1,471 research outputs found

    Preserved cellular immunity in smoldering acute leukemia

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    &#34;Smoldering acute leukemia&#34;, a variant of acute myelogenous leukemia, has been recognized with frequent incidence in recent years. This is chracterized by benign clinical course, poor physical findings, leukopenia and mild anemia in the peripheral blood, and apparent infiltration of abnormal myeloblasts in the bone marrow. Immunological studies of the host defence mechanism were made, because the pathogenesis of its &#34;smoldering&#34; course has never been well understood. Nine cases, seen during last 2 years, were investigated for immunological profile, especially the cellular immunity. Purified protein derivative (PPD) skin test, i.e., tuberculin test, was found to be positive in 8 of 9 cases (88.9%). Dinitrochlorobenzene (DNCB) sensitization test showed to be positive in 4 of 6 cases examined (66.9%). Peripheral lymphocyte balstogenesis by stimulating with phytohemagglutinin (PHA) was evaluated using the smear counting method. The blastoid lymphocyte ratio was 55% at the median value (range: 31-68%), compared with 63% in normal young control (age: 25-32) and 41% in normal aged control (age: 60-75). In this report, the cellular immunity in smoldering acute leukemia was proved to be preserved at the normal level and to be more competent than that in aged group. The preserved cellular immunity is considered to explain the phenomenon of &#34;smoldering&#34;, in other words, the exacerbating proliferation of leukemic cells is suppressed by immuno-surveillance system.</p

    Does re-design of the policies on housing finance and supply help to solve housing question of Turkey?

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    Housing is one of the major socio-economic problems in Turkey. Widespread spontaneous settlements in urban area may be accepted as the sufficient criterion for the level of housing question in Turkey. Additionally, there are important quality problems in existing housing units. This problematic structure may be also explained by the lack of efficient housing policies and housing finance system. It seems after 2003 that housing policy of Turkey is essentially based on the Housing Development Administration‟s (HDA) pragmatic approaches. In this context, we may argue that the current housing policy is one-dimensional and also would be unsustainable in some perspectives. In this experimental research, the author attempts to analyze limitations and clear/potential problems of the housing policies of HDA. We basically analyze whether affordable housing problem is minimize with alternative policies and required incentives. In this context, we review housing subsidies and PPPs as the instruments of alternative social/private rental housing supply models. In a broader perspective, the original contribution of this paper is to examine private rental housing, social rental housing, urban renewal, micro-finance and housing production of REITs as the alternative housing supply/finance models to improve affordable housing. We conclude that these alternative housing supply/finance models may improve housing affordability and hence minimize the housing question in Turkey, if they can optimally design and required incentives may meet by the central/local governments.Housing finance, affordable housing, Turkish housing policies, TOKI (Housing Development Administration)

    Special Issue of Papers arising from the 18th International Workshop on H-mode Physics and Transport Barriers (Princeton, USA, 2022)

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    Submitted for publication in Nuclear FusionThis Special Issue of Nuclear Fusion collects papers from the 18th International Workshop on H-mode Physics and Transport Barriers, known more commonly as the 'H-mode Workshop', which was jointly hosted from 20–23 September 2022 by Princeton Plasma Physics Laboratory, Princeton University, Massachusetts Institute of Technology and General Atomics. The workshop was held as a hybrid event, with the on-site activities based at Princeton's Andlinger Center in Princeton, New Jersey, USA. It was the latest in a series of nominally biennial workshops beginning in 1987 and which have been hosted in a number of world locations (San Diego, Gut Ising, Abingdon, Naka, Princeton, Kloster Seeon, Oxford, Toki, St. Petersburg, Tsukuba, Fukuoka, Garching, Shanghai)

    First observation of Bs → J/ψf0(980) decays

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    Using data collected with the LHCb detector in proton–proton collisions at a centre-of-mass energy of 7 TeV, the hadronic decay is observed. This CP eigenstate mode could be used to measure mixing-induced CP violation in the system. Using a fit to the π+π− mass spectrum with interfering resonances gives . In the interval ±90 MeV around 980 MeV, corresponding to approximately two full f0 widths we also find , where in both cases the uncertainties are statistical and systematic, respectively

    Theory of Halo Nuclei

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    Magic numbers for superheavy nuclei in relativistic continuum Hartree-Bogoliubov theory

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    The magic proton and neutron numbers are searched in the superheavy region with proton number Z = 100-140 and neutron number N = (Z + 30)-(2Z + 32) in the relativistic continuum Hartree-Bogoliubov (RCHB) theory with effective interactions NL1, NL3, NLSH, TM1, TW99, DD-ME], PK1, and PK1R. Based on the two-nucleon separation energies S-2p and S-2n, the two-nucleon gaps delta(2p) and delta(2n), the shell correction energies E-shell(p) and E-shell(n), the pairing energies E-pair(p) and E-pair(n). and the pairing gaps Delta(p) and Delta(n) Z 120, 132, and 138 and N = 172, 184, 198, 228, 238, and 258 are suggested to be the magic numbers within the present approach. The of-decay half-lives are also discussed. In addition, the potential energy surfaces of possible doubly magic nuclei are obtained by using the deformation-constrained relativistic mean field (RMF) theory, and the shell effects stabilizing nuclei are investigated. (c) 2005 Elsevier B.V. All rights reserved.Physics, NuclearSCI(E)46ARTICLE1-2106-13575

    Preliminary Report on The Great Hanshin Earthquake January 17, 1995

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    The Japan Society of Civil Engineers (JSCE) received in an extremely serious light the severe damage to various infrastructures, caused by the Hyogoken-Nanbu Earthquake, which occurred in early morning of 17th January. It immediately took the step of organising investigation teams and dispatched them to the disaster area with the aim of elucidating the causes of the damage and thus contributing to the progress of seismic engineering and to the implementation of disaster prevention measures. On the day following the occurrence of the earthquake, the First Study Team, headed by Prof. Jushiro Tamura of Nihon University, chairman of the JSCE Committee on Seismic Engineering, and consisting mainly of researchers in seismic engineering and structural mechanics, was sent to the area for an emergency survey of the damage to the infrastructures. This was followed by the formation and dispatch of the Second Team, headed by me (Prof. Hideo Nakamura of the University of Tokyo), on 22nd January, for a comprehensive survey of the structural and functional damage to and progress of restoration work on railways, roads, port facilities and lifeline utilities. This emergency symposium is being held to provide an opportunity for making brief presentations of the findings of these two study teams. The damage was sa extensive to a variety of structures and sa broadly spread one different areas, the further detailed studies and analyses will be required before any firm conclusions may be drawn on many of the items studied. The views presented here are, in a large number of cases, not consensual description by the Society, but the opinions of individual members of the study teams. However, I am sure that it is our duty to hold an emergency symposium and to make known to the public the findings as quickly as possible. To continue with the surveys on the damage and restoration work, a Third Study Team, headed by Prof. Minoru Matsuo of Nagoya University, was sent to the disaster area on 1st February. The JSCE will take steps to report the findings of this and subsequent study teams at the earliest date possible. In addition, the JSCE will conduct detailed and systematic studies and analyses of the survey results, and present its findings to the public bath in Japan and abroad in the form of a "Report of the Study on the Great Hanshin Earthquake" . As members of the JSCE, we intend to devote the maximum amount of effort possible to restoration and reconstruction work in this wake of the earthquake and to the reduction of potential damage in future earthquakes. We entreat all those concerned to favor us with their cooperation and support to these ends.The Great Hanshin Earthquak
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