169 research outputs found
Risteilyelämyksen suunnittelu lapsiperheille koronarajoitteiden aikana : case: Tallink Silja Oy
No full textTämän opinnäytetyön tavoitteena oli tutkia, miten risteilyelämys suunnitellaan lapsiperheille ottaen huomioon koronaepidemian aikaiset rajoitukset ja ohjeistukset. Tutkimus tehtiin Silja Serenadella syyskuussa 2020, viimeisellä risteilyllä ennen koronaepidemian takia tiukentuneita matkustusrajoituksia. Opinnäytetyön aihe tuli hyvin ajankohtaiseksi koronaepidemian aikana. Opinnäytetyöntekijä on lisäksi itse töissä laivalla perheiden ja ohjelmien parissa.
Tämän tutkimuksen pääkohderyhmänä olivat lapsiperheet risteilyasiakkaina. Opinnäytetyössä tutkittiin, miten yhtiö on toiminut koronaepidemian aikana ja miten näissä toimissa on onnistuttu. Tärkeää oli selvittää risteilyasiakkaina olleiden lapsiperheiden ennakko-odotukset sekä kokemukset risteilyn aikana sekä kuulla mahdollisia kehitysehdotuksia.
Tietoperustan aiheet olivat risteilyn toimintaympäristö, elämyksellisyys, asiakaskokemus, lapsiperhematkailu, matkailuturvallisuus ja -hygienia sekä tilankäyttö. Opinnäytetyön aineisto kerättiin strukturoidulla haastattelututkimuksella, jossa haastateltiin lapsiperheitä ja risteilyn henkilökuntaa. Haastatteluaineistoa täydennettiin havainnoimalla laivayhtiön toimintaa risteilyn aikana.
Tutkimuksen tuloksena voi arvioida, että risteilyasiakkaiden kokemus vastasi risteily-yhtiön suunnitelmaa. Aineisto osoittaa, kuinka laajasti Tallink Silja oli tehnyt toimenpiteitä tuvallisen mutta silti viihdyttävän risteilyn aikaansaamiseksi. Risteilyasiakkaat olivat pääosin tyytyväisiä kokemaansa. Risteilyasiakkaiden toiveet ja tarpeet koronaepidemian aikana liittyivät seitsemään tutkimuksessa löydettyyn teemaan: turvallisuus, hygienia, palvelut, tilankäyttö, ohjelma laivalla, ennakkoon saatu tieto sekä perheiden oma vastuu. Näistä hygienia, tilankäyttö, ennakkoon saatu tieto, sekä perheiden oma vastuu ovat aiemmista tutkimuksista poikkeavia ja ovat siksi koronaepidemiaan liittyviä erityispiirteitä, jotka on syytä ottaa huomioon risteilyä suunniteltaessa.The objective of this Bachelor’s thesis was to investigate how a cruise experience can be planned for families with children, considering the limitations and guidelines during the COVID-19 epidemic. The survey was conducted at Silja Serenade in September 2020, on the last cruise before the travel restrictions due to the COVID-19 epidemic were introduced. The topic of the thesis naturally came up during the pandemic and because the author of the thesis is working on board with families and programs.
The main target group of the cruise service in this study were families with children. The thesis examined which procedures the company Tallink Silja Oy has followed to adapt to the changing circumstances caused by the Covid-19 pandemic, and how it has succeeded in these actions. It was important to research the expectations of families before the cruise and what in general is important for the families in relation to the pandemic, as well to map possible development suggestions.
The topics of the theoretical framework are the operating environment of a cruise, experientialism, the customer experience, family tourism with children, tourism safety and hygiene, and the use of space. The thesis data were collected through an interview study with families with children and with the staff. The interview material was supplemented by observations during the cruise. The purpose was to scrutinize different perspectives of both cruise guests and staff on the planning of the cruise experience and its success.
The results show what procedures Tallink Silja Oy has taken due to the COVID-19 pandemic so that customers and staff could cruise safely on the waves of the Baltic Sea. The study also provided comprehensive information on customers’ wishes and needs on cruises during the pandemic. The customers were very satisfied with the cruise and therefore there were not many suggestions for improvement. It can therefore be stated that the cruise corresponded well to the company’s planning. The themes that emerged from the study were safety, hygiene, services, use of space, program on board, prior knowledge of corona pandemic and families’ own responsibility
„... ich liebte Gomer“ – Elazar Benyoëtz und Silja Walter: Solothurn 2003 – davor und danach
No full textDieser Beitrag beschäftigt sich mit der Begegnung des Deutsch schreibenden, israelischen Dichters Elazar Benyoëtz mit der Schweizer Dichterin und katholischen Ordensfrau Silja Walter bei ihrer gemeinsamen Lesung während der Solothurner Literaturtage 2003 in der St. Ursen-Kathedrale. Er schaut auf den Arbeitsprozess, ihren Briefwechsel und ihren Austausch über Silja Walters Interpretation der biblischen Frau Gomer aus dem Buch Hosea.This paper deals with the encounter between the German-writing, Israeli author Elazar Benyoëtz and the Swiss author and Roman-Catholic nun Silja Walter in connection with their poetry reading at the Solothurner Literaturtage (St. Ursen Cathedral, 2003). The article explores their working process, their correspondence, and their dialogue about Silja Walter\u27s interpretation of the biblical woman Gomer in the Book of Hosea
Many ways of communication: from <it>Helicobacter pylori </it>adherence to death, disruption, migration and escape
No full text(VLID)218461
Cell Communication and Signaling / The functional interplay of Helicobacter pylori factors with gastric epithelial cells induces a multi-step process in pathogenesis
No full textInfections with the human pathogen Helicobacter pylori (H. pylori) can lead to severe gastric diseases ranging from chronic gastritis and ulceration to neoplastic changes in the stomach. Development and progress of H. pylori-associated disorders are determined by multifarious bacterial factors. Many of them interact directly with host cells or require specific receptors, while others enter the host cytoplasm to derail cellular functions. Several adhesins (e.g. BabA, SabA, AlpA/B, or OipA) establish close contact with the gastric epithelium as an important first step in persistent colonization. Soluble H. pylori factors (e.g. urease, VacA, or HtrA) have been suggested to alter cell survival and intercellular adhesions. Via a type IV secretion system (T4SS), H. pylori also translocates the effector cytotoxin-associated gene A (CagA) and peptidoglycan directly into the host cytoplasm, where cancer- and inflammation-associated signal transduction pathways can be deregulated. Through these manifold possibilities of interaction with host cells, H. pylori interferes with the complex signal transduction networks in its host and mediates a multi-step pathogenesis.Gernot Posselt, Steffen Backert and Silja Wessle
The role and function of HtrA in the pathogenesis of "Helicobacter pylori" and "Listeria monocytogenes": characterization of the proteolytic activity and identification of novel host cell targets
No full text> proteolytic activity of "Listeria monocytogenes" HtrA Carmen M. Abfalter, Sabine Bernegger, Miroslaw Jarzab, Gernot Posselt, Karthe Ponnuraj and Silja WesslerIdentification of Desmoglein-2 as a novel target of "Helicobacter pylori" HtrA in epithelial cells Sabine Bernegger, Robert Vidmar, Marko Fonovic, Gernot Posselt, Boris Turk, Silja Wessler> novel FRET peptide assay reveals efficient "Helicobacter pylori" HtrA inhibition through zinc and copper binding Sabine Bernegger, Cyrill Brunner, Matej Vizovišek, Marko Fonovic, Gaetano Cuciniello, Flavia Giordano, Vesna Stanojlovic, Miroslaw Jarzab, Philip Simister, Stephan M. Feller, Gerhard Obermeyer, Gernot Posselt, Boris Turk, Chiara Cabrele, Gisbert Schneider & Silja Wesslersubmitted by Sabine BerneggerLiteraturverzeichnis: Blatt 135-162Kumulative Dissertation aus drei ArtikelnDissertation Paris-Lodron University of Salzburg 2021Abstract/Zusammenfassung in deutscher und englischer Sprach
The role and function of HtrA in the pathogenesis of "Helicobacter pylori" and "Listeria monocytogenes": characterization of the proteolytic activity and identification of novel host cell targets
No full text> proteolytic activity of "Listeria monocytogenes" HtrA Carmen M. Abfalter, Sabine Bernegger, Miroslaw Jarzab, Gernot Posselt, Karthe Ponnuraj and Silja WesslerIdentification of Desmoglein-2 as a novel target of "Helicobacter pylori" HtrA in epithelial cells Sabine Bernegger, Robert Vidmar, Marko Fonovic, Gernot Posselt, Boris Turk, Silja Wessler> novel FRET peptide assay reveals efficient "Helicobacter pylori" HtrA inhibition through zinc and copper binding Sabine Bernegger, Cyrill Brunner, Matej Vizovišek, Marko Fonovic, Gaetano Cuciniello, Flavia Giordano, Vesna Stanojlovic, Miroslaw Jarzab, Philip Simister, Stephan M. Feller, Gerhard Obermeyer, Gernot Posselt, Boris Turk, Chiara Cabrele, Gisbert Schneider & Silja Wesslersubmitted by Sabine BerneggerLiteraturverzeichnis: Blatt 135-162Kumulative Dissertation aus drei ArtikelnDissertation Paris-Lodron University of Salzburg 2021Abstract/Zusammenfassung in deutscher und englischer Sprach
A novel basolateral type IV secretion model for the CagA oncoprotein of Helicobacter pylori
No full textSilja Freudenberger: : uma aproximação político-epistemológica entre a filosofia de Gadamer e perspectivas feministas
No full textIn The Hermeneutic Conversation as Epistemological Model (FREUDENBERGER, 2003), Silja Freudenberger indicates similarities between Gadamerian hermeneutics and Anglo-Saxon feminist epistemology. In this text, it seems appropriate to attribute to the author the hypothesis that the approaches of both streams of thought display parallels that should be observed for understanding the – largely negative – reception of the first within the philosophical literature developed in alignment with the second. Under the assumption that this hypothesis is a key guideline for the development of Freudenberger's text, this effort is dedicated to reconstructing and critically analysing the argumentative path followed by the author. The motivation for carrying out this task is, first, making the solidity of a surprisingly marginal position in a certain region of feminist philosophical literature visible – namely, that according to which there is no necessary incompatibility between feminist thought and the guidelines central to Gadamer's hermeneutics; and, additionally, presenting certain remarks of historical and contextual nature that explain, to a certain extent, the marginal status of this position.Em The Hermeneutic Conversation as Epistemological Model (FREUDENBERGER, 2003), Silja Freudenberger indica semelhanças entre a hermenêutica gadameriana e a epistemologia feminista anglo-saxã. No escrito em questão, parece cabível atribuir à autora, com efeito, a hipótese de que as abordagens de ambas revelam paralelos cuja observação adequada é instrumental para a compreensão da recepção – em larga medida negativa – da primeira no seio da literatura filosófica desenvolvida em alinhamento à segunda. Sob a suposição da vigência dessa hipótese como diretriz chave do desenvolvimento do texto de Freudenberger, este esforço é dedicado à tarefa de reconstruir e analisar criticamente o percurso argumentativo nele trilhado pela autora. A motivação para que se leve a cabo esta tarefa é, em primeiro lugar, a visibilização da solidez de uma posição surpreendentemente minoritária em certa região da literatura filosófica feminista – a saber, aquela segundo a qual não há incompatibilidade necessária entre pensamento feminista e as diretrizes centrais da hermenêutica de Gadamer; e, adicionalmente, a exposição de certas observações de cunho histórico e contextual que explicam, até certo ponto, o estatuto minoritário dessa posição
- …
