5 research outputs found

    The Infiltration of the Cervical Carcinoma into the Vaginal Wall and the Relationship between the Cancer Infiltration into the Vaginal Wall and the Recurrence at the Vaginal Stump Section Ⅰ. The Infiltration of the Cervical Carcinoma into the Vaginal Wall Section Ⅱ. The Relationship between the Cancer Infiltration into the Vaginal Wall and the Recurrence at the Stump of the Vagina

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    For the carcinoma of the cervix the vaginal wall can be an object of cancer invasion, and it is closely associated with the postoperative recurrence at the stump of the vagina and also with the prognosis. In the present study the author carried out histological investigations of the vaginal wall of the patients who had Okabayashi's radical extensive hysterectomy in our clinic; and in Section Ⅰ are presented the results of investigations on the manner of cancer invasion into the vaginal wall in 160 recent unselected cases, and in Section Ⅱ the relationship between the recurrence at the vaginal stump and the vaginal-wall invasion as well as prophylactic effect of concomitant use of radium on the recurrence at the vaginal stump are described concerning 102 older specimens. Section 1. As for the invasion of the cervical carcinoma 62 cases (38.8%) out of 160 cases have been verified to have the cancer invasion, and there are some differences between the macroscopic and histological findings; and even in the 39 cases whose findings coincide with one another, in about one third of them the cancer invasion has been found 5 mm deeper in the histological examination than in the macroscopic examination. Next, the incidence of the cancer invasion into the vaginal wall is greater in more advanced age; more in the cervical canal cancer than cancer in the vaginal portion; more frequeut in Stage Ⅱ than in Stage Ⅰ; in a retrocessive type of growth; in the case where the outward appearance of the lesion is ulcerous; in the C.P.L. classification more in L-type; and more in the case where the cancer propagated to the endometrium than in the case without such apropagation; likewise in the case where the cancer propagated to the corpus uterus; and more frequent in the case with lymph node metastasis. As for the incidence of the cancer infiltration to various layers of the vaginal wall, the epidermal infiltration, the epidermal + submucous tissue, and the epidermal + submucous + muscular layers occupy two thirds of the total, and as for the invasion of each layer it is slightly more frequent in the epidermal layer. No difference can be observed in the frequency of the cancer invasion as regrads the sites of the vaginal wall (anterior, posterior, right, and left), and the cancer infiltration into the vaginal wall is always contiguous. Section Ⅱ. As regards the relationship between the cancer invasion into the vaginal wall and the recurrence at the stump of the vagina, out of 47 cases with recurrence 35 cases (74.4%) proved to have infiltration into the vaginal wall, and 8 cases had the cancer invasion penetrated as far as the vaginal stump. In those that had the recurrence at the vaginal stump the majority of them consisted of the vaginal cancer, cancer of Stage Ⅱ and Ⅲ, ulcerous exterior appearance, retrocessive type of growth, L Type, and moderately matured type. In comparing the 35 recurrent cases having the cancer invasion into the vaginal wall with those cases without recurrence at the vaginal stump, it has been clarified that the recurrence at the vaginal stump is more liable to occur in Type L with the vaginal-wall invasion and in the case whose distance between the tip of the infiltration and the stump end is less than 5 mm. Moreover, for the prevention of the recurrence at the vaginal stump taking the data in Section I into consideration, for the cases without vaginal-wall infiltration the conventional 3 cm-resection of the vaginal wall is indicated, while for the cases with vaginal-wall infiltration it is necessary to resect the vaginal wall over 1.8 cm. below the tip of macroscopic infiltration in view of the shrinkage of the specimens examined and the fact that histologically the infiltration goes deeper than macroscopic finding. In addition, when the cancer infiltration is marked and there is a danger of recurrence it is possible to prevent such a recurrence by radium therapy. In our laboratory the proximal dosage of radium used is 1,000 mg elh

    Opto-thermophoretic separation and trapping of plasmonic nanoparticles

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    Optical tweezers are powerful tools to trap, transport, and analyse individual nano-objects at dilute concentrations. However, it is still challenging to manipulate isolated single nano-objects in dense target environments with various kinds of materials, such as in living cells and mixtures of nanocolloids. In the present work, we have succeeded in the selective trapping of a few gold nanoshells with specific sizes and sweeping others out completely, only by irradiating the dense colloidal suspension of gold nanoshells with a focused near infrared continuous-wave (CW) laser. This was achieved by an interplay between optical gradient- and thermophoretic forces: while the gradient force traps the targets at the focal spot, the thermophoretic force pushes others out from the focal spot. The distance between the trapped targets and the separated others was longer than 20 mu m, allowing us to measure plasmonic scattering spectra of the trapped targets at a single-nanoparticle level. The present method paves a way for manipulating and analysing single nano-objects in dense mixtures of targets and various kinds of materials

    Saturation of azimuthal anisotropy in Au + Au collisions at sqrt(s_NN) = 62 - 200 GeV

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    432 authors, 7 pages text, 4 figures, REVTeX4. To be submitted to Physical Review Letters. Plain text data tables for the points plotted in figures for this and previous PHENIX publications are (or will be) publicly available at http://www.phenix.bnl.gov/papers.html - EINew measurements are presented for charged hadron azimuthal correlations at mid-rapidity in Au+Au collisions at sqrt(s_NN) = 62.4 and 200 GeV. They are compared to earlier measurements obtained at sqrt(s_NN) = 130 GeV and in Pb+Pb collisions at sqrt(s_NN) = 17.2 GeV. Sizeable anisotropies are observed with centrality and transverse momentum (p_T) dependence characteristic of elliptic flow (v_2). For a broad range of centralities, the observed magnitudes and trends of the differential anisotropy, v_2(p_T), change very little over the collision energy range sqrt(s_NN) = 62-200 GeV, indicating saturation of the excitation function for v_2 at these energies. Such a saturation may be indicative of the dominance of a very soft equation of state for sqrt(s_NN) = 62-200 GeV

    Formation of dense partonic matter in relativistic nucleus-nucleus collisions at RHIC: Experimental evaluation by the PHENIX collaboration

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    510 authors, 127 pages text, 56 figures, 1 tables, LaTeX. To be submitted to Nuclear Physics A as a regular article. Plain text data tables for the points plotted in figures for this and previous PHENIX publications are (or will be) publicly available at http://www.phenix.bnl.gov/papers.html - EIExtensive experimental data from high-energy nucleus-nucleus collisions were recorded using the PHENIX detector at the Relativistic Heavy Ion Collider (RHIC). The comprehensive set of measurements from the first three years of RHIC operation includes charged particle multiplicities, transverse energy, yield ratios and spectra of identified hadrons in a wide range of transverse momenta (p_T), elliptic flow, two-particle correlations, non-statistical fluctuations, and suppression of particle production at high p_T. The results are examined with an emphasis on implications for the formation of a new state of dense matter. We find that the state of matter created at RHIC cannot be described in terms of ordinary color neutral hadrons
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