8 research outputs found
Alternative Therapeutics Against Antimicrobial-Resistant Pathogens
No full textThis eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contac
Modelagem em hipermídia de um tutorial para criação de maquetes eletrônicas /
No full textDissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico
Ser down: ambiente hipermídia para o esclarecimento da síndrome de down
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro TecnológicoO nascimento de uma criança com Síndrome de Down, é muitas vezes um acontecimento embaraçoso para aqueles que a atendem. As dificuldades vão da habilidade para firmar o diagnóstico até a tranqüilidade para informá-lo à família, preparando-a para aceitar a criança e ajudá-la em seu desenvolvimento. Este trabalho é direcionado ao paciente Down e sua família buscando melhor atendê-los em suas necessidades de saúde. Mas se dirige principalmente ao profissional de saúde pois conhece-se a escassez de informações disponíveis sobre esta Síndrome, embora exista uma grande quantidade de informações médicas sobre esta doença em nosso meio, elas são pouco conhecidas por pais, voluntários e outros profissionais de saúde. Assim o Sistema de Hipermídia para o Esclarecimento da Síndrome de Down, visa contribuir para que o usuário iniciante ou não na área da informática, possa utilizar o computador na aprendizagem sobre esta Síndrome, bem como sua descoberta e principais característica
Overlapping signals for translational regulation and packaging of influenza A virus segment 2
No full textInfluenza A virus segment 2 mRNA expresses three
polypeptides: PB1, PB1-F2 and PB1-N40, from AUGs
1, 4 and 5 respectively. Two short open reading
frames (sORFs) initiated by AUGs 2 and 3 are also
present. To understand translational regulation in
this system, we systematically mutated AUGs 1–4
and monitored polypeptide synthesis from
plasmids and recombinant viruses. This identified
sORF2 as a key regulatory element with opposing
effects on PB1-F2 and PB1-N40 expression. We
propose a model in which AUGs 1–4 are accessed
by leaky ribosomal scanning, with sORF2 repressing
synthesis of downstream PB1-F2. However, sORF2
also up-regulates PB1-N40 expression, most likely
by a reinitiation mechanism that permits skipping of
AUG4. Surprisingly, we also found that in contrast to
plasmid-driven expression, viruses with improved
AUG1 initiation contexts produced less PB1 in
infected cells and replicated poorly, producing
virions with elevated particle:PFU ratios. Analysis
of the genome content of virus particles showed
reduced packaging of the mutant segment
2 vRNAs. Overall, we conclude that segment
2 mRNA translation is regulated by a combination
of leaky ribosomal scanning and reinitiation, and
that the sequences surrounding the PB1 AUG
codon are multifunctional, containing overlapping
signals for translation initiation and for segmentspecific
packaging
Object and feature based modelling of attention in meeting and surveillance videos
No full textMPhilThe aim of the thesis is to create and validate models of visual attention. To
this extent, a novel unsupervised object detection and tracking framework has been
developed by the author. It is demonstrated on people, faces and moving objects
and the output is integrated in modelling of visual attention. The proposed approach
integrates several types of modules in initialisation, target estimation and validation.
Tracking is rst used to introduce high-level features, by extending a popular model
based on low-level features[1]. Two automatic models of visual attention are further
implemented. One based on winner take it all and inhibition of return as the mech-
anisms of selection on a saliency model with high- and low-level features combined.
Another which is based only on high-level object tracking results and statistic proper-
ties from the collected eye-traces, with the possibility of activating inhibition of return
as an additional mechanism. The parameters of the tracking framework thoroughly
investigated and its success demonstrated. Eye-tracking experiments show that high-
level features are much better at explaining the allocation of attention by the subjects
in the study. Low-level features alone do correlate signi cantly with real allocation
of attention. However, in fact it lowers the correlation score when combined with
high-level features in comparison to using high-level features alone. Further, ndings
in collected eye-traces are studied with qualitative method, mainly to discover direc-
tions in future research in the area. Similarities and dissimilarities between automatic
models of attention and collected eye-traces are discusse
2
No full textTHE PALO ALTO TIMES
WEEKLY EDITION
FRIDAY, JULY 3. '8°6-
Th* Tims Ii KM a t
under President Arthur. Mr.I in history as (the chief author of
Teller left thc Sciiale'lcrtieHmieT^
la |>uMlilir<1 CHI) rnrl.) irmimw
Al palter,
•n Appllcal
&rrotu)-c!a)a*
AdvcHttlBK R>
TOM KKMI"
It appears that Pugilist Sharkey is not gifted as a talker. A
prize fighter who*docs not talk
better than he fights is certainly a
nit article, and Sharkey should
be put in a cage and exhibited as
a curiosity.
SAN Matbo is agitating the
question of building u bicycle
track. A like Improvement would
be of advantage to our own town.
A good bicycle track would not
only furnish amusement to thc
many local cyclers, but it would [the Republican platform, he bolted
bring business into the town, and {the party he had followed for forty
as a business proposition alone it) years.
Secretary of the Interior, returning to KIs old post after a three
years service In the Cabinet.
He is known M a skillful and
honest lawyer, and has been reasonably successful in business
ventures, uri&cipally silver mines,
in which he has been interested.
Though never a practical miner,
he claims to be *a good judge of
mines and he says that be has ex
amincd more of them than most
experts. He swears by Colorado
as the richest mineral State in the
Union.
In thc Senate Mr. Teller
looked'upon'as an authority on
Indian Territorial questions, but
is principally known as an
compromising advocate of the free
coinage of silver at thc ratio of
to t. He Iwlieves thc money-
question to be paramount to all
other issues, and rather than support the single standard plank .of
is worth considering.
Prrcv MlLi.nKBWV, who has had
charge of the Mountain View
Register for the past year, has sold
the plant to George Kenncy and
O. S. Walker, both of I,os Ciatos.
The new proprietors arc experienced newspaper men, and will
give tbe people of the Mountain
View section a wide awake and
rustling paper.
All voters should remember
that the Great Register tins been.
cuncellcd and a new one ordered
In person Teller is slender and
nervous, and not at all imposing,
He is a ready and earnest speaker,
but his voice is harsh, and irreverent newspaper critics have likened
his eloquence tolhcmusic of a buzx
SOW. But he is able and honest,
and if thc shifting about of political Standards during ih= present
campaign should place him in thc
age over President Hayes' veto ii
1B7B, has caused the Government
to Issue something like half a
billion of the "cart wheel" dollars.
la early life Mr. Bland spent j
several years on the Pacific Coast j
where he was interested in miti-
ing, and it was here that he got
his first ideas on silver.
Whoever gets'llie Democratic
nomination is sure to receive .it
with u silver tag attached.
at
DULLEY ESTATE.
Cash and Motaa Bequ—Uned. to Baal-
denta of Palo Alto.
Thc will of Mary B. Dulley.
deceased, was filed for probate
last I-"i id:iV by Charles J. Dulley of
Palo Alio. The estate consists of
8764.50 cash, and promissory notes
to the value, of 4064.50 Thc properly is bequeathed to five grandchildren,
one of whom is the petitioner.
The others arc Mary H.. Fred I...
Harriet R. and William B. Dulley.
Charles Dulley is named as
executor,
Thc hearing was set forvJuly
10th. J. H. Russell is attorney for
thc petitioner.
FERGUSON'S
STORK WIH XOT DE OPKX
SATURDAY JULY 4th,
A. S. J.
CLOSING OUT AT
COST
FOR THK NEXT 30 DAYS, ' WE OERSB OUR STOCK OF
STOVES. RANGES AND TINWARE AT
ABSOLUTE COST FOR CASH
MM If**
BL r. ttiJtMfcnl»*. rmprletar.
1 s t n 11. OopOriW tfce % T. Pr*%t Depot
Hit, GRAIN HO tlltiSTUrTS
WOOD »W COAL
Delivered at Lowcat Market Rales
Cmeral Eipraaa work
and Hauling Solicited
BEATTY'S
C ELK B A at* a
ORGANS AND PIANO*
For catalog***. kUrrm
tltNia P. lUTn\ Waihaujln. Xnr Jenrf
Junior Endeavor Enteetalnmant.
The Junior Kndeavor Society of I
the Presbyterian Church gave n
very pleasant entertainment ^Pri-
day evening. This organization i>
Presidential chair, thc American I growing tapidly under the encrge-1
people would have a Chief Magis-j tie superintendence of Miss Alice
tratc of whom they would have no
cause to he ashamed.
m k Otter.
compiled. It will he necessary for;
every voter to rc-rcgistcr during: What
the next few weeks or the privile- xhinka.*
ge of casting a ballot for Mckinley
and Gold cannot he enjoyed. -B. j
dept
this precinct and all voters?
should call u|hiii him al once.
A. H.\i.i.. thc well known
merchant, of San Jose,
has returned from the
East where he attended Ihc Si. Louis Convention
1 «s a delegate. Mr. Hale is one of
F.Hall is thc registration deputy * , , - . .
it he shrewdest and most far sighted
j business men in California, and
j his views'on (he political questions
No one should fail to attend the j of the day arc of much interest.
District School entertainment to! In a recent interview he said:
JUST OUT
THE STANFORD QUAD
For 1896
1
Weslall and the children arc tale-1
ing [much interest in the [work.!
The program Friday evening'
was well rendered and showed!
careful preparation. Miss Angicj
Hook gave a vocal" solo, accom-1 An elegant Book, a treasure for every Student, Ihc most interesting
panied by Miss Itcssic Kingorc on ***& Beautiful present vou can send to yonr friends. Concecded by al!
■ 1.. ..: it. 11 ..k» i-;»„„- 1.1 ■ to bet he finest eddition ever published. Secure a copv at once Iwfori
Ihc violin. Ilenha kingore. U1I.1 „, g, on|>. , Umil<y| m„„u.r ,,uWish^, "
llowse ami Edith U cslall recited mCaCUiat «»OS, Sole Agont, for >alo Alt.
in a very plcasinp manner. . ^—^— ^"^"^"j™-■™^^^—
Frank Stun aiing a wilo ami' Do yOU Intend Residing in
I'carl Carter. Mattic Don-mug
Mnry pawning. Eininu KiKipttmti
Altn Johnson, Georfffc rilL'Clelliili
Intend
iusl (I8!l(i) nut
New 1 *
* Process
Alto?
* Oil Stone
lw given at Nortree Hall. The! "Free silver is" a sectional|mid Reginald Ramsey rendered
program presented will Ik- unique, question upon which no national j a concert recitation. The-hit of
and it will be'interest ing from be-! party can unite, and protection is:the evening was made by Cora
ginning to end. Uncle John is in?thc rca' issue in this campaign.' Welsh in a recitation that was
the cast and is expected to add toj lender the Wilson Bill we arc to-[exceedingly well prepared for a* . r!1I!^ a full
his already high reputation as an j day importing millions of dollars.child of her age. | a ""'n,,. of
STQVES
products that should be ma nil- tnr<v. nf ilia nmaiani wire ilir- tnli-. w'i.v-
fact tired and raised in tihtSi»»u •*>*.«.>...« ...-. .......... ,» wiwmi __ , __^
country. To pay for these j Ruth Taylor and Clara Bnriiliiscl.yl jl/P \ I'lL ^t.tlhi GS
cput
amateur actor. and other! worth
performers of no mean abilities
will take part.
Palo
I r mi rail
LoUis Dalil
for your
Kitchen Rant
and Utensils
S.tMTlRV rmiBINf.
Many of our local contcmpo<
raries are complaining that their
towns nre in Tested Willi hordes of
tramps and depredations of one
Hi:ATINC '
A ■> Ull
I KtVKItMTY AVI:.
PALO - ALTO
of fabrics and other! One of the most pleasing fen-
manu- [lures of the program was the tab-1
[lean presented bv Alfred Weslall,
.IT
importations there is n drain of; Caroline Squire and Kingslcy
gold to Kuropc. Thereby gold is; PcasleyVniig in concert and the! muo Aiuto, c _
' withdrawn from the United States I entertain men.' closed with n song" u,l,n" Mlveu.ndo'ifl"hVr"ii«r«ni"r.'i.,. ■! .„'"i-'Jr,f,.ui.,..i,-»'iViii.
e theselhr the- PnloAlm Quartette Mm-. t—i*f can t»lt«. tha ff*|fffi,*fj£ •'^ WMMte Park
sort or another arc continually l>e-'obligations. This drain brings ■ posed of Messrs. Thomas. Slroticr. • " «-—_ _ T~ i~t> a~
ing committed. Thanks to the-about a necessity fur .an issue of j Doty and Wfelom. 'The Three, I D IlAT H\. *™l CStatC AgCflt BuSnRM?
vigilance of Constable Spauldinglionds so that we may borrow more Jews" was the title of their sclec-j I » a, J. 1/il ww X tXaOncas ^».ixrx> niiQOKa;
r. XI. Dnlcy
PnofRIKTOR
Mil I II.
our community is troubled but gold in order to restore thc reserve'tion and it was enthusiastically
very little with these pests. The 1 in the treasury lo its normal con- j received by the audience.
town of Palo Alio enjoys thc reputation among the "gentlemen of
the road" as being a place where
.vagruncy is not permitted mid the
average "hobo" gives it a wide
berth. All honor lo Old Sleuth
for this state of affairs.
d it ion
California needs protection for
our wines, prunes, raisins uud
other products. Under the
Wilson Hill it is even possible, at
Tbe Stanford Idea.
Cornell University has followed
the
has
•xatiiple set by Stanford, and
alrolishcd the degrees of
K.I I'll
INSURANCE,
Office and Residence Wear Depot Palo Alto, Gal.
present to bring liimlwr into the j bachelor of philosophy and
San Francisco market from British j bachelor of science. Only that of
t Columbia. | bachelor of arts is retained.
TllB people of Palo Alto arc to There if a general feeling of; Cornell has also adopted the
, be congratulated on Ihe fact that j confidence that wc arc sure soon; Stanford plan of free elcctivcs,ahc;
the local water works syslrm has j to have, better times. This con-! only exceptions lieing military i
been taken out of thc hands of C.j fidenceJb, brought about by the; drill mid physical culture which j
W.Jonesnnd is now under thejecrtain prospects for protection!Brc required of all students. A
ninnagementofa.compcteut man. with Ihe ascendancy .of the!wide liberty is allowed in the
For-thc past month Mr. Jones has Republican party, and then the choice of subjects for entrance
neglected his business and devoted monetary conditions will regulate {credits. •>
his time to squabbling and quarrel- j themselves." j The new policy makes Cornell
lug and as a result the water scr-' —~ ~ the most liberal of all universities
vice has. to express it mildly. I>ceu:TBKl>en^rntwNat.onal^nven-(in it5 trcatmcnl ofstud,.nis wi[b
far from satisfactory. The meter n, «»n meets; at Chicago .^ ^^ c ion of
appointed by the Superior Gomtrf£*nQtt*gk next week and thcjjn),itlu.i0,)
Mr. Frank Couden. is a gentleman I000"0"60- fight over Ihe choice 4m(, roun(c 0i|,
In whom every one has thc ut-!o("n standard bearer promises lobe
-must vuiifideiKC and hc-yHI apart 1" I'voly one. With-aJialf smrr of
nlie a Home eat&bllahment when needing
PLANTS
SEEDS
FRUIT TREES
SUNSET SEED &. PLANT COMPANY
PALO ALTO &
o pains to give the patrons of the'«-'«udidatcs already announced, and
Jones plant efficient service. j °* mart>' "niorc dnrk horses waiting
■"■— " > " ' ? [for thc lightening to strike, all at'
Tils dramatic* withdrawal of j tempts to pick the winners are
;aIfm_ Henry M. Teller from : useless, A few days agb itseemed
at. ihe Republican party that Teller might be taken up and
*>u*r* at the recent National j put fontard as a fusion candidate.
Convention has made him the most' but the rank and file of tbe D<
widely talked of num in American
public life today. Mr. Teller was
born in New York 111 Mny 1830.
■nd Is therefore sixty-six years of
age. He studied law and came
West at the age of 31 to take up
tbe practice of hi* profession.
His first appearamce in politics
cratic party will be satisfied, with
nothing less than a moss-back
Bourbon and Teller is out of the
question.
Just now "Silver Dick" BlancT
of Missouri appears to be in thc
lead. Blond is the.logical candidate of the supporter* of free silver
was in 1876 when he was the first, coinage His services to the cause
representative sent by the state of] of tbe white metal have been
Colorado to the United States Sen-j great, and he will be remembered
homt
The day of the old
with the'
traditional studies of
Latin and mathematics is about
over, and a quarter of a century
hence we shall see the pure
elective system as in ougurated at
Stanford adopted by all our
prominent universities.
Wm. C. LUND Proprietor.
"r j Carriages at all trains stopping at Menlo Park find Palo Alio Station
TrT. — ttith.compgtmu-DriwH-s. —
RED STAR STEAM LAUNDRY GO
We Employ .Only White Labor.
j. b. \.v.\y\an, pa«iD**T.
S. E MiCAUSTI.AND, Urberst An*nt, »*«Io Alto.
• ■ , S. B. BOPEtt, Agent, Knciaa Hat
p»lo Aito
HO^fifflRY
>lm. tU,.-li.- N.al», of 11,1. |ilirr, «aa
taken in Ihe niulit wild cratiirinsfaint,
and ilu> ni-xl ilnj Ui.irr)nn-a n-i in. sin-1
took hall a l-ultle uMilat'klM-rry cordial
but pa in. relief. Kin- tlirn rent to
me luae«Hl haJ anylliitic that mould Pm_—__ j. , , , ,. . 1
Itelp liar. 1 wnt hi-r a umkotHiRni- B,nOTon St- ™ *''" W*« Bolldlna;
herlaln'a Colli. Cliolcr.i and l>iarrho-«j Palo Alto, CaI.
K'-im-ilj mill 11"- llrat dutN* relievml her, j
Another ui our iipiplilturo had lawn aiek i
lor atumt a week oihI hod tri*il diH*n?nt «.._.,..,,.■.» m^.u^a. ,,, „„;tl,t I
reavadkH tor diarrhoea liut ke,.t pt>h«| Kvcrytbing made on the premises,
wow. I Hnt Mm this aame rraiedy., Bakinfal *ll kiivU (*r Umili*. >nd '-
Only tuur-doata ot It were rtu,uim! to Club Ilu>ta«« u< ofiW.
cor* liim. _H« ray a h* OWM lm recor-'
cry lo tin" woatkrtal retnedr. Vn.,
'larr Sibley. Hldrtay, Uieh. For tale; mtOWftBf*Utm*t9
T Hall'a Palo Alio Hiamaey. I lay.
.r»:'iii:v
rpiprlal
■ akaxl ■•ana mmS Boston
■ /
SEA BEACH HOTEL
Santa Cruz, Cal.
The most attractive
Seaside resort on Ihe
Coast. For terms, etc.
JOHN R. CHDE,""- Proprietor
WmT. Rhoads
Architect
Residence Plans a Specialty
1'AIA) Al.TU. UAU
TheOakTONSORiAL
PARLOR
The phut- for an easy Shave.
I ...r : ■ ..' '• II Ml CmOBf i-i-l MUfl: .'
Hail OuMitil tr..~ •* -hI. l»Mm> .ulrJ
Oj«« mt- - call. V*, V kLAIIK.
iit-|...iii rata Alio M.nk rraprtrlmr
Geo. W. Harms
General Blacksmithing
and Horseshoeing
Ropnli-lni ATnittly
r'roix.ptly riono
NVxl In PillBlHiry'a Cyclery PaloAllu.
hiioiMi
PALO ALTO. CAL.
n-rarmnun. • •
Jo*. Mmrainaon, - V
ft, H. rirklaMa,
niii-inin to no a
Ceneial Banking Business
Your Bu.ln... Solicited.
Furip rirluiw Bought idiI Sold
Hotel La Honda
Siliuli-I 111 a II. antihil t^oveol
(iifr-inii-a Sequoia, Inrrcaard
Camping Grounds. BeauMI
Drives. Superior Fishing and
Shooting. First Class Table
Maga liomllrilnn*! CHy Dally rtrcpl Sunalay
A.l.hm.rln.l.J Scat.
La HaaSa r>l
Special mluctioR to Uohrertity ftodenli
Elite Market
^yLSadajof-Jll^at
on liand. Game and I'o-.ilfy.
f»aaca> an. ih «alt paaa
Patronize
THE HOME MARKET
A. M. CARREL
HARNESS and
SADDLERY
Whips from 10c. up. Harness
from £to.oa up. Robcsand "Horse
Blankets from $1.50 up. Anything you may want In the Harness
and Saddlery line can lie found at
. i«iH"iinVti! hie
University are., Palo Ait
