1,846 research outputs found
Inflammation in cardiac disease: towards improving diagnosis and new therapies
No full textNiessen, J.W.M. [Promotor]Rossum, A.C. van [Promotor]Krijnen, P.A.J. [Copromotor]Juffermans, L.J.M. [Copromotor
De waterbeweging in kanalen veroorzaakt door scheepvaart
No full textCollegedictaat in aansluiting van het vak Scheepvaartwegen.Hydraulic EngineeringCivil Engineering and Geoscience
Over versnippering van sociaal-wetenschappelijk onderzoek in Nederland
No full textA report on the study "Differentiatie in sociaal- en geesteswetenschappelijk onderzoek: een studie naar het denken over en het beleid ten aanzien van \u27versnippering\u27, met bijzondere aandacht voor de demografie, de taalwetenschap en de sociale en economische geschiedenis" ([Differentiation in Social Science and Humanities Research: A Study on the Thought on and Policy of \u27Fragmentation\u27, with Special Attention Given to Demography, Linguistics, and Social and Economic History], The Hague: Netherlands State Publishing House, 1984). The study presents an approach for distinguishing & evaluating phenomena of differentiation in the social sciences & the humanities. Criticisms are made about the use of the "care of knowledge" concept as a tool for distinguishing between functional & dysfunctional differentiation. In Verschillende visies op versnippering?: Repliek op J. A. van Rossums \u27Over versnippering van sociaalwetenschappelijk onderzoek in Nederland\u27 (Different Visions of Fragmentation?: A Reply to J. A. van Rossum\u27s \u27On Fragmentation of Social Science Research in the Netherlands\u27), F. L. Leeuw & A. van Gageldonk offer a more positive evaluation of the original report. 4 References. Modified H
Preventive rehabilitation in patients treated with chemoradiation for advanced head and neck cancer
No full textLisette van der Molen onderzocht twee preventieve slik- en kauwrevalidatiemethoden. Ze deed dit bij patiënten met een kwaadaardige tumor in het hoofd-halsgebied die worden behandeld met chemotherapie en bestraling. Een intensief programma van slik- en kauwspieroefeningen is goed uitvoerbaar en de therapietrouw blijft hoog. Deze preventieve revalidatie lijkt de slik- en kaakproblemen te beperken en vermindert stem- en spraakproblemen. De methode is opgenomen in het nieuwe hoofd-halsrevalidatieprogramma dat de promovendus in het NKI-AVL ontwikkelde
Final Report of the DAUFIN project
No full textDAUFIN = Data Assimulation within Unifying Framework for Improved river basiN modeling (EC 5th framework Project
Impact of synaptic depression on network activity and implications for neural coding
No full textShort-term synaptic depression is the phenomena where repeated stimulation leads
to a decreased transmission efficacy. In this thesis, the impact of synaptic depression
on the responses and dynamics of network models of visual processing is investigated,
and the coding implications are examined. I find that synaptic depression can fundamentally change the operation of previously well - understood networks, and explain
temporal nonlinearities present in neural responses to multiple stimuli. Furthermore,
I show, more generally, how nonlinear interactions can be beneficial with respect to
neural coding.
I begin chapter 1 with a short introduction. In chapter 2 of this thesis, the behaviour
of a ring attractor network is examined when its recurrent connections are subject to
short term synaptic depression. I find that, in the presence of a uniform background
current, the activity of the network settles to one of three states: a stationary attractor
state, a uniform state or a rotating attractor state. I show that the rotation speed can be
adjusted over a large range by changing the background current, opening the possibility to use the network as a variable frequency oscillator or pattern generator, and use
mathematical analysis to determine an approximate maximum rotation speed. Using
simulations, I then extend the network into two - dimensions, and find a rich range of
possible behaviours.
Processing in the visual cortex can be non - linear: the response to two objects or other
visual stimuli presented simultaneously is often less than the sum of the responses
to the individual objects. A maximum function has in some cases been proposed to
describe these competitive interactions. More recent data has emphasised that such
interactions have temporal aspects as well, namely that the response to an initially
presented stimulus can suppress the response to a stimulus presented subsequently, especially if the first stimulus is presented at high contrast. Chapter 3 of this thesis will
present a simple neuronal network featuring synaptic depression which can account for
much of the temporal aspects of this behaviour, whilst remaining consistent with older
data and models. Furthermore, it will show how this model leads to several strong predictions regarding the processing of low contrast stimuli sequences, as well suggesting
a link between response latency and suppression strength. The response of the model
to a structured sequence of input stimuli also appears to anticipate future stimuli, and
we predict that the magnitude of this stimulus anticipation will decrease as contrast is
decreased.
Following on from investigating the temporal aspects of responses to stimuli pairs, in chapter 4 this thesis examines an abstract model of how coding is impacted by non -
linear interactions, for both structured and unstructured stimuli spaces. I find that non-
linear methods of responding to pairs of stimuli presented simultaneously can have a
beneficial effect on coding capacity, with linearly combined responses generally leading to the highest decoding errors rates. This thesis goes on to examine the interplay
between this models noise assumptions and the decoding performance, and finds that
many of the assumptions made can be weakened without changing, qualitatively, these
findings.
In chapter 5, this thesis examines layered networks of noisy spiking neurons with recurrent connectivity and featuring depressing synapses. The contrast dependent latency
and spike count statistics of the model are analysed and are found to be strongly dependent on the parameters of the noise. The tuning of parameters for models containing
noisy IF neurons is discussed, and an information theoretic approach to tuning is outlined which successfully reproduces earlier work in which noise was tuned to linearise
the response of a spiking network. The approach is applied to maximise the ability
of the network to filter rapid noise transients at low contrast. I finish the thesis with a
short concluding chapter
DINSP 05.261
No full textOp het terrein tussen de Boschweg en de Oranjestraat te Rossum zijn in 2005 en 2006 door BAAC bv verschillende archeologische onderzoeken uitgevoerd: opgraving Kulturhus, archeologische begeleiding RSC/Oranjestraat (DINSP), inventariserend veldonderzoek door middel van proefsleuven (IVO) en Definitief archeologisch onderzoek (DO) Oranjestraat 2 (DINOS) en IVO sportveld-Oranjestraat (DINOT).
Deze drie onderzoeken hebben individuele datasets opgeleverd en zijn apart gearchiveerd. Deze dataset betreft deelproject DINSP.
Het meest noordelijk deel van het onderzoeksgebied was verstoord tot op 165 cm – mv. Ten zuiden hiervan was de grond ook verstoord maar met een beperkte diepte. Onder de verstoring bevond zich hier zelfs nog een grotendeels intacte bodemopbouw. Het grootste deel van het terrein was nog intact. Onder het esdek zijn dan ook enkele sporen aangetroffen die wijzen op archeologische waarden in de ondergrond. Mogelijk maken deze sporen, waaronder een waterkuil, deel uit van een nederzetting. De datering van de waterkuil ligt, op basis van het gevonden aardewerk, vermoedelijk in de bronstijd/ijzertijd. Of de overige sporen ook uit diezelfde periode dateren is niet duidelijk, maar wel aannemelijk.
Vanwege de geringe breedte van de sleuven kon de exacte aard en gaafheid van de sporen niet goed bepaald worden
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