1,720,968 research outputs found
PENGARUH PEMBERIAN JUS JAMBU BIJI (Psidium Guajava L) TERHADAP KADAR ION NITRIT DAN GAMBARAN HISTOPATOLOGIK PANUS SENDI ADJUVANT INDUCED ARTHRITIS TIKUS WISTAR Studi terapi adjuvant induced arthritis in vivo pada tikus strain wistar THE EFFECT OF GUAVA (Psidium Guajava L) JUICE ON NITRITE ION CONSENTRATION AND THE HISTOPATHOLOGY PANNUS APPEARANCE IN JOINT ADJUVANT INDUCED ARTHRITIS IN WISTAR RATS
Get PDFBACKGRAUND: Nitrite ion increases in adjuvant arthritis. It has been associated with the activities of nitrite oxide (NO). Nitrite oxide mediates inflammation and axidant, it is a progressive joint disease characterized by hyperplasia sinovial and invasion pannus associated with an destruction of bone and cartilage. Jambu biji (Psidium Guajava L) is known to be the source of antioxidant and antiinflamation. Aim: To find out the difference nitrite ion and histopathological feature of joint in adjuvant induced arthritis rats after administration of jambu biji (Psidium Guajava L) juice. Design and Method: An experimental study had been done using a randomized post test only control group. Twenty five Wistar rats were divided into 5 group. 2 control groups (K- and K+) and 3 treated groups (jambu biji juice 1 gr/day, 2 gr/day and 3 gr/day). Griess was used to assay nitrite ion serum and hematosilin Euosin to assay histopathological pannus of joint. One Way Anova test and mann Withney test were applied for data analysis. Result: A significant difference in nitrite ion was found among the treated groups (p:0,00 < 0.05), but not between the K+ group and 2 gr/day treated group. There is significant difference in pannus feature among the treated groups (p:0,01 < 0.05) to K- group, but not among aspirin and jus jambu biji 1-3 grams/day treated groups, . Conclusion: Jambu biji (Psidium Guajava L) juice shows an effect for nitrite ion in consentration and histopathology pannus appearance of joint in adjuvant induced arthritis.
Latar belakang: Pada Adjuvant induced arthritis (AIA) kaadar NO meningkat oleh inflamasi dan oksidan. Karateristik AIA seperti bengkak pada sendi, hiperplasia sinovium, pembentukan panus, dihubungkan dengan destruksi tulang dan kartiago. Jambu biji (Psidium Guajava L) mengandung fitonutrien yang diduga sebagai sumber antioksidan dan antiinflamasi. Tujuan: Mengetahui pengaruh pemberian jus jambu biji terhadap kadar ion nitrit dan gambaran histopatologik panus sendi adjuvant induced arthritis tikus wistar. Metode: Studi eksperimen laboratorik dengan desain randomized post test only control group pada 25 ekor tikus strain wistar. Sampel terbagi 5 kelompok yaitu kelompok K-; kelompok K+ (aspirin); P1 ( jus jambu biji 1 gram/hari); P2 (jus jambu biji 2 gram/hari) dan P3 (jus jambu biji 3 gram/hari). Dilakukan pemeriksaan ion nitrit serum sebagai gambaran aktivitas NO dengan metode Griess, gambaran panus sendi dengan pengecatan HE. Data dianalisis dengan One Way Anova test dan Kruskal-Wallis Test dengan derajat kemaknaan P0,05. Ada perbedaan gambaran histologik panus terhadap kelompok perlakuan dengan p = 0,01. Hasil uji Mann-Whitney diketahui kelompok kontrol (K-) berbeda dengan kelompok perlakuan aspirin (K+), perlakuan jus jambu biji 1 gram/hari, perlakuan jus jambu biji 2 gram/hari dan perlakuan jus jambu biji 3 gram/hari. Simpulan: Pemberian jus jambu biji berpengaruh dalam menghambat produksi kadar ion nitrit dan gambaran histopatologik panus sendi tikus Wistar yang didinduksi dengan CFA
Pengaruh Pemberian Jus Jambu Biji (Psidium Guajava L)Terhadap Volume Kaki dan Kadar Ion Nitrit Adjuvant Induced Arthritis Tikus Wistar
Get PDFThe effect of Psidium Guajava L juice on nitric ion level and swelling of the joint in adjuvant induced arthritis rats
Backgraund: Nitric oxide increases in adjuvant induced arthritis. It has been associated with the activities of nitrite oxide mediates
inflammation and axidant, it is a progressive joint disease. Characterized by swelling of the joint associated with an destruction of
bone and cartilage. Jambu biji (Psidium Guajava L) is known to be the source of antioxidant and antiinflamation.
Aim: To find out the difference volume joint and nitrite ion in adjuvant induced arthritis rats after administration of jambu biji
(Psidium Guajava L) juice.
Methods: An experimental study had been done using a randomized post test only control group. Twenty five Wistar rats were
divided into 5 group. 2 control groups (K- and K+) and 3 treated groups (jambu biji juice 1 g/day, 2 g/day and 3 g/day). Volume
joint to assay mercury placement pletismography Griess was used to assay nitrite ion (activity NO) serum. One Way Anova test and
mann Withney test were applied for data analysis.
Results: A significant difference in volume joint between the treated groups. A significant different nitrite ion was found among the
treated groups (p<0.05), but not between the K+ group and 2 g/day in 3 cc treated group.
Conclusions: Jambu biji (Psidium Guajava L) juice shows an effect for volume joint and nitrite ion in consentration in adjuvant
induced arthritis
Identifikasi Nilai Oksidasi Minyak Goreng Yang Digunakan Oleh Pedagang Kaki Lima Di Kota Kendari
No full textIdentifikasi Nilai Oksidasi Minyak Goreng Yang Digunakan Oleh Pedagang Kaki Lima Di Kota Kendar
Pengaruh Konsentrasi Ekstrak Kunyit Dan Waktu Perendaman Terhadap Daya Simpan Dan Mutu Tahu
No full textPengaruh Konsentrasi Ekstrak Kunyit Dan Waktu Perendaman Terhadap Daya Simpan Dan Mutu Tah
Identifikasi Kandungan Fitokimia Jus Jambu Biji Merah Dengan Perlakuan Yang Berbeda
No full textIdentifikasi Kandungan Fitokimia Jus Jambu Biji Merah Dengan Perlakuan Yang Berbeda
Pengaruh Status Gizi Ibu Hamil Terhadap Berat Badan Lahir Bayi Periode Kelahiran Januari 2010-Mei 2011 Di RSU Provinsi Sulawesi Tenggara
No full textPengaruh Status Gizi Ibu Hamil Terhadap Berat Badan Lahir Bayi Periode Kelahiran Januari 2010-Mei 2011 Di RSU Provinsi Sulawesi Tenggar
Persepsi Doketer, Ahli Gizi, Dan Pasien Terhadap Pemanfaatan Poliklinik Gizi di Puskesmas Perawatan Abeli Kota Kendari
No full textPersepsi Doketer, Ahli Gizi, Dan Pasien Terhadap Pemanfaatan Poliklinik Gizi di Puskesmas Perawatan Abeli Kota Kendar
Efektifitas Program Makanan Pendamping Air Susu Ibu (MP-ASI) Pada Keluarga Miskin Terhadap Status Gizi Bayi Umur 6-11 Bulan Di Kota Kendari
No full textEfektifitas Program Makanan Pendamping Air Susu Ibu (MP-ASI) Pada Keluarga Miskin Terhadap Status Gizi Bayi Umur 6-11 Bulan Di Kota Kendari
Hubungan Antara Rasio Lingkar Pinggan Dengan Lingkar Pinggul (RLPP) Dan Kebiasaan Mengkonsumsi Makanan Olahan Terhadap Kejadian Hipertensi Pada Pasien Rawat Jalan Di Rumah Sakit Umum Daerah Provinsi Sulawesi Tenggara
No full textHubungan Antara Rasio Lingkar Pinggan Dengan Lingkar Pinggul (RLPP) Dan Kebiasaan Mengkonsumsi Makanan Olahan Terhadap Kejadian Hipertensi Pada Pasien Rawat Jalan Di Rumah Sakit Umum Daerah Provinsi Sulawesi Tenggar
- …
