3,532 research outputs found
Extended and saturation prostatic biopsy in the diagnosis and characterisation of prostate cancer: A critical analysis of the literature
No full textObjective: To review and critically analyse all the recent literature on the detection and characterisation of prostate cancer by means of extended and saturation protocols. Methods: A systematic review of the literature was performed by searching MedLine from January 1995 to April 2007. Electronic searches were limited to the English language, and the key words "prostate cancer," "diagnosis,". "transrectal ultrasound (TRUS)," "prostate biopsy," and "prognosis" were used. Results: The prostate biopsy technique has changed significantly since the original Hodge sextant biopsy protocol. Several types of local anaesthesia are now available, but periprostatic nerve block (PPNB) has proved to be the most effective method to reduce pain during TRUS biopsy. It remains controversial whether PPNB should be associated with other medications. The optimal extended protocol (sextant template with at least four additional cores) should include six standard sextant biopsies, with additional biopsies (up to 12 cores) taken more laterally (anterior horn) to the base and medially to the apex. Repeat biopsies should be based on saturation biopsies (number of cores >= 20) and should include the transition zone, especially in a patient with an initial negative biopsy. As a means of increasing accuracy of prostatic biopsy and reducing unnecessary prostate biopsy, colour and power Doppler imaging, with or without contrast enhancement, and elastography now can be successfully adopted, but their routine use is still controversial. Conclusion: Extended and saturation biopsy schemes should be performed at first and repeat biopsy, respectively. The widespread use of local anaesthesia makes the procedures more comfortable. (c) 2007 European Association of Urology. Published by Elsevier B.V. All rights reserved
La filosofía del derecho de Alexandre Kojève
No full textThis article is a presentation of Alexandre Kojève’s philosophy of law, exposed in his Esquisse d’une phénoménologie du droit (1981). Little attention has been paid to this work. So there is a gap that has to be filled with a critical reflection of its strengths. Among them, undoubtedly, we count the fact that Kojève is introducing a conception of international justice that casts a singular light on current debates about cosmopolitanism and globalization. According to this author, citizenship is the key element of the process of global expansion of the juridical sphere. In sum, Kojève’s philosophy is useful to reflect upon the contrast between the juridical and the political, which is the basis for all philosophy of law, in order to achieve world peace and international justice.Este artículo es una presentación de la filosofía del derecho de Alexandre Kojève contenida en su Esquisse d’une phénoménologie du droit (1981). La poca atención que dicha obra ha recibido es un vacío que debiera llenarse con una reflexión crítica de sus puntos fuertes. Entre ellos destaca una concepción de la justicia internacional que proyecta una luz muy singular sobre los actuales debates en torno a la globalización y el cosmopolitismo. A ojos de este autor, la ciudadanía es el elemento clave para aquilatar la expansión global de lo jurídico. En suma, Kojève aparece como un valioso referente en la labor de pensar la contraposición entre lo jurídico y lo político que está en la base de toda filosofía del derecho, con la aspiración al logro de la justicia internacional y la paz mundial en el horizonte
Reconfiguração do consensualismo contratual: as ações tituladas nominativas e os limites à transmissão
No full textPartimos da evolução histórica do consensualismo contratual salientando os
principais carateres que, nos diversos momentos históricos, se foram evidenciando.
Numa segunda etapa exploramos os fundamentos dogmáticos do modelo de
transmissão contratual assumido pelo legislador e a sua viabilidade no sistema
jurídico global, em particular, no direito dos valores mobiliários. Constatamos a
crescente necessidade na prática mercantil e inevitabilidade no sistema jurídico
global da admissibilidade da existência de contratos de compra e venda de natureza
meramente obrigacional. Num terceiro momento desenvolvemos os principais
aspetos do regime jurídico aplicável às ações tituladas nominativas fora do mercado
regulado, em particular, os principais limites à transmissão, enquanto instrumentos/barreiras ao consensualismo contratual.We start from the historical evolution of contractual consensualism emphasizing the
main aspects that, in different historical moments, were showing up. In a second
stage we explore the dogmatic foundations of the transmission model contractual
assumed by the legislator and its viability in the global legal system, in particular, in
securities law. We note the growing need in commercial practice and inevitability in
the global legal system the admissibility of the existence of contracts of sale purely
obligatory. In the third stage we develop the main aspects of the legal regime
applicable to nominative titled actions outside the regulated market, in particular,
the main limits to the transmission, as instruments / barriers to contractual
consensualism
“Era por Alexandre tod’esto demostrado”: ¿pruebas verídicas y pruebas engañosas en el Libro de Alexandre?
No full textEl Libro de Alexandre es un texto de s. XIII, que se escribió en la España medieval. En este escrito, el autor pretende demostrar que, en el Alexandre, algunas de las situaciones que se ponen a prueba son aceptadas, pero eso no significa que el macedonio gane la prueba. El articulo esta dividido en tres apartados. En el primero, el autor da cuenta de la historia textual de la obra y también dedica ciertas líneas al Estado de la cuestión del texto; mientras que, en la segunda parte, nos guía a conceptos etimológicos de los términos prueba, evidencia y demás. En el tercer apartado se centra en algunas pruebas expuestas en el Libro de Alexandre.The Libro de Alexandre is a literary work, written during the medieval Spain. In this paper, the author tries to demonstrate that, carefully reading the L.A, some of the situations that are set as proves are accepted, but it does not mean that Alexander can be a victor. This paper is divided in three sections: firstly, the author tells the textual history of the L.A and, then, tries to update the State of art: on the other hand, in the second part, the author offers meanings about terms as: prueba and evidencia. Finally, the author focuses on certain passages contained in the Libro de Alexandre that can be taken as failed proves
Mixing the Immiscible: Improvisation within Fixed-Media Composition
No full textThis paper will explore ways in which mastered improvisation practice, with the studio as an instrument, is a proposed avenue to bridge the historical dichotomy between what Ted Gioia describe as ‘the aesthetics of perfection’ and ‘the aesthetics of imperfection’. It is proposed as a way to re-embody fixed music, as experimented by the author through the composition of his last fixed-media work. This will be put in the context of a wider trend observed amongst the current emerging generation of composers interested in the aesthesics of the work, by opposition to the previous generations that placed the value of the work in its poietics. The vital and primal importance of practice outcome as practice-based research’s main document will also be advocated for, as these trends are happening in the laboratory of live music
Alexandre de Rhodes (1593?-1660)
No full textBiografia do jesuíta francês Alexandre de Rhodes (1593?-1660), missionário na Cochinchina (Vietname) e no Tonquim. Autor do Dicionário Anamita-Português-Latim (1651), Rhodes foi uma figura central no choque de interesses entre o Padroado Português e as ambições diplomáticas e políticas da França na Indochina e na China.Biography of the French Jesuit Alexandre de Rhodes (1593?-1660), missionary in Cochinchina (Vietnam) and Tonkin. Author of the Anamita-Portuguese-Latin Dictionary (1651), Rhodes was a central figure in the clash of interests between the Portuguese Padroado and France's diplomatic and political ambitions in Indochina and China.info:eu-repo/semantics/publishedVersio
La Clerecía de "Alexandre"
No full textEl artículo reflexiona sobre la educación que recibe Alexandre “El grande” a manos de su profesor Aristóteles, retratado en el “Libro de Alexandre”; a continuación analiza las disciplinas que compusieron dicho programa con el interés de proponer una interpretación de la lista de las siete artes liberales mencionadas. Este artículo ofrece una visión de las diferentes maneras en las que los textos reflejan la “clerecía” del protagonista así como de otros personajes, incluyendo el anónimo autor de los mismos. Cualquiera que se dedique a las mencionadas artes liberales será glorificado y Alexandre se presenta él mismo como modelo ideal de un príncipe en quien la nobleza y al inteligencia van unidas, una defensa clara de la “clerecía” como fuente fundamental de toda excelencia. This article deals with the education imparted on Alexander the Great by Aristotles, as portrayed in the “Libro de Alexandre”, analyzes the disciplines and proposes an interpretation of the list of the seven liberal arts mentioned therein. This article also offers an encompassing view of the different ways in which the text reflects the “clerecía2 of the protagonist as well as that of the other characters, including the anonymous author himself. Anyone who dedicates him or herself to the aforementioned liberal arts is thereby glorified, and Alexander presents himself as the ideal model of a prince in whom nobility and cleverness are joined, in a clear defense of the “clerecía” as the fundamental source of all excellence
The monarchy of Portugal in Alexandre Herculano's work
No full textA pesquisa A Monarquia Portuguesa na Obra de Alexandre Herculano analisa a construção do modelo ideal de monarca por Alexandre Herculano, com especial ênfase na produção histórica em que os monarcas portugueses foram retratados com maior riqueza de detalhes e analisados de forma mais criteriosa. A pesquisa se dá a partir da conjuntura histórica portuguesa marcada pelo estabelecimento do Estado Liberal e pelos debates entre os diferentes grupos políticos em que a participação dos intelectuais é um ponto relevante. No tocante a Alexandre Herculano, o envolvimento do autor em diversas polêmicas e articulações políticas é uma evidência da importância e da atuação da intelligentsia na sociedade portuguesa do século XIX. Ao lado da conjuntura histórica na qual a obra de Herculano foi produzida, o universo conceitual forjado pelo autor com fundamento nos pressupostos teóricos e políticos também foi contemplado, pois o modelo de monarca construído pelo autor foi elaborado a partir deste universo conceitual que, conforme os pressupostos teóricos empregados nesta pesquisa atuam e interferem nos debates contemporâneos à obra.The research The Portuguese Monarchy in Alexandre Herculanos work analyses the building of the monarchs ideal model (by Alexandre Herculano) especially focusing on the historical production on which the Portuguese monarchs were detailedly portrayed and discerningly analysed. Considering the Portuguese historical conjuncture marked not only by the establishment of the Liberal State but also by the debates among the different political groups in which the intellectuals partaking is relevant. Concerning Alexandre Herculano, the authors involvement in several debates and political articulations is an evidence of the intelligentsias outstanding role in the Portuguese society of the nineteenth century. Along with the historical context in which Herculanos work was produced, the conceptual universe created by the author reasoned on theoretical and political assumptions was also considered because the monarchs model built by the author was created from this universe of concepts that, according to the theoretical assumptions used in this research, act and expand their sphere of influence towards the contemporary debates to his work
Transurethral needle ablation of the prostate: Clinical experience in patients in urinary acute retention
No full textObjective. To evaluate the clinical outcome of patients in urinary retention due to benign prostatic enlargement (BPE) treated using transurethral needle ablation (TUNA), an outpatient procedure requiring only local intra-urethral anaesthesia and intravenous sedoanalgesia. Patients and methods. The TUNA technique was used in 38 patients in acute retention due to BPE, 34 of whom were a poor surgical risk. A special cystoscopic catheter device delivered low-level radiofrequency (RF) energy interstitially to a localized area of the prostate, producing necrotic lesions within the prostatic parenchyma. After treatment, all men were evaluated using urinary flow rates, residual urine volume, the International Prostate Symptom Score and quality of lire score at 1, 3 and 6 months. Results. The mean prostate size was 43.1 g (range 18-90). Tolerance of the procedure when using topical anaesthetic and intravenous sedation was excellent. Of the 38 patients treated using TUNA, 30 (79%) resumed voiding within a mean of 8.7 days (range 2-27). After 6 months, the sustained mean peak flow rate was 10.4 ± 3.4 mL/s and the mean residual volume was 76 ± 45 mL. Five of the patients who did not resume voiding after TUNA underwent retropubic prostatectomy and one patient underwent TURP. The mean prostate size in these patients was 55.7 g. Failure to void was associated with the treatment of too few areas of the prostate for its volume. Conclusion. This study demonstrated that TUNA is highly effective in relieving patients in urinary retention due to BPE and seems particularly suitable for treating patients who are at greater risk during surgery.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
- …
