682 research outputs found
Studies About Shevchenko is the Apogee of Literary-critical Shevchenkiana of Mykhailyna Kotsyubynska
No full textУ статті проаналізовано основні положення монографії видатного літературного критика, літературознавця М. Коцюбинської «Етюди про поетику Шевченка», визначено її місце в контексті літературно-критичної спад¬щини вченої. Простежено своєрідність науково-критичної рецепції феномену Шевченкового поетичного слова М. Коцюбинською. The article analyzes the main provisions of the monograph of the outstanding literary critic M. Kotsyubynska «Studies on Shevchenko’s poetics». It is determined its place in the context of literary-critical scientific heritage of the scientist. It is also traced the peculiarity of scientific and critical reception of the phenomenon of Shevchenko`s poetic heritage by M. Kotsyubynska. Through the prism of literary and critical views of scientist the article studies folklore and literary relations in the works of Taras Shevchenko: it is interpreted conditioning of Shevchenko`s poetics by folk component; it is developing a thesis on the relationship of folk songs and lyrics of the artist and his creative rethinking of folk motifs, themes, tools; it is determined the means of folk mastering by poet
The phenomenon of Yulia Tymoshenko in politics of Ukraine
No full textYulia Tymoshenko's leadership style and leadership are analy¬zed and described in this article. The author stated that political opposition was a natural element for Tymoshenko. Her time as Prime Minister was rather controversial, hence the assessements of her successes and failures propensities to vary. A description of Tymoshenko as a political party leader that included the way she chose people to work with was also given
"Yulia" by N. M. Karamzin: the first experience of creating a high society story in Russian literature
No full textВ статье рассматривается повесть Н. М. Карамзина "Юлия" в аспекте жанра. В ходе анализа приводятся дополнительные аргументы в пользу того, что "Юлия" является первой в отечественной литературе светской повестью, давшей начало перспективной жанровой традиции.In the article N. M. Karamzin's story "Yulia" is considered in aspect of a genre. During the analysis the author of the article brings the additional arguments in favor of the fact that "Yulia" is the first "high society story" in the domestic literature. Such a story opened a perspective genre tendency for further literature
"Yulia" by N. M. Karamzin: the first experience of creating a high society story in Russian literature
No full textВ статье рассматривается повесть Н. М. Карамзина "Юлия" в аспекте жанра. В ходе анализа приводятся дополнительные аргументы в пользу того, что "Юлия" является первой в отечественной литературе светской повестью, давшей начало перспективной жанровой традиции.In the article N. M. Karamzin's story "Yulia" is considered in aspect of a genre. During the analysis the author of the article brings the additional arguments in favor of the fact that "Yulia" is the first "high society story" in the domestic literature. Such a story opened a perspective genre tendency for further literature
UPAYA-UPAYA ROOM ATTENDANT DALAM MEMELIHARA KENYAMANAN TAMU DI VASA HOTEL SURABAYA
No full textThe goal to be achieved in this research is to find out the efforts made by the room
attendant in maintaining guest comfort at Vasa hotel Surabaya so that guests feel
happy, satisfied and want to visit again at Vasa Hotel Surabaya. The author makes
observations of the room attendant's efforts in maintaining guest comfort. The
author concludes that the efforts made by the room attendant in maintaining guest
comfort at Vasa hotel Surabaya are as follows: Maintain cleanliness, greet guests
and offer assistance, pause and say hello when meeting guests in the corridor area
or other places other than the room. , and provides towel folding services (towel
art) and has also carried out standard operating room attendant procedures
The roles of structural variability and amphiphilicity of TMC278/rilpivirine in mechanisms of HIV drug resistance avoidance and enhanced oral bioavailability
No full textNon-nucleoside reverse transcriptase inhibitors (NNRTIs) are small hydrophobic drug molecules that bind to a hydrophobic pocket of the HIV-1 reverse transcriptase (RT). A number of molecules from diarylpyrimidine (DAPY) class of NNRTIs have exceptional inhibitory properties against a broad range of known drug-resistant viral strains of HIV-1 and good oral bioavailability in humans. Biophysical, structural, and computational methods were applied to study DAPY NNRTIs with differing RT inhibitory and bioavailability properties with a goal to define the mechanisms by which the dual success of the selected DAPY NNRTIs is achieved.
Exceptional bioavailability properties of selected DAPY NNRTIs were hypothesized to stem from their ability to form self-formulated spherical drug aggregates, ~60 nm in diameter, that are trafficked from the gastrointestinal tract into systemic circulation through a lymphatic uptake pathway. Using dynamic light scattering (DLS) and electron microscopy (EM), formation of drug aggregates was demonstrated. Drug aggregation was determined to be surfactant independent. Based on this observation, it was hypothesized that the drug molecules were able to achieve surface-active properties. Using X-ray crystallography and all atom MD simulations of the drug aggregate/water interface it was determined that amphiphilic properties of the selected DAPY NNRTI molecules depend on the availability of the protonation site at the pyrimidine ring and structural variability of the drug molecules at the linker moieties.
Ability of the late phase DAPY NNRTI drug molecules to inhibit the broad range of drug-resistant HIV-1 mutants has been previously linked to the ability of the molecules to sample multiple binding modes within the binding pocket of HIV-1 RT (Das et al., 2004). Using computational methods, conformational sampling by TMC278 (a DAPY NNRTI in multiple Phase III trials) in the pocket of the wild-type and the mutant NNRTI-binding pocket (NNIBP) was evaluated. Results of this work support the concept that structural variability is important in overcoming drug resistance mechanisms.
We propose that the implementation of drug aggregation testing and the evaluation of torsional flexibility of highly hydrophobic compounds in the context of the lead identification strategies will allow for better selection of potent and orally bioavailable hydrophobic drug candidates.Ph.D.Includes bibliographical references (139-146)by Yulia Frenke
ESL Students’ Perceptions of Error Correction Techniques in Oral Production: A Level-Based Approach
No full textThe article reveals the findings from a survey examining students’ perceptions of corrective feedback involving six groups of the first- through fifth-year ESL students enrolled in Bachelor’s and Master’s programs in English Language and Literature, Applied Linguistics, International Law, and International Communication and Global Media. The study attempts to reveal students’ perceptions of corrective feedback, as well as its perceived effectiveness and psychological relevance, which are analyzed on the basis of students’ answers. The aim of this survey-based research was to explore ESL students’ preferences for the amount and type of corrective feedback in speaking/reading and develop a method to help educators effectively choose the types of corrective feedback on the basis of their students’ level of English. In order to reinforce the study with substantial theoretical evidence, each type of corrective feedback was characterized on the basis of a rigorous review of related evidence-focused literature. The survey, which was administered to 78 ESL students at Taras Shevchenko National University of Kyiv and Khmelnytskyi National University, Ukraine, demonstrated a number of discrepancies in students’ preferences and attitudes. Their responses constituted grounds for assessing and ranking the prevalent verbal correction techniques in ESL teaching according to their perceived relevance. The implications of the current study could be taken into consideration by ESL teachers for determining an optimal set of error correction techniques in their own classrooms on the basis of their students’ level of English
Scanning tunneling microscopy and spectroscopy of topological materials and heterostructures in thin films and devices
No full textThis dissertation reports the results of scanning tunneling microscopy experiments probing the physics of thin films of topological materials. A 3D topological insulator Bi2Te3 and a 2D topological insulator WTe2, grown epitaxially, are studied with atomic resolution, and their physics is probed using in-situ back gating. The development of the back-gating process in a scanning tunneling microscope is one of the main results of this work and is reported in detail. The band structure of the monolayer WTe2 is observed to be drastically changing upon the application of electric field through the back gate. The complex effect of the gate-induced electric field on monolayer WTe2 is explored and discussed. A study of the spatial extent of 1D edge states of WTe2 is presented. A new process combining nanopatterned superconductors and topological materials is proposed and implemented. The proposed geometry in devices suitable for scanning tunneling microscopy studies opens up many new possibilities to explore the proximity effect in topological materials for future Majorana platform realization.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2022-05-01The student, Yulia Maximenko, accepted the attached license on 2020-04-02 at 03:39.The student, Yulia Maximenko, submitted this Dissertation for approval on 2020-04-02 at 03:46.This Dissertation was approved for publication on 2020-04-06 at 14:22.DSpace SAF Submission Ingestion Package generated from Vireo submission #14932 on 2020-08-25 at 17:39:50Made available in DSpace on 2020-08-27T00:49:52Z (GMT). No. of bitstreams: 2
MAXIMENKO-DISSERTATION-2020.pdf: 21100430 bytes, checksum: 60c71fa0134ef0ad1f200befa3b5c960 (MD5)
LICENSE.txt: 4212 bytes, checksum: 062c18cbaa69f350904e432c0d667dbc (MD5)
Previous issue date: 2020-04-06Embargo set by: Seth Robbins for item 115855
Lift date: 2022-08-27T00:50:22Z
Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemEmbargo set by: Seth Robbins for item 115855
Lift date: 2022-08-27T00:51:40Z
Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemAuthor requested closed access (OA after 2yrs) in Vireo ETD systemLimite
APHERP symposium session IV : Higher education, job opportunities and transgenerational inequality
No full textPresented Titles: Massification and Transnationalisation of Higher Education: Challenges for Graduate Employment and Transgenerational Inequality in China [Authors: Joshua Ka-ho Mok; Guo-guo Ke; Tian Zhen] Expanding Higher Education during Economic Downturns: Why China’s Lessons are Hard to Learn From? [Authors: Wing-kit Chan; Jiarun Li] Multiple Factors Affecting Graduate Employability: What Implications for Graduates? [Authors: Yuzhuo Cai; Yulia Shumilova] Graduate Employability and Labour Market Relevance of Norwegian Higher Education: Perspectives from Students [Author: Dian Liu
- …
