1,277 research outputs found
Ari naiz y ari dut
No full textSignificaciones del verbo "ari" en sus dos conjugaciones con "izan" y "ukan". Sugiere sustituír algunas locuciones incorrectas por "ari"Meanings of the verb "ari " in both its conjugations with "izan" and "ukan". The author suggests using some wrong expressions by "ari
Uma proposta de ensino de literatura a partir da obra do escritor alagoano Ari Denisson
No full textThis research is based on a qualitative investigation, of the action research type, which suggests that literature classes should study the life and work of the author Ari Denisson, a poet and short story writer from Maceió, with the aim of valuing talents from Alagoas and encouraging a taste for reading and literary production. The actions of this project took place in a public school in a first-year high school class in 2024 and focused on the poetic work “baroque.doc” and the narrative work “Contos Periféricos”. A six-hour teaching sequence culminated in the author's visit to the school and a round of questions from the students. The interview was preceded by analyses of the selected texts and a presentation of the author's biography. The expected result is a way of rescuing the culture of Alagoas and Maceió and a greater appreciation of literature in Portuguese language classes. The authors who are references for this research range from Cosson, Boal, Freire, Rojo, to Antunes, among others.A presente pesquisa baseia-se em uma investigação de cunho qualitativo, do tipo pesquisa-ação que sugere para as aulas de literatura o estudo da vida e obra do autor Ari Denisson, poeta e contista maceioense, no intuito de valorizar os talentos alagoanos e incentivar o gosto pela leitura e produção literária. As ações desse projeto se deram em uma escola pública numa turma do primeiro ano do ensino médio no ano de 2024 e focaram na obra poética “baroque.doc” e na obra narrativa “Contos Periféricos”. Uma sequência didática de seis horas-aula teve como culminância a visita do autor na escola e uma rodada de perguntas dos alunos. A entrevista foi precedida por análises dos textos selecionados e apresentação da biografia do autor. Espera-se como resultado uma forma de resgate da cultura alagoana e maceioense e uma maior valorização da literatura dentro das aulas de língua portuguesa. Os autores que são referências para esta pesquisa vão desde Cosson, Boal, passando por Freire, Rojo, até Antunes, dentre outros
The Afterlife of Ari Nohem
No full textThis chapter traces the circulation of Ari Nohem in manuscript, from its composition through its first appearance in print. The different stages in the reception of Ari Nohem in manuscript offer an alternative history of Kabbalah in the seventeenth and eighteenth centuries, one that has largely been told through the histories of Sabbatianism and Hasidism. The manuscript transmission of Ari Nohem was typical rather than aberrant for texts written by early modern Jewish intellectuals on a variety of subjects: polemical writings on Christianity, esoteric kabbalistic treatises, and epistolary campaigns against the mystical messiah Sabbatai Zevi and his followers. The evidence of these manuscripts, combined with repeated citation of and allusion to Ari Nohem in letters, diaries, treatises, responsa, and compendia composed between 1639 and 1840, indicate that Jews and Christians continued to read Modena's text in nearly every generation between the death of the author and the printing of his book.</p
Review of the safety and efficacy of imiglucerase treatment of Gaucher disease
No full textDeborah Elstein, Ari ZimranGaucher Clinic, Shaare Zedek Medical Center, Jerusalem, IsraelAbstract: Most patients who suffer from symptomatic Gaucher disease will benefit from enzyme replacement therapy (ERT) with imiglucerase. The safety profile is excellent, only a small percentage of those exposed developing antibodies; similarly, very few patients require pre-medication for allergic reactions. Within 3 to 5 years of imiglucerase therapy, best documented at doses of 30 to 60 units/kg/infusion, hepatosplenomegaly can be expected to be reduced so that the liver volume will be maintained at 1 to 1.5 times normal (30% to 40% reduction from advent of ERT) and spleen volume to &le;2 to 8 times normal (50% to 60% reduction from advent of ERT). For anemic and thrombocytopenic patients, with 2 to 5 years of imiglucerase, hemoglobin levels are expected to be &ge;11 g/dL for women and children and &ge;12 g/dL for men; and platelet counts in patients with an intact spleen, depending on the baseline value, should approximately be doubled. Bone crises and bone pain but not irreversible skeletal damage will improve in most patients. Nonetheless, some features and some symptomatic patients apparently do not respond equally well and/or perhaps inadequately. The benefit for patients with the neuronopathic forms is primarily in improved visceral and hematological signs and symptoms. There are still several unresolved issues, the high per-unit cost being an important one, which have spurred the development of biosimilar enzymes as well as chaperone therapies currently in clinical trials.Keywords: Gaucher disease, enzyme replacement therapy, imiglucerase, substrate reduction therapy, pharmacological chaperones, cos
Health consultation, Ari-Zonolite (aka Buster's School of Street Rods facility), Glendale, Maricopa County, Arizona
No full textabstract: This report evaluates the potential exposure pathways associated with vermiculite concentrate processing activities at the Ari-Zonolite facility. The site is located in the near downtown area of Glendale, approximately ½ mile from the city hall, downtown shops, and other buildings. The former Ari-Zonolite facility received vermiculite from the Libby, Montana, mine. From 1951 to 1964, the site was leased the site to the Ari-Zonolite Company. Following the removal of the vermiculite concentrate processing equipment in 1964, several businesses have occupied the site. None of these businesses were involved in vermiculite processing activities. The last occupant of the former vermiculite processing building was an automotive restoration business, which vacated the site in 2002.Under cooperative agreement with the Agency for Toxic Substances and Disease Registry, U.S. Department of Health and Human Services.Includes bibliographical references (p. 17-19)
The X-ray structure of human acid-beta-glucosidase : Implications for second-generation enzyme replacement therapy
No full textTallgrass prairie soil fungal communities are resilient to climate change
No full textClimate models for central United States predict increasing temperatures and greater variability in precipitation. Combined, these shifts in environmental conditions impact many ecosystem properties and services. Long‐term climate change experiments, such as the Rainfall Manipulation Plots (RaMPs), can be used to address soil community responses to simultaneous manipulation of temperature and temporal variability in precipitation. The RaMPs experiment is located in a native tallgrass prairie at the Konza Prairie Biological Station and has been operational since 1998 providing the potential to address responses to long‐term environmental manipulations. To test whether community composition, richness, or diversity respond to environmental change, more than 40,000 fungal amplicons were analyzed from soil samples collected in 2006. The data suggest that soil fungal communities are compositionally resilient to predicted environmental change. This is the case both for the community composition overall as inferred from ordination analyses as well as analyses of variance for each of the most common Operational Taxonomic Units (OTUs). However, while this study suggests compositional resilience, further studies are required to address functional attributes of these communities and their responses to environmental manipulations
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