161 research outputs found
PROPOSE AND IMPLEMENTATION OF MISSILE APPRECIATION BY USING INTERNET OF THINGS
No full textIn the modern situation we're going thru lots of dangers through the use of means of bomb blasts so our task is to prepare an unmanned robotic that allows you to catch the bomb it's misting likely to not positive find the bomb nonetheless additionally reveals feature of bomb with the help of using means of the use of general practitioners component as well as the location of bomb can be intimated to the special personality thru web. We are interfacing the online electronic cam to control the robotic. Below we are using a steel detector to find the bomb as a result of the reality we understand that any type of bomb consists of a couple of passion or percent of steel components. We create correct right here to present a maker that does away with the desire for people in the minefield with the valuable source of altering them with a from another location handled discovery car. This cars and truck could be linked wirelessly to a base terminal situated at a relaxing range from the threat area. Doing so, this tool will certainly aid in conserving lives, reducing costs as well as embellish efficiency in the mine discovery technique. The steel detector circuit is interfaced with the robot and also it is left at the favoured are looking for an area to ensure that it will certainly stumble upon the steel parts made use of within the landmines. One of the most vital benefits of this endeavour is that we have the ability to making this robot at a reduced cost as well as extra unskilled
Assessment of WRF planetary boundary layer schemes in the simulation of fog events over Hungary
No full textAccurate depiction of meteorological conditions, especially within the planetary boundary layer (PBL), is essential for fog forecasting. This study examines the sensitivity of the performance of the Weather Research and Forecast (WRF) model to the use of four different PBL schemes [Yonsei University (YSU), asymmetric convective model version 2 (ACM2), quasinormal scale elimination (QNSE), and Mellor-Yamada-Nakanishi-Niino version 3.0 (MYNN3)]. For this case study we have taken the fog event occurred in November 23-24, 2020. Surface observed temperature and relative humidity, furthermore, sounding data are compared with the output of the 36 hours, high-resolution weather forecast. The horizontal extension of the simulated fog is compared with satellite observations. The visibility is calculated from the prognostic variables of drop number concentration and mixing ratio. The simulated visibility and fog duration are validated by the visibility and fog duration evaluated by ceilometer observations. Validation of thermodynamical values such as 2-m temperature and relative humidity reveals, that during most of the simulation time, the bias is significant between the simulated and observed data. Results show that the PBL parameterization scheme significantly impacts fog microphysics also. The QNSE scheme results in unrealistic early formation of the fog, and too large liquid water content. YSU and ACM2 simulated the duration of fog to be rather short comparing with the other two PBL schemes. The best fitting with observed data is found in the case of MYNN3 PBL schemes
Design And Implementation Of High Security Banking System By Using Iot Technology
No full textThis project focuses on designing and also creating biometric finger print modern technology based loan deal system for buying. As even more worldwide financial activity comes to be digitally-based, financial institutions are utilizing brand-new technologies to create next-generation identification controls to deal with fraud, make purchases much safer, and also boost the client experience. The sensing unit is a solid-state finger print sensing unit that dependably catches fingerprint info. It is created to integrate right into devices for enhanced safety as well as convenience. The sensing unit supplies a dependable, fast and also easy to use option to passwords, PIN's and other forms of individual verification. Individual need not lug any kind of physical cards (credit score, debit and so on) or cell phones for money transaction. Individual simply need to keep finger print go into purchase amount using keypad. This purchase details is sent to server over safe IoT (WiFi) and more processing done there. If the deal achieves success then individual obtains SMS confirmation message to his registered telephone number. This onboard computer includes number of input as well as outcome ports. The onboard computer system is generally termed as micro controller. The input and also output port of the micro controller are interfaced with various input and output modules depending on the demands. In other words micro controller works as a communication medium for all the components involved in the job. The tool likewise includes GSM modem, Wi-fi components, Keypad, LCD which presents the information regarding purchases
Knowledge Management and its Utilisation : an Overview
No full textThe paper covers different aspects of Knowledge Management(KM) and its
applications. Stress is given to the relevance of KM for organizations. The paper considers KM as a cross-disciplinary domain. The importance of Librarians & Information professionals in KM of organizations is pointed out. Also discusses Knowledge creation and knowledge sharing, the challenges for KM, and different types of knowledge management. Examples of initiatives are also provided
Innovative Motor Vehicle Passing Alert Scheme By Using Internet Of Things
No full textOver the past few years, several attempts have been made to integrate the Internet of Things (IoT) with smart city environments. The reason why the city needs to become 'smart' is a possible way to reduce problems due to the city's population growth and rapid urbanization. Attention has also been paid to pedestrian crossings, as it can be one of the most dangerous places in the place of handover. Information and communication technologies can be practically a remarkable tool in the growing infrastructure that can manage first-class pedestrian crossings. This mission uses a laptop on board, usually called a microcontroller. This is the heart of the mission. This on-board computer can talk to the sensors used correctly. The console has some internal reminders to preserve the code. This memory is used to empty meeting units in the console. And the operation of the controller depends on the assembly instructions. When the vehicle arrives, the microcontroller sounds indicators and clears the moving platform. Microcontroller markers help assess platform movement. The device detects any presence of people and controls tools such as lighting fixtures. The device uses the LDR sensor to detect day and night light and controls electrical devices such as lighting, fans and many more using the relay switches
Design and Implementation of Face Reorganization Based Smart Home Automation and Security System
No full textIn reality, security is one of the significant issues. As technology is getting progressed numerous security issues are emerging. The existed created security techniques have a few blemishes and they can be hacked. The proposed framework for settling the security issue depends on face location and acknowledgment utilizing Raspberry pi camera. The substance of an individual is caught by the camera and contrasted and the procured data set. On account of obscure/unapproved access, the face picture of the individual will be caught and advised to the concerned specialists through SMS utilizing GSM module and alert will be produced on account of unapproved access. This venture delivered precise outcomes in the two cases: approved and unapproved access. The presented framework gives a minimal effort answer for checking and controlling the houses, various associations like banks, colleges
Поліморфізм CYP2C19 в результаті лікування есциталопрамом у популяції Південної Індії з важким депресивним розладом
No full textVarious CYP2C19-mediated metabolizer groups may arise as a result of inter-individual variability, which potentially influences the efficacy and safety of escitalopram. Hence, it is crucial to establish a comprehensive collection of information relevant to each phenotype regarding the efficacy and tolerability of therapy. This will enable psychiatrists to make optimal decisions for individual patients.
The aim of the study: The aim of this study is to classify MDD patients into various CYP2C19 metabolizer groups and to determine the association between phenotype and treatment outcome.
Materials and Methods: The study enrolled 119 escitalopram monotherapy-treated MDD patients aged 18–58. MADRS, HDRS-17, and CGI were used to measure efficacy at baseline, weeks 4, 8, and 12. Safety and tolerability outcomes were examined from occurring ADRs. Clinical outcomes were compared among phenotypes based on changes in HDRS-17 and CGI scores from week 4 to week 12.
Results: Subjects were categorized by CYP2C19 genotype: 20 poor (PM), 64 intermediate (IM), 24 extensive (EM), and 11 ultra-rapid (UM) metabolizers. Response and remission occurred in 67.2 % and 26.8 % of the 119 subjects at the end of the 12th week of the study. The response rate in PM was much lower (21.6 %) compared to EM. There were 312 adverse drug reactions (ADRs), and 88 (73.94 %) individuals had at least one. In safety data, nervousness was the most common ADR among the four groups 66 (55.4 %), followed by decreased appetite 48 (40.3 %). There were no severe ADRs. Men had more ADRs than women.
Conclusion: CYP2C19 genotyping may help personalize escitalopram medication. The study found that the reduced ability of PM to metabolize escitalopram is probably associated with the decreased efficacy and tolerance shown in PM compared to EM and IM. The relationship between metabolizer status and treatment response followed the anticipated direction. Our findings should guide future clinical studies that include pharmacokinetic assessmentsРізні групи метаболітів, опосередкованих CYP2C19, можуть виникнути внаслідок міжіндивідуальної мінливості, що потенційно впливає на ефективність і безпеку есциталопраму. Отже, надзвичайно важливо створити повний збір інформації, що стосується кожного фенотипу щодо ефективності та переносимості терапії. Це дозволить психіатрам приймати оптимальні рішення для окремих пацієнтів.
Мета дослідження: Метою цього дослідження є класифікація пацієнтів з ВДР на різні групи метаболізаторів CYP2C19 і визначення зв’язку між фенотипом і результатом лікування.
Матеріали та методи: У дослідженні взяли участь 119 пацієнтів із ВДР, які отримували монотерапію есциталопрамом, віком 18–58 років. MADRS, HDRS-17 і CGI використовувалися для вимірювання ефективності на початковому етапі, після 4, 8 і 12 тижнів. Результати щодо безпеки та переносимості досліджувалися на основі побічних реакцій. Клінічні результати порівнювали за фенотипом на основі змін у HDRS-17 та оцінках CGI з 4 по 12 тиждень.
Результати: Суб’єкти були класифіковані за генотипом CYP2C19: 20 із низьким (PM), 64 з проміжним (IM), 24 з інтенсивним (EM) та 11 із надшвидким (UM) метаболітами. Відповідь і ремісія відбулися у 67,2 % і 26,8 % із 119 пацієнтів наприкінці 12-го тижня дослідження. Рівень відповідей у PM був значно нижчим (21,6 %) порівняно з EM. Було зареєстровано 312 побічних реакцій (ПР), і 88 (73,94 %) осіб мали принаймні одну. У даних про безпеку нервозність була найпоширенішою побічної реакцією серед чотирьох груп у 66 осіб (55,4 %), наступним за поширеністю було зниження апетиту у 48 суб’єктів (40,3 %). Серйозних побічних реакцій не було. Чоловіки мали більше побічних реакцій, ніж жінки.
Висновки: Генотипування CYP2C19 може допомогти персоналізувати препарат есциталопрам. Дослідження показало, що знижена здатність ПМ метаболізувати есциталопрам, ймовірно, пов’язана зі зниженою ефективністю та толерантністю, виявленими при ПМ, порівняно з ЕМ та ІМ. Зв’язок між статусом метаболіста та відповіддю на лікування слідував очікуваному напрямку. Наші висновки повинні ґрунтуватися на майбутніх клінічних дослідженнях, які включають оцінку фармакокінетик
Effectiveness of Pilates Exercise and Conventional Exercise on Trunk and Postural Stability in Collegiate Basketball Players
No full textIntroduction: To study the effects of Pilates exercise and conventional exercise on trunk and postural stability in collegiate basketball players.
Objectives: To determine the effects of pilates exercise on trunk and postural stability in collegiate basketball players. To determine the effects of conventional exercise on trunk and postural stability in collegiate basketball players.
Methods: This is a quasi-experimental design of pre and post-test type. The study duration was for 6 weeks, age between 18-25 years and the study conducted on university players. The modified star excursion balance test and double leg lowering test was used as the outcome measures to evaluate the postural control and core muscle strength. Subjects were explained about the training protocols.
Procedure: Subjects in Group-A underwent Pilates exercise and Group-B underwent conventional exercise. The data was collected prior to the training program as well at the end of the training program. A combination of mobility and stability is required by active people for optimal functional performance and for the correction of poor posture, muscle imbalances and poor biomechanics. The concept of trunk mobility and stability contributing to improved performance was used in training and rehabilitating athletes today.
Conclusions: The Pilates exercise shows better improvement than the conventional exercise in trunk and postural stability. So, it is concluded that Pilates exercise training is recommended to improve trunk and postural stability of collegiate basketball players
Severity of primary open-angle glaucoma in patients with hypertension and diabetes
No full textAnadi Khatri,1 Jeevan Kumar Shrestha,2 Madhu Thapa,2 Bal Kumar Khatri,3 Muna Kharel3 1Department of Ophthalmology, Vitreo-Retina Fellow, Lumbini Eye Institute, Siddharthanagar, Nepal, 2Department of Ophthalmology, B. P. Koirala Lions Centre for Ophthalmic Studies, Institute of Medicine, Tribhuvan University Maharajgunj, Kathmandu, Nepal, 3Birat Eye Hospital, Biratnagar, Nepal Background: Primary open-angle glaucoma (POAG) is a progressive optic neuropathy with numerous risk factors. Its severity with associated risk factors remains a widely debated topic. Aim: To evaluate the severity of POAG in patients with hypertension (HTN) and diabetes or both. Patients and methods: This hospital-based, cross-sectional descriptive study was conducted for a period of 18 months from January 2016 to June 2017. Diagnosed cases of POAG were evaluated for severity with associated risk factors. Results: A total of 221 patients were enrolled in the study. The mean age of the patients was 54.4 (SD ± 15.9) years with a male to female ratio of 0.93:1. Of the 221 patients, 68 (31%) had a family history of POAG. Mean intraocular pressure was 15.8±4.87 mmHg, and mean central corneal thickness was 535.4±34.9 μm. A total of 81 (36%) patients had HTN, 21 (9.50%) had diabetes mellitus (DM), and 15 (6.80%) had both HTN and DM. Analysis using SPSS version 20 was done. The severity of POAG was found to be significantly higher in patients with HTN, DM, or both when evaluated on the basis of anatomical and functional loss. Conclusion: POAG patients with HTN, DM, or both were found to have more severe POAG. Patients with these risk factors could represent “high-risk patients” with POAG. Patients with HTN and DM, or both may require evaluations on a more frequent basis to access the progression/severity of POAG. Keywords: glaucoma in Nepal, POAG in Nepal, severity of POAG, hypertension, diabetes, systemic disorders in POA
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