136,042 research outputs found
Uma análise do tema saneamento básico nos livros didáticos de ciências do ensino fundamental no município de Florianópolis - SC
No full textTCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.Este trabalho teve como objetivo analisar a forma como o tema Saneamento Básico é abordado nos livros didáticos mais utilizados na Rede Municipal de Ensino de Florianópolis. Para isto, foi necessário identificar tais livros, o Ano em que este tema é mais abordado no Ensino Fundamental, assim como a proposição de critérios para análise. Os critérios foram elaborados após revisão da literatura referente à educação em Ciências e são: estrutura do tema; contextualização; relação com o desenvolvimento tecnológico; preocupação com Meio Ambiente; relação Homem/Meio Ambiente; Figuras e Ilustrações; e exercícios e atividades propostas. Os resultados deste trabalho não apontam livros bons ou ruins, mas apresentam e discutem aspectos relativos ao tema em tela, importantes para a formação dos alunos e que estão representados no livro didático. O trabalho propõe tratar de elementos que podem subsidiar a escolha de livros pelos professores
A drug safety evaluation of abiraterone acetate in the treatment of prostate cancer
No full textIntroduction: To evaluate the safety profile characteristics of abiraterone acetate (AA) in the treatment of metastatic prostate cancer (mPCa). Areas covered: In this literature review the authors evaluate safety data from phase III trials investigating the combination of abiraterone acetate plus prednisone (AAP) in patients with metastatic prostate cancer. In particular, the aim was to clarify its toxicity profile, long-term exposure impact, and the correlation with general health-related quality of life (HRQoL). Expert opinion: Based on the studies reviewed, it appears that abiraterone acetate has favourable outcomes, is effective and well tolerated, mostly in asymptomatic or slightly symptomatic patients, and has recognised toxicity profile characteristics. Incidence of adverse events (AEs), such as mineralocorticoid- and corticosteroid-releated AEs, and hepatotoxicity is well known and widely described. Understanding the toxicity profile of AA could assist decision-making in clinical practice
Mirafiori Motor Village
No full textConcept e progetto di rifunzionalizzazione di alcune architetture industriali site nell'insediamento torinese FIAT di Mirafiori, per la realizzazione di uno dei "più grandi spazi espositivi e commerciali d'Europa dedicati all'auto
Bibliographie Hilarion G. Petzold 1958 – 2009 mit Anhang als Einführung
No full textDieses Archiv enthält die Gesamtbibliographie der Werke des Autors nebst einiger Texte „Über H. G. Petzold“ im Schlussteil der Bibliographie sowie einen Anhang mit einer Einführung in die Architektur des Werkes in seinem wissenslogischen Aufbau als Ausarbeitung seines „Tree of Science Modells“ (2007).This archive contains the complete bibliography of the author and some texts about H. G. Petzold, moreover an epilogue with an introduction to the architecture of the works in its epistemological structure and composition and as an elaborations of Petzold’s „Tree of Science Modell (2007).https://www.fpi-publikation.de/polyloge/01-2009-petzold-h-g-gesamtbibliographie-h-g-petzold-1958-2009-updating-november2009/peerReviewedpublishedVersio
Laparoscopic ileocolic resection for Crohn's disease associated with midgut malrotation
No full textMidgut malrotation is an anomaly of fetal intestinal rotation. Its incidence in adults is rare. A case of midgut malrotation in a 51-year-old man with complicated Crohn's disease of the terminal ileum is presented. Symptoms, diagnosis, and treatment are reviewed. Preoperative workup led to correct surgical planning that ultimately allowed a successful laparoscopic resection
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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3346: Samuel G. Freedman, author, 2013
No full textPhotograph of author Samuel G. Freedman, at NT Daily Slash meeting in the Mayborn School of Journalism at UNT
L'approccio al tema
No full textLa ricerca su Abitudini e stili di vita dei ragazzi e delle ragazze a Palermo ha rappresentato un momento di riflessione, di studio e di indagine sul tema della povertà educativa. Partendo dal quadro disegnato dall’indagine desk, l’obiettivo principale dell’indagine field è stato quello di studiare empiricamente il territorio, in modo da individuare con maggiore analiticità i beneficiari ed i contenuti specifici da approfondire.
Per tale motivo, la ricerca è stata finalizzata ad approfondire il tema partendo dalle abitudini e gli stili di vita dei ragazzi e delle ragazze frequentanti le terze classi delle scuole secondarie di primo grado del territorio del Comune di Palermo, tenendo nello sfondo il tema della povertà educativa.
L’analisi dei concetti che in questa sede viene proposta non ha carattere di esaustività ma ha l’obiettivo di costruire una cornice di riferimento e di offrire spunti per future ri- flessioni. Per tale ragione, per ulteriori approfondimenti, si rimanda alla letteratura specifica sull’argomento.
Dal punto di vista metodologico, questa fase d’indagine si è avvalsa di strumenti di rilevazione diretta delle informazioni. La scelta di utilizzare una strategia di ricerca quantitativa ha comportato la formulazione e concettualizzazione dell’oggetto; la progettazione e costruzione della base empirica; il trattamento, l’elaborazione e l’analisi della base empiric
The urothelium, the urinary microbioma and men lUTS. a systematic review
No full textinTroDUcTion: The pathophysiology and management of male patients with lower urinary tract symptoms (lUTS) is still a matter of debate. in the past few years, the urothelium and the urinary microbiota represented important areas of research to improve the understanding and management of these patients. aim of the present review was to summarize the available data on the urothelium and the microbiota related to male lUTS. eviDence acQUiSiTion: a national center for Biotechnology information (ncBi) PubMed search for relevant articles published between January 2000 and December 2019 was performed using the medical subjects heading “urothelium,” “microbioma,” “microbiota,” “urobioma,” “urobiota,” “benign prostatic hyperplasia,” “benign prostatic enlargement,” “lower urinary tract symptoms,””lower urinary tract dysfunction,” “men,” “male,” “overactive bladder,””receptors.” exclusion criteria included: animal studies and studies on muscarinic and adrenergic pathways. eviDence SYnTHeSiS: The urothelium has been recently evaluated in humans to evaluate new possible markers and pathways. new possible targets for the treatment of male lUTS include the neural growth factor, the cannabinoid, the vanilloid and the aTP pathways. However, studies in humans are still needed to elucidate the exact role of these pathways in the management of male patients with lUTS. The available evidence on the urinary microbioma in male is poor. Standing to the available, urinary microbioma is evident in healthy urine in males. Moreover, the urinary microbioma varies depending on the method of collection, sexually transmitted disease status, inflammation and urinary symptoms. A possible role of probiotics in the management of lUTS in women has been proposed and may have a role in male patients as well. conclUSionS: The urothelium and the urinary microbiota are still poorly studied in men with lUTS. Most of the evidence and the hypothesis on the relationship between urothelium/urinary microbiota and lUTS comes from animal/ in-vitro evidence while clinical trials are lacking. These pathways seem interesting even in lUTS pathogenesis in men but their possible role as a new therapeutic target is still an open debate
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