904 research outputs found

    Report on Underground Solutions for Urban Problems

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    World wide, we see developing nations building new infrastructure as well as developed cities rehabilitating and expanding their infrastructure to meet the demands of increased population, energy efficiency, and environmental awareness of the public. Ten years ago ITA issued its special edition of the Tribune entitled “Why Go Underground, Contribution of the use of Underground space to Sustainable Development.” Working Group N° 20 of the ITA, focused on Urban Problems and Underground Solutions, has continued examining the use of underground space in the urban environment as it evolves with expanding cities and urban densification. This report present examples of the uses of underground space in cities, trends in Metro and roadway planning, and gives an overview of aspects to be considered during the decision making process, in order to optimally include underground solutions.Geoscience & EngineeringCivil Engineering and Geoscience

    Detachable Steerable Clip Applier for Dissection of ITA Branches

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    The internal thoracic artery (ITA) is increasingly being recognized as the best conduit for replacement of diseased coronary arteries. As the ITA is the main blood supply for the sternum, harvesting this artery causes a drop in blood flow, increasing the risk of failing to heal, and risking deep sternal wound infection. Current methods of harvesting the ITA are time consuming, and due to hidden arteries the manoeuvrability of the surgeon is limited. In this project the goal is to develop a new instrument for branch sealing and dissection, that increases the maneuverability, minimizes damage to surrounding tissue while beingmore time efficient. A systematical selection process resulted in the solutions for some of the sub-functions, whereas two subfunctions required more thorough analysis and evaluation. Concept selection for the sub-function Tip-Articulation a more in-depth analysis and experimental evaluation (n=19). The selection of the sub-function Handle-Mechanism is done by analysis of proven concepts, choices are based on the requirements that resulted from consultation with an experienced surgeon from LUMC, literature study, and supervision of experienced medical instrument engineers. A preliminary headroom analysis is done, resulting in an estimated drop of 64.45%for the duration of sealing and dissecting of branches with a relatively bigger diameter. Further research should specifically be aimed on the further development of the chosen concepts

    Book Review -The limitations of Bernard Matolino’s “limited communitarianism”: Continuing the conversations on personhood in African philosophy

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    A review of [Personhood in African Philosophy] 2014. Cluster Publications: Pietermaritzburg. Paperback. Pp 192 Author: Bernard Matolino Discipline: African Philosophy Category: African Philosophy ISBN: 978 1 920620 059 Price: Not stated. Reviewer: Mesembe Ita EDET, PhD Department of Philosophy University of Calabar Calabar – Nigeri

    Smart energy saving at home (ITA dossier no. 10en, July 2014)

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    -> 250 Austrian households were able to gain experience with smart meters in a year-long field trial.-> On average, these households reduced their electricity consumption by around five per cent.-> Smart metering, however, only led to a reduction in energy consumption when combined with comprehensive information and visualization.-> Based on the field trial, recommendations were derived for the design of future programmes on ‘saving energy at home’.Author: Michael Ornetzeder</i

    A função seméica do sufixo -cha e -itu/ita

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    El propósito del artículo es identificar la función sémica del sufijo -cha de la variedad quechua chanka y los sufijos -ita e -itu aglutinados a los lexemas tanto quechuas como hispanos. Para ello, se examina el comportamiento de la partícula -cha en función de la adhesión a bases léxicas de diferentes categorías gramaticales. La autora, a partir de su experiencia como docente y quechuahablante, así como también,  mediante un proceso de inducción interpretativa, elaboró fichas morfológicas con palabras como las siguientes: wasicha "casita", sumaqcha "la bonita",  qipichay "empaquetar", hamunqacha "seguro ha de venir", qamcha "seguro ha de ser tú", de las cuales recogió la muestra de análisis. Como resultado del análisis, se concluye que las funciones sémicas de -cha unidas a bases quechuas y en contacto lingüístico indican conjetura, sustantivación, afecto, acortamiento temporal e ira.The purpose of the article is to identify the sematic function of the suffix -cha of the Quechua variety chanka and the suffixes -ita and -itu attached to both Quechua and Hispanic lexemes. For this purpose, the behavior of the particle is examined as a function of its attachment to lexical bases of different grammatical categories. The author, based on her experience as a teacher and Quechua speaker, as well as through a process of interpretative induction, elaborated morphological cards with words such as the following: wasicha "little house", sumaqcha "the pretty one", qipichay "to pack", hamunqacha "sure to come", qamcha "sure to be you". As a result of the analysis, it is concluded that the semic functions of -cha joined to Quechua bases and in linguistic contact indicate conjecture, substantivation, affection, temporal shortening and anger.O objetivo do artigo é identificar a função semática do sufixo -cha da variedade quechua chanka e os sufixos -ita e -itu anexados tanto aos lexemes quechua como aos hispânicos. Para este fim, o comportamento da partícula é examinado em função de sua fixação a bases léxicas de diferentes categorias gramaticais. A autora, baseada em sua experiência como professora e palestrante quechua, assim como através de um processo de indução interpretativa, elaborou arquivos morfológicos com palavras como: wasicha "casita", sumaqcha "la bonita", qipichay "empaquetar", hamunqacha "seguro ha de venir", qamcha "seguro ha de ser tú". Como resultado da análise, conclui-se que as funções semicinais de -cha anexadas às bases quíchuas e no contato lingüístico indicam conjectura, substantivação, afeto, encurtamento temporal e raiva

    Itaconate reduces proliferation and migration of fibroblast-like synoviocytes and ameliorates arthritis models

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    Fibroblast-like synoviocytes (FLS) play critical roles in rheumatoid arthritis (RA). Itaconate (ITA), an endogenous metabolite derived from the tricarboxylic acid (TCA) cycle, has attracted attention because of its anti-inflammatory, antiviral, and antimicrobial effects. This study evaluated the effect of ITA on FLS and its potential to treat RA. ITA significantly decreased FLS proliferation and migration in vitro, as well as mitochondrial oxidative phosphorylation and glycolysis measured by an extracellular flux analyzer. ITA accumulates metabolites including succinate and citrate in the TCA cycle. In rats with type II collagen-induced arthritis (CIA), intra-articular injection of ITA reduced arthritis and bone erosion. Irg1-deficient mice lacking the ability to produce ITA had more severe arthritis than control mice in the collagen antibody-induced arthritis. ITA ameliorated CIA by inhibiting FLS proliferation and migration. Thus, ITA may be a novel therapeutic agent for RA

    Validation of the Italian version of the spirituality and spiritual care rating scale (SSCRS‐ita)

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    Purpose: To translate and validate the Italian version of the Spirituality and Spiritual Care Rating Scale (SSCRS-ita). Methods: A single-center cross-sectional study was performed from October 15 to November 15, 2019 in a public hospital in Milan, Italy. The scale was drafted using the back-translation method. Prior to administration, the Italian version of the scale was assessed for content validity and retest stability by calculating the content validity index. Internal consistency was investigated by calculating Cronbach's alpha coefficient, test-retest stability by Spearman's rho coefficient. Findings: A total n = 337 nurses participated in the survey by correctly completing the scale. The Kaiser–Meyer–Olkin test (0.81) and Bartlett's test of sphericity (p&nbsp;&lt; 0.001) confirmed the adequacy of the sample to conduct exploratory factor analysis (EFA). The factorial model of EFA without rotation and then with nonorthogonal Promax rotation confirmed the presence of the four constructs identified by the original author. Conclusions: SSCRS-ita showed promising psychometric properties in terms of validity and reliability. The results of this study, together with the lack of in-depth studies in the Italian health and educational panorama, suggest the need to develop an educational pathway which, starting from the curricula of basic training and continuing with the updating of nursing staff, is dedicated to the detection of the spiritual needs of the patient. Implications for nursing practice: The SSCRS-ita is the first validated Italian tool concerning the consideration of the needs of spirituality and spiritual care in healthcare contexts; the possibility to use this tool is the first step towards a better integration of the mentioned dimensions of care in a nursing care qualitative perspective in Italy

    Learning motivation enhancement in Latvian language lessons's among 7th and 8th grades pupils

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    Runājot par latviešu valodu, 21. gs. ir laiks, kad tā tiek apdraudēta – mūsdienu jaunatne izvēlas komunicēt angļu valodā, šajā valodā lasa grāmatas, skatās filmas u.c. Arī latviešu valodas skolotāji apstiprina šādu teoriju, jo savā darbā saskaras ar tādām problēmām, kā piemēram, skolēni neievēro interpunkcijas un ortogrāfijas likumus. Ja ar skolēniem tiek runāts par mācību priekšmetiem, kuri viņiem patīk vislabāk, reti kurš min latviešu valodu. Kopumā skolēnos novērojams motivācijas trūkums un nevēlēšanās apgūt latviešu valodu. Šīs problēmas dēļ bakalaura darba autore Ita Vītiņa par sava darba tematu izvēlējās “Skolēnu mācīšanās motivācijas veicināšana iespējas latviešu valodas stundās 7. –8. klasē ”. Bakalaura darba mērķis ir analizēt mācīšanās motivācijas veicināšanas pedagoģiskās iespējas latviešu valodas stundās 7. -8. klases skolēniem. Lai noskaidrotu skolēnu mācīšanās motivācijas veicināšanas iespējas šajā vecumposmā, tika veikts pētījums. Pirmajā pētījumā solī piedalījās 55 skolēni. Viņiem tika piedāvāta N. Lukanovas anketa, kas paredzēta, lai noskaidrotu skolēnus, kuriem ir zems motivācijas līmenis, vai arī negatīva attieksme pret skolu, apkopojot anketas rezultātus atklājās, ka kopumā tādi ir 20 skolēni. Analizējot literatūras avotus, kas saistās ar mācību motivāciju, bakalaura darba autore nonāca pie trīs, viņasprāt, svarīgākajiem motivācijas veicināšanas nosacījumiem, kas ietekmē skolēnu mācīšanās motivāciju. Ņemot vērā šos mācīšanās motivācijas nosacījumus, tika papildināta pētījumā pirmā daļa jeb pirmais pētījuma solis, kurā 20 skolēniem, kuriem iepriekš tika noteikts zems motivācijas līmenis un negatīva attieksme pret skolu, tika piedāvāta bakalaura darba autores izveidota anketa. Apkopojot tās rezultātus, tika noskaidrots, ka skolēnu mācību motivāciju veicina individuālais darbs, kuru veicot, pusaudzis apzinās savu “es”, kā arī intereses radīšana. Pēc iegūtajiem datiem pirmajā pētījuma daļā, bakalaura darba autore izvēlējās konkrētu, vairākām mācību stundām paredzētu tematu, lai noskaidrotu, vai, piedāvājot šādu tematu, tiek ievērotas pusaudža vēlmes un intereses. Piedāvājot 55 skolēniem anketu, tika noskaidrots, ka šis temats ir aktuāls, tomēr, lai veicinātu mācīšanās motivāciju, to varētu integrēt ar vēsturi. Pētījuma kopējais apjoms ir 51 lapaspuses. Bakalaura darba pielikuma apjoms – 7 lapaspuses. Informācijas pārskatāmībai darbs papildināts ar grafisko materiālu – 9 attēliem. Kopējais bibliogrāfisko vienību skaits – 35 vienības.Speaking of the Latvian language in the 21st century it has come to a time when it is under a threat - modern youth prefer to communicate, read books, watch movies etc. in English language. Latvian language teachers also approve this theory because of the problems they are facing such as students more often do not observe the laws of punctuation and orthography in Latvian language lessons. If students are talking about the subjects, they like to study the most at school rarely anyone chooses Latvian language as they're favorite. In general, Students experience a lack of motivation and a reluctance to learn Latvian.Because of this problem, the bachelor thesis author Ita Vitina choosen the theme ''Learning motivation enhancement in Latvian language lessons among 7th and 8th grade pupils''. The aim of bachelor thesis is to analyze pedagogical possibilities of promoting learning motivation in Latvian Language Lessons for 7th and 8th grade pupils. To find out oppertunities to motivate students to study Latvian language at this age, a study was conducted. In the first step of the study 55 students participated. They were offered a survey by N. Lukanova to identify students with low motivation or negative attitude towards the school.Results of the survey revealed that is a total of 20 students. Analyzing literature related to study motivation, the author of the bachelor thesis came to three, in her opinion, the most important motivation promotion conditions that influence student learning motivation. Given these conditions of learning motivation, the first part or first of the study was supplemented a research step that offered 20 undergraduate students with previously low motivation and negative attitudes towards school a survey was created. Summarizing its results, it was found that the motivation of students to learn is facilitated by individual work, in which the adolescent becomes aware of his or her "I", as well as creating interest. Based on the data obtained in the first part of the study, the author of the Bachelor's Thesis selected a specific, multi-lesson topic to determine whether such a subject, the teen's wishes and interests are respected. By providing a survey to 55 students, it was found that this topic was relevant, but motivation could be integrated with history. The total volume of the study is 51 pages. Volume of the Bachelor – 7 pges. Thesis Supplement Work on transparency of information supplemented by graphic material - 9 images. The total number of bibliographic units is 35
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