1,238 research outputs found
The Gothic threshold of Sabine Baring-Gould : a study of the Gothic fiction of a Victorian squarson
This thesis is a study of the Gothic fiction of Sabine Baring-Gould (1834-
1924), with particular attention given to Baring-Gould’s roles as squire and parson. I
have chosen to analyze two of Baring-Gould’s Gothic works, the novel Mehalah
(1880) and the novella Margery of Quether (1884), both which allow a particularly
profitable examination of the influence of Baring-Gould’s roles on his fiction.
In studying these texts I apply my theory of Gothic fiction as a particularly
modern genre built upon a "Gothic threshold," a meeting point of extreme opposites
which ambivalently contrasts and merges the categories of the modern and the
medieval.
In the first chapter I describe how Baring-Gould’s unique Hegelian-influenced
Tractarian philosophy influenced his creation of the dialectical setting of Mehalah. I
argue that because of this influence Mehalah should be recognized as a significant
contribution to the literature of the Oxford Movement.
In the second chapter I argue that Mehalah’s historical setting in the time of
the French Revolution and the influence of Wuthering Heights reinforce Mehalah’s
use of the “Gothic threshold” structure and contribute to its theme of ambivalent
progress.
In the third chapter I discuss the influence of Baring-Gould’s sermon-writing
on Mehalah and consider connections between Baring-Gould’s role as parson and the
novel’s botched marriage theme.
In the final chapter I discuss Margery of Quether as an innovation in the
Gothic and vampire tradition as perhaps the only Gothic work that directly dramatizes
the Land Law debate and presents that debate as a "Gothic" contest. I argue that
Margery channels Baring-Gould’s tensions as a landowner.
In the conclusion I argue that Mehalah and Margery display Baring-Gould’s
technique of constructing miniature Gothic battles that relate to larger confrontations,
and that the ultimate terror presented in these works is the conclusion of the battle
between ancient and modern forces
Validierung von Polyphosphat als wirksames Hämostyptikum im Vergleich zu kaolinbeschichteter QuickClot® Combat Gauze® bei arterieller Blutung am Schockmodell
Der Verblutungstod ist eine aktuelle und lebensgefährliche Problematik in der militärischen Traumamedizin und der prä-klinischen zivilen Patientenversorgung. Hämostyptika, blutungsstillende Präparate, werden eingesetzt, um den Verblutungstod zu unterbinden. Dennoch gibt es kein Präparat, welches allen Kriterien eines idealen Hämostyptikums entspricht.
In dieser Arbeit wurde die Anwendbarkeit und Wirksamkeit von Polyphosphat (PolyP) und QuickClot® Combat Gauze® (QCCG), bei arterieller Blutung und Volumenmangelschock am lebenden Organismus miteinander verglichen. Ziel war es, durch die Anwendung von genannten Präparaten eine suffiziente Hämostase der arteriellen Blutung zu erreichen und so den post-interventionellen Blutverlust zu verringern. Die Durchführung der Versuche erfolgte als randomisierte experimentelle Studie am Großtiermodell mit Schweinen. Parameter der Hämodynamik und Respiration sowie BGA, Blutgerinnung und kleines Blutbild wurden kontinuierlich erhoben. Mittels Flussmesssonde wurde die Flussgeschwindigkeit in der linken Arteria femoralis zu jedem Zeitpunkt des Versuches abgeleitet. Mittels einer 3,6 mm Gefäßstanze wurde eine arterielle Blutung der A. femoralis sinistra erzeugt und durch einen Blutverlust von ca. 800g-1000 g, und daraus folgend einem MAP <60 mmHg ein Volumenmangelschock erzeugt. Anschließend erfolgte die Applikation des Hämostyptikums (PolyP/ QCCG) auf der Arterie und die fünf-minütige Kompression bei 200 mmHg. Nach der Blutstillung folgte die post-interventionelle Beobachtungsphase zur Beurteilung der Wirksamkeit der Hämostyptika, nach Blutdrucksteigerung durch Volumensubstitution, mit HAES 6 % oder durch Katecholamin Gabe. Zur Verifizierung des Schocks wurde die Mikrozirkulation von parenchymatösen Organen, präund post-interventionell, durch die Anwendung der Mikrosphären Methode dargestellt. Das in dieser Studie getestete PolyP erfüllt die Kriterien eines idealen Hämostyptikums, besonders durch seine bioresorbierbaren und biodegradierbaren Eigenschaften. Die gewonnenen Ergebnisse zeigen, dass bei Hämostyptika-Applikation eine permissive Hypotonie, mit einem systolischen Ziel-Blutdruck von 80 mmHg eine Reduktion der Mortalität bewirkt. Durch den verhältnismäßig niedrigen Blutdruck kann sich das Blutgerinnsel, welches zur Hämostase führt, besser stabilisieren, bis eine chirurgische Versorgung möglich ist. In Zukunft sollten weitere Studien zur Wirksamkeit von PolyP durchgeführt werden, um das Produkt noch weiter zu verbessern.Hemorrhage is a life-threatening problem in trauma medicine and pre-hospital civil patient care. Hemostatic dressings are used to stop severe bleeding and thus can prevent patients from bleeding to death. Nevertheless, there is no hemostatic dressing that fulfills all criteria of an ideal hemostat. In this work the effectiveness of two hemostats, polyphosphate (PolyP) and QuickClot® Combat Gauze® (QCCG), was tested on pigs. The test subjects were inflicted an arterial bleeding and a volume depletion shock. The aim of this randomized experimental study was to use PolyP and QCCG sufficiently to stop the arterial bleeding und thus minimize and prevent postinterventional blood loss.
27 German domestic pigs were used to conduct this trial. Hemodynamics, respiratory parameters as well as ABG, blood coagulation and small blood count were constantly monitored. Using the transit time flow measurement method, the blood flow velocity of the left femoral artery was measured continuously. An arterial hemorrhage of the left femoral artery was made, using a 3.6mm vascular punch. Due to the lesion of the vessel a volume deficiency shock with blood loss of approximately 800g-1000g, and an MAP <600mHg was caused. Afterwards the hemostatic dressings, either PolyPor QCCG, were applied to the lesion directly with a compression of 200mmHg for the following five minutes.
After the hemorrhage control the post-interventional follow up time of 120 minutes began. The aim was to assess the efficiency of the hemostat after increasing the blood pressure by volume substitution or catecholamines. To verify the shock, the microcirculation of parenchymal organs, pre- and post-interventional, was measured and analyzed using the fluorescence microsphere method. The PolyP fulfills the criteria of an ideal hemostat, especially because of its biodegradable and bioresorbable properties. The results of this study show that in addition to the hemostatic dressing itself permissive hypotension, with a systolic blood pressure of 80mmHg, plays an important role leading to the reduction of mortality. Due to the relatively low blood pressure, the formation of a stable blood clot is assured until surgical care is provided. Future studies should focus on the efficacy of PolyP, to improve the product
Recommended from our members
De Lingua Sabina: A Reappraisal of the Sabine Glosses
This thesis offers a reappraisal of the Sabine glosses through the analysis of thirty-nine words, all glossed explicitly as Sabine in ancient sources ranging from the first century BCE to the sixth century CE.
The study of the Sabine glosses found in ancient grammarians and antiquarians goes back to the beginnings of Italic scholarship. Over time, two positions on the Sabine glosses have crystallised: (a) the Sabine glosses are evidence of a personal obsession of the Republican author Varro, in whose work many Sabine glosses survive, and (b) the Sabine glosses are true remnants of a single language of which little or no epigraphic evidence has survived.
By using the neogrammarian observation that sound-change is regular and exceptionless, it is possible to ascertain whether or not the Sabine glosses are likely to be from the same language. This thesis finds that the sound-changes undergone by the Sabine glosses show no broad agreement. The developments are characteristic of different languages – Latin, Faliscan and various Sabellic languages – and many changes are mutually exclusive. This consequently throws doubt on the assertion that the Sabine glosses are all taken from one language. Instead, the glosses should be seen as part of a discourse of the relationships between Romans, Sabines and Sabellic-speaking peoples.
During the Republic, Sabines were central to Roman myth, historiography and political rhetoric. As the Sabines were a distinct people in the Roman foundation myths, but were largely Romanised in the Republican present, they became a convenient bridge between Rome and the Sabellic-speaking peoples of Central and Southern Italy, to whom Greek and Roman writers ascribed myths tracing origin back to the Sabines. This continued into the Empire, when emperors such as Claudius and Vespasian utilised their (supposed) Sabine heritage to gain ideological capital. In light of this, the phenomenon of Sabine glosses cannot be seen as one man’s interest, but as a means of reflecting on Rome’s relations with Sabellic-speaking Italy
KOMPARASI SEJARAH DAN ANALISIS TEKS SABINE SCHMIDTKE
This study looks at the numerous studies of Islamic theology conducted by Western nations since the early nineteenth century. They studied Muslim thinkers' writings and brought them to the West. Initially, the study of the manuscript was general in nature, but later thinkers narrowed it down to a specific study. Sabine Schmidtke is a modern Orientalist who specializes in manuscripts of Islamic theology, particularly Mu'tazilah theology. In this study, the author employs the library research method to examine Sabine Schmidtke's books and journals on the relationship between Jewish Karaites, Shia theology and Mu'tazilah theology. Based on the author's research, Sabine's comparative historical and textual studies have revealed that the Shia school of thought and the Jewish Karaites sect have adopted Mu'tazilah thought, specifically the thought of Abu al-Husayn al-Basri. They not only adopted ideas, but they also copied and preserved writings found in Yemen in the form of manuscripts.
Keywords: Sabine Schmidtke, Jewish Karaites, Mu'tazilah
An in-silico look at alternative battery materials : using combined quantum chemical and molecular dynamics approaches to determine physicochemical properties of novel battery materials
author: Sabine U. Lerch, BScMasterarbeit University of Innsbruck 202
An in-silico look at alternative battery materials : using combined quantum chemical and molecular dynamics approaches to determine physicochemical properties of novel battery materials
author: Sabine U. Lerch, BScMasterarbeit University of Innsbruck 202
An in-silico look at alternative battery materials : using combined quantum chemical and molecular dynamics approaches to determine physicochemical properties of novel battery materials
author: Sabine U. Lerch, BScMasterarbeit University of Innsbruck 202
Evaluation des Spidergrafts im Tiermodell an thorakoabdominellen Aortenpathologien mit besonderem Augenmerk auf die Blutversorgung des Rückenmarks
Integration and analysis of the effects of an unnatural amino acid into transmembrane 4 of the Orai1 protein
Author Bc. Helene Sabine Gemeinhardt BSc.Masterarbeit Universität Linz 2023Arbeit nach Ablauf der Sperre auf den öffentlichen PCs in den Bibliotheken der JKU+Medizin abrufba
Validierung der Fluoreszenzangiographie für die intraoperative Beurteilung und Quantifizierung der Myokardperfusion
BACKGROUND: Intraoperative graft patency verification is of major clinical importance for quality control after coronary artery bypass grafting (CABG), especially if surgery is performed on the beating heart. This is one of the first reports of fluorescence coronary angiography (FCA) using the dye indocyanine green (ICG), a noninvasive technology for direct visualization of coronary arteries and myocardial perfusion.
METHODS: Twenty-five domestic pigs underwent FCA of the left anterior descending coronary artery (LAD). In the first group (n = 6 pigs), FCA was used to visualize the native coronary vessels and myocardial perfusion. In the second group (n = 8 pigs), 14 stenoses of various degrees and 4 total vessel occlusions were created by snares on different segments of the LAD, and FCA was used to visualize the effects of these obstructions. In the third group (n = 11 pigs) defined stenoses (25%; 50%, 75%, 100% flow reduction) on the distal part of the LAD were created by a custom-made screw occluder and determined using TTFM (transit-time-flow measurement). ICG was intravenously applied, and the heart was illuminated with near-infrared light emitted by laser diodes. The fluorescence emission was detected by an adapted charge-coupled device camera system. The images were displayed in real time on a high-resolution monitor. Subsequently, images obtained with FCA were correlated with fluorescent microspheres data (n = 11 pigs).
RESULTS: In all cases, high-quality FCA images of coronary arteries and myocardial perfusion were obtained. All stenoses resulted in an impairment of the myocardial perfusion visualized by FCA. Occlusion of the LAD or the diagonal branch resulted in a total perfusion defect of the corresponding anterior myocardial wall with immediate reperfusion after releasing the snare. Correlation between FCA and fluorescent microspheres in determination of myocardial perfusion was excellent.
CONCLUSION: With the fluorescence technique using ICG, visualization of blood flow in coronary vessels and myocardial perfusion, is feasible. FCA is a highly sensitive and reproducible method and an excellent technique for intraoperative quality control in CABG
- …
