Open Journal System Yapenas 21 Maros
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Evaluating the Hepatoprotective Effects of Barley on Alloxan-Induced Liver Damage in Diabetic Male Wistar Rats
No full textType 2 diabetes mellitus often leads to non-alcoholic fatty liver disease, affecting 69-74% of patients. Barley (Hordeum vulgare) offers a potential therapeutic alternative with safer interventions. This study aimed to explore the effects of barley on liver histopathology in alloxan-induced male Wistar rats and compare it with metformin. The research was conducted using a laboratory experimental design with 36 male Wistar rats divided into six groups: normal control, negative control (alloxan induction without treatment), positive control (metformin), and three treatment groups with variations in barley administration. Treatment group 1 received barley before and after alloxan induction, treatment group 2 received barley and standard feed after alloxan induction, and treatment group 3 received standard feed mixed with barley after alloxan induction. Barley was administered for 28 days, and histopathological analysis was performed at the end of the study. Data were analyzed using the Kruskal-Wallis and Mann-Whitney tests. The results showed that barley was able to improve liver cell damage, although not as effectively as metformin. The positive control group with metformin showed an average liver damage score of 148,33 with 53,03% normal cells and 15,28% necrotic cells. In contrast, the barley treatment groups showed average liver damage scores of 169,67 and 159,67. Thus, barley can improve liver histopathology in alloxan-induced rats, highlighting its potential as a safe herbal therapy for preventing and managing liver damage caused by oxidative stress in diabetes mellitus
Analisis Vitamin C dan Seng pada Kue Daun Kelor sebagai Pangan Fungsional untuk Imunitas
No full textCookies merupakan cemilan yang akrab di segala usia. Daun kelor (Moringa oleifera) merupakan pangan lokal tinggi zat gizi, mudah didapatkan dan sangat berlimpah. Daun kelor umumnya diolah sebagai sayur. Perlu menunjukkan kepada masyarakat bahwa daun kelor bisa juga diolah sebagai cookies yang tinggi zat gizi dan bisa menjadi alternatif pangan fungsional. Pemanfaatan cookies daun kelor sebagai pangan tinggi zat gizi merupakan salah satu alternatif pangan fungsional yang bisa memperbaiki imunitas tubuh. Tujuan penelitian ini adalah untuk mengetahui kandungan vitamin C dan Seng dari cookies daun kelor sebagai cemilan tinggi gizi. Penelitian ini adalah penelitian eksperimental murni dengan formula cookies kelor 9%. Kandungan gizi dibandingkan dengan Angka Kecukupan Gizi harian. Hasil penelitian ini menunjukkan bahwa formula cookies berwarna hijau tua, masih ada sedikit aroma khas kelor. Kandungan vitamin C dan seng berturut-turut diperoleh 89,28 mg/100 gram dan 1,99 mg/100 gram cookies kelor
Pengenalan Teknologi Tunnel untuk Produksi Garam di Desa Panimbangjaya Kabupaten Pandeglang
No full textSalah satu potensi sumber daya perikanan dan kelautan di Selat Sunda yang belum dimanfaatkan dengan optimal adalah produksi garam. Padahal kebutuhan garam di pesisir Selat Sunda khususnya di Kabupaten Pandeglang sangat tinggi, khususnya untuk kebutuhan usaha pengolahan ikan. Keterbatasan teknologi dan kapasitas masyarakat untuk dapat memproduksi garam khususnya di Desa Panimbangjaya menjadi kendala utama yang perlu diselesaikan. Kegiatan ini bertujuan untuk meningkatkan kapasitas masyarakat dan introduksi teknologi tunnel untuk memproduksi garam di Desa Panimbangjaya. Introduksi teknologi tunnel garam telah dilakukan pada Bulan Juli 2024 dengan luasan tunnel 80 m² yang dibagi menjadi empat meja kristalisasi. Peningkatan kapasitas kelompok melalui penyuluhan dan pendampingan produksi garam telah dilakukan dan dalam satu siklus dapat menghasilkan garam dengan berat 12 kg per meja kristalisasi. Peningkatan kualitas air baku yang akan digunakan untuk produki garam masih diperlukan sehingga dalam satu siklus diharapkan dapat meningkatkan volume garam yang dihasilkan. Garam yang dihasilkan dapat dimanfaatkan untuk memenuhi kebutuhan garam pada usaha pengolahan ikan asin di Desa Panimbangjaya. Tumbuh dan berkembangnya produksi garam dengan sistem tunnel diharapkan dapat menyediakan lapangan pekerjaan, menumbuhkan pusat ekonomi baru sehingga kebutuhan garam di Desa Panimbangjaya tidak lagi bergantung pada pasokan garam dari Indramayu dan Cirebon
Comparison of Giving Mecobalamin Supplements to Improve the Severity of Painful Diabetic Neuropathy
No full textDiabetic Painful Neuropathy (DPN) is caused by the progressive loss of nerve fibers due to hyperglycemia, oxidative stress, andhomocysteinemia. Mecobalamin supplementation has shown potential in improving peripheral neuropathy symptoms by enhancing nerve conduction and alleviating neuropathic pain. However, its efficacy data remains limited. This research to investigated the effect of mecobalamin supplementation on the severity of Painful Diabetic Neuropathy in type 2 diabetes mellitus patients. This research is a non-randomized clinical trial, 16 patients were given 500 ?g of intramuscular Mecobalamin 8 times over 30 days (n=8) and 5 times over 10 days (n=8). Subjects underwent measurements VAS, TSS, BDNC and ENMG before and after intervention. VAS (p-value=0,022), TSS (p-value=0,020) and BDC (p-value=0,003) was significant improved in 8 times administration group. VAS (p-value=0,045) dan BDC (p-value=0,014) was significant improved in 5 times administration group, where TSS improved but not significant. The 8 times administration group was better compared to the 5 times administration group in improvement of VAS (p-value=0,016). Based on this research, The addition of mecobalamin 8 times and over 5 times in the management of Diabetic Neuropathic Pain can be useful in reducing neuropathic pain
Substitusion of Mackerel (Rastrelliger sp) on Nugget Products as Emergency Food
No full textIn emergencies, ensuring proper nutrition for toddlers is crucial, including the availability of specialized food products such as mackerel-based nuggets. This study aim to evaluate the impact of mackerel substitution on organoleptic characteristics, proximate composition, fatty acid profile, and Vitamin D content in nuggets as emergency food. The research employed an experimental approach using a completely randomized design (CRD) with three treatment groups and one control: F0 (0%), F1 (40%), F2 (50%), and F3 (60%). Organoleptic data were analyzed using the Kruskal-Wallis, and the Mann-Whitney test to determine statistical significance. Meanwhile, proximate composition (protein, fat, carbohydrates, moisture content, and ash content), fatty acid profile, and vitamin D levels were examined using an independent t-test. Findings from the hedonic test revealed that F3 (60%) was the most preferred formula. This formula exhibited a slightly brownish color, a strong aroma, a somewhat soft texture, and an intense flavor. Proximate analysis showed that F3 contained 16,18 g of carbohydrates, 2,88 g of fat, 21,65 g of protein, 2,24 g of ash, and 57,05 g of moisture. Additionally, its fatty acid composition included 0,0864% DHA, 0,0079% EPA, 0,1005% omega-3 fatty acids, 0,3083% omega-6 fatty acids, 1,255% omega-9 fatty acids, and 0,0096% linolenic acid. The vitamin D content in this formula was recorded at 1,13 mcg. The study results indicated significant differences between the control and the selected formula in terms of proximate composition, fatty acid profile, and Vitamin D levels. Therefore, incorporating mackerel into nugget production can enhance the product's organoleptic characteristic
Aktivitas Kelompok: Menggambar terhadap Halusinasi Dengar pada Pasien Skizofrenia
No full textMental disorders occur due to disturbances in the thought process, emotions, and behavior, which cause maladaptive responses. Schizophrenia is one of the most common mental disorders, characterized by impaired cognitive function. One of the symptoms that often appears in schizophrenia is sensory perception disorders, especially auditory hallucinations. The purpose of this study was to determine the difference in the scale of auditory hallucinations before and after being given Group Activity Therapy (TAK) drawing intervention. The results of observations in the Nakula Room of Dr. Arif Zainudin Mental Hospital showed that the majority of patients experienced auditory hallucinations. This study used a quasi-experimental design with a one-group pretest-posttest approach. The sampling technique used was total non-probability sampling, involving 6 patients who experienced sensory perception disorders: auditory hallucinations. The instrument used in this study was the Auditory Hallucination Rating Scale (AHRS) questionnaire. Data analysis was carried out using the Wilcoxon Signed-Rank test, which showed a significance value of 0,027 (p-value <0,05). This indicates a significant difference in the scale of auditory hallucinations before and after being given group activity therapy drawing. Group drawing activity therapy has a significant effect on the ability to control auditory hallucinations in schizophrenia patients
Determinant of Pulmonary Tuberculosis in Outpatients at Daya Hospital, Makassar City
No full textIndonesia ranks third with the highest number of TB patients in the world after India and China. Initial data collection conducted at Daya Kota Makassar Regional General Hospital revealed that Pulmonary Tuberculosis is among the top 10 diseases in both outpatient and inpatient cases. The incidence of Pulmonary TB in outpatient cases was 783 in 2019, 210 in 2020, and 238 in 2021. The objective of this research is to determine the determinants of pulmonary tuberculosis incidence in outpatient patients at Daya Kota Makassar Regional General Hospital. The research method employed is quantitative research with a cross-sectional design. The population for the study includes all outpatient patients in the Pulmonary Clinic of Daya Kota Makassar Regional General Hospital, totaling 142 individuals, with a subject of 49 subjekts selected using purposive sampling technique. Bivariate analysis uses Chi-square, and multivariate analysis employs logistic regression. The research results indicate a correlation between knowledge (p-value=0,004), smoking behavior (p-value=0,003), and nutritional status (p-value=0,019) with the incidence of Pulmonary Tuberculosis. However, there is no socio-economic relationship with Pulmonary Tuberculosis incidence (p-value=0,169) at Daya Kota Makassar Regional General Hospital. It is recommended that the community participate in the socialization activities for preventing the risk of Pulmonary Tuberculosis provided by health cadres to reduce the incidence of Pulmonary Tuberculosis
Efektivitas Edukasi Anemia terhadap Tingkat Pengetahuan Siswi
No full textPermasalahan anemia di kalangan muda (remaja) di Indonesia masih menjadi masalah kesehatan masyarakat yang serius, karena prevalensi kasusnya mencapai 21,7% yang disebabkan karena kurangnya pengetahuan. Kegiatan edukasi ini bertujuan untuk meningkatkan pengetahuan remaja tentang anemia dan menganalisis tingkat pengetahuan remaja dengan menggunakan kuesioner pengetahuan. Kegiatan ini diikuti oleh 35 peserta remaja putri SMA Negeri 9 Depok. Peserta edukasi diberikan lembar kuesioner sebelum diberikan edukasi (pretest) dan lembar kuesioner setelah diberikan edukasi (posttest) untuk mengetahui sejauh mana perubahan tingkat pengetahuan peserta tentang anemia. Berdasarkan hasil pretest dan posttest yang telah dilakukan, diperoleh rata-rata skor pretest adalah 80,00, sedang rata-rata posttest 95,71. Hal ini membuktikan bahwa peningkatan skor pengetahuan secara statistik bermakna signifikan. Melalui kegiatan edukasi ini, diharapkan para remaja dapat meningkatkan pengetahuannya mengenai anemia
Psychometric Test of Shoulder Pain and Disability Index (SPADI) Indonesian Version in Frozen Shoulder Et Causa Capsulitis Adhesive
No full textFrozen shoulder is a common condition tha causes pain and resulting limitation of movement affecting 2-5% of the general population. It is more common in women than men, generally aged 40-70 years, so a valid and consistent instrument is needed to see pain and disability in shoulder pathology with the Shoulder Pain and Disability Index (SPADI) instrument. The purpose of the study was to determine the validity and reliability of the Shoulder Pain and Disability Index (SPADI) questionnaire in the Indonesian version. This research was a quantitative study with a methodological approach. The research was conducted in September 2023 in two places, namely Kustati Hospital and UNS Hospital, with a total sample of 41 subjects using the purposive sampling technique. The SPADI instrument was given twice with a distance of 2 weeks, getting very good test-retest reliability results (ICC 0,986; p-value <0,001; and 95% CI 0,975–0,993). Internal consistency is good, with a Cronbach's alpha value of 0,935. The results of the content validity test was based on the corrected item total correlation value above 0,3. The conclusion of this study is that the Indonesian version of the SPADI instrument is declared reliable and valid for use in patients with frozen shoulder e.c adhesive capsulitis to asses the level of pain ad disability in shoulder
Fatty Acid Composition and Effect of Repeated Use on the Quality of Traditional Mandar Cooking Oil
No full textTraditional coconut oil of mandar is oil extracted from coconut flesh through a heating process. Repeated use of cooking oil has the potential to reduce the oil’s quality, characterized by an increase in free fatty acid levels. The study aimed to analyze the fatty acid composition and the effect of repeated use on the quality of traditional coconut oil from mandar. This study was an experimental design with a completely randomized design (CRD). The frying technique used was deep fat frying with a total of 9 liters of oil. The product being fried was kepok banana, with a total weight of 9 kg, fried at 180°C for 10 minutes in each cycle. There was a 5-minute interval between frying cycles, and a total of 9 cycles were performed on the same day. The parameters analyzed in this research were free fatty acid content and fatty acid profile of traditional coconut oil of Mandar. The results showed that the fatty acid profile was dominated by saturated fatty acids (76,49%) and a small portion of unsaturated fatty acids (0,59%). The level of ALB in traditional coconut oil of mandar did not exhibit significant differences (p>0,05) from the initial use up to the 9th repetition. Thus, traditional coconut oil from Mandar remains suitable for frying purposes for up to 9 cycles