183 research outputs found
Detection and diagnosis of carious lesions:Factual clinical approaches
No full textMinimal intervention dentistry is the accepted contemporary approach for caries management -both for the disease and the lesion. The development of adjunctive technologies to assist early lesion detection and quantifcation has led to the marketing of various devices over the past two decades. A thorough understanding of the clinical relevance of these devices is important to make precise interpretation of the information provided by the individual technologies. In this chapter, we will describe and discuss the most common commercially available carious lesion detection technologies in order to give dental practitioners clear information about the technology details and reliable and reproducible use of each device, its advantages and limitations, using a clinical approach.</p
Elodie Lawton Mijatovich’s translation of Bash Chalek; or true steel
No full textУ овом раду аутор анализира енглески превод популарне српске народне бајке Баш Челик, а аутор превода је Елоди Лотон Мијатовић. Аутор описује преводилачке технике и поступке које је Мијатовићева користила и анализира њихову оправданост. Још један битан елемент овог рада су и елементи изворне културе, при чему је укратко описано како их преводилац преноси циљној читалачкој публици. Чак и уколико се примене савремени стандарди, може се рећи да је квалитет овог превода изузетно висок.In this paper, the author analyzes Elodie Lawton Mijatović’s translation
of Bash Chalek, a popular Serbian folk tale. The author of the paper describes
translation techniques and procedures used in the translation and analyzes if they
are justified. Another important element of the paper are elements of the source
culture and a description of how the translator deals with them. It can be concluded
that the quality of the translation is excellent, even by modern standards
Advanced microscopy and diagnostic of carious lesion
No full textLa maladie carieuse a pour conséquence la déminéralisation de l’émail et de la dentine et la dénaturation du collagène de la dentine. En combinant la microscopie et spectroscopie multiphotoniques, nous avons démontré que l’intensité de la fluorescence (2-Photon Excited Fluorescence = 2PEF) et de la seconde harmonique (Second Harmonic Generation = SHG) de la dentine sont fortement modifiées pendant le processus carieux et nous avons découvert que le ratio SHG/2PEF est un paramètre fiable pour suivre le processus carieux. À présent nous souhaitons évaluer la sensibilité de la méthode en déterminant les limites des signaux mesurés pour détecter les premiers stades de la lésion carieuse. Nous avons noté une modification des spectres 2PEF de l’émail (à partir d’ICDAS (International Caries Detection and Assessment System) 1) et une modification des spectres 2PEF et SHG de la dentine (à partir d’ICDAS 2) dès les premiers stades du processus carieux. Nous avons également l’intention d’étudier la modification de la structure de la dentine lors du processus carieux grâce à la variation du signal de la SHG ; et plus précisément la (ou les) causes du « shift » vers le rouge du spectre de 2PEF observé lors du processus carieux. L’objectif serait une future application de ces signaux optiques dans le diagnostic clinique cariologique.Multiphoton microscopy and nonlinear spectroscopy is used to investigate caries process in dentin. Though a major calcified tissue of the teeth, the organic dentin phase comprises type I collagen fibers. Caries drive both dentin demineralization and collagen denaturation. Multiphoton microscopy is a powerful imaging technique because the biological materials are transparent to infrared frequencies and can be excited to penetration depths inaccessible to one photon confocal microscopy. The laser excitation greatly reduces photodamage to the sole focal region, and the signal to noise ratio is improved significantly. The method has been used to follow pathological processes involving collagen fibrosis or collagen destruction based on their 2-photon excited fluorescence (2PEF) emission and second harmonic generation (SHG). Combining multiphoton imaging with nonlinear spectroscopy we demonstrate that both 2PEF and SHG intensity of human dentin are strongly modified during tooth caries process and we discover that the ratio between SHG and 2PEF signals is a reliable parameter to follow dental caries. The ratio of the SHG/2PEF signals measured by nonlinear optical spectroscopy provides valuable information on caries process, specifically on the degradation of the organic matrix of dentin. The goal would be to bring these nonlinear optical signals to clinical application for caries diagnosis
Do decoupled payments really encourage farmers to work more off farm? A micro-level analysis of incentives and preferences
No full textAccording to neo-classical theory, farm operators’ labour allocation is determined by the relative wage they can earn from their labour on and off the farm. At the equilibrium, time should be allocated so that the marginal returns from on- and off-farm work are equal. Thus, a move from coupled to decoupled payments should have important impacts on labour allocation, as it reduces the return to farm labour and increases the unearned income of operators. However, empirical studies on decoupling have shown so far only limited impact from decoupling and sometimes contradictory findings. In this paper, individual preferences and constraints are taken into account to try and identify potential barriers to labour allocation adjustment. Empirical analysis based on the intentions to adjust to decoupling of a sample of French farmers confirms a limited impact of the change in policy and calls for further investigation of the potential barriers to adjustment.Decoupling, time allocation, farm operators, Agricultural and Food Policy, Labor and Human Capital,
Essais de caractérisation de la stathérine,protéine salivaire impliquée dans les pathologies parodontales et carieuses
No full textAIX-MARSEILLE2-BU Méd/Odontol. (130552103) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF
Marginalised Girlhood: Blind Spots, Challenges and Hopes
No full textTo marginalise is ‘to treat (a person, group, or concept) as insignificant or peripheral’ (Cambridge Dictionary). Marginalised Girlhood: Blind Spots, Challenges and Hopes opens the conversation about the representation of girls in popular culture along the axes of race, disability and sexuality. How does it feel to grow up at the periphery of the mainstream norms? To never have role models in dominant narratives; and to have one’s self-experience misrepresented? PhD candidates Elodie Silberstein and Belinda Glynn; and Dr Whitney Monaghan, author of the book Queer Girls, Temporality and Screen Media: Not 'Just a Phase' (Palgrave, 2016) will share their personal experiences in light of the current feminist resurgence. Join the conversation in a Q&A oriented session to have your say on how to empower the new generations of girls
Proposition d'une nouvelle classification des lésions cervicales pour une amélioration de la prise en charge des patients
No full textCervical lesions are common and their prevalence appears to be increasing. This accentuation is explained by greater functional longevity of the dental organ as well as changes in modern lifestyle. We have observed in the literature several classifications of caries lesions and wear lesions. However, it should be noted the lack of clinical and visual classification of cervical lesions. The new classification proposed in this work aims to redress this lack of information. This classification of carious and non-carious cervical lesions is based on their visual clinical appearance and their histological extent. A management cycle of these lesions is also propo-sed. The point of this study is to provide a standardized method in order to uniform and improve the detection, diagnosis and overall management of cervical lesions.Les lésions cervicales sont courantes et leur prévalence semble être en augmentation. Cette accentuation s’explique par une plus grande longévité fonctionnelle de l’organe dentaire ainsi que des changements de mode de vie moderne. Nous avons pu constater dans la littérature plusieurs classifications des lésions carieuses et des lésions d’usures. Toutefois, il est à noter un manque de classification clinique et visuelle des lésions cervicales. La nouvelle classification proposée dans ce travail a pour objectif de répondre à ce manque d’information. Cette classification des lésions cervicales carieuses et non carieuses est basée sur leur apparence visuelle clinique et leur étendue histologique. Un cycle de prise en charge de ces lésions est aussi proposé. L’intérêt est d’apporter une méthode standardisée, afin d’uniformiser et d’améliorer la détection, le diagnostic et la prise en charge globale des lésions cervicales
The complex genetic architecture of shoot growth natural variation in Arabidopsis thaliana
No full textOne of the main outcomes of quantitative genetics approaches to natural variation is to reveal the genetic architecture underlying the phenotypic space. Complex genetic architectures are described as including numerous loci (or alleles) with small-effect and/or low-frequency in the populations, interactions with the genetic background, environment or age. Linkage or association mapping strategies will be more or less sensitive to this complexity, so that we still have an unclear picture of its extent. By combining high-throughput phenotyping under two environmental conditions with classical QTL mapping approaches in multiple Arabidopsis thaliana segregating populations as well as advanced near isogenic lines construction and survey, we have attempted to improve our understanding of quantitative phenotypic variation. Integrative traits such as those related to vegetative growth used in this work (highlighting either cumulative growth, growth rate or morphology) all showed complex and dynamic genetic architecture with respect to the segregating population and condition. The more resolutive our mapping approach, the more complexity we uncover, with several instances of QTLs visible in near isogenic lines but not detected with the initial QTL mapping, indicating that our phenotyping accuracy was less limiting than the mapping resolution with respect to the underlying genetic architecture. In an ultimate approach to resolve this complexity, we intensified our phenotyping effort to target specifically a 3Mb-region known to segregate for a major quantitative trait gene, using a series of selected lines recombined every 100kb. We discovered that at least 3 other independent QTLs had remained hidden in this region, some with trait- or condition-specific effects, or opposite allelic effects. If we were to extrapolate the figures obtained on this specific region in this particular cross to the genome- and species-scale, we would predict hundreds of causative loci of detectable phenotypic effect controlling these growth-related phenotypes. Author summary The question of the complexity of the genetic variants underlying diversity in plant size and shape is central in evolutionary biology to better understand the impacts of selection and adaptation. In this work, we have combined the high resolution of a robotized platform designed to grow Arabidopsis plants under strictly-controlled conditions and the power of quantitative genetics approaches to map the individual genetic components (the 'QTLs') controlling diverse phenotypes, and hence reveal the so-called 'genetic architecture' of these traits. We show that the more we increase our resolution to map QTLs, the more complex of a genetic architecture we reveal. For instance, by focusing all of our mapping power on a small region representing 2.5% of the genome in an unprecedented phenotyping effort, we reveal that several independent QTLs had remained hidden in this region beyond a major-effect QTL that is always clearly visible. If this region is representative of the genome, this means that our current understanding misses potentially hundreds of variants finely controlling traits of evolutionary or agronomical interest
Multiphoton Microscopy for Caries Detection with ICDAS Classification
No full textDentin carious lesion is a dynamic process that involves demineralization and collagen denaturation. Collagen type I is the major protein in dentin and it has been investigated based on its optical properties. Multiphoton microscopy (MPM) is a nonlinear imaging technique that reveals the caries process using the collagen two-photon excitation fluorescence (2PEF) and its second-harmonic generation (SHG). Combining the histological and the International Caries Detection and Assessment System (ICDAS) classifications with nonlinear optical spectroscopy (NLOS), 2PEF and SHG intensities of enamel and dentin were highly altered during the caries process. It has been proven that the ratio SHG/2PEF is a relevant indicator of the organic matrix denaturation [Terrer et al.: J Dent Res 2016; 96: 574–579]. In the present study, a series of measurable signals is made to detect early stages of carious lesion according to the ICDAS classification and to explore the relationship between these measures and the ICDAS scale. Comparison of the efficiency of nonlinear optical signals for caries detection with the ICDAS classification is essential to evaluate their potential for clinical application. In our study, the use of the NLOS measured by MPM allowed us to monitor a quantitative parameter (SHG/2PEF ratio) according to the dentin carious lesion state (ICDAS and histological examination). Three coherent new groups were defined (ICDAS 0/1; ICDAS 2/3; ICDAS 4/5/6), where the carious process can be clearly described with a statistically significant decrease of the SHG/2PEF ratio.</jats:p
Datasets for replicating paper "Nitroaromatic Explosives detection and quantification using Attention-based Transformer on surface-enhanced Raman spectroscopy maps"
No full textThe datasets for replicating the paper "Nitroaromatic Explosives detection and quantification using Attention-based Transformer on surface-enhanced Raman spectroscopy maps". Detailed instructions about how to use the dataset can be found at: https://github.com/lyn1874/molecule_detection_and_quantification_vit
If you use this dataset, please cite:
@Article{D3AN00446E,
author ="Li, Bo and Zappalá, Giulia and Dumont, Elodie and Boisen, Anja and Rindzevicius, Tomas and Schmidt, Mikkel and Alstrøm, Tommy Sonne",
title ="Nitroaromatic explosives detection and quantification using attention-based transformer on surface-enhanced Raman spectroscopy maps",
journal ="Analyst",
year ="2023",
pages ="-",
publisher ="The Royal Society of Chemistry",
doi ="10.1039/D3AN00446E",
url ="http://dx.doi.org/10.1039/D3AN00446E",}
This item is part of the collection:
https://doi.org/10.11583/dtu.c.6434966 </p
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