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Young Sun Kim
학위논문(박사)--아주대학교 일반대학원 :의학과,2010. 2TABLE OF CONTENTS
ABSTRACT i
TABLE OF CONTENTS iii
LIST OF FIGURES v
ABBREVIATION vi
Ⅰ. INTRODUCTION 1
Ⅱ. MATERIALS AND METHODS 6
A. Materials 6
B. Subjects 6
C. Cell culture and viability 7
D. Transfection and depletion of siRNA 7
E. Immunocytochemistry 8
F. Co-immunoprecipitation and immunoblot analysis 8
G. Two-dimensional electrophoresis 9
H. Subcellular fractionation 10
I. Immunohistochemistry 10
J. Statistical analysis 11
Ⅲ. RESULTS 12
A. Localization of Prx III and Srx in A549 cells 12
B. Oxidation of Prx III in mink lung epithelial cells 12
C. Srx dependent regulation of Prx III oxidation in A549 cells 15
D. Srx is translocated into the mitochondria under oxidative stress 15
E. Overexpression of Prx I and III isoforms in human lung cancer 19
F. Nrf2 dependent expression of ARE-proteins in human lung cancer 19
G. Overexpression of Srx in human lung cancer 19
H. Survival of patients with lung cancer based on Srx expression 26
I. Expression of Srx in human lung cancer tissue 26
Ⅳ. DISCUSSION 28
Ⅴ. CONCLUSION 30
REFFERENCE 32
국문요약 40Maste
Author\u27s Response to Cherice Bock\u27s and Grace Ji-Sun Kim\u27s Reviews of Reframing the House
Thank you for these robust and thoughtful reviews. I am grateful to both Cherice Bock and Grace Ji-Sun Kim for being here and giving time and care towards my work
Christine Sun Kim: ASL and Deaf Identity in Art
This thesis investigates the relationship between d/Deaf identity, American Sign Language (ASL), and art through the groundbreaking work of Christine Sun Kim. As a deaf artist who utilizes ASL and visual art forms, Kim offers a unique perspective on the complexities of d/Deaf culture, communication, and identity. This study explores how Kim's art serves as a platform to challenge societal norms, redefine the concept of sound, and advocate for the recognition and appreciation of ASL as a legitimate language and cultural expression.Purchase College SUNYArt HistoryMaster of ArtsGuffey, Elizabet
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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