1,720,966 research outputs found
AKTIVITAS SITOTOKSIK FRAKSI n-HEKSANA : KLOROFORM DARI EKSTRAK METANOL KULIT BATANG MANGROVE (Rhizopora mucronata) PADA SEL KANKER MYELOMA
Get PDFThe Mangrove plants have been long used for traditional medicine to cure gastroenteritis and cancer theraphy. Rhizopora mucronata, one species of Mangrove, is still rare studied that have potention as anti cancer. This research goals was to fractination bioactive compound of R. mucronata with various organic solvent and cytotoxicity test of those fraction n-heksana : chloroform to cancer cell myeloma. The extract from R. mucronata stem barks was made by maseration with methanol. The extracts was partitioned with chloroform, etil acetate, and methanol. The fraction of chloroform was fractination with n-heksana : chloroform (3 : 2). The fraction respectively was examined their cytotoxicity on Myeloma cell-line by MTT methods. Result showed that fraction n-heksana : chloroform from methanolic extract of R. mucronata stem barks was toxic on Myeloma cell, with the IC50 value was 15 µg/mLand phytochemical study showed that the active fractions contained flavonoid and terpenoid.Tanaman mangrove telah lama digunakan sebagai obat tradisional oleh masyarakat untuk terapi penyakit gastroenteritis dan antikanker. Rhizopora mucronata termasuk satu jenis mangrove yang belum banyak diteliti potensinya sebagai antikanker. Penelitian ini bertujuan untuk mengetahui aktivitas sitotoksik fraksi n-heksana: kloroform dari ekstrak metanol kulit batang Rhizopora mucronata pada sel Myeloma. Serbuk kulit batang R. mucronata diekstraksi dengan metanol dengan cara maserasi kemudian ekstrak metanol dipartisi berturut-turut dengan kloroform, etil asetat, dan metanol. Fraksi kloroform kemudian difraksinasi dengan campuran n-heksan dan kloroform (3 : 2) dan dilakukan diuji sitotoksisitas pada sel myeloma dengan metode MTT. Hasil penelitian menunjukkan bahwa fraksi n-heksana : kloroform dari ekstrak metanol kulit batang Rhizopora mucronata bersifat sitotoksik pada sel myeloma dengan nilai IC50 sebesar 15 µg/mL dan hasil uji kualitatif fraksi tersebut mengandung senyawa flavonoid dan terpenoid
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
EFEK ANTIHIPERURISEMIA FRAKSI-FRAKSI KAYA FLAVONOID BATANG BROTOWALI (Tinospora crispa) PADA MENCIT MODEL HIPERURISEMIA
No full textBrotowali (Tinospora crispa) secara tradisional dimanfaatkan untuk mengobati penyakit gout, artritis reumatoid, dan peradangan internal. Studi bioaktivitas dari batang brotowali menunjukkan efek antioksidan, antinosiseptif, dan antiinflamasi. Penelitian ini bertujuan untuk mengevaluasi efek antihiperurisemia dua fraksi dari ekstrak etanol batang brotowali pada mencit model hiperurisemia akut yang diinduksi potasium oksonat. Batang brotowali diekstraksi dengan etanol 70%, kemudian dipartisi secara berurutan dengan n-heksana, kloroform, dan etil asetat. Analisis fitokimia dilakukan dengan metode kromatografi lapis tipis, sedangkan kadar asam urat serum diukur dengan metode enzimatik-kolorimetri. Studi kami sebelumnya telah melaporkan bahwa ekstrak etanolik dan fraksi tidak larut n-heksana (FHITS) batang brotowali memiliki kandungan flavonoid yang tinggi. Pada studi ini, flavonoid tidak terdeteksi dalam fraksi kloroform (FKTS), namun ditemukan lebih dominan dalam fraksi etil asetat (FETS). Pada penelitian sebelumnya, ekstrak hidroalkoholik 500 mg/kg dan FHITS 100 mg/kg menunjukkan efek antihiperurisemia sebanding dengan allopurinol 10 mg/kg. Perlakuan fraksi kloroform dan fraksi etil asetat masing-masing dengan dosis 100 mg/kg pada mencit model hiperurisemia menunjukkan persentase penurunan kadar asam urat berturut-turut sebesar 39% dan 52%. Dengan demikian, ekstrak batang brotowali atau fraksinya yang mengandung flavonoid berpotensi digunakan dalam pengobatan hiperurisemia
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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