328,330 research outputs found
NFCB marathon: WORT, circa 1976
No full textNFCB marathon: WORT, produced by WORT, is a program aired during the National Federation of Community Broadcasters' nationwide radio marathon, an event in which noncommercial alternative radio stations across the United States stop regular programming to ask listeners to pledge funds to alternative and community stations. In this specific program from WORT in Madison, Wisconsin, the station presents ‚ÄúThe WORT Sampler,‚Äù a condensation of the entire week‚s previous programing, featuring a hundred hours of programming consolidated into a half hour, circa 1976
NFCB marathon: WORT, circa 1976
No full textNFCB marathon: WORT, produced by WORT, is a program aired during the National Federation of Community Broadcasters' nationwide radio marathon, an event in which noncommercial alternative radio stations across the United States stop regular programming to ask listeners to pledge funds to alternative and community stations. In this specific program from WORT in Madison, Wisconsin, an announcer presents ‚ÄúThe WORT Sampler,‚Äù a condensation of the entire week‚s previous programing, featuring a hundred hours of programming consolidated into a half hour, circa 1976
Use of St John's wort (Hypericum perforatum L) in members of a depression self-help organisation: a 12-week open prospective pilot study using the HADS scale
No full textThe findings of randomised controlled trials confirm that St John's wort (Hypericum perforatum L) is effective in reducing symptoms in mild to moderate depression, but few studies have focused on the effect on anxiety symptoms. Most studies have employed observer-rated scales to measure treatment outcome, only few used self-rated scales. We sought to examine these issues in a cohort of members of the depression self-help organisation Depression Alliance UK (n= 39). Hospital Anxiety and Depression (HADS) scales were used at baseline, prior to St John's wort administration, and for subsequent assessments at weeks 4, 8 and 12. A subject-rated version of the Clinical Global Impression – Improvement (CGI-I) scale was employed at follow-up assessments. HADS scores were significantly reduced after taking St John's wort, particularly for those reporting milder depression and more severe anxiety. HADS scores compared well with patient improvement ratings, indicating the feasibility of use in this population. Controlled studies are needed in a larger cohort to examine these findings, before definitive conclusions can be made
The role of habitat gaps and oceanography on the biogeography and population genetics of rocky intertidal gastropods in the Bay of Biscay
No full textIn biogeography, patterns of species abundance, distribution, size, population genetics and morphology often do not follow simple latitudinal gradients – which are classically assumed in such “rules” as the abundant centre hypothesis and Bergmann’s rule. Rather, the biogeography of a species or groups of species are more likely to be associated with abiotic and biotic variables such as availability of suitable habitat, temperature, dispersal potential, and habitat specificity. However, previous biogeographic studies rarely go beyond simple pattern description, particularly for marine species. In this thesis, I find that regional patterns of abundance, distribution, size, morphology, and population genetics are often associated with regional and local differences in environmental and biotic variables, such as upwelling intensity, habitat availability, and intrinsic attributes of species ecology, such as their level of habitat specificity. For example, a lower availability of suitable habitat can result in a fragmented distribution and subsequently lower genetic connectivity for species dependent upon that habitat. Differing abundances and recruitment among localities may also affect intraspecific competition, so density-dependent interactions occur, resulting in smaller/larger individuals. This would not necessarily follow the classically assumed temperature-size rule of smaller individuals usually being found at higher temperatures. Within a species, differing growth rates and adaptations to environmental variables can result in local morphological variation.These biogeographic concepts are explored in depth using rocky intertidal species of the Bay of Biscay as a model system, which contains a 230 km habitat gap and regional variation in temperature unrelated to a latitudinal gradient. In Chapter 2, the almost complete mitochondrial genome of Steromphala umbilicalis is described in relation to other Vetigastropoda. By removing different genes, and using amino acid or nucleotide sequences, different phylogenies are generated. From this, it is proposed that selection mechanisms may be occurring. In Chapter 3, the population genetics of the congeners S. umbilicalis (habitat generalist) and S. pennanti (habitat specialist), are described over the sympatric portion of their range, using both a newly developed mitochondrial marker and microsatellites. By combining this information with abundance estimates, S. umbilicalis is shown to have a more continuous distribution and is more abundant, and therefore shows greater genetic connectivity than S. pennanti which has a more fragmented distribution and lower abundance. In Chapter 4, the abundances, size structures and distributions of S. umbilicalis, S. pennanti, Phorcus lineatus, Patella vulgata and Patella depressa are explored using multiple linear regression for environmental variables including sea surface temperature, air temperature, wave exposure, distance to the habitat gap, and adjacent rocky substrate. Sea temperature showed a positive relationship with P. depressa abundance and the opposite for P. vulgata. Subsequent density-dependent interactions in P. depressa resulted in smaller individuals being associated with higher abundance between localities, and between quadrats within localities for both Patella species. The habitat gap amplified the differences in abundance between the cool water region in northern France dominated by P. vulgata and the warm water Basque region dominated by P. depressa. In Chapter 5, the aspect ratio of S. umbilicalis is explored at the macroscale in relation to multiple environmental variables. Sea temperature shows the best relationship with aspect ratio, both with initial European data and an expanded dataset including museum specimens from the British Isles. Whilst the underlying mechanism is unclear, it may be linked to a decreased growth rate at higher temperature, resulting in a more pointed shell.This work throws new light on biogeographic patterns and processes, particularly regarding temperature around range centres. It has implications when considering the impacts of global warming, particularly in relation to rocky intertidal biogeography.<br/
Topics in acute respiratory distress syndrome: the patient needs our tender loving and care
No full textThis editorial introduces a four-part series on acute respiratory distress syndrome (ARDS) that will cover a wide range of related topics in reviews written by internationally renowned experts. The first part of this series will be published in this issue of the European Respiratory Review by Guérin [1] on the role of prone positioning. This will be followed by articles on the topics of: 1) the role of imaging in the diagnosis and management of ARDS; 2) the novel ventilatory aspects involved in managing patients with ARDS; and 3) how to manage a patient failing conventional ventilation with extracorporeal support, in particular, extracorporeal membrane oxygenation (ECMO)
Erwiderung auf L. Hermann's "letztes Wort" u. s. w.
No full textERWIDERUNG AUF L. HERMANN'S "LETZTES WORT" U. S. W.
Erwiderung auf L. Hermann's "letztes Wort" u. s. w. (83) (-
Avaliação pré-clínica da atividade do tipo antidepressiva de quatro preparações comerciais de Hypericum perforatum e a sua correlação com os teores de hiperforina
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em FarmacologiaPreparações comerciais de Hypericum perforatum (erva-de-São-João; ESJ) são bastante populares, de interesse comercial, e são estudadas cientificamente há muitos anos. Por outro lado, há um grande interesse em encontrar alternativas terapêuticas seguras e confiáveis para o tratamento da depressão e, neste contexto, a ESJ tem competido com sucesso pelo status de terapia antidepressiva padronizada. Na busca por um princípio ativo que possa ser responsabilizado pela atividade antidepressiva do Hypericum, vários compostos, principalmente os naftodiantronas (hipericina e pseudohipericina), o fluoroglicinol hiperforina (e seu derivado adhiperforina), além de diversos flavonóides (rutina, hiperosídeo, isoquercitrina, quercitrina, quercetina) têm sido extensivamente estudados. No entanto, não é possível, até o momento, atribuir a atividade antidepressiva da ESJ a somente um dos constituintes químicos presentes na planta. Na verdade, uma atuação sinérgica dos constituintes mencionados tem sido sugerida, embora os mecanismos de ação farmacológicos exatos ou as proporções ideais de constituintes permaneçam desconhecidos. Inúmeros estudos farmacológicos (pré-clínicos e clínicos) usando extratos totais da planta, assim como frações e constituintes isolados foram feitos nos últimos anos. O presente estudo difere destes estudos porque testa extratos comerciais de ESJ em modelos animais de atividade antidepressiva, em paralelo ao estudo dos constituintes químicos destes fitoterápicos, tentando correlacionar o efeito e os compostos dos produtos (quantitativa e qualitativamente). No estudo farmacológico foram usados dois modelos comportamentais validados para avaliar a atividade antidepressiva dos produtos comerciais, testes estes que predizem o efeito clínico de substâncias de diferentes grupos químicos: o teste da suspensão pela cauda (TSC) e o teste da natação forçada (TNF). Para a análise química e a avaliação quantitativa dos produtos comerciais de ESJ usamos um método de eletroforese capilar não aquoso. Nossos dados confirmam a atividade antidepressiva das quatro preparações comerciais de ESJ (pela redução do tempo de imobilidade em ambos os testes), assim como o perfil dos constituintes ativos de alguns extratos de Hypericum encontrados no mercado brasileiro (hiperforina e flavonóides - quercetina, rutina e isoquercitrina). Para verificar a especificidade do efeito observado, a atividade motora dos animais foi avaliada no teste do campo-aberto (CA) imediatamente antes de sua submissão ao TSC. Nenhuma diferença estatística foi encontrada entre o grupo controle e os experimentais em qualquer dos parâmetros observados no CA (locomoção horizontal e vertical), excluindo assim qualquer efeito estimulante (ou atividade sedativa) para os produtos testados. Não observamos diferenças significativas entre os diferentes produtos no que diz respeito à atividade antidepressiva, mas seu perfil fitoquímico é completamente diverso, o que indica que os diversos constituintes (hiperforina, flavonóides, etc) podem estar interagindo sinergisticamente para promoção da atividade antidepressiva
Representações dos trabalhos femininos nas fotografias da revista Kolonie und Heimat in Wort und Bild.
No full textTCC (graduação) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas, História.No final do século XIX, o imperialismo ampliou o domínio de alguns países europeus sobre o continente africano. Entre eles, a Alemanha logrou ter colônias entre 1884 e 1914. A Sociedade de Colonização Alemã foi uma das principais instituições que se empenharam para a construção de uma sociedade colonial branca e germânica em África. Também a sua Liga Feminina teve papel importante, notadamente ao se mobilizar para o envio de mulheres brancas para as colônias africanas. Nestas colônias, as mulheres alemãs trabalhavam, entre outras atividades, como professoras, governantas, secretárias, enfermeiras e domésticas em casas, no meio urbano, ou em fazendas, no meio rural. Os espaços do trabalho feminino eram compartilhados entre mulheres alemãs e africanas, além de eventuais mulheres bôeres. Este trabalho apresenta uma análise do trabalho feminino nas colônias alemãs a partir de fotografias da revista Kolonie und Heimat in Wort und Bild da Liga Feminina
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