102,184 research outputs found
A multiple-time-scale approach to the control of ITBs on JET
No full textThe simultaneous real-time control of the current and pressure profiles could lead to the steady state sustainment of an internal transport barrier (ITB), region where heat and particle transport are strongly reduced and so to a stationary optimized plasma regime. Recent experiments in JET have demonstrated significant progress in achieving such a control: different current and temperature gradient target profiles have been reached and sustained for several seconds using a controller based on a static linear model identification. Nevertheless, these experiments have shown that the controller was sensitive to rapid plasma events such as transient ITBs during the safety factor profile evolution or Magneto-Hydrodynamics (MHD) instabilities which modify the pressure profiles on the confinement time scale. The control technique has been improved by using a multiple-time-scale approximation in order to better respond to these rapid plasma events. The paper describes the theoretical analysis and closedloop simulations using the controller that will be tested experimentally in JET during the forthcoming campaign. © 2006 IEEE
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
New Azulene-Type Sesquiterpenoids from the Fruiting Bodies of Lactarius deliciosus
No full textAbstract In the 1H NMR-guided fractionation of extracts from the edible mushroom Lactarius deliciosus, two new azulene-type sesquiterpenoids, 7-isopropenyl-4-methyl-azulene-1-carboxylic acid (1) and 15-hydroxy-3,6-dihydrolactarazulene (2), together with seven known compounds were characterized. Their structures were determined on basis of spectroscopic evidence, as well as by comparing with literature data. Amongst the known metabolites, the 13C NMR assignment of 15-hydroxy-6,7-dihydrolactarazulene (3) is reported here for the first time. Moreover, 7-acetyl-4-methylazulene-1-carbaldehyde (5) displayed a moderate antibacterial activity against Staphylococcus aureus. Graphical Abstract *Digital image of L. deliciosus. Retrieved March 17, 2017 from https://upload.wikimedia.org/wikipedia/commons/e/e3/Lactarius_deliciosus_1_(1).jpg
Deletion of UA08_04451 (<i>talA</i>), encoding a hybrid PKS-NRPS, in <i>Talaromyces atroroseus</i> using CRISPR-Cas9.
No full textA) Co-transformation of gene-targeting plasmid pD-hyg-talA with a CRISPR-Cas9 vector. B) T. atroroseus transformed with pD-hyg-talA in the absence of a CRISPR-Cas9 vector. C) UHPLC-HRMS analysis of the extracts of wild type (WT) T. atroroseus along with a T. atroroseus talA deletion strain. Shown are EIC @ 528.3084 (±0.0100) for ZG-1494α (i), and EIC @ 510.2979 (±0.0100) for talaroconvolutin A (ii). We suspect the two peaks in (i) to represent both ZG-1494α and talaroconvolutin B. Note that EICs are based on [M+Na]+ adducts.</p
Interpretative and predictive modelling of Joint European Torus collisionality scans
No full textTransport modelling of Joint European Torus (JET) dimensionless collisionality scaling experiments in various operational scenarios is presented. Interpretative simulations at a fixed radial position are combined with predictive JETTO simulations of temperatures and densities, using the TGLF transport model. The model includes electromagnetic effects and collisions as well as (E)over-right-arrow x (b)over-right-arrow shear in Miller geometry. Focus is on particle transport and the role of the neutral beam injection (NBI) particle source for the density peaking. The experimental 3-point collisionality scans include L-mode, and H-mode (D and H and higher beta D plasma) plasmas in a total of 12 discharges. Experimental results presented in (Tala et al 2017 44th EPS Conf.) indicate that for the H-mode scans, the NBI particle source plays an important role for the density peaking, whereas for the L-mode scan, the influence of the particle source is small. In general, both the interpretative and predictive transport simulations support the experimental conclusions on the role of the NBI particle source for the 12 JET discharges
Pengaruh Model Guided Discovery Learning Terhadap Hasil Belajar Matematika Pecahan Siswa Kelas III SDN 20 Tala-Tala Kecamatan Bissappu Kabupaten Bantaeng
No full textThis study aims to determine the effect of Guided Discovery Learning on the learning outcomes of students in fractions of Class III SDN 20 Tala-Tala, Bissappu District, Bantaeng Regency. The type of research used in this study is experimental research, especially Pre-experimental. The sample in this study was 25 students. Data collection techniques were carried out using learning outcome tests and observation sheets. Data analysis techniques in this study were descriptive data analysis techniques and inferential data analysis techniques. The results of the study showed that there was an effect of the Guided Discovery Learning model on the mathematics learning outcomes of class III students of SDN 20 Tala-Tala, Bissappu District, Bantaeng Regency, as shown by the results of the t-test analysis showing that the significance value obtained (Sig = 0.001) was smaller than the specified alpha value of 0.05 (0.001 <0.05), then H0 was rejected and H1 was accepted, meaning that there was an effect of the Guided Discovery Learning model on the mathematics learning outcomes of class III students of SDN 20 Tala-Tala, Bissappu District, Bantaeng Regency. In addition, the results of learning mathematics before the implementation of the Guided Discovery Learning model in the pretest with an average value of 60, there was an increase in the posttest with an average value of 80.4. Based on the results obtained, it can be concluded that there is an influence of the Guided Discovery Learning model on the mathematics learning outcomes of class III students of SDN 20 Tala-Tala, Bissappu District, Bantaeng Regency.
Keywords: Guided Discovery Learning Model, Learning Outcomes, Mathematic
Pengaruh Model Guided Discovery Learning Terhadap Hasil Belajar Matematika Pecahan Siswa Kelas III SDN 20 Tala-Tala Kecamatan Bissappu Kabupaten Bantaeng
No full textThis study aims to determine the effect of Guided Discovery Learning on the learning outcomes of students in fractions of Class III SDN 20 Tala-Tala, Bissappu District, Bantaeng Regency. The type of research used in this study is experimental research, especially Pre-experimental. The sample in this study was 25 students. Data collection techniques were carried out using learning outcome tests and observation sheets. Data analysis techniques in this study were descriptive data analysis techniques and inferential data analysis techniques. The results of the study showed that there was an effect of the Guided Discovery Learning model on the mathematics learning outcomes of class III students of SDN 20 Tala-Tala, Bissappu District, Bantaeng Regency, as shown by the results of the t-test analysis showing that the significance value obtained (Sig = 0.001) was smaller than the specified alpha value of 0.05 (0.001 <0.05), then H0 was rejected and H1 was accepted, meaning that there was an effect of the Guided Discovery Learning model on the mathematics learning outcomes of class III students of SDN 20 Tala-Tala, Bissappu District, Bantaeng Regency. In addition, the results of learning mathematics before the implementation of the Guided Discovery Learning model in the pretest with an average value of 60, there was an increase in the posttest with an average value of 80.4. Based on the results obtained, it can be concluded that there is an influence of the Guided Discovery Learning model on the mathematics learning outcomes of class III students of SDN 20 Tala-Tala, Bissappu District, Bantaeng Regency.
Keywords: Guided Discovery Learning Model, Learning Outcomes, Mathematic
Handwritten biographical information on Paulina T. McClung Merritt
No full textA handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
No full textIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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