177,220 research outputs found
Parasitological survey on muflon population (ovis musimon) living in the Regional Park of Apuane Alps
No full textEffects of differential extraction of Verbena officinalis on rat models of inflammation, cicatrization and gastric damage
No full textPlanta Med. 2007 Mar;73(3):227-35. Epub 2007 Mar 12.
Effects of differential extraction of Verbena officinalis on rat models of inflammation, cicatrization and gastric damage.
Speroni E, Cervellati R, Costa S, Guerra MC, Utan A, Govoni P, Berger A, Müller A, Stuppner H.
Source
Dipartimento di Farmacologia, Università di Bologna, Bologna, Italy. [email protected]
Abstract
Verbena officinalis L. is used in folk medicine for the treatment of inflammatory disorders, skin burns, abrasions, and gastric diseases. Extracts obtained with different solvents (methanol, VoME; enriched flavonoids, VoEF; supercritical CO2, VoCO2) were evaluated for anti-inflammatory, gastroprotective and cicatrizing activities. Additionally, the antioxidant capacity was determined in vitro. In order to confirm the activities investigated, histological observations were performed. All extracts induce a remarkable anti-inflammatory activity. The gastric damage is significantly reduced by all extracts administered, whereby the most pronounced protection is observed for the VoCO2 and VoEF extracts. Finally, a wound healing effect is obtained particularly by the CO2 extract, suggesting the presence of some lipophilic active principles. Histological evidence confirms the results evaluated with the animal procedures. The results obtained after oral administration of V. officinalis extracts are also in agreement with the antioxidant capacity evaluated in vitro, confirming the relationship between pharmacological activities and antiradical efficacy
Clinical Management of Gingival Recessions with or Without Cervical Lesions: A Decisional Scheme Proposal
No full textBackground: Treatment of gingival recessions starts from an accurate diagnosis considering both periodontal tissue status and adjacent exposed dental tissues. Based on current scientific evidence and the authors’ clinical experience, a decisional scheme has been proposed for the management of gingival recession defects, with or without non-carious cervical lesions, taking into account gingival thickness and interproximal attachment levels. To illustrate its practical application, a series of representative clinical cases is presented, documenting the rationale and outcomes of the therapeutic decisions. Methods: According to the 2017 World Workshop Classification of Periodontal and Peri-Implant Diseases and Conditions, the gingival recession defect classifications have been used to build up a decision-making therapeutic process. Combined periodontal and restorative treatments in presence or absence of dental lesions have been performed. Results: In case of an identifiable cemento-enamel junction (CEJ) with or without non-carious cervical lesions (class A+ and class A−, respectively) and absence of interproximal attachment loss (RT1), flap approaches alone or in combination with connective tissue graft (CTG) were suggested. In case of an unidentifiable CEJ without cervical lesion (class B−), flap approaches alone were proposed in presence of adequate residual keratinized tissue (KT) and absence of interproximal attachment loss (RT1); if KT is extremely reduced, flap approaches + CTG may be performed. If the unidentifiable CEJ is associated with cervical lesions involving both root and crown surfaces (class B+), the combined restorative–periodontal treatment results as the most indicated approach. The adjunctive use of CTG should be also considered in presence of interproximal attachment loss (RT2 and RT3) and reduced gingival thickness (<1 mm). Conclusions: The proposed decisional scheme could be useful to address the clinicians during the decision-making process in the treatment of gingival recessions
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Seconda fase chirurgica: valutazione della mucosa peri-implantare in relazione alle diverse sistematiche implantari
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"Closing the R&D Gap, Evaluating the Sources of R&D Spending"
No full textBoth spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Ugo Speroni e i suoi epigoni: tra eresia e critica all'istituzione chiesa
No full textLe complesse vicende che portarono alla istituzione della diocesi di Alessandria si protrassero per diversi decenni, segnati da interventi della sede apostolica (Alessandro III e Innocenzo III) e dell'arcivescovo di Milano, entro la cui provincia ecclesiastica si collocavano le diocesi di cui e di Alessandria. Nel 1205, quando grazie a un nuovo intervento papale sembrava oramai prossima l'unione delle Chiese di Acqui e Alessandria sotto un unico vescovo (in tal modo Alessandria sarebbe divenuta sede episcopale), le resistenze degli ecclesiastici e del ceto consolare del comune di Acqui si fondarono su posizioni al limite dell'ortodossia, evidentemente maturate nell'ambiente delle scuole di diritto di area bolognese, dalle quali probabilmente veniva il più strenuo difensore dei diritti del Comune e della Chiesa di Acqui, magister Enrico. Alla metà del XII secolo, infatti, a Bologna si erano formati sia Ugo Speroni sia il magister Vacarius, colui che ne svelò l'eresia, e in esse si formarono numerosi esponenti del ceto consolare dei comuni padani, in buona parte costituito da esperti di diritto e giudici.The complex events that led to the institution of the diocese of Alessandria (Piedmont) lasted for several decades, marked by interventions by the Apostolic See (Alexander III and Innocent III) and the Archbishop of Milan, to whose ecclesiastical province both the dioceses of Acqui and Alessandria belonged. In 1205, when, thanks to a new papal intervention, the union of the Churches of Acqui and Alessandria under a single bishop seemed to be close (in this way Alessandria would become the episcopal see), strong resistance emerged from the ecclesiastics and the consular class of the town of Acqui. They expressed positions at the limit of orthodoxy, evidently matured in the environment of the law schools of the Bolognese area, from which probably came the most strenuous defender of the rights of the Commune and the Church of Acqui, magister Enrico. In the middle of the 12th century, in fact, both Ugo Speroni and magister Vacarius, the man who unveiled his heresy, had studied in Bologna, and in Bologna studied numerous exponents of the consular class of the Po Valley Communes, largely made up of legal experts and judges
Letter from R. R. Zellick, Assistant Trust Officer, Anglo California National Bank of San Francisco, to Joseph R. Goodman, October 2, 1942
No full textLetter from R. R. Zellick, Assistant Trust Officer at The Anglo California National Bank of San Francisco, to Joseph R. Goodman, regarding property owned by Dave Tatsuno. Zellick mentions a dispute between current tenants and Tatsuno, and that Tatsuno has asked Goodman to help locate trustworthy tenants.Personal correspondence, organizational records, government documents, publications, and other papers created or collected by Joseph R. Goodman documenting the forced removal and incarceration of Japanese Americans during World War II, as well as organized resistance to incarceration. Included in the collection are records of the Japanese Young Men's Christian Association and the Japanese American Citizens' League in San Francisco, including papers of the Japanese YMCA's executive secretary Lincoln Kanai; Sakai family papers; Goodman's correspondence to and from Japanese American incarcerees, organizations opposing forced removal and incarceration of Japanese Americans, the War Relocation Authority, and others; publications, photographs, and ephemera from the Topaz Relocation Center, where Goodman taught high school; War Relocation Authority records and publications; and newspaper clippings, pamphlets, and reports about forced removal and incarceration created by various government, religious, and civic organizations, in California and nationwide
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