688 research outputs found
Online resources for mathematics in the scientific virtual reference desk
No full textThe present work briefly describes the Virtual Reference Desk for mathematics elaborated during the time I worked at the CERN Library (European Laboratory for Particle Physics or Laboratoire européen pour la physique des particules) in Geneva. This instrument is dedicated to the CERN librarians, with whom I have shared important moments of my professional career. In particular, I would like to gratefully acknowledge their valuable co-operation and assistance during our time spent working together. The Web metasource is comprised of three directories, annotated and interrelated with dual application: The first is intended as a work tool for librarians working in mathematics libraries, but above all for librarians of high energy physics, who more often than not must turn to mathematics and the use of mathematical applications and models for the physical sciences and in particular particle physics. The second is an on-line resource for mathematics; that is, a Virtual Reference Desk for the community of mathematicians, with whom I have been collaborating for some twenty years at the University of Padova. The bibliographical instrument is born from the need to have at our disposal a scientific Virtual Reference Desk created according to the needs of those working in physics and mathematics libraries – a tool which is comprised of materials collected during years of work as much as material available on-line through the use of new technologies
Intervista con Antonella De Robbio, Responsabile del Settore Progetti e Biblioteca Digitale del Centro d'Ateneo per le Biblioteche CAB dell' Università di Padova e Referente per il diritto d'autore del Sistema Bibliotecario di Ateneo
No full textThe interview with Antonella De Robbio – manager of the “Project Sector and Digital Library” for CAB (Centro di Ateneo per le Biblioteche) of the University of Padua and copyright expert for Sistema Bibliotecario di Ateneo – was published in Pinali news.
Antonella De Robbio answered the following questions:
1) How to deal with the issues of author’s intellectual and economic rights in the context of scientific publishing and digital library?
2) What is the influence of the digital approach on the traditional ways to create and disseminate scientific communication?
3) In your opinion, can the experiences of University Press and the Open Archives represent the path to follow in order to overcome the paradox that a scientific author is also the user of his publisher?
4) Which are the outcomes of the fight between copyright and copyleft?
5) Which of these approaches are more suitable to label the metaphor of the “Society of Knowledge”
Discriminant score for celiac disease based on immunohistochemical analysis of duodenal biopsies
No full textOBJECTIVES:
Celiac disease (CD) represents a spectrum, which includes cases with minor histological abnormalities (potential CD). The aim of this work is to evaluate the contribution of immunohistochemical analysis of duodenal biopsies to the diagnosis of gluten-related minor enteropathy.
METHODS:
Duodenal biopsies from 56 patients with untreated CD and 56 controls were analyzed for CD3 and γδ intraepithelial lymphocyte number, γδ/CD3 ratio, and density of CD25+ lamina propria cells. A discriminant equation was obtained by which 61 more biopsies with normal villous architecture were blindly evaluated.
RESULTS:
All of the immunohistochemical parameters were significantly different between patients with CD and controls. None of the single parameters showed sufficient specificity for CD. The combination of all of the 4 markers resulted in the following discriminant equation: discriminant score (Dscore) = (CD3 × 0.06) - (γδ × 0.119) + (CD25 × 0.012) + (γδ/CD3 × 0.131) - 4.709. Using this Dscore, patients were correctly classified as celiac or controls in 97.3% of the cases. When this equation was applied to a validation set of 61 patients with normal villous architecture and unknown diagnosis, 92.9% of those with a positive score turned out to be patients with potential CD. A normal score, however, did not exclude this condition.
CONCLUSIONS:
Immunohistochemistry represents a specific tool for the diagnosis of CD, but does lack sensitivity in detecting all of the potential CD cases
Literacy in Neapolitan Women's Convents in the Middle Ages and the Contribution of Digital Archives on Monasterium.Net
No full textAntonella Ambrosio seeks a viable way of carrying out research on this topic: the palaeographic analysis of the few available sources using a multidisciplinary approach that combines diplomatics, archival, and historical research. This approach ensures the appropriate contextualization of the source both historically and culturally. In "Literacy in Neapolitan Women's Convents: An Example of Female Handwriting in a Late Fifteenth-Century Accounts Ledger", Ambrosio provides a case study, analysing a single piece of handwriting evidence. The source is an accounts ledger from the Dominican convent of Santi Pietro e Sebastiano compiled in the second half of the fifteenth century, from 1485 to 1496. Using an analytical approach, the author has identified the handwriting of a particular (anonymous) nun from the convent; Ambrosio studies the script the nun used and formulates hypotheses about her cultural background and how she learned to write. The palaeographic analysis is fully contextualized thanks to the reconstruction of the old convent archive, a reconstruction helped by using digital technologies now accessible online at Monasterium.net. As Ambrosio's work demonstrates, technological advances may aid codicological work but careful palaeographic analysis is necessary to ascertain the participation of female scribes. In this case we witness the scribal development of a nun who began with a basic knowledge of writing and who went on to perform her practical task not well but adequately for the purpose
Intestinal deposits of IgA anti tissue transglutaminase antibodies in celiac children under two years of age.
No full text
Cis diidrossilazione asimmetrica catalitica di olefine mediante complessi di alcaloidi della china supportati su matrici polimeriche
No full textLiteracy in Neapolitan Women’s Convents: An Example of Female Handwriting in a Late Fifteenth-Century Accounts Ledger
No full textThis paper is about a research i on the literacy and writing skills of Neapolitan sisters in medieval convents, due to the lack of adequate historical study of such nuns and the extremely complex nature of the documentary sources. Surviving evidence is scattered far and wide, and the old convent archives have been dispersed. Given the state of the survivals, Antonella Ambrosio seeks a viable way of carrying out research on this topic: the palaeographic analysis of the few available sources using a multidisciplinary approach that combines diplomatics, archival, and historical research. This approach ensures the appropriate contextualization of the source both historically and culturally. In ‘Literacy in Neapolitan Women’s Convents: An Example of Female Handwriting in a Late Fifteenth-Century Accounts Ledger’, Ambrosio provides a case study, analysing a single piece of handwriting evidence. The source is an accounts ledger from the Dominican convent of Santi Pietro e Sebastiano compiled in the second half of the fifteenth century, from 1485 to 1496. Using an analytical approach, the author has identified the handwriting of a particular (anonymous) nun from the convent; Ambrosio studies the script the nun used and formulates hypotheses about her cultural background and how she learned to write. The palaeographic analysis is fully contextualized thanks to the reconstruction of the old convent archive, a reconstruction helped by using digital technologies now accessible online at Monasterium.net. As Ambrosio’s work demonstrates, technological advances may aid codicological work but careful palaeographic analysis is necessary to ascertain the participation of female scribes. In this case we witness the scribal development of a nun who began with a basic knowledge of writing and who went on to perform her practical task not well but adequately for the
purpose
How special are special sciences?
No full textThis essay deals with issues such as the unity of science, the autonomy of the special sciences, reductionism, physicalism, and the role that the concept of emergence plays in the debate about these topics. The author develops her point of view through critical examination of three significant perspectives held in contemporary epistemological discussion. Thus, according to Jerry Fodor, three theses are entailed by reductionism: the generality of physics, token physicalism, and reductionism itself (that is, the idea that every natural kind predicate of a special science is related to a natural kind predicate of physics). Fodor maintains that, in order to safeguard the autonomy of the special sciences, the reductionist thesis should be given up, as a consequence of the validity of the multiple realization thesis. Besides the generality of physics, only token physicalism is needed to guarantee both the autonomy of the special sciences and the unity of science on a physicalistic basis. However, reacting to Fodor’s thesis, Jaegwon Kim points out that adoption of token physicalism leads to consequences which are undesirable for the supporters of the autonomy of the special sciences. Moving from assumptions also shared by non-reductive physicalists, Kim argues that reductionism comes up again through “local reductions” and that, as a consequence, sciences such as psychology are devoid of any disciplinary unity. In the author’s view, Kim’s conclusions show that, in order to safeguard the autonomy of the special sciences, token-physicalism needs to be abandoned along with reductionism. In the context of present-day philosophy of science, John Dupre’s perspective is taken as an example of a position which gives up both of these conditions along with the unity of science thesis, as traditionally understood. The alternative to physicalism and to reductionism is an epistemological and ontological pluralism, according to which the different domains and levels of reality display autonomous characteristics and autonomous causal powers. But how should these latter be conceived? Does downward causation finds its place in the picture? The author’s aim in the final part of her essay is to show that Dupré’s allegiance to a liberalized form of empiricism is incompatible with an autonomous form of mental causation as well as with the most typical characteristics of the human being as a personal agent. The conclusion is drawn that in the particular case of psychology as the science of the mental, the last of Fodor’s conditions, the generality of physics, should also be rejected. Instead, a strong form of emergent property-dualism should, as a minimum, be accepted
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