45 research outputs found
Manifestaciones oculares en pacientes con COVID-19: una revisión sistemática
Get PDFOBJETIVO: Actualizar la información sobre manifestaciones oftalmológicas
relacionadas con la enfermedad por SARS-CoV-2.
SUJETOS Y MÉTODOS: Esta revisión sistemática se centra en la relación entre la
enfermedad por COVID-19 y las manifestaciones oculares a través de una búsqueda
con las palabras clave SARS-CoV-2, COVID-19 y manifestaciones oculares obtenidas
de tesauros MeSH (COVID-19, eye manifestations) y DeCS (COVID-19,
manifestaciones oculares) y operadores booleanos (AND, OR, NOT) en bases de
datos y metabuscadores (PUBMED, BVS, Springerlink, EBSCO, ScienceDirect,
MedicLatina y TRIP), garantizando una recopilación completa de literatura científica
analizada mediante la escala OPMER y la escala GRADE.
RESULTADOS: Variedad de manifestaciones oculares y relacionadas con el sistema
visual en pacientes con COVID-19 afectando superficie ocular, párpados, fenómenos
vasculares e inflamatorios intraoculares e intraorbitarios a diferentes niveles del globo
ocular y sus anexos. Las manifestaciones oculares pueden variar en su incidencia y
gravedad en diferentes estudios, así como la posibilidad de transmisión ocular,
especialmente en entornos de atención médica.
CONCLUSIÓN: El seguimiento oftalmológico y la conciencia de las complicaciones
oculares en pacientes con COVID-19 son importantes para garantizar una atención
médica integral y oportunaInvestigadoresEstudiante
Formación continua y estrés académico de los oficiales alumnos del diplomado en liderazgo y gestión de la Compañía de Infantería en la Escuela de Infantería del Ejército - 2018
Get PDFEl objetivo de la presente investigación fue determinar cómo se relaciona la
formación con el estrés académico de los oficiales alumnos del Diplomado en Liderazgo y
Gestión de la Compañía de Infantería, en la Escuela de Infantería del Ejército - 2018,
desde la visión de los alumnos. El enfoque fue de una investigación cuantitativa, de tipo
descriptivo correlacional, de diseño no experimental, transversal. La población estuvo
compuesta por 100 alumnos, la muestra fue 80, a quienes se les aplicó dos instrumentos:
una encuesta de 6 preguntas con una escala de cinco categorías de respuestas referida a la
variable “formación continua”, confeccionada por el autor; y el Cuestionario de
Evaluación del Estrés Académico de De Pablo et al. (2002), con 18 preguntas adaptadas
para la Escuela de Infantería, con 4 alternativas de respuesta, tipo Likert, para la variable
“estrés académico”. El primer instrumento tuvo una alta confiabilidad de 0.938. Se realizó
el análisis correspondiente a los resultados de la encuesta llegando a la demostración
empírica de que el 88.9% apoya o considera positivamente los requerimientos de las
dimensiones e indicadores propuestos en el instrumento. Con el segundo instrumento se
determinó que sólo 13 alumnos (16.3%) están estresados, el restante 83.7% están algo o
nada estresados; esto fue ampliamente corroborado y contrastado empleando el chi
cuadrado. Se concluyó que la formación continua tiene relación significativa con el estrés
académico de los oficiales alumnos del Diplomado en Liderazgo y Gestión de la Compañía
de Infantería, en la Escuela de Infantería del Ejército - 2018.The objective of this research was to determine how training relates to academic stress among officer students of the Diploma in Leadership and Management of the Infantry Company at the Army Infantry School - 2018, from the students' perspective. The approach was a quantitative, descriptive-correlational, non-experimental, cross-sectional study. The population consisted of 100 students, the sample was 80, to whom two instruments were administered: a 6-question survey with a five-category response scale referring to the variable "continuing education," designed by the author; and the Academic Stress Assessment Questionnaire by De Pablo et al. (2002), with 18 questions adapted for the Infantry School, with 4 Likert-type response alternatives for the variable "academic stress." The first instrument had a high reliability of 0.938. An analysis of the survey results revealed that 88.9% of students support or positively consider the requirements of the dimensions and indicators proposed in the instrument. The second instrument determined that only 13 students (16.3%) are stressed; the remaining 83.7% are somewhat or not at all stressed; this was amply corroborated and verified using the chi-square test. It was concluded that continuing education has a significant relationship with the academic stress of officer students in the 2018 Diploma in Leadership and Management of the Infantry Company at the Army Infantry School.Universidad Nacional de Educación Enrique Guzmán y ValleTesi
Análisis de producción, impacto y redes de colaboración en investigaciones científicas en Scopus en Perú de 2000 a 2019
No full textIntroduction
Peru is a developing country with increasing scientific production. However, it is necessary to understand the trends, impact, and collaborative networks of research to plan for policy improvements.
Objective
We analyzed the production, impact, and collaboration networks in the Peruvian scientific production between 2000 and 2019.
Methods
We did an observational analytical study. We searched Scopus for all the publications with at least one author with a Peruvian affiliation declared in the author byline. A descriptive analysis of the different characteristics, trends, and scientific collaboration was carried out. Collaboration networks were plotted using VOSviewer.
Results
Between 2000 and 2019, Peru had a total of 24 482 publications in scientific journals, with an average annual growth of 13.6%. Of the total, 70% of all the articles were cataloged as Clinical Medicine and Biomedical Sciences. Only half of the articles had a Peruvian affiliation. The countries with the largest share of collaboration were the United States and Brazil, and the articles with international collaboration had the highest number of citations per publication.
Conclusions
Scientific production in Peru has increased in recent years, with a significant percentage of publications based on international collaboration and led by authors with non-Peruvian affiliations. It is necessary to strengthen collaboration ties between Peruvian and foreign institutions. Furthermore, it is essential to propitiate further research that will help solve the country's problems.El texto completo de este trabajo no está disponible en el Repositorio Institucional - Continental por restricciones de la casa editorial donde ha sido publicado
Violência contra gestantes: prevalência e fatores associados nas maternidades públicas de uma região metropolitana do sul do país
Get PDFTese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Saúde Coletiva, Florianópolis, 2014.O estudo em discussão refere-se à violência doméstica contra as gestantes que é aquela que ocorre em uma relação íntima.É dividida, quanto à natureza, em psicológica, física e sexual. Os objetivos são estimar a prevalência e fatores associados à violência doméstica em mulheres no período gestacional, identificar quais os tipos de violência (física, sexual, psicológica) a mulher sofre durante a gestação, avaliar o padrão de violência antes e durante a gestação e caracterizar o autor das agressões. A população de referência caracterizou-se por 753 mulheres puérperas, cujos filhos nasceram no período compreendido entre 01/03/2014 a 31/05/2014 e que estavam internadas nos setores de alojamento conjunto das Maternidades Públicas dos Hospitais da Grande Florianópolis, Santa Catarina. Realizou-se estudo transversal, por meio de entrevistas, face a face. Foi adotado questionário adaptado da organização Mundial da Saúde (OMS) denominado Estudo Multi- Países sobre Saúde da Mulher e Violência Doméstica(WHOVAW), validado no Brasil. As variáveis utilizadas foram: de interesse central(violência doméstica durante a gestação),demográficas(idade, cor da pele),socioeconômicas(escolaridade, trabalho atual, renda), relacionas à gestação(gravidez planejada, número de consultas, abortos), de comportamentos relacionado à saúde(uso de álcool, fumo, drogas),relacionados às situações de violência(brigas do casal, envolvimento em brigas com terceiros, violência em gestações anteriores, violência no último ano). A variável de interesse central foi correlacionada com as demográficas, socioeconômicas, de comportamentos relacionados à saúde, e,também, às situações de violência. Foram realizadas análises multivariadas. A prevalência de sofrer violência durante a gestação foi de 17,8%. A violência psicológica (17,5%), mostrou-se mais elevada do que a física (5,4%) e a sexual(0,1%). No que diz respeito ao padrão da violência, observa-se aumento da violência na gestação atual (17,8%), quando comparada ao ano precedente (3,1%). Observou-se que as variáveis que permaneceram mais fortemente associadas ao desfecho foram mulheres que já haviam sofrido violência nos últimos doze meses, que haviam sido agredidas em gestações anteriores, que faziam consumo de álcool, não brancas, que apresentavam transtorno mental comum e que não trabalhavam. Na caracterização do autor das agressões contra a mulher durante a gestação, a associação maior foi o consumo de álcool, uso de drogas, envolvimento em brigas, ter realizado agressões em gestações anteriores e ter agredido sua parceira na última gestação.Abstract : This study refers to domestic violence against pregnant women. This violence occurs in an intimate relationship and is divided to psychological, physical and sexual. The objectives are to estimate the prevalence and factors associated with domestic violence in women during pregnancy, identify what types of violence (physical, sexual, psychological) women suffer during pregnancy, to evaluate the pattern of violence before and during pregnancy and to characterize perpetrators. The study population was 753 puerperal women whose children were born in the period from 03.01.2014 to 05.31.2014 and who were hospitalized in the rooming sectors of Public Maternity Hospitals in Florianópolis, Santa Catarina. Using interviews, face to face across-sectional study was done with an adapted questionnaire from the World Health Organization (WHO), validated in Brazil named Multi-Country Study on Women's Health and Domestic Violence (WHOVAW). The interest central variable studied were: (domestic violence during pregnancy), demographic (age, skin color), socioeconomic (education, current employment, income), related to pregnancy (unplanned pregnancy, number of doctor visits, abortions), of health-related behaviors (alcohol use, smoking, drugs use), related to violence situation (couple fights, involvement in fights with others, violence in previous pregnancies, violence in the last year). The central interest variable was correlated with demographic, socioeconomic, health-related behaviors, and also to violence situation. Multivariate analyzis were performed. The prevalence of suffering violence during pregnancy was 17.8%. Psychological violence (17.5%), proved to be higher than the physical (5.4%) and sexual (0.1%). With regard to the pattern of violence, there is increasing violence in the current pregnancy (17.8%) compared to the previous year (3.7%). It was observed that the variables that remained more strongly associated without come were women who had experienced violence in the last twelve months, which had been battered in previous pregnancies, who were alcohol consumption, color skin not white, who had common mental disorders and did not had a job. In characterizing the author of assaults against women during pregnancy, the largest association was alcohol consumption, drug use, involvement in physical fights, done assaults in partner previous pregnancies and assaulting his partner in the last pregnancy
Humans with inherited MyD88 and IRAK-4 deficiencies are predisposed to hypoxemic COVID-19 pneumonia
Get PDFX-linked recessive deficiency of TLR7, a MyD88- and IRAK-4-dependent endosomal ssRNA sensor, impairs SARS-CoV-2 recognition and type I IFN production in plasmacytoid dendritic cells (pDCs), thereby underlying hypoxemic COVID-19 pneumonia with high penetrance. We report 22 unvaccinated patients with autosomal recessive MyD88 or IRAK-4 deficiency infected with SARS-CoV-2 (mean age: 10.9 yr; 2 mo to 24 yr), originating from 17 kindreds from eight countries on three continents. 16 patients were hospitalized: six with moderate, four with severe, and six with critical pneumonia, one of whom died. The risk of hypoxemic pneumonia increased with age. The risk of invasive mechanical ventilation was also much greater than in age-matched controls from the general population (OR: 74.7, 95% CI: 26.8-207.8, P < 0.001). The patients' susceptibility to SARS-CoV-2 can be attributed to impaired TLR7-dependent type I IFN production by pDCs, which do not sense SARS-CoV-2 correctly. Patients with inherited MyD88 or IRAK-4 deficiency were long thought to be selectively vulnerable to pyogenic bacteria, but also have a high risk of hypoxemic COVID-19 pneumonia.sponsorship: We thank the patients and their families for placing their trust in us. We warmly thank A. Dominguez-Acosta, P. Santana-Falcon, E. Rodriguez-Gonzalez, and M.E. Rosales-Bordon for technical assistance, and Y. Nemirovskaya, M. Woollett, D. Liu, S. Boucherit, C. Rivalain, M. Chrabieh and L. Lorenzo for administrative assistance. We are indebted to the "Biobanc de l'Hospital Infantil Sant Joan de Deu per a la Investigacio" for sample and data procurement and "Kids Corona Platform" Hospital Sant Joan de Deu, Barcelona. We would like to thank the members of the International IPF Genetics Consortium (https://github.com/genomicsITER/PFgenetics) for granting access to the genome-wide association studies summary data in the study across five cohorts, and to J.M. Aznar for providing data about mutations in RTEL1 in Spanish patients with IEI. We thank Erin Williams for organizing the logistics of patient samples and whole-exome sequencing. The graphical abstract was created with BioRender.com. The study was funded by Instituto de Salud Carlos III (COV20_01333, COV20_01334, PI16/00759, PI18/00223, PI19/00208, PI20/00876, and PI21/00211), the Spanish Ministry of Science and Innovation (RTC-2017-6471-1; AEI/FEDER), the Fundacion Canaria Instituto de Investigacion Sanitaria de Canarias (FIISC19/43 and FIISC22/27), Grupo DISA (OA18/017 and OA22/035), Fundacion MAPFRE Guanarteme (OA21/131), Cabildo Insular de Tenerife (CGIEU0000219140 and "Apuestas cientificas del ITER para colaborar en la lucha contra la COVID-19"), a 2022 Convocatoria de Beques de Recerca IRSJD-Carmen de Torres 2022 (2022AR-IRSJD-CdTorres), CERCA Programme/Generalitat de Catalunya, the Else Kroener-Fresenius Stiftung (EKFS, 2017_A110), the German Federal Ministry of Education and Research (01GM1910C), the Intramural Research Program of the National Institute of Allergy and Infectious Diseases, National Institutes of Health, and the Horizon Europe Framework Programme of the European Union under Grant Agreement no. 101057100. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Council Executive Agency. Neither the European Union nor the granting authority can be held responsible for them. (Instituto de Salud Carlos III, Spanish Ministry of Science and Innovation|COV20_01333, Spanish Ministry of Science and Innovation|COV20_01334, Spanish Ministry of Science and Innovation|PI16/00759, Spanish Ministry of Science and Innovation|PI18/00223, Spanish Ministry of Science and Innovation|PI19/00208, Spanish Ministry of Science and Innovation|PI20/00876, Spanish Ministry of Science and Innovation|PI21/00211, Fundacion Canaria Instituto de Investigacion Sanitaria de Canarias|RTC-2017-6471-1, Grupo DISA|FIISC19/43, Grupo DISA|FIISC22/27, Fundacion MAPFRE Guanarteme|OA18/017, Fundacion MAPFRE Guanarteme|OA22/035, Cabildo Insular de Tenerife|OA21/131, 2022 Convocatoria de Beques de Recerca IRSJD-Carmen de Torres 2022|CGIEU0000219140, CERCA Programme/Generalitat de Catalunya|2022AR-IRSJD-CdTorres, Else Kroener-Fresenius Stiftung (EKFS), German Federal Ministry of Education and Research|2017_A110, Intramural Research Program of the National Institute of Allergy and Infectious Diseases, National Institutes of Health|01GM1910C, Horizon Europe Framework Programme of the European Union, 101057100, National Institute of Allergy and Infectious Diseases|R01AI163029, National Institute of Allergy and Infectious Diseases|R01AI088364, National Institute of Allergy and Infectious Diseases|ZIAAI001265, National Institute of Allergy and Infectious Diseases|ZIAAI001270)status: Publishe
Author Correction: A detailed map of Higgs boson interactions by the ATLAS experiment ten years after the discovery
No full textNeutral pion production at midrapidity in pp and Pb–Pb collisions at √ sNN TeV
No full textInvariant yields of neutral pions at midrapidity in the transverse momentum range (Formula presented.)c measured in Pb–Pb collisions at (Formula presented.) TeV are presented for six centrality classes. The pp reference spectrum was measured in the range (Formula presented.)c at the same center-of-mass energy. The nuclear modification factor, (Formula presented.), shows a suppression of neutral pions in central Pb–Pb collisions by a factor of up to about (Formula presented.) for (Formula presented.) ≲(Formula presented.)c. The presented measurements are compared with results at lower center-of-mass energies and with theoretical calculations. © 2014, The Author(s)
Publisher Correction: Direct observation of the dead-cone effect in quantum chromodynamics (Nature, (2022), 605, 7910, (440-446), 10.1038/s41586-022-04572-w)
No full textIn the version of this article initially published, there was a typographical error in the first sentence following the “Exposing the dead cone” heading, now reading, “The measurements of R(θ), in the three radiator (charmquark) energy intervals 5 &lt; ERadiator &lt; 10 GeV, 10 &lt; ERadiator &lt; 20 GeV and 20 &lt; ERadiator &lt; 35 GeV…,” where “35 GeV” initially appeared as “3 GeV.” The error has been corrected in the HTML and PDF versions of the article. *A list of authors and their affiliations appears online. © The Author(s) 2022
Coherent ρ0 photoproduction in ultra-peripheral Pb-Pb collisions at √sNN=2.76 TeV
No full textWe report the first measurement at the LHC of coherent photoproduction of ρ0 mesons in ultra-peripheral Pb-Pb collisions. The invariant mass and transverse momentum distributions for ρ0 production are studied in the π+π− decay channel at mid-rapidity. The production cross section in the rapidity range |y| &lt; 0.5 is found to be dσ/dy = 425 ± 10(stat.)− 50 + 42 (sys.) mb. Coherent ρ0 production is studied with and without requirement of nuclear breakup, and the fractional yields for various breakup scenarios are presented. The results are compared with those from lower energies and with model predictions. © 2015, The Author(s)
Measuring (KSK +/-)-K-0 interactions using Pb-Pb collisions at root S-NN=2.76 TeV
No full textWe present the first ever measurements of femtoscopic correlations between the K-S(0) and K-+/- particles. The analysis was performed on the data from Pb-Pb collisions at root S-NN = 2.76 TeV measured by the ALICE experiment. The observed femtoscopic correlations are consistent with final-state interactions proceeding via the a(0)(980) resonance. The extracted kaon source radius and correlation strength parameters for (KSK-)-K-0 are found to be equal within the experimental uncertainties to those for (KSK+)-K-0. Comparing the results of the present study with those from published identical-kaon femtoscopic studies by ALICE, mass and coupling parameters for the a(0) resonance are tested. Our results are also compatible with the interpretation of the a(0) having a tetraquark structure instead of that of a diquark. (c) 2017 The Author. Published by Elsevier B.V
