak di Fakultas Kedokteran UMSU yang terdiri dari laki-laki dan perempuan yang memenuhi kriteria inklusi dan eksklusi. Teknik pengambilan sampel menggunakan metode total sampling. Panjang jari telunjuk tangan memiliki korelasi yang positif dan signifikan terhadap tinggi badan dengan koefisien korelasi yang berkisar antara 0,611 hingga 0,861 (p<0,001). Persamaan regresi linear yang didapatkan menunjukkan Standard Error of the Estimate (SEE) 2.883 hingga 3,839 (p<0,001). Terdapat hubungan yang signifikan antara panjang jari telunjuk tangan terhadap tinggi badan dengan korelasi yang kuat dan sangat kuat, sehingga tinggi badan dapat diperkirakan menggunakan ukuran panjang jari telunjuk tangan melalui persamaan regresi linear
The Relationship Between Smoking Status And Diabetic Foot Severity
No full textDiabetes mellitus is a chronic metabolic disease which happens to be the 7th leading cause of death worldwide. In Indonesia, 6.9% of population aged ³ 15 years old suffers from this disease. Diabetic foot is one of the complication of diabetes mellitus which has high mortality and morbidity level. Smoking is an addictive behavior that is really common in Indonesia. Components inside a cigarette, such as nicotine, can contribute in determining the prognosis of diabetic foot through various mechanism. This study aims to investigate the association between smoking status and the severity degree of diabetic foot. This study is an observational analytic study using a cross-sectional approach. Data collection was conducted on January 2019 until July 2019 in RSUK Pesanggrahan and Atma Jaya Hospital Jakarta. The research data was obtained through interviews with diabetic foot patients and medical record reading. Data was analyzed using the chi-square method. There were 40 patients eligible to be the subject of this study. The smoker status with the most distribution was moderate smoker (27.5%) and severity degree of diabetic foot with most distribution was Wagner 3 (25%). Bivariate analysis showed that there was a significant association between smoking status and severity degree of diabetic foot (p < 0.001). In conclusion, there is a significant association between smoking status and the severity degree of diabetic foot. Therefore, education regarding the importance of smoking cessation to diabetic foot patients should be done in order to improve the prognosis of diabetic foot patients.The Association Between Smoking Status and Severity Degree of Diabetic Foot. Diabetes mellitus is a chronic metabolicdisease which happens to be the 7 th leading cause of death worldwide. In Indonesia, 6.9% of population aged 15 yearsold suffers from this disease. Diabetic foot is one of the complication of diabetes mellitus which has high mortality andmorbidity level. Smoking is an addictive behavior that is really common in Indonesia. Components inside a cigarette, suchas nicotine, can contribute in determining the prognosis of diabetic foot through various mechanism. This study aims toinvestigate the association between smoking status and the severity degree of diabetic foot. This study is anobservational analytic study using a cross-sectional approach. Data collection was conducted on January 2019 until July2019 in RSUK Pesanggrahan and Atma Jaya Hospital Jakarta. The research data was obtained through interviews withdiabetic foot patients and medical record reading. Data was analyzed using the chi-square method. There were 40patients eligible to be the subject of this study. The smoker status with the most distribution was moderate smoker(27.5%) and severity degree of diabetic foot with most distribution was Wagner 3 (25%). Bivariate analysis showed thatthere was a significant association between smoking status and severity degree of diabetic foot (p < 0.001). Inconclusion, there is a significant association between smoking status and the severity degree of diabetic foot. Therefore,education regarding the importance of smoking cessation to diabetic foot patients should be done in order to improvethe prognosis of diabetic foot patients
FAKTOR YANG BERPENGARUH TERHADAP KECEPATAN TERJADINYA KATARAK SENILIS DI RS. KHUSUS MATA PROVINSI SUMATERA SELATAN
No full textCataracts are any condition of opacity in the lens that can occur due to the hydration (fluid addition) of the lens, the lens protein denaturation or the consequences of both. Based on the World Health Organization (WHO) data, cataracts can cause blindness in more than 17 million people in the world. Factors that can affect the development rate of opacity of the lens such as diabetes mellitus, hypertension, certain medications, the B ultra violet rays from sunlight, toxic effects of smoking, alcohol, less vitamin E, and chronic inflammation in the eyeball. The type of research used is observational analytical research with cross sectional design. This study was held in August to December in 2019 in RS. Special Eye of South Sumatera province with sampling as many as 234 patients from medical record. Data is processed using SPSS. The Chi-square test is conducted to determine the relationship of factors that affect the rate of senile cataract in RS. Khusus Mata Provinsi Sumatera Selatan. From 234 patients, as many as 177 patients (75.6%) with mature cataract and 57 patients (24.4%) with immature cataract. There is no meaningful relation between senile cataract and hypertension (p = 0,068; OR = 1,084; 95% CI = 0,589-1,995). There is no meaningful relation between senile cataract and diabetes mellitus (p = 1.808; OR = 1,876; 95% CI = 0,741-4,747). There is no meaningful relation between senile cataract and gender (p = 0.51; OR = 0,933; 95% CI = 0,514-1,696). There is no meaningful relation between the senile cataract and age (p = 0,784; OR = 1,319; 95% CI; 0,714-2,437). There is no meaningful relation between senile cataract and hypertension. There is no meaningful relation between senile cataract and diabetes mellitus. There is no meaningful relation between senile cataract and gender. There is no meaningful relation between the senile cataract and age.Katarak adalah setiap keadaan kekeruhan pada lensa yang dapat terjadi akibat hidrasi (penambahan cairan) lensa, denaturasi protein lensa atau terjadi akibat kedua-duanya. Berdasarkan data World Health Organization (WHO), katarak dapat menyebabkan kebutaan pada lebih dari 17 juta penduduk di dunia. Faktor yang dapat mempengaruhi kecepatan berkembangnya kekeruhan lensa seperti diabetes melitus, hipertensi, obat tertentu, sinar ultra violet B dari cahaya matahari, efek racun dari merokok, alkohol, kurang vitamin E, dan radang menahun di dalam bola mata. Jenis penelitian yang digunakan adalah penelitian analitik observasional dengan desain cross sectional. Penelitian ini dilaksanakan pada bulan Agustus sampai Desember tahun 2019 di RS. Khusus Mata Provinsi Sumatera Selatan dengan pengambilan sampel sebanyak 234 pasien dari rekam medik. Data diolah menggunakan SPSS. Dilakukan uji Chi-square untuk mengetahui hubungan faktor yang berpengaruh terhadap kecepatan terjadinya katarak senilis di RS. Khusus Mata Provinsi Sumatera Selatan. Dari 234 pasien, sebanyak 177 pasien (75,6%) menderita katarak senilis matur dan 57 pasien (24,4%) yang menderita katarak senilis imatur. Tidak terdapat hubungan bermakna antara katarak senilis dengan hipertensi (p=0,068; OR=1,084;95% CI=0,589-1,995). Tidak terdapat hubungan bermakna antara katarak senilis dengan diabetes mellitus (p=1.808;OR=1,876;95%CI=0,741-4,747). Tidak terdapat hubungan bermakna antara katarak senilis dengan jenis kelamin (p=0,51;OR=0,933;95% CI=0,514-1,696). Tidak terdapat hubungan bermakna antara katarak senilis dengan usia (p=0,784;OR=1,319;95% CI;0,714-2,437). Tidak terdapat hubungan bermakna antara katarak senilis dan jenis kelamin. Tidak terdapat hubungan bermakna antara katarak senilis dan usia.Tidak terdapat hubungan bermakna antara katarak senilis dan hipertensi. Tidak terdapat hubungan bermakna antara katarak senilis dan diabetes melitus
Efektivitas Pemberian Ekstrak Daun Jati Belanda (Guazuma Ulmifolia Lam) terhadap Kadar CRP pada Tikus Wistar Model Kontusio Pulmonum
No full textGuazuma ulmifolia Lam is a plant with high flavonoid and phenol content. Both of these substances can provide antioxidant effects that are good for the treatment of pulmonary contusions. The aim of the study was to determine the efficacy of Guazuma ulmifolia Lam leaves extract on CRP levels in wistar rats in pulmonary contusion models. In vivo study, pre-post test only has been done in Animal House Faculty of Medicine Sriwijaya University in the period from November to December 2019. There were 25 male Wistar strain rats and divided into five groups, each group consisting of five mice. Mice are induced pulmonary contusions by dropping a load from a certain height. after that, rat blood was taken to be examined for pre-treatment CRP levels. Rats were treated according to the group for 48 hours, then their blood was taken to be examined for post-treatment CRP levels with ELISA. Data was analyzed using SPSS version 25. The rats weight and CRP levels are homogen. Guazuma ulmifolia Lam leaves extract showed significant results in reducing CRP levels in all groups compared with the control group.. The administration of the Guazuma ulmifolia Lam leaves extract (Guazuma ulmifolia Lamk) in rats with pulmonary contusions can reduce serum CRP levels.Daun Jati Belanda merupakan tanaman dengan kandungan flavonoid dan fenol yang cukup tinggi. Kedua kandungan zat tersebut dapat memberikan efek antioksidan yang baik untuk proses pengobatan kontusio pulmonum. Penelitian ini ditujukan untuk mengetahui pengaruh pemberian ekstrak daun jati Belanda terhadap kadar CRP pada tikus wistar model kontusio pulmonum. Penelitian dilakukan secara in vivo. Hewan uji tikus jantan galur Wistar (n=25) dibagi menjadi lima kelompok yang tiap kelompok terdiri dari lima tikus. Tikus diinduksi kontusio pulmonum dengan cara dijatuhkan beban dari ketinggian tertentu, setelah itu diambil darahnya untuk diperiksa kadar CRP sebelum perlakuan. Tikus diberi perlakuan sesuai dengan kelompok selama 48 jam, lalu diambil darahnya untuk diperiksa kadar CRP sebelum perlakuan menggunkan ELISA. Data di analisis menggunakan SPSS versi 25. Pemberian ekstrak daun jati belanda menujukkan hasil yang signifikan dalam menurunkan kadar CRP pada semua kelompok dibandingkan dengan kelompok kontrol. Pemberian ekstrak daun jati belanda (Guazuma ulmifolia Lam) efektif menurunkan kadar CRP.pada tikus model kontusio pulmonum
The Effect of Hydrotherapy in Low Back Pain Patients
No full textBackground: Low back pain (NPB) is the first disease that causes disabilities at all ages, and its incidence increases withage. A number of previous studies have reported that hydrotherapy has an effect on improving low back pain andincreasing flexibility.Therefore, this study aims to determine the effect of hydrotherapy on pain intensity andlumbosacral flexibility in low back pain patients at dr. Mohammad Hoesin Palembang. Methods: This study is a pre-experimental study with a one group pretest-posttest design with a sample size of 35 NPB patients. Inclusion criteriawere NPB patients who did not undergo operative action, had no contraindications to undergo hydrotherapy, andwere > 29 years old. The exclusion criteria were patients with communication disabilities and a history of low backpain due to infection, tumor and metastases. Subjects dropped out of the study if they underwent hydrotherapy lessthan three times or withdrew. Pain intensity and lumbosacral flexibility data were obtained before and after thesubject underwent hydrotherapy once a week for one month. Results: There was a decrease in pain intensity from5.57 to 4.00 (p <0.001) and an increase in lumbosacral flexibility from 48.10 to 48.73 (p = 0.014) in low back painpatients undergoing hydrotherapy. Conclusion: There is an effect of hydrotherapy on reducing pain intensity andincreasing lumbosacral flexibility in low back pain patients undergoing hydrotherapy at the Medical RehabilitationInstallation Dr. Mohammad Hoesin Palemban