11,198 research outputs found
TSE pathogenesis in cattle and sheep
No full textMany studies have been undertaken in rodents to study the pathogenesis of transmissible spongiform encephalopathies (TSE). Only a few studies have focused on the pathogenesis of bovine spongiform encephalopathy (BSE) and scrapie in their natural hosts. In this review, we summarize the most recent insights into the pathogenesis of BSE and scrapie starting from the initial uptake of TSE agents and crossing of the gut epithelium. Following replication in the gut-associated lymphoid tissues (GALT), TSE agents spread to the enteric nervous system (ENS) of the gut. Infection is then carried through the efferent fibers of the post-ganglionic neurons of the parasympathetic and sympathetic nervous system to the pre-ganglionic neurons in the medulla oblongata of the brain and the thoracic segments of the spinal cord. The differences between the pathogenesis of BSE in cattle and scrapie in sheep are discussed as well as the possible existence of additional pathogenetic routes
Kenneth Tse and Marian Lee in a Guest Artist Recital
No full textThis is the program for the guest artist recital featuring saxophonist Kenneth Tse and pianist Marian Lee. This recital took place on November 13, 2007, in the W. Francis McBeth Recital Hall
Chinese strategic thinking under Mao Tse-tung
No full textThis paper traces the development of the military and political strategies of the Chinese Communist Party, as systematised in Mao Tse-tung's Works and other writings attributed to him and as carried out in practice during the struggle for power in China. It shows how these strategies and tactics are applied, in suitably modified form and at different levels of sophistication, to the conduct of foreign relations by the Chinese People{u2019}s Republic. The author argues that, regardless of changes in the hierarchy, the Peking government's actions abroad will continue to reflect the politico-military approach ascribed to Mao Tse-tung, although much of its past policy has now been repudiated as due to distortion of Maoism by deviationist subordinate leaders. This is a welcome addition to the literature on contemporary China by an author with a wide knowledge of Asian affairs
Fables de la Chine Antique, Tome II
No full textThis book is half of the larger-format canvas-bound predecessor of the identically named paperback book I have listed under 1980/84. The first text here is on 79 there. The order of texts changes slightly from time to time. The illustrations are the same. The cover picture here is the mirror-opposite of the cover picture there: a man sits before a fire over which a spitted turtle is roasting. There is a curious difference in names, whether of people or places. Thus L'Homme Qui Avait Peur des esprits (3) starts there Au sud de Xiashu vivait un homme nommé Juan Shuliang. The author is listed as Xunsi. Here, some twenty years earlier, the sentence reads Au sud de Sciacheou vivait un homme nommé Kiuan Siun-liang. The author is listed as Siun Tse. Here the title is pasted onto the gray paper cover in a lovely vertical red stripe. See my comments there and in the paperback Spanish and English versions of the book.This is a hardbound book (hard cover)Language note: FrenchRetold and Illustrated by Alice Shirle
Reflections on "Grounded theologies’ : ‘Religion’ and the ‘secular’ in human geography," by Justin Tse
No full textReprin
Should less motion sensitive T2-weighted BLADE TSE replace Cartesian TSE for female pelvic MRI?
No full textTo prospectively compare the diagnostic performance of a non-Cartesian k-space sampling T2-weighted TSE BLADE sequence with a conventional T2-weighted TSE sequence in female pelvic organs.Journal ArticleSCOPUS: ar.jinfo:eu-repo/semantics/publishe
Prions and Transmissible Spongiform Encephalopathy (TSE) Chemotherapeutics: A Common Mechanism for Anti-TSE Compounds?
No full textNo validated treatments exist for transmissible spongiform encephalopathies (TSEs or prion diseases) in humans or livestock. The search for TSE therapeutics is complicated by persistent uncertainties about the nature of mammalian prions and their pathogenic mechanisms. In pursuit of anti-TSE drugs, we and others have focused primarily on blocking conversion of normal prion protein, PrP^C, to the TSE-associated isoform, PrP^Sc. Recently developed high-throughput screens have hastened the identification of new inhibitors with strong in vivo anti-TSE activities such as porphyrins, phthalocyanines, and phosphorthioated oligonucleotides. New routes of administration have enhanced beneficial effects against established brain infections. Several different classes of TSE inhibitors share structural similarities, compete for the same site(s) on PrP^C, and induce the clustering and internalization of PrP^C from the cell surface. These activities may represent a common mechanism of action for these anti-TSE compounds
Characterizing chaotic dynamics from simulations of large strain behavior of a granular material under biaxial compression
No full textAuthor name used in this publication: Tse, Chi K.2012-2013 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishedVoR allowe
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