975 research outputs found
Karate Jutsu. Las enseñanzas originales del Gran Maestro Funakoshi
No full text[ES] Karate Jutsu, libro editado por Hispano Europea, se presenta con 160 páginas de esmerada y cuidada presentación con el subtítulo Las enseñanzas originales del Gran Maestro Funakoshi que es precisamente el autor del libro. Hay que aclarar que el original se titulaba Rentan Goshin Karate Jutsu. Hubiese sido de agradecer que la editorial hubiese conservado el nombre genuino de la obra, aunque sus razones tendrá para no hacerlo
Princípios Filosóficos e histórico do Karate-Do: conhecimento dos praticantes
No full textTCC (Graduação) - Universidade Federal de Santa Catarina. Centro de Desportos. Curso de Graduação em Educação Física.Este estudo teve como objetivo averiguar as informações absorvidas pelos karate-kas de duas academias de Florianópolis sobre o histórico, os princípios filosóficos e sua aplicabilidade. Participaram do estudo 22 karate-kas de duas academias de Florianópolis/SC, sendo que 20 eram do sexo masculino e dois do sexo feminino, a média de idade dos sujeitos da pesquisa foi de 32,59±9,66 anos; com média de tempo de prática de 7,72±6,35 anos, com a graduação dos karate-kas variando de amarela a preta. Como instrumento de medida utilizou-se um questionário, com questões abertas, testadas cientificamente, obtendo um índice de validação de 91,37%. Os dados foram trabalhados mediante a estatística descritiva em termos de frequência simples, bem como a estatística inferencial, com teste não-parametrico Qui-Quadrado, com probabilidade de 0,05. Os resultados mostram que com relação aos conhecimentos básicos do histórico do Karate-Do metade dos praticantes apresentaram conhecimento, já sobre um conhecimento mais relevante menos da metade apresentou algum conhecimento; quanto aos princípios filosóficos menos da metade dos entrevistados apresentou um pouco conhecimento. Poucos sabiam os mandamentos do dojo e a maioria relatou que o Karate-Do influencia no seu cotidiano. Pode-se concluir que há necessidade de serem abordados os princípios filosóficos do Karate-Do durante as aulas, haja vista os benefícios diretos e indiretos à vida dos praticantes
Human CD8+ T cells mediate protective immunity induced by a human malaria vaccine in human immune system mice
No full textAbstractA number of studies have shown that CD8+ T cells mediate protective anti-malaria immunity in a mouse model. However, whether human CD8+ T cells play a role in protection against malaria remains unknown. We recently established human immune system (HIS) mice harboring functional human CD8+ T cells (HIS-CD8 mice) by transduction with HLA-A∗0201 and certain human cytokines using recombinant adeno-associated virus-based gene transfer technologies. These HIS-CD8 mice mount a potent, antigen-specific HLA-A∗0201-restricted human CD8+ T-cell response upon immunization with a recombinant adenovirus expressing a human malaria antigen, the Plasmodium falciparum circumsporozoite protein (PfCSP), termed AdPfCSP. In the present study, we challenged AdPfCSP-immunized HIS-CD8 mice with transgenic Plasmodium berghei sporozoites expressing full-length PfCSP and found that AdPfCSP-immunized (but not naïve) mice were protected against subsequent malaria challenge. The level of the HLA-A∗0201-restricted, PfCSP-specific human CD8+ T-cell response was closely correlated with the level of malaria protection. Furthermore, depletion of human CD8+ T cells from AdPfCSP-immunized HIS-CD8 mice almost completely abolished the anti-malaria immune response. Taken together, our data show that human CD8+ T cells mediate protective anti-malaria immunity in vivo
Summary of the Optics, IR, Injection, Operations, Reliability and Instrumentation Working Group
No full textThe facilities reported on are all in a fairly mature state of operation, as evidenced by the very detailed studies and correction schemes that all groups are working on. First- and higher-order aberrations are diagnosed and planned to be corrected. Very detailed beam measurements are done to get a global picture of the beam dynamics. More than other facilities the high-luminosity colliders are struggling with experimental background issues, mitigation of which is a permanent challenge. The working group dealt with a very wide rage of practical issues which limit performance of the machines and compared their techniques of operations and their performance. We anticipate this to be a first attempt. In a future workshop in this series, we propose to attempt more fundamental comparisons of each machine, including design parameters. For example, DAPHNE and KEKB employ a finite crossing angle. The minimum value of {beta}*{sub y} attainable at KEKB seems to relate to this scheme. Effectiveness of compensation solenoids and turn-by-turn BPMs etc. should be examined in more detail. In the near future, CESR-C and VEPP-2000 will start their operation. We expect to hear important new experiences from these machines; in particular VEPP-2000 will be the first machine to have adopted round beams. At SLAC and KEK, next generation B Factories are being considered. It will be worthwhile to discuss the design issues of these machines based on the experiences of the existing factory machines
- …
