57 research outputs found

    Multicomponent Mechanical Characterization of Atherosclerotic Human Coronary Arteries: An Experimental and Computational Hybrid Approach

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    Atherosclerotic plaque rupture in coronary arteries, an important trigger of myocardial infarction, is shown to correlate with high levels of pressure-induced mechanical stresses in plaques. Finite element (FE) analyses are commonly used for plaque stress assessment. However, the required information of heterogenous material properties of atherosclerotic coronaries remains to be scarce. In this work, we characterized the component-wise mechanical properties of atherosclerotic human coronary arteries. To achieve this, we performed ex vivo inflation tests on post-mortem human coronary arteries and developed an inverse FE modeling (iFEM) pipeline, which combined high-frequency ultrasound deformation measurements, a high-field magnetic resonance-based artery composition characterization, and a machine learning-based Bayesian optimization (BO) with uniqueness assessment. By using the developed pipeline, 10 cross-sections from five atherosclerotic human coronary arteries were analyzed, and the Yeoh material model constants of the fibrous intima and arterial wall components were determined. This work outlines the developed pipeline and provides the knowledge of non-linear, multicomponent mechanical properties of atherosclerotic human coronary arteries.Medical Instruments & Bio-Inspired Technolog

    Ex vivo mechanical characterization of human atherosclerotic coronary arteries using inflation testing and finite element analysis

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    LAUREA MAGISTRALELA TESI CONSISTE NELLA CARATTERIZZAZIONE MECCANICA DI PLACCHE CORONARICHE PROVENIENTI DA DONATORI UMANI. IL LAVORO E' DIVISO IN DIVERSE PARTI. I CAMPIONI CORONARICI SONO PREPARATI, SUCCESSIVAMENTE VIENE ESEGUITO L'INFLATION TEST E LA ROTTURA DELLE PLACCHE E' DETETTATA DA DIFFERENTI TECNICHE DI IMMAGINI. LE MORFOLOGIE E I MATERIALI DELLE PLACCHE SONO IDENTIFICATI MEDIANTE MRI E MICRO-CT. INFINE VIENE RISOLTO IL METODO INVERSO AD ELEMENTI FINITI PER LA STIMA DELLE PROPRIETA' DEI MATERIALI DELLA PLACCA.THE THESIS CONSISTS IN THE MECHANICAL CHARACTERIZATION OF CORONARY PLAQUES FROM HUMAN DONORS. THE WORK IS DIVIDED IN DIFFERENT PARTS. CORONARY SAMPLES ARE PREPARED, THEN THE INFLATION TEST IS PERFORMED AND PLAQUE RUPTURE IS DETECTED WITH IMAGING MODALITIES. PLAQUE MORPHOLOGIES AND MATERIALS ARE IDENTIFIED WITH MRI AND MICRO-CT SCANNING. FINALLY, AN INVERSE FINITE ELEMENT PROBLEM IS SOLVED TO ESTIMATE PLAQUE MATERIALS PROPERTIES

    Subspaces Of Riemannian Spaces

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    In this paper, results obtained by the author for Riemannian Spaces Vn imbedded in Euclidean Spaces EN (3; 4) are extended to Vn imbedded in VN.The first section is introductory. In §2 the general result is obtained. This is the establishment of a certain dependency among the three basic sets of equations of the Vn with respect to the VN, namely the equations of Gauss, Codazzi and Kuehne.</jats:p

    'Negros indolentes' en las plumas de corógrafos: Raza y progreso en el occidente de la Nueva Granada de mediados del siglo XIX

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    In this article the images of the black are examined, as well as tehir associations with the notion of race and progress that are present in the landscapes of the works of two prominent members of the Corographic Commission, Agustín Codazzi and Felipe Pérez. The author arguments that it is necessary to make a detailed reading of these landscapes to untie certain assumption about the racial thinking of that time.Neste artigo são examinadas as imagens do negro e suas associações com a noção de raça e progresso que aparecem nas passagens das obras de dois destacados membros da Comissão Corográfica, Agustín Codazzi e Felipe Pérez. O autor argumenta que é necessário fazer uma leitura minuciosa destas passagens para desatar certas suposições sobre o pensamento racial da época.En este artículo se examinan las imágenes del negro y sus asociaciones con las nociones de raza y progreso que aparecen en los pasajes de las obras de dos destacados miembros de la Comisión Corográfica, Agustín Codazzi y Felipe Pérez. El autor argumenta que es necesario hacer una lectura detenida de estos pasajes para desatar ciertos supuestos sobre el pensamiento racial de la época

    The flag curvature of a submanifold of a Randers–Minkowski space in terms of Zermelo data

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    © 2022, The Author(s). This manuscript version is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by/4.0/ This document is the Published Manuscript, version of a Published Work that appeared in final form in Results in Mathematics. To access the final edited and published work see https://doi.org/10.1007/s00025-022-01661-0The main result of this paper is an expression of the flag curvature of a submanifold of a Randers–Minkowski space (V , F ) in terms of invariants related to its Zermelo data (h, W ). More precisely, these invariants are the sectional curvature and the second fundamental form of the positive definite scalar product h and some projections of the wind W. This expression allows for a promising characterization of submanifolds with scalar flag curvature in terms of Riemannian quantities, which, when a hypersurface is considered, seems quite approachable. As a consequence, we prove that any h-flat hypersurface S has scalar F-flag curvature and the metric of its Zermelo data is conformally flat. As a tool for making the computation, we previously reobtain the Gauss–Codazzi equations of a pseudo-Finsler submanifold using anisotropic calculus

    Goûts et saveurs livresques

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    International audience“Goûts et saveurs livresques” [“Bookish Tastes and Flavours”], Martina Della Casa and Paola Codazzi (Eds.), André Gide, aujourd’hui [Gide Today], Mulhouse, Mediapop, 2022, p. 21-23,Was the author of Les Nourritures terrestres a bon vivant? Not really, if we are to believe his diary: or at least, he was hardly a gourmand – and even fell into a (mild) form of anorexia towards the end of his life. How can we explain this contradiction between what he wrote and what he did? That is the guiding question of this article

    « Je ne sais s'il a écrit d'impérissables choses » : Gide vu par Jules Romains

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    International audience“Je ne sais s’il a écrit d’impérissables choses: André Gide vu par Jules Romains” [“I don’t Know if he wrote Anything Imperishable: André Gide as Seen by Jules Romains”], Paola Codazzi (Ed.), André Gide et ses critiques [André Gide, his Admirers and his Detractors], Paris, Classiques Garnier, submitted, to be published in 2024If we were to believe Jules Romains, André Gide would be: a man of influence... not very influential; a “classic” writer... but not “a classic”; an elder friend of young literature... or an old writer who would like to be one; a (clumsy) Machiavelli of the literary field; a grey eminence... more grey than eminent; a daring and singular author... but perhaps a bit of a plagiarist; an apostle of homosexuality... but who preaches in the wilderness

    “Mujeres blancas” en la Comisión Corográfica: una lectura fabuladora

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    "Mujeres blancas" (white women) is an image of the Corographic Commission of Agustín Codazzi in Colombia. The image represents, in the mid-nineteenth century, two light-skinned women dressed in European style, and a dark-skinned woman covered by a large mantle, the latter located at the back, and looking in the opposite direction. Speaking of a "fabling reading”, the author uses a narrative methodology that goes beyond the explicit content of the work to bridge gender, class, race and sexuality. This ancient image is used as a "pretext" to interrogate sociocultural dimensions that are still active today. The author questions, particularly, the role of the unnamed black woman in the process of construction of the white femininity and as a disguised erotic figure. She brings her presence as a hidden object from the white men’s desire, as a disobedient servant for the madams of the bourgeois houses, and as the mother-nurse excluded from the first infants’ erotic emotions. The conclusion of the article is in the Colombian society.Mujeres blancas es una imagen de la Comisión Corográfica de Agustín Codazzi en Colombia. Representa, en el medio del siglo XIX, dos mujeres de piel clara vestidas a la europea y una mujer de piel oscura revestida de un gran abrigo, situada detrás y mirando del otro lado. Hablando de una « lectura « fabuladora », la autora designa una metodología narrativa que va más allá del contenido explicito de la obra para cruzar género, clase, raza y sexualidad. Esta imagen del pasado está utilizada como un « pre-texto » para interrogar dimensiones socioculturales siempre activas hoy en día. La autora interroga más particularmente la función de la mujer negra innombrada en la construcción de la feminidad blanca y como figura erótica disimulada. Contempla su presencia como objeto escondido del deseo para los hombres blancos, como criada indisciplinada para las amas de casa y como la madre-nodriza forcluída de las primeras emociones eróticas infantiles. El artículo concluye con una reflexión sobre la performance de raza como performance de la clase dominante en la sociedad colombiana."Mujeres blancas" (mulheres brancas) é uma imagen da Comissão Corográfica de Agustín Codazzi na Colombia. Representa, em meados do século XIX, duas mulheres de pele clara vestidas em estilo europeu e uma mulher de pele escura coberta de um grande manto, localizada atrás e olhando para o outro lado. Falando de uma “leitura fabuladora”, a autora designa uma metodologia narrati vai além do conteúdo explícito da obra para cruzar com ggênero, classe, raça e sexualidade. Esta imagem do passado é utilizada como um “pretexto” para interrogar dimensões socioculturais ainda ativas atualmente. A autora interroga mais particularmente a função da mulher Negra anônima na construção da feminilidade branca e como figura erótica dissimulada. Ela examina sua presença como objeto escondido do desejo dos homens Brancos, como criada indisciplinada para as donas das casas burguesas e como ama de leite excluída das primeiras emoções eróticas infantis. A conclusão do artigo é uma reflexão dominante na sociedade colombiana."Mujeres blancas" (femmes blanches) est une gravure de la Comisión Corográfica de Agustín Codazzi en Colombie. Elle représente, dans le milieu du XIXème siècle, deux femmes à la peau claire vêtues à l'européenne et une femme à la peau foncée, recouverte d'un grand manteau, située derrière et regardant de l'autre côté. En parlant d'une "lecture fabulatrice", l'auteure désigne une méthodologie narr race et sexualité. Cette image du passé est utilisée comme un "pré-texte" pour interroger des dimensions socioculturelles toujours actives aujourd'hui. L'auteure interroge particulièrement la fonction de la femme Noire innommée dans la construction de la féminité blanche et comme figure érotique dissimulée. Elle examine sa présence comme objet caché du désir des hommes Blancs, comme servante indocile des maitresses de maison bourgeoises, comme mère-nourrice forclose des premiers émois infantiles. L'article se conclue par une réflexion su la classe dominante dans la société colombienne

    Business Practice Technical Supervision of the Construction and/or Optimization of Conduction and Distribution Networks of the Aqueduct System of the Urban Head of the Municipality of Agustin Codazzi Stage I - Department of Cesar

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    DigitalEn este documento se muestran los trabajos realizados por el autor durante la pasantía; apoyo en oficina y campo en la optimización de conducción y redes de distribución del sistema de acueducto de la cabecera urbana del municipio de Codazzi, además de la elaboración y actualización de documentación técnica-administrativa por iniciativa del Practicante, bajo la dirección del tutor encargado en del contratista ejecutor, ubicada en el municipio de Agustín, la cual posee como fin la transmisión y distribución de agua potable en el departamento del Cesar y algunos municipios de sus alrededores. Para lograr abastecer la demanda de agua potable, la Empresa debe llevar a cabo una determinada planificación que intensifique y garantice su capacidad, dando lugar a actividades en las cuales se ven involucrados los ingenieros civiles. Entre las acciones ejecutadas en la práctica se encuentra en análisis de diseños técnicos constructivos, estudio de planos y presupuesto inicial, la verificación de actividades realizadas en obra por la interventoría, realización de paquetes técnicos los cuales incluyen informes, cantidades de obra de las distintas estructuras que se encuentran en la red de distribución de agua potable, revisión, verificación y buena ejecución de los pactos plasmados en el contrato del proyecto, entre el departamento de planeación y el contratista ejecutante. Con la ejecución de la pasantía se lograron alcanzar resultados positivos para la formación como ingeniero civil y personas, comprendiendo cómo funciona una empresa encargada de suministrar un servicio público de distribución (agua potable), compartiendo tiempo e ideas con el personal de la empresa para mejorar la ejecución de las distintas actividades en una construcción, evaluando y tomando decisiones cuando se presenta un inconveniente en obra, momento que sirvió para ratificar el sentido de responsabilidad y compromiso que debe caracterizar a los ingenieros civiles en el desempeño de sus funciones.This document shows the works carried out by the author during the internship; support in office and field in the optimization of conduction and distribution networks of the aqueduct system of the urban head of the municipality of Codazzi, in addition to the preparation and updating of technical-administrative documentation at the initiative of the intern, under the direction of the tutor in charge of the executing contractor, located in the municipality of Agustín, whose purpose is the transmission and distribution of drinking water in the department of Cesar and some surrounding municipalities. In order to supply the demand for drinking water, the Company must carry out a certain planning that intensifies and guarantees its capacity, giving rise to activities in which civil engineers are involved. Among the actions carried out in practice is the analysis of construction technical designs, study of plans and initial budget, verification of activities carried out on site by the inspector, preparation of technical packages which include reports, quantities of work of the different structures that are in the drinking water distribution network, review, verification and proper execution of the agreements set forth in the project contract, between the planning department and the executing contractor. With the execution of the internship, positive results were achieved for training as a civil engineer and people, understanding how a company in charge of supplying a public distribution service (drinking water) works, sharing time and ideas with the company's staff to improve the execution of the different activities in a construction, evaluating and making decisions when an inconvenience occurs on site, a moment that served to ratify the sense of responsibility and commitment that should characterize civil engineers in the performance of their duties.Introducción 21 Identificación del Problema 23 Justificación 24 Objetivos 25 Objetivo General 25 Objetivos Específicos 25 Descripción General de la Empresa 26 Generalidad de la Empresa 26 Nombre y Ubicación 26 Objetivos de la Empresa 27 Misión 27 Visión 27 Estructura Organizacional 28 Políticas de Calidad 28 Política de Excelencia Organizacional 28 Práctica Empresarial 30 Localización del Proyecto 30 Datos Generales del Proyecto 31 Actividades Desempeñadas Ejecución del Proyecto 31 Localización y Replanteo 31 Levantamiento Topográfico 32 Maquinaria Implementada 33 Demolición en Pavimento Existente 34 Excavación de Zanjas 35 Retiro y Disposición Final de Escombros 36 Acopio de Materiales 37 Instalación de Tubería 39 Llenos Estructúrales Seleccionados 41 Ensayos de Laboratorio 41 Construcción de Cajas de Inspección 42 Tubería PF+UAD 43 Distribución Desde la Planta de Tratamiento 44 Red de Empalme 46 Ensayos de Compresion de Cilindros y Cono Slump 48 Curado 50 Análisis de Precios Unitarios 50 Informe Semanal Plasmado en un Bitácora 51 Manejo de Personal de Obra 52 Aportes del Estudiante 53 Conclusiones 54 Recomendaciones 55 Referencias Bibliográficas 56 Apéndices 58PregradoIngeniero(a) CivilUniversidad de Santande

    Plan Nacional de Cultura 2024 – 2038, cultura para el cuidado de la diversidad de la vida, el territorio y la paz.

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    Approaching Colombian cultural policies implies recognizing the various historical configurations around it. As a point of reference, the author Bravo (2014), historically dialogues and traces a line of cultural events. A first approach was constituted in the eighteenth century, in the colonial era with the research in natural history: Botanical expedition of the New Kingdom of Granada since April 30, 1783 sponsored by the Spanish crown and led by the Spanish physician, botanist, mathematician and priest, José Celestino Mutis. Its importance lies not only in the creation of a herbarium of more than 2,000 plants, a collection of plates and an astronomical observatory. This initiative, “was a fundamental milestone in the construction of the concept of nation, since the inventory of resources, and the description of the people contributed to the knowledge of the country and the appropriation of the cultural and social heritage” (Bravo, 2014, p. 50) which was then framed in the creation of the National Library in 1777 and the approach to geographical and cultural studies of the Italian Agustín Codazzi. &nbsp;Aproximarse a las políticas culturales colombianas implica reconocer las diversas configuraciones históricas entorno a la misma. Como punto de referencia, la autora Bravo (2014), dialoga históricamente y traza una línea de los acontecimientos culturales. Un primer acercamiento se constituyó en el siglo XVIII, en la época colonial con la investigación en historia natural: expedición Botánica del Nuevo Reino de Granada desde el 30 de abril de 1783 auspiciada por la corona española y liderada por el médico, botánico, matemático y sacerdote español, José Celestino Mutis. Su importancia no reside únicamente en la creación de un herbario de más de 2.000 plantas, colección de láminas y de un observatorio astronómico. Esta iniciativa, "fue un hito fundamental en la construcción del concepto de nación, pues el inventario de recursos, y la descripción de las gentes contribuyó al conocimiento del país y a la apropiación del patrimonio cultural y social" (Bravo, 2014, p. 50) que se enmarcó luego en la creación de la Biblioteca Nacional en 1777 y el acercamiento a los estudios geográficos y culturales del italiano Agustín Codazzi
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