1,313 research outputs found
Data for ''First simulations of day-to-day variability of mid-latitude sporadic E layer structures''
No full textOne file was added on July 21, 2020. (Caiondensity_average.nc)Two files were added on August 3, 2020. (ReadMe2_si_grl.pdf, S1.txt)The title was changed on August 3, 2020. (Before: Simulated Calcium Ion Density)One author was added on August 3, 2020. (Shinagawa Hiroyuki)ReadMe file was replaced on October 13, 2020.Two files were deleted on October 13, 2020. (ReadMe2_si_grl.pdf, S1.txt)Three files were added on October 13, 2020. (MeridionalWind_fig1.txt, VerticalWind_fig1.txt, ZonalWind_fig1.txt
Mid-Air Ultrasonic Stimulations of the Palm - The Influence of Frequency and Stimulus Duration on Perceived Intensity
No full textIt is known that the duration of a short stimulus affects the perceived intensity of both visual, auditory, and, vibrotactile events, but it is still unclear whether such a relationship also exists for mid-air ultrasonic inputs to the hand. Here we investigate this issue and show how the perceived intensity of focused ultrasonic stimulations of the palm is indeed systematically related to stimulus duration - a relationship that is, however, independent of modulation frequency. This is an important finding for the overall goal of providing perceptually stronger inputs and enlarging the repertoire of realistic mid-air haptic experiences.Human Information Communication Desig
The Effects of Dutasteride on Voiding and Storage Symptoms in Men with Benign Prostatic Hyperplasia
No full textWe investigated the effects of dutasteride on voiding and storage symptoms by a post-hoc analysis from two randomized, placebo-controlled, parallel-group studies (Japanese phase II study and phase III study) which assessed the efficacy and safety of dutasteride in Japanese men with benign prostatic hyperplasia (BPH). Men aged 50 years and older, with a prostate volume of 30 cc or greater, an International Prostate Symptom Score (IPSS) of 8 or higher and maximal urinary flow rate of 15 ml/sec or lower were randomized to placebo or dutasteride groups. The number of subjects for the placebo and dutasteride groups was respectively 72 and 72 in the phase II study, and 185 and 193 in the phase III study. Questions 1, 3, 5 and 6 of IPSS were related to voiding symptoms, and Questions 2, 4 and 7 were related to storage symptoms. Changes between pre- and post-treatments were evaluated. In the phase II study, dutasteride significantly improved voiding symptoms and numerically improved storage symptoms compared with the placebo at week 24. In the phase III study, dutasteride significantly improved voiding and storage symptoms compared with the placebo after 52 weeks. These consistent results suggest that dutasteride is effective for both voiding and storage symptoms in Japanese men with BPH
RFLNA遺伝子のフレームシフト変異をホモ接合性に認めた典型的な脊椎手根骨足根骨癒合症の一例
No full textSpondylocarpotarsal synostosis syndrome, a rare syndromic skeletal disorder characterized by disrupted vertebral segmentation with vertebral fusion, scoliosis, short stature, and carpal/tarsal synostosis, has been associated with biallelic truncating mutations in the filamin B gene or monoallelic mutations in the myosin heavy chain 3 gene. We herein report the case of a patient with a typical phenotype of spondylocarpotarsal synostosis syndrome who had a homozygous frameshift mutation in the refilin A gene (RFLNA) [c.241delC, p.(Leu81Cysfs*111)], which encodes one of the filamin-binding proteins. Refilins, filamins, and myosins play critical roles in forming perinuclear actin caps, which change the nuclear morphology during cell migration and differentiation. The present study implies that RFLNA is an additional causative gene for spondylocarpotarsal synostosis syndrome in humans and a defect in forming actin bundles and perinuclear actin caps may be a critical mechanism for the development of spondylocarpotarsal synostosis syndrome.長崎大学学位論文 学位記番号:博(医歯薬)甲第1200号 学位授与年月日:令和2年3月19日Author: Hitomi Shimizu, Satoshi Watanabe, Akira Kinoshita, Hiroyuki Mishima, Gen Nishimura, Hiroyuki Moriuchi, Koh-ichiro Yoshiura & Sumito DatekiCitation: Journal of Human Genetics, 64(5), pp.467-471, 201
Effects of rewarming therapies on outcomes in accidental hypothermia: A secondary analysis of a multicenter prospective study
No full text弘前大学博士（医学）Author(s): Kana Sugiyama, Osamu Nomura, Jin Irie, Yoshiya Ishizawa, Shuhei Takauji, Mineji Hayakawa, Yoshinori Tamada, Hiroyuki Hanad
Self-Sustainable Smart City Design on the Red Planet
No full textHiroyuki Miyajima, International University of Health and Welfare, JapanICES501: Life Support Systems Engineering and AnalysisThe 49th International Conference on Environmental Systems was held in Boston, Massachusetts, USA on 07 July 2019 through 11 July 2019.The author of this paper created a design process and design plan for a 1000 person Mars colony for the 2019 Mars Society contest. Particular attention was given to In-situ resource utilization and civil engineering, critical factors for constructing a substantial infrastructure for an almost completely self-sufficient colony. However, it is not possible to produce everything needed on Mars. To make the colony and its habitat self-sustaining and expandable as rapidly as possible, it is necessary to study multiple development schedules to determine the optimal weight of cargo per flight to be sent from Earth and the timing of when to send them, as well as, what should be produced on Mars to reduce the total resources needed. Therefore, our Mars colony development model created for analyzing the development schedule takes into consideration total mass transported from Earth to Mars, total resource mass obtained on Mars, the total energy required, and the total cost required. We determined the most feasible option would be using approximately 200,000 m2 of habitable area on Mars for a colony consisting of eight greenhouse domes with basement habitats built with resources found on Mars and brought from Earth
Life Support System Design for Habitation in Lunar Lava Tubes
No full textHiroyuki Miyajima, International University of Health and Welfare, JapanICES XXXXThe proceedings for the 2020 International Conference on Environmental Systems were published from July 31, 2020. The technical papers were not presented in person due to the inability to hold the event as scheduled in Lisbon, Portugal because of the COVID-19 global pandemic.In 2009, a large and deep hole, Marius Hills Hole (MMH), was discovered on the Moon with image data acquired by the Selenological and Engineering Explorer (SELENE) lunar probe’s terrain camera. SELENE radar sounder data also indicated a probable presence of lava tubes under the lunar surface in locations close to MMH. Lava tubes can provide shelter for human habitation from harsh environments, such as radiation, micrometeoroid, and the extreme temperatures of the lunar surface. The Japan Society for Aeronautical and Space Sciences (JSASS) Lunar Base Working Group has been tasked with devising a conceptual design for a manned lunar outpost inside the lava tubes reached via MMH. System configurations consisting of life support systems with biomass production systems, in situ resource utilization, and solar or nuclear power plants were designed and evaluated based on their feasibility to support a 100-person colony on the Moon over multiple decades. In accordance with the JSASS Space Exploration Roadmap guidelines, the author of this paper proposed a phased implementation scenario for building a lunar outpost inside lava tubes with the number of people living in it eventually increasing to 100 people with a food self-efficiency rate of 100 % by the 2050s
Life Support Systems Trade Study for Lunar Habitation with Greenhouse Food Production
No full textHiroyuki Miyajima, International University of Health and WelfareICES501: Life Support Systems Engineering and AnalysisThe 48th International Conference on Environmental Systems was held in Albuquerque, New Mexico, USA on 08 July 2018 through 12 July 2018.The Japan Aerospace Exploration Agency (JAXA) established the Space Exploration Innovation Hub Center called TansaX (Technology Advancing Node for SpAce eXploration) in 2015. TansaX specializes in technology research applicable to daily life as well as future lunar and Mars exploration. The author has been a member of the lunar farm group and its system design sub-group at the center since 2017. The author conducted a trade study to support lunar farm design by using a bioregenerative Life Support System (LSS) analysis tool and a life support system size analysis tool. This paper describes the analysis tools and the computational design procedures; in addition, an LSS design with the lunar farm for six crewmembers was analyzed. The initial mass, logistics mass, and Equivalent System Mass (ESM) of the LSS and its subsystems were compared. Increasing the utilization efficiency of mass and volume by increasing the vertical stacked layers of crops is recommended if the amount of crop cultivation is large, because the LSS initial mass can be decreased by this approach. The total mass value of the closed LSS with a downsized biomass production system was less than those of the open LSS and International Space Station (ISS)’s LSS after 600 days and 1,050 days of operation, respectively. However, the ESM value of the closed LSS with a downsized biomass production system was more than the ESM values of the open LSS and ISS’ LSS systems until 2,000 days and 3,950 days, respectively
Nonlinear dynamical systems and KCC-theory
No full textNonlinear dynamical systems can be uniquely investigated by a geometric theory (KCC-theory). The five KCC-invariants express intrinsic properties of the nonlinear dynamical systems. The second invariant as a curvature tensor determines the stability of the systems. The third invariant as a torsion tensor expresses the chaotic behavior. As an example, the KCC-theory is applied to a geodynamical system (the Rikitake system)
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